This is a Validated Antibody Database (VAD) review about human TFEB, based on 25 published articles (read how Labome selects the articles), using TFEB antibody in all methods. It is aimed to help Labome visitors find the most suited TFEB antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
TFEB synonym: ALPHATFEB; BHLHE35; TCFEB

Knockout validation
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot knockout validation; human; 1:1000; loading ...; fig 2k
Cell Signaling Technology TFEB antibody (Cell Signaling, 4240) was used in western blot knockout validation on human samples at 1:1000 (fig 2k). J Immunother Cancer (2021) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot knockout validation; human; loading ...; fig 3b
Cell Signaling Technology TFEB antibody (CST, 4240) was used in western blot knockout validation on human samples (fig 3b). PLoS ONE (2020) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • immunocytochemistry; mouse; 1:400; loading ...; fig 4g
  • western blot; mouse; 1:1000; loading ...; fig 8k
  • western blot knockout validation; human; 1:1000; loading ...; fig e3f
  • immunocytochemistry; human; 1:400; loading ...; fig 4c
Cell Signaling Technology TFEB antibody (Cell Signaling, 4240) was used in immunocytochemistry on mouse samples at 1:400 (fig 4g), in western blot on mouse samples at 1:1000 (fig 8k), in western blot knockout validation on human samples at 1:1000 (fig e3f) and in immunocytochemistry on human samples at 1:400 (fig 4c). EMBO Mol Med (2019) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot knockout validation; human; 1:1000; fig s25c
Cell Signaling Technology TFEB antibody (Cell Signaling Technology, 4240) was used in western blot knockout validation on human samples at 1:1000 (fig s25c). Nat Commun (2016) ncbi
MyBioSource
mouse monoclonal (319C2a)
  • immunocytochemistry; mouse; loading ...; fig s2c
MyBioSource TFEB antibody (MyBioSource, MBS120432) was used in immunocytochemistry on mouse samples (fig s2c). J Clin Invest (2017) ncbi
mouse monoclonal (319C2a)
  • immunohistochemistry; human; loading ...; fig 8
MyBioSource TFEB antibody (MyBiosource, MBS120432) was used in immunohistochemistry on human samples (fig 8). Cell Death Dis (2017) ncbi
mouse monoclonal (319C2a)
  • immunohistochemistry - paraffin section; human; loading ...; fig s1
MyBioSource TFEB antibody (MyBioSource, MBS120432) was used in immunohistochemistry - paraffin section on human samples (fig s1). Biochim Biophys Acta (2016) ncbi
mouse monoclonal (319C2a)
  • immunocytochemistry; mouse; 1:50
MyBioSource TFEB antibody (MyBiosources, MBS120432) was used in immunocytochemistry on mouse samples at 1:50. Methods Cell Biol (2015) ncbi
mouse monoclonal (319C2a)
  • western blot; mouse; fig 4a
  • immunocytochemistry; rat; fig 2b
  • western blot; rat; fig 2
In order to elucidate the autophagic status in spinobulbar muscular atrophy using both cellular and mouse models, MyBioSource TFEB antibody (MyBioSource, MBS120432) was used in western blot on mouse samples (fig 4a), in immunocytochemistry on rat samples (fig 2b) and in western blot on rat samples (fig 2). Hum Mol Genet (2014) ncbi
Abcam
domestic goat polyclonal
  • western blot; human; loading ...; fig 1i
Abcam TFEB antibody (Abcam, ab2636) was used in western blot on human samples (fig 1i). J Clin Invest (2019) ncbi
domestic goat polyclonal
  • immunocytochemistry; mouse; loading ...; fig 4b
  • western blot; mouse; loading ...; fig 4a
Abcam TFEB antibody (Abcam, ab2636) was used in immunocytochemistry on mouse samples (fig 4b) and in western blot on mouse samples (fig 4a). Nature (2016) ncbi
domestic goat polyclonal
  • western blot; mouse; 1:1000
In order to investigate thyroid hormone-mediated autophagy in skeletal muscle, Abcam TFEB antibody (Abcam, ab2636) was used in western blot on mouse samples at 1:1000. Endocrinology (2016) ncbi
domestic goat polyclonal
  • western blot; human; loading ...; fig 5a
Abcam TFEB antibody (Abcam, ab2636) was used in western blot on human samples (fig 5a). J Neurochem (2016) ncbi
Santa Cruz Biotechnology
mouse monoclonal (C-6)
  • western blot; rat; 1:50; loading ...; fig 8a
Santa Cruz Biotechnology TFEB antibody (Santa Cruz Biotechnology, sc-166736) was used in western blot on rat samples at 1:50 (fig 8a). Neuropharmacology (2019) ncbi
mouse monoclonal (C-6)
  • western blot; human; loading ...; fig 3b
In order to study the promotion of lysosomal biogenesis and autophagy by nucleus-translocated ACSS2, Santa Cruz Biotechnology TFEB antibody (Santa cruz, Sc166736) was used in western blot on human samples (fig 3b). Mol Cell (2017) ncbi
mouse monoclonal (17)
  • proximity ligation assay; human; 1:50; fig 2
Santa Cruz Biotechnology TFEB antibody (Santa Cruz, sc-101532) was used in proximity ligation assay on human samples at 1:50 (fig 2). Nat Cell Biol (2015) ncbi
Abnova
mouse monoclonal (S1)
  • western blot; mouse; fig 1
In order to analyze the mitigation that increases PHF1 levels and lipofuscin puncta and rescues memory deficits by TFEB overexpression in the P301S model of tauopathy, Abnova TFEB antibody (Abnova, H00007942-M01) was used in western blot on mouse samples (fig 1). Eneuro (2016) ncbi
mouse monoclonal (S1)
  • western blot; human; fig 3e
Abnova TFEB antibody (Abnova, H00007942-M01) was used in western blot on human samples (fig 3e). J Virol (2015) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot; human; 1:2000; loading ...; fig 4c
Cell Signaling Technology TFEB antibody (Cell Signaling, 4240S) was used in western blot on human samples at 1:2000 (fig 4c). Antioxidants (Basel) (2021) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; human; 1:200; loading ...; fig 4c, e4a, 5c
  • western blot; human; 1:1000; loading ...; fig 5a, 5b
Cell Signaling Technology TFEB antibody (Cell signaling, 4240S) was used in immunocytochemistry on human samples at 1:200 (fig 4c, e4a, 5c) and in western blot on human samples at 1:1000 (fig 5a, 5b). EMBO Mol Med (2021) ncbi
domestic rabbit monoclonal (E9S8N)
  • western blot; human; 1:3000; loading ...; fig 5h
Cell Signaling Technology TFEB antibody (Cell Signaling Technology, 37681) was used in western blot on human samples at 1:3000 (fig 5h). Nat Commun (2021) ncbi
domestic rabbit monoclonal (E9S8N)
  • western blot; human; 1:1000; loading ...; fig 3c
Cell Signaling Technology TFEB antibody (Cell Signaling, 37681) was used in western blot on human samples at 1:1000 (fig 3c). J Immunother Cancer (2021) ncbi
domestic rabbit polyclonal
  • western blot knockout validation; human; 1:1000; loading ...; fig 2k
Cell Signaling Technology TFEB antibody (Cell Signaling, 4240) was used in western blot knockout validation on human samples at 1:1000 (fig 2k). J Immunother Cancer (2021) ncbi
domestic rabbit monoclonal (E9S8N)
  • western blot; mouse; loading ...; fig 4b
Cell Signaling Technology TFEB antibody (CST, 37681) was used in western blot on mouse samples (fig 4b). Cell Death Dis (2021) ncbi
domestic rabbit polyclonal
  • western blot knockout validation; human; loading ...; fig 3b
Cell Signaling Technology TFEB antibody (CST, 4240) was used in western blot knockout validation on human samples (fig 3b). PLoS ONE (2020) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; mouse; 1:400; loading ...; fig 4g
  • western blot; mouse; 1:1000; loading ...; fig 8k
  • western blot knockout validation; human; 1:1000; loading ...; fig e3f
  • immunocytochemistry; human; 1:400; loading ...; fig 4c
Cell Signaling Technology TFEB antibody (Cell Signaling, 4240) was used in immunocytochemistry on mouse samples at 1:400 (fig 4g), in western blot on mouse samples at 1:1000 (fig 8k), in western blot knockout validation on human samples at 1:1000 (fig e3f) and in immunocytochemistry on human samples at 1:400 (fig 4c). EMBO Mol Med (2019) ncbi
domestic rabbit monoclonal (E9S8N)
  • western blot; human; 1:500; loading ...; fig 4m
Cell Signaling Technology TFEB antibody (Cell Signaling, 37681) was used in western blot on human samples at 1:500 (fig 4m). EMBO Mol Med (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 5b
Cell Signaling Technology TFEB antibody (Cell Signaling Technology, 4240) was used in western blot on human samples (fig 5b). Autophagy (2018) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; human; 1:50; loading ...; fig 3b
  • western blot; human; 1:1000; loading ...; fig 4a
Cell Signaling Technology TFEB antibody (Cell Signaling, 4240) was used in immunocytochemistry on human samples at 1:50 (fig 3b) and in western blot on human samples at 1:1000 (fig 4a). Nat Commun (2018) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 6a
Cell Signaling Technology TFEB antibody (cell signalling, 4240) was used in western blot on human samples (fig 6a). Cell Death Dis (2017) ncbi
domestic rabbit polyclonal
  • western blot knockout validation; human; 1:1000; fig s25c
Cell Signaling Technology TFEB antibody (Cell Signaling Technology, 4240) was used in western blot knockout validation on human samples at 1:1000 (fig s25c). Nat Commun (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; fig 1
In order to analyze the mitigation that increases PHF1 levels and lipofuscin puncta and rescues memory deficits by TFEB overexpression in the P301S model of tauopathy, Cell Signaling Technology TFEB antibody (Cell Signaling Technology, 4240) was used in western blot on mouse samples (fig 1). Eneuro (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 4
Cell Signaling Technology TFEB antibody (Cell Signaling, 4240) was used in western blot on human samples (fig 4). Biochim Biophys Acta (2016) ncbi
MilliporeSigma
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 5a
MilliporeSigma TFEB antibody (Sigma-Aldrich, SAB4503154) was used in western blot on human samples at 1:1000 (fig 5a). Am J Pathol (2018) ncbi
Articles Reviewed
  1. Ikari S, Yang Q, Lu S, Liu Y, Hao F, Tong G, et al. Quercetin in Tartary Buckwheat Induces Autophagy against Protein Aggregations. Antioxidants (Basel). 2021;10: pubmed publisher
  2. Soldati C, Lopez Fabuel I, Wanderlingh L, García Macia M, Monfregola J, Esposito A, et al. Repurposing of tamoxifen ameliorates CLN3 and CLN7 disease phenotype. EMBO Mol Med. 2021;13:e13742 pubmed publisher
  3. Alesi N, Akl E, Khabibullin D, Liu H, Nidhiry A, Garner E, et al. TSC2 regulates lysosome biogenesis via a non-canonical RAGC and TFEB-dependent mechanism. Nat Commun. 2021;12:4245 pubmed publisher
  4. Wu Q, Tian A, Li B, Leduc M, Forveille S, Hamley P, et al. IGF1 receptor inhibition amplifies the effects of cancer drugs by autophagy and immune-dependent mechanisms. J Immunother Cancer. 2021;9: pubmed publisher
  5. Tan A, PRASAD R, Jho E. TFEB regulates pluripotency transcriptional network in mouse embryonic stem cells independent of autophagy-lysosomal biogenesis. Cell Death Dis. 2021;12:343 pubmed publisher
  6. Ballesteros Álvarez J, Dilshat R, Fock V, Möller K, Karl L, Larue L, et al. MITF and TFEB cross-regulation in melanoma cells. PLoS ONE. 2020;15:e0238546 pubmed publisher
  7. Chen G, Xie W, Nah J, Sauvat A, Liu P, Pietrocola F, et al. 3,4-Dimethoxychalcone induces autophagy through activation of the transcription factors TFE3 and TFEB. EMBO Mol Med. 2019;11:e10469 pubmed publisher
  8. Pierzynowska K, Podlacha M, Gaffke L, Majkutewicz I, Mantej J, Wegrzyn A, et al. Autophagy-dependent mechanism of genistein-mediated elimination of behavioral and biochemical defects in the rat model of sporadic Alzheimer's disease. Neuropharmacology. 2019;148:332-346 pubmed publisher
  9. Liu N, Luo J, Kuang D, Xu S, Duan Y, Xia Y, et al. Lactate inhibits ATP6V0d2 expression in tumor-associated macrophages to promote HIF-2α-mediated tumor progression. J Clin Invest. 2019;129:631-646 pubmed publisher
  10. Wang W, Xia Z, Farre J, Subramani S. TRIM37 deficiency induces autophagy through deregulating the MTORC1-TFEB axis. Autophagy. 2018;14:1574-1585 pubmed publisher
  11. Hsu C, Lee E, Gordon K, Paz E, Shen W, Ohnishi K, et al. MAP4K3 mediates amino acid-dependent regulation of autophagy via phosphorylation of TFEB. Nat Commun. 2018;9:942 pubmed publisher
  12. Lee S, Bazick H, Chittoor Vinod V, Al Salihi M, Xia G, Notterpek L. Elevated Peripheral Myelin Protein 22, Reduced Mitotic Potential, and Proteasome Impairment in Dermal Fibroblasts from Charcot-Marie-Tooth Disease Type 1A Patients. Am J Pathol. 2018;188:728-738 pubmed publisher
  13. Bartolomeo R, Cinque L, De Leonibus C, Forrester A, Salzano A, Monfregola J, et al. mTORC1 hyperactivation arrests bone growth in lysosomal storage disorders by suppressing autophagy. J Clin Invest. 2017;127:3717-3729 pubmed publisher
  14. Li X, Yu W, Qian X, Xia Y, Zheng Y, Lee J, et al. Nucleus-Translocated ACSS2 Promotes Gene Transcription for Lysosomal Biogenesis and Autophagy. Mol Cell. 2017;66:684-697.e9 pubmed publisher
  15. Nascimbeni A, Fanin M, Angelini C, Sandri M. Autophagy dysregulation in Danon disease. Cell Death Dis. 2017;8:e2565 pubmed publisher
  16. Zhang X, Cheng X, Yu L, Yang J, Calvo R, Patnaik S, et al. MCOLN1 is a ROS sensor in lysosomes that regulates autophagy. Nat Commun. 2016;7:12109 pubmed publisher
  17. Shin H, Kim H, Oh S, Lee J, Kee M, Ko H, et al. AMPK-SKP2-CARM1 signalling cascade in transcriptional regulation of autophagy. Nature. 2016;534:553-7 pubmed publisher
  18. Wang H, Wang R, Carrera I, Xu S, Lakshmana M. TFEB Overexpression in the P301S Model of Tauopathy Mitigates Increased PHF1 Levels and Lipofuscin Puncta and Rescues Memory Deficits. Eneuro. 2016;3: pubmed publisher
  19. Angelini C, Nascimbeni A, Cenacchi G, Tasca E. Lipolysis and lipophagy in lipid storage myopathies. Biochim Biophys Acta. 2016;1862:1367-73 pubmed publisher
  20. Lesmana R, Sinha R, Singh B, Zhou J, Ohba K, Wu Y, et al. Thyroid Hormone Stimulation of Autophagy Is Essential for Mitochondrial Biogenesis and Activity in Skeletal Muscle. Endocrinology. 2016;157:23-38 pubmed publisher
  21. Ivankovic D, Chau K, Schapira A, Gegg M. Mitochondrial and lysosomal biogenesis are activated following PINK1/parkin-mediated mitophagy. J Neurochem. 2016;136:388-402 pubmed publisher
  22. Ju X, Yan Y, Liu Q, Li N, Sheng M, Zhang L, et al. Neuraminidase of Influenza A Virus Binds Lysosome-Associated Membrane Proteins Directly and Induces Lysosome Rupture. J Virol. 2015;89:10347-58 pubmed publisher
  23. Medina D, Di Paola S, Peluso I, Armani A, De Stefani D, Venditti R, et al. Lysosomal calcium signalling regulates autophagy through calcineurin and ​TFEB. Nat Cell Biol. 2015;17:288-99 pubmed
  24. Settembre C, Medina D. TFEB and the CLEAR network. Methods Cell Biol. 2015;126:45-62 pubmed publisher
  25. Chua J, Reddy S, Merry D, Adachi H, Katsuno M, Sobue G, et al. Transcriptional activation of TFEB/ZKSCAN3 target genes underlies enhanced autophagy in spinobulbar muscular atrophy. Hum Mol Genet. 2014;23:1376-86 pubmed publisher