This is a Validated Antibody Database (VAD) review about human TGN46, based on 30 published articles (read how Labome selects the articles), using TGN46 antibody in all methods. It is aimed to help Labome visitors find the most suited TGN46 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
TGN46 synonym: TGN38; TGN46; TGN48; TGN51; TTGN2; hTGN46; hTGN48; hTGN51

Bio-Rad
domestic sheep polyclonal
  • other; human; 1:40; loading ...; fig 9e, s1b
Bio-Rad TGN46 antibody (Bio-Rad, AHP500GT) was used in other on human samples at 1:40 (fig 9e, s1b). J Clin Med (2021) ncbi
domestic sheep polyclonal
  • immunocytochemistry; human; 1:200; loading ...; fig 4
Bio-Rad TGN46 antibody (Bio-Rad, AHP500G) was used in immunocytochemistry on human samples at 1:200 (fig 4). elife (2020) ncbi
domestic sheep polyclonal
  • immunocytochemistry; human; loading ...; fig 7d
Bio-Rad TGN46 antibody (Serotec, AHP500G) was used in immunocytochemistry on human samples (fig 7d). J Cell Biol (2019) ncbi
domestic sheep polyclonal
  • immunocytochemistry; human; 1:100; loading ...; fig s1c
Bio-Rad TGN46 antibody (AbD Serotec/Bio-Rad, AHP500) was used in immunocytochemistry on human samples at 1:100 (fig s1c). EMBO J (2018) ncbi
domestic sheep polyclonal
  • immunocytochemistry; human; loading ...; fig 2d
Bio-Rad TGN46 antibody (Bio-Rad, AHP500) was used in immunocytochemistry on human samples (fig 2d). J Cell Sci (2017) ncbi
domestic sheep polyclonal
  • immunocytochemistry; human; 1:500; loading ...; fig 6c
Bio-Rad TGN46 antibody (AbD Serotec, AHP500GT) was used in immunocytochemistry on human samples at 1:500 (fig 6c). J Cell Biol (2017) ncbi
domestic sheep polyclonal
  • immunocytochemistry; human; 1:400; loading ...; fig 1a
In order to study the function of the RAB6 secretory pathway melanosome formation and maturation, Bio-Rad TGN46 antibody (AbD Serotec, AHP500GT) was used in immunocytochemistry on human samples at 1:400 (fig 1a). Nat Commun (2017) ncbi
domestic sheep polyclonal
  • immunocytochemistry; human; 1:200; loading ...; fig 3B
In order to identify cellular processes that regulate HIF1alpha, Bio-Rad TGN46 antibody (AbD Serotec, AHP500GT) was used in immunocytochemistry on human samples at 1:200 (fig 3B). elife (2017) ncbi
domestic sheep polyclonal
  • immunocytochemistry; human; 1:300; loading ...; fig 1c
Bio-Rad TGN46 antibody (AbD Serotec, AHP500) was used in immunocytochemistry on human samples at 1:300 (fig 1c). BMC Biol (2017) ncbi
domestic sheep polyclonal
  • immunocytochemistry; human; 1:200; loading ...; fig 7a
In order to examine if SMSr-SAM is structurally and functionally related to the SAM domain of diacylglycerol kinase DGKd, Bio-Rad TGN46 antibody (AbD Serotec, AHP500) was used in immunocytochemistry on human samples at 1:200 (fig 7a). Sci Rep (2017) ncbi
domestic sheep polyclonal
  • immunocytochemistry; human; loading ...; fig s8
In order to show that 2-hydroxyoleic acid treatment alters cell signaling and intracellular transport, Bio-Rad TGN46 antibody (AbD Serotec, AHP500G) was used in immunocytochemistry on human samples (fig s8). Oncotarget (2016) ncbi
domestic sheep polyclonal
  • immunocytochemistry; human; 1:400; fig 2
  • immunocytochemistry; African green monkey; 1:400; fig 1
Bio-Rad TGN46 antibody (Biorad, AHP500GT) was used in immunocytochemistry on human samples at 1:400 (fig 2) and in immunocytochemistry on African green monkey samples at 1:400 (fig 1). Nat Commun (2016) ncbi
domestic sheep polyclonal
  • immunocytochemistry; mouse; 1:4000; fig 4
  • other; African green monkey; 1:200; fig 1
  • immunocytochemistry; African green monkey; 1:4000; fig 1
In order to learn the requirement of palmitoylation at the Golgi by activation of STING, Bio-Rad TGN46 antibody (Serotec, AHP500G) was used in immunocytochemistry on mouse samples at 1:4000 (fig 4), in other on African green monkey samples at 1:200 (fig 1) and in immunocytochemistry on African green monkey samples at 1:4000 (fig 1). Nat Commun (2016) ncbi
domestic sheep polyclonal
  • immunocytochemistry; African green monkey; 1:1000; loading ...; fig 5a
Bio-Rad TGN46 antibody (AbD Serotec, AHP500G) was used in immunocytochemistry on African green monkey samples at 1:1000 (fig 5a). Sci Rep (2016) ncbi
domestic sheep polyclonal
  • immunocytochemistry; human; fig 7
In order to analyze control of MT1-MMP endocytic and E-cadherin polarized golgi trafficking to promote invasive breast cancer programs by RAB2A, Bio-Rad TGN46 antibody (Serotec, AHP500GT) was used in immunocytochemistry on human samples (fig 7). EMBO Rep (2016) ncbi
domestic sheep polyclonal
  • western blot; human; loading ...; fig 3d
Bio-Rad TGN46 antibody (AbD Serotec, AHP500G) was used in western blot on human samples (fig 3d). J Cell Biol (2016) ncbi
domestic sheep polyclonal
  • western blot; human; fig 1
In order to analyze the human breast cancer cell lines MDA-MB-231 and MCF7 in human breast cancer cell lines to decipher distinct biochemical pools of golgi phosphoprotein 3, Bio-Rad TGN46 antibody (AbD Serotec, AHP500G) was used in western blot on human samples (fig 1). PLoS ONE (2016) ncbi
domestic sheep polyclonal
  • western blot; human; fig 5
Bio-Rad TGN46 antibody (AbD Serotec, AHP500GT) was used in western blot on human samples (fig 5). Biol Open (2016) ncbi
Invitrogen
domestic rabbit polyclonal
In order to map the topography of the human papillomavirus L2 protein during infection, Invitrogen TGN46 antibody (Thermo Scientific, PA5-23068) was used . J Virol (2015) ncbi
mouse monoclonal (2F7.1)
  • immunohistochemistry - frozen section; rat; 1:200
  • immunohistochemistry; rat; 1:200
In order to study mRNA granule formation following experimental permanent focal cerebral ischemia, Invitrogen TGN46 antibody (Thermo Scientific, MA3-063) was used in immunohistochemistry - frozen section on rat samples at 1:200 and in immunohistochemistry on rat samples at 1:200. Transl Stroke Res (2013) ncbi
mouse monoclonal (2F7.1)
  • immunohistochemistry - frozen section; rat; 1:200
  • immunohistochemistry; rat; 1:200
  • western blot; rat; 1:250
In order to investigate the relationship between organelle systems and mRNA granules in neurons after ischemia, Invitrogen TGN46 antibody (Thermo Scientific, MA3-063) was used in immunohistochemistry - frozen section on rat samples at 1:200, in immunohistochemistry on rat samples at 1:200 and in western blot on rat samples at 1:250. Neuroscience (2011) ncbi
mouse monoclonal (2F7.1)
  • immunocytochemistry; African green monkey; fig 1
In order to identify the intramolecular region involved in the specific localization of NHE6 and NHE7, Invitrogen TGN46 antibody (Zymed, 2F7.1) was used in immunocytochemistry on African green monkey samples (fig 1). J Membr Biol (2010) ncbi
Novus Biologicals
domestic rabbit polyclonal (12)
  • immunohistochemistry - frozen section; human; fig s2
Novus Biologicals TGN46 antibody (Novus biological, NBP1- 03495) was used in immunohistochemistry - frozen section on human samples (fig s2). Science (2020) ncbi
domestic rabbit polyclonal (13H12)
  • immunocytochemistry; human; 1:100; fig 3
Novus Biologicals TGN46 antibody (Novus Biologicals, NBP1-49643) was used in immunocytochemistry on human samples at 1:100 (fig 3). Nature (2016) ncbi
domestic rabbit polyclonal (13H12)
In order to assess adeno-associated virus transduction and its requirement for syntaxin 5-dependent retrograde transport to the trans-Golgi network, Novus Biologicals TGN46 antibody (Novus, NBP1-49643) was used . J Virol (2015) ncbi
Santa Cruz Biotechnology
mouse monoclonal (B-6)
  • immunocytochemistry; mouse; loading ...; fig 6e
Santa Cruz Biotechnology TGN46 antibody (Santa Cruz, sc-166594) was used in immunocytochemistry on mouse samples (fig 6e). Front Mol Neurosci (2017) ncbi
mouse monoclonal (G-9)
  • immunocytochemistry; mouse; loading ...; fig s11o
Santa Cruz Biotechnology TGN46 antibody (SantaCruz, sc-271624) was used in immunocytochemistry on mouse samples (fig s11o). EBioMedicine (2016) ncbi
MilliporeSigma
domestic rabbit polyclonal
  • immunocytochemistry; human; 1:300; loading ...; fig s4i
MilliporeSigma TGN46 antibody (Sigma-Aldrich, T7576) was used in immunocytochemistry on human samples at 1:300 (fig s4i). Science (2018) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; human; 1:1000; loading ...; fig s3a
MilliporeSigma TGN46 antibody (Sigma-Aldrich, T7576) was used in immunohistochemistry on human samples at 1:1000 (fig s3a). Autophagy (2016) ncbi
domestic rabbit polyclonal
  • immunoprecipitation; human; fig 6d
MilliporeSigma TGN46 antibody (Sigma, T7576) was used in immunoprecipitation on human samples (fig 6d). elife (2016) ncbi
mouse monoclonal (TGN46-52)
  • western blot; human; fig 6d
MilliporeSigma TGN46 antibody (Sigma, SAB4200235) was used in western blot on human samples (fig 6d). elife (2016) ncbi
Articles Reviewed
  1. Hess M, Krainer I, Filipek P, Witting B, Gutleben K, Vietor I, et al. Advanced Microscopy for Liver and Gut Ultrastructural Pathology in Patients with MVID and PFIC Caused by MYO5B Mutations. J Clin Med. 2021;10: pubmed publisher
  2. Barnat M, Capizzi M, Aparicio E, Boluda S, Wennagel D, Kacher R, et al. Huntington's disease alters human neurodevelopment. Science. 2020;369:787-793 pubmed publisher
  3. Butt B, Owen D, Jeffries C, Ivanova L, Hill C, Houghton J, et al. Insights into herpesvirus assembly from the structure of the pUL7:pUL51 complex. elife. 2020;9: pubmed publisher
  4. Judith D, Jefferies H, Boeing S, Frith D, Snijders A, Tooze S. ATG9A shapes the forming autophagosome through Arfaptin 2 and phosphatidylinositol 4-kinase IIIβ. J Cell Biol. 2019;218:1634-1652 pubmed publisher
  5. Gut G, Herrmann M, Pelkmans L. Multiplexed protein maps link subcellular organization to cellular states. Science. 2018;361: pubmed publisher
  6. Jimenez Orgaz A, Kvainickas A, Nägele H, Denner J, Eimer S, Dengjel J, et al. Control of RAB7 activity and localization through the retromer-TBC1D5 complex enables RAB7-dependent mitophagy. EMBO J. 2018;37:235-254 pubmed publisher
  7. Stevenson N, Bergen D, Skinner R, Kague E, Martin Silverstone E, Robson Brown K, et al. Giantin-knockout models reveal a feedback loop between Golgi function and glycosyltransferase expression. J Cell Sci. 2017;130:4132-4143 pubmed publisher
  8. Zhang X, Jiang S, Mitok K, Li L, Attie A, Martin T. BAIAP3, a C2 domain-containing Munc13 protein, controls the fate of dense-core vesicles in neuroendocrine cells. J Cell Biol. 2017;216:2151-2166 pubmed publisher
  9. Patwardhan A, Bardin S, Miserey Lenkei S, Larue L, Goud B, Raposo G, et al. Routing of the RAB6 secretory pathway towards the lysosome related organelle of melanocytes. Nat Commun. 2017;8:15835 pubmed publisher
  10. Vogelgesang S, Niebert S, Renner U, Mobius W, Hülsmann S, Manzke T, et al. Analysis of the Serotonergic System in a Mouse Model of Rett Syndrome Reveals Unusual Upregulation of Serotonin Receptor 5b. Front Mol Neurosci. 2017;10:61 pubmed publisher
  11. Miles A, Burr S, Grice G, Nathan J. The vacuolar-ATPase complex and assembly factors, TMEM199 and CCDC115, control HIF1? prolyl hydroxylation by regulating cellular iron levels. elife. 2017;6: pubmed publisher
  12. Wong M, Gillingham A, Munro S. The golgin coiled-coil proteins capture different types of transport carriers via distinct N-terminal motifs. BMC Biol. 2017;15:3 pubmed publisher
  13. Cabukusta B, Kol M, Kneller L, Hilderink A, Bickert A, Mina J, et al. ER residency of the ceramide phosphoethanolamine synthase SMSr relies on homotypic oligomerization mediated by its SAM domain. Sci Rep. 2017;7:41290 pubmed publisher
  14. Torgersen M, Klokk T, Kavaliauskiene S, Klose C, Simons K, Skotland T, et al. The anti-tumor drug 2-hydroxyoleic acid (Minerval) stimulates signaling and retrograde transport. Oncotarget. 2016;7:86871-86888 pubmed publisher
  15. Jian J, Tian Q, Hettinghouse A, Zhao S, Liu H, Wei J, et al. Progranulin Recruits HSP70 to β-Glucocerebrosidase and Is Therapeutic Against Gaucher Disease. EBioMedicine. 2016;13:212-224 pubmed publisher
  16. Hernandez Tiedra S, Fabrias G, Davila D, Salanueva I, Casas J, Montes L, et al. Dihydroceramide accumulation mediates cytotoxic autophagy of cancer cells via autolysosome destabilization. Autophagy. 2016;12:2213-2229 pubmed
  17. Pagliuso A, Valente C, Giordano L, Filograna A, Li G, Circolo D, et al. Golgi membrane fission requires the CtBP1-S/BARS-induced activation of lysophosphatidic acid acyltransferase ?. Nat Commun. 2016;7:12148 pubmed publisher
  18. Mukai K, Konno H, Akiba T, Uemura T, Waguri S, Kobayashi T, et al. Activation of STING requires palmitoylation at the Golgi. Nat Commun. 2016;7:11932 pubmed publisher
  19. Mkhikian H, Mortales C, Zhou R, Khachikyan K, Wu G, Haslam S, et al. Golgi self-correction generates bioequivalent glycans to preserve cellular homeostasis. elife. 2016;5: pubmed publisher
  20. Wegel E, Göhler A, Lagerholm B, Wainman A, Uphoff S, Kaufmann R, et al. Imaging cellular structures in super-resolution with SIM, STED and Localisation Microscopy: A practical comparison. Sci Rep. 2016;6:27290 pubmed publisher
  21. Kajiho H, Kajiho Y, Frittoli E, Confalonieri S, Bertalot G, Viale G, et al. RAB2A controls MT1-MMP endocytic and E-cadherin polarized Golgi trafficking to promote invasive breast cancer programs. EMBO Rep. 2016;17:1061-80 pubmed publisher
  22. Crevenna A, Blank B, Maiser A, Emin D, Prescher J, Beck G, et al. Secretory cargo sorting by Ca2+-dependent Cab45 oligomerization at the trans-Golgi network. J Cell Biol. 2016;213:305-14 pubmed publisher
  23. Tenorio M, Ross B, Luchsinger C, Rivera Dictter A, Arriagada C, Acuña D, et al. Distinct Biochemical Pools of Golgi Phosphoprotein 3 in the Human Breast Cancer Cell Lines MCF7 and MDA-MB-231. PLoS ONE. 2016;11:e0154719 pubmed publisher
  24. Fearnley G, Smith G, Abdul Zani I, Yuldasheva N, Mughal N, Homer Vanniasinkam S, et al. VEGF-A isoforms program differential VEGFR2 signal transduction, trafficking and proteolysis. Biol Open. 2016;5:571-83 pubmed publisher
  25. Pillay S, Meyer N, Puschnik A, Davulcu O, Diep J, Ishikawa Y, et al. An essential receptor for adeno-associated virus infection. Nature. 2016;530:108-12 pubmed publisher
  26. DiGiuseppe S, Keiffer T, Bienkowska Haba M, Luszczek W, Guion L, Muller M, et al. Topography of the Human Papillomavirus Minor Capsid Protein L2 during Vesicular Trafficking of Infectious Entry. J Virol. 2015;89:10442-52 pubmed publisher
  27. Nonnenmacher M, Cintrat J, Gillet D, Weber T. Syntaxin 5-dependent retrograde transport to the trans-Golgi network is required for adeno-associated virus transduction. J Virol. 2015;89:1673-87 pubmed publisher
  28. Lewis M, Jamison J, Dunbar J, DeGracia D. mRNA redistribution during permanent focal cerebral ischemia. Transl Stroke Res. 2013;4:604-17 pubmed publisher
  29. Jamison J, Szymanski J, DeGracia D. Organelles do not colocalize with mRNA granules in post-ischemic neurons. Neuroscience. 2011;199:394-400 pubmed publisher
  30. Fukura N, Ohgaki R, Matsushita M, Nakamura N, Mitsui K, Kanazawa H. A membrane-proximal region in the C-terminal tail of NHE7 is required for its distribution in the trans-Golgi network, distinct from NHE6 localization at endosomes. J Membr Biol. 2010;234:149-58 pubmed publisher