This is a Validated Antibody Database (VAD) review about human TET2, based on 14 published articles (read how Labome selects the articles), using TET2 antibody in all methods. It is aimed to help Labome visitors find the most suited TET2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
TET2 synonym: KIAA1546; MDS

Knockout validation
Abcam
domestic rabbit polyclonal
  • western blot knockout validation; mouse; loading ...; fig s4c
Abcam TET2 antibody (Abcam, ab124297) was used in western blot knockout validation on mouse samples (fig s4c). Nat Struct Mol Biol (2021) ncbi
Abcam
domestic rabbit polyclonal
  • western blot knockout validation; mouse; loading ...; fig s4c
Abcam TET2 antibody (Abcam, ab124297) was used in western blot knockout validation on mouse samples (fig s4c). Neurology (2021) ncbi
Abcam
domestic rabbit polyclonal
  • western blot knockout validation; mouse; loading ...; fig s4c
Abcam TET2 antibody (Abcam, ab124297) was used in western blot knockout validation on mouse samples (fig s4c). Neurology (2021) ncbi
Abcam
domestic rabbit polyclonal
  • western blot knockout validation; mouse; fig 7a
Abcam TET2 antibody (Abcam, 94580) was used in western blot knockout validation on mouse samples (fig 7a). J Exp Med (2017) ncbi
Active Motif
mouse monoclonal (21F11)
  • western blot knockout validation; human; 1:500; loading ...; fig 1b
  • immunocytochemistry; human; 1:100; loading ...; fig 2f
Active Motif TET2 antibody (Active motif, 61389) was used in western blot knockout validation on human samples at 1:500 (fig 1b) and in immunocytochemistry on human samples at 1:100 (fig 2f). Oncogene (2019) ncbi
Abcam
domestic rabbit polyclonal
  • immunohistochemistry; human; loading ...; fig 7d
  • western blot; human; loading ...; fig 1f
Abcam TET2 antibody (Abcam, ab94580) was used in immunohistochemistry on human samples (fig 7d) and in western blot on human samples (fig 1f). Cell Death Discov (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; loading ...; fig 1c
Abcam TET2 antibody (Abcam, ab124297) was used in immunohistochemistry - frozen section on mouse samples (fig 1c). Circulation (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; loading ...; fig 1a
  • western blot; human; loading ...; fig 2a
Abcam TET2 antibody (Abcam, ab94580) was used in immunohistochemistry - paraffin section on human samples (fig 1a) and in western blot on human samples (fig 2a). Circulation (2021) ncbi
domestic rabbit polyclonal
  • western blot knockout validation; mouse; loading ...; fig s4c
Abcam TET2 antibody (Abcam, ab124297) was used in western blot knockout validation on mouse samples (fig s4c). Nat Struct Mol Biol (2021) ncbi
domestic rabbit polyclonal
  • western blot knockout validation; mouse; loading ...; fig s4c
Abcam TET2 antibody (Abcam, ab124297) was used in western blot knockout validation on mouse samples (fig s4c). Neurology (2021) ncbi
domestic rabbit polyclonal
  • western blot knockout validation; mouse; loading ...; fig s4c
Abcam TET2 antibody (Abcam, ab124297) was used in western blot knockout validation on mouse samples (fig s4c). Neurology (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 1h
Abcam TET2 antibody (Abcam, ab124297) was used in western blot on mouse samples (fig 1h). Aging (Albany NY) (2020) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; loading ...; fig 1c
  • western blot; mouse; loading ...; fig 1a
  • immunohistochemistry; human; loading ...; fig 1c
  • western blot; human; loading ...; fig 1a
Abcam TET2 antibody (Abcam, ab94580) was used in immunohistochemistry on mouse samples (fig 1c), in western blot on mouse samples (fig 1a), in immunohistochemistry on human samples (fig 1c) and in western blot on human samples (fig 1a). Nat Commun (2018) ncbi
domestic rabbit polyclonal
  • western blot; mouse; fig 3c
Abcam TET2 antibody (Abcam, ab94580) was used in western blot on mouse samples (fig 3c). Proc Natl Acad Sci U S A (2017) ncbi
domestic rabbit polyclonal
  • western blot knockout validation; mouse; fig 7a
Abcam TET2 antibody (Abcam, 94580) was used in western blot knockout validation on mouse samples (fig 7a). J Exp Med (2017) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig s5d
Abcam TET2 antibody (Abcam, ab94580) was used in western blot on mouse samples (fig s5d). Cell Stem Cell (2017) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; loading ...; fig st1
In order to find head injury increases galectin-3 expression in microglia and also increases the released form of galectin-3 in the cerebrospinal fluid after 24 hours, Abcam TET2 antibody (Abcam, ab94580) was used in immunohistochemistry - frozen section on mouse samples (fig st1). Sci Rep (2017) ncbi
Active Motif
mouse monoclonal (21F11)
  • western blot knockout validation; human; 1:500; loading ...; fig 1b
  • immunocytochemistry; human; 1:100; loading ...; fig 2f
Active Motif TET2 antibody (Active motif, 61389) was used in western blot knockout validation on human samples at 1:500 (fig 1b) and in immunocytochemistry on human samples at 1:100 (fig 2f). Oncogene (2019) ncbi
mouse monoclonal (21F11)
  • western blot; human; loading ...; fig 2c
Active Motif TET2 antibody (Active Motif, 61389) was used in western blot on human samples (fig 2c). Oncotarget (2017) ncbi
mouse monoclonal (21F11)
  • western blot; human; fig 6
In order to identify factors that contribute to monocyte-to-macrophage differentiation, Active Motif TET2 antibody (Active Motif, 61389) was used in western blot on human samples (fig 6). Epigenetics Chromatin (2016) ncbi
Articles Reviewed
  1. Bao Y, Bai M, Zhu H, Yuan Y, Wang Y, Zhang Y, et al. DNA demethylase Tet2 suppresses cisplatin-induced acute kidney injury. Cell Death Discov. 2021;7:167 pubmed publisher
  2. Ostriker A, Xie Y, Chakraborty R, Sizer A, Bai Y, Ding M, et al. TET2 Protects Against Vascular Smooth Muscle Cell Apoptosis and Intimal Thickening in Transplant Vasculopathy. Circulation. 2021;144:455-470 pubmed publisher
  3. He C, Bozler J, Janssen K, Wilusz J, Garcia B, Schorn A, et al. TET2 chemically modifies tRNAs and regulates tRNA fragment levels. Nat Struct Mol Biol. 2021;28:62-70 pubmed publisher
  4. Mantegazza R, Wolfe G, Muppidi S, Wiendl H, Fujita K, O Brien F, et al. Post-intervention Status in Patients With Refractory Myasthenia Gravis Treated With Eculizumab During REGAIN and Its Open-Label Extension. Neurology. 2021;96:e610-e618 pubmed publisher
  5. Shah S, Vázquez do Campo R, Kumar N, McKeon A, Flanagan E, Klein C, et al. Paraneoplastic Myeloneuropathies: Clinical, Oncologic, and Serologic Accompaniments. Neurology. 2021;96:e632-e639 pubmed publisher
  6. Huang F, Sun J, Chen W, He X, Zhu Y, Dong H, et al. HDAC4 inhibition disrupts TET2 function in high-risk MDS and AML. Aging (Albany NY). 2020;12:16759-16774 pubmed publisher
  7. Zhang J, Tan P, Guo L, Gong J, Ma J, Li J, et al. p53-dependent autophagic degradation of TET2 modulates cancer therapeutic resistance. Oncogene. 2019;38:1905-1919 pubmed publisher
  8. Yang R, Yu T, Kou X, Gao X, Chen C, Liu D, et al. Tet1 and Tet2 maintain mesenchymal stem cell homeostasis via demethylation of the P2rX7 promoter. Nat Commun. 2018;9:2143 pubmed publisher
  9. Yosefzon Y, David C, Tsukerman A, Pnueli L, Qiao S, Boehm U, et al. An epigenetic switch repressing Tet1 in gonadotropes activates the reproductive axis. Proc Natl Acad Sci U S A. 2017;114:10131-10136 pubmed publisher
  10. Ma S, Wan X, Deng Z, Shi L, Hao C, Zhou Z, et al. Epigenetic regulator CXXC5 recruits DNA demethylase Tet2 to regulate TLR7/9-elicited IFN response in pDCs. J Exp Med. 2017;214:1471-1491 pubmed publisher
  11. Choi J, Clement K, Huebner A, Webster J, Rose C, Brumbaugh J, et al. DUSP9 Modulates DNA Hypomethylation in Female Mouse Pluripotent Stem Cells. Cell Stem Cell. 2017;20:706-719.e7 pubmed publisher
  12. Yip P, Carrillo Jimenez A, King P, Vilalta A, Nomura K, Chau C, et al. Galectin-3 released in response to traumatic brain injury acts as an alarmin orchestrating brain immune response and promoting neurodegeneration. Sci Rep. 2017;7:41689 pubmed publisher
  13. Gong F, Guo Y, Niu Y, Jin J, Zhang X, Shi X, et al. Epigenetic silencing of TET2 and TET3 induces an EMT-like process in melanoma. Oncotarget. 2017;8:315-328 pubmed publisher
  14. Wallner S, Schröder C, Leitão E, Berulava T, Haak C, Beißer D, et al. Epigenetic dynamics of monocyte-to-macrophage differentiation. Epigenetics Chromatin. 2016;9:33 pubmed publisher