This is a Validated Antibody Database (VAD) review about human TERT, based on 15 published articles (read how Labome selects the articles), using TERT antibody in all methods. It is aimed to help Labome visitors find the most suited TERT antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
TERT synonym: CMM9; DKCA2; DKCB4; EST2; PFBMFT1; TCS1; TP2; TRT; hEST2; hTRT

Abcam
domestic rabbit monoclonal (Y182)
  • immunohistochemistry - paraffin section; human; 1:150; loading ...; fig 5a
  • western blot; human; loading ...; fig 2c
Abcam TERT antibody (Abcam, ab32020) was used in immunohistochemistry - paraffin section on human samples at 1:150 (fig 5a) and in western blot on human samples (fig 2c). Front Oncol (2022) ncbi
domestic rabbit monoclonal (Y182)
  • western blot; human; loading ...; fig 4e
Abcam TERT antibody (Abcam, ab32020) was used in western blot on human samples (fig 4e). Sci Adv (2021) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; human; loading ...; fig 1c
Abcam TERT antibody (Abcam, ab230527) was used in immunocytochemistry on human samples (fig 1c). Int J Mol Sci (2021) ncbi
domestic rabbit monoclonal (Y182)
  • immunoprecipitation; human; fig 4c
  • western blot; human; 1:1000; fig 1b
Abcam TERT antibody (Abcam, ab32020) was used in immunoprecipitation on human samples (fig 4c) and in western blot on human samples at 1:1000 (fig 1b). Aging (Albany NY) (2020) ncbi
domestic rabbit monoclonal (Y182)
  • western blot; human; loading ...; fig 1c
Abcam TERT antibody (Abcam, ab32020) was used in western blot on human samples (fig 1c). Sci Adv (2019) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:25; fig 1e, 1h
  • western blot; human; 1:1000; loading ...; fig 2h
Abcam TERT antibody (Abcam, ab183105) was used in immunohistochemistry - paraffin section on human samples at 1:25 (fig 1e, 1h) and in western blot on human samples at 1:1000 (fig 2h). Sci Rep (2017) ncbi
domestic rabbit monoclonal (Y182)
  • immunocytochemistry; human; fig 2b
In order to track telomerase trafficking in nuclei of living human cells, Abcam TERT antibody (Abcam, Ab32020) was used in immunocytochemistry on human samples (fig 2b). Cell (2016) ncbi
domestic rabbit polyclonal
  • western blot; human
  • immunohistochemistry; mouse; fig 2
Abcam TERT antibody (Abcam, ab183105) was used in western blot on human samples and in immunohistochemistry on mouse samples (fig 2). Int J Mol Med (2016) ncbi
Invitrogen
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; rat; 1:50; loading ...; fig 3a
  • immunocytochemistry; rat; 1:100; fig 3b, s2
  • western blot; rat; 1:1000; fig 3c, s1b
Invitrogen TERT antibody (Invitrogen, PA5-116024) was used in immunohistochemistry - paraffin section on rat samples at 1:50 (fig 3a), in immunocytochemistry on rat samples at 1:100 (fig 3b, s2) and in western blot on rat samples at 1:1000 (fig 3c, s1b). J Cell Mol Med (2022) ncbi
mouse monoclonal (2C4)
  • immunohistochemistry - paraffin section; human; 1:150; loading ...; fig 1
In order to determine the relationship of a hTERT polymorphism in the development of oral squamous cell carcinoma., Invitrogen TERT antibody (Thermo Fisher Scientific Inc., 2C4) was used in immunohistochemistry - paraffin section on human samples at 1:150 (fig 1). J Oral Sci (2016) ncbi
mouse monoclonal (2C4)
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 1c
In order to test if telomerase reverse transcriptase modulates proliferative vascular remodeling, Invitrogen TERT antibody (Thermo Scientific, MA5-16034) was used in immunohistochemistry - paraffin section on mouse samples (fig 1c). Arterioscler Thromb Vasc Biol (2017) ncbi
mouse monoclonal (2C4)
  • flow cytometry; human; 1:200; loading ...
In order to characterize dysfunctional clonal T cells from patients withy multiple myeloma, Invitrogen TERT antibody (Thermo Scientific, 2C4) was used in flow cytometry on human samples at 1:200. Leukemia (2016) ncbi
Abbexa
domestic sheep polyclonal
  • immunoprecipitation; human; loading ...; fig 2c
Abbexa TERT antibody (Abbexa, abx120550) was used in immunoprecipitation on human samples (fig 2c). Front Oncol (2022) ncbi
domestic sheep polyclonal
  • immunoprecipitation; human; loading ...; fig 1c
Abbexa TERT antibody (Abbexa, abx120550) was used in immunoprecipitation on human samples (fig 1c). Sci Adv (2019) ncbi
Rockland Immunochemicals
domestic rabbit polyclonal
  • western blot; human; loading ...; fig s1a
In order to test if telomerase reverse transcriptase modulates proliferative vascular remodeling, Rockland Immunochemicals TERT antibody (Rockland Immunochemicals, 600-401-252) was used in western blot on human samples (fig s1a). Arterioscler Thromb Vasc Biol (2017) ncbi
domestic rabbit polyclonal
  • immunoprecipitation; human; fig 1c
  • immunocytochemistry; human; 0.5 ug/ml
In order to test if NOL1activates transcription of cyclin D1, Rockland Immunochemicals TERT antibody (Rockland, 600-401-252) was used in immunoprecipitation on human samples (fig 1c) and in immunocytochemistry on human samples at 0.5 ug/ml. J Cell Sci (2016) ncbi
Novus Biologicals
mouse monoclonal (2C4)
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 3a
  • western blot; mouse; loading ...; fig 3b
Novus Biologicals TERT antibody (Novus Biologicals, NB100-317) was used in immunohistochemistry - paraffin section on mouse samples (fig 3a) and in western blot on mouse samples (fig 3b). Sci Rep (2016) ncbi
Santa Cruz Biotechnology
mouse monoclonal (C-12)
  • western blot; human; loading ...; fig 7c
Santa Cruz Biotechnology TERT antibody (SantaCruz, sc-377511) was used in western blot on human samples (fig 7c). BMC Cancer (2014) ncbi
Articles Reviewed
  1. Wang R, Li J, Zhang C, Guan X, Qin B, Jin R, et al. Lactate Dehydrogenase B Is Required for Pancreatic Cancer Cell Immortalization Through Activation of Telomerase Activity. Front Oncol. 2022;12:821620 pubmed publisher
  2. Hu Q, Liu X, Liu Z, Liu Z, Zhang H, Zhang Q, et al. Dexmedetomidine reduces enteric glial cell injury induced by intestinal ischaemia-reperfusion injury through mitochondrial localization of TERT. J Cell Mol Med. 2022;26:2594-2606 pubmed publisher
  3. Lee J, Hong J, Zhang Z, de la Peña Avalos B, Proietti C, Deamicis A, et al. Regulation of telomere homeostasis and genomic stability in cancer by N 6-adenosine methylation (m6A). Sci Adv. 2021;7: pubmed publisher
  4. Evtushenko N, Beilin A, Dashinimaev E, Ziganshin R, Kosykh A, Perfilov M, et al. hTERT-Driven Immortalization of RDEB Fibroblast and Keratinocyte Cell Lines Followed by Cre-Mediated Transgene Elimination. Int J Mol Sci. 2021;22: pubmed publisher
  5. Tang S, Wu W, Wan H, Wu X, Chen H. Knockdown of NHP2 inhibits hepatitis B virus X protein-induced hepatocarcinogenesis via repressing TERT expression and disrupting the stability of telomerase complex. Aging (Albany NY). 2020;12:19365-19374 pubmed publisher
  6. Cheng L, Yuan B, Ying S, Niu C, Mai H, Guan X, et al. PES1 is a critical component of telomerase assembly and regulates cellular senescence. Sci Adv. 2019;5:eaav1090 pubmed publisher
  7. Yang H, Zhang H, Zhong Y, Wang Q, Yang L, Kang H, et al. Concomitant underexpression of TGFBR2 and overexpression of hTERT are associated with poor prognosis in cervical cancer. Sci Rep. 2017;7:41670 pubmed publisher
  8. Carkić J, Nikolic N, Radojevic Skodric S, Kuzmanovic Pficer J, Brajović G, Antunović M, et al. The role of TERT-CLPTM1L SNPs, hTERT expression and telomere length in the pathogenesis of oral squamous cell carcinoma. J Oral Sci. 2016;58:449-458 pubmed publisher
  9. Endorf E, Qing H, Aono J, Terami N, Doyon G, Hyzny E, et al. Telomerase Reverse Transcriptase Deficiency Prevents Neointima Formation Through Chromatin Silencing of E2F1 Target Genes. Arterioscler Thromb Vasc Biol. 2017;37:301-311 pubmed publisher
  10. Schmidt J, Zaug A, Cech T. Live Cell Imaging Reveals the Dynamics of Telomerase Recruitment to Telomeres. Cell. 2016;166:1188-1197.e9 pubmed publisher
  11. Liu Q, Sun Y, Lv Y, Le Z, Xin Y, Zhang P, et al. TERT alleviates irradiation-induced late rectal injury by reducing hypoxia-induced ROS levels through the activation of NF-?B and autophagy. Int J Mol Med. 2016;38:785-93 pubmed publisher
  12. Suen H, Brown R, Yang S, Weatherburn C, Ho P, Woodland N, et al. Multiple myeloma causes clonal T-cell immunosenescence: identification of potential novel targets for promoting tumour immunity and implications for checkpoint blockade. Leukemia. 2016;30:1716-24 pubmed publisher
  13. Hong J, Lee J, Chung I. Telomerase activates transcription of cyclin D1 gene through an interaction with NOL1. J Cell Sci. 2016;129:1566-79 pubmed publisher
  14. Wu X, Yang Y, Li W, Cheng Y, Li X, Huang C, et al. Telomerase reverse transcriptase acts in a feedback loop with NF-κB pathway to regulate macrophage polarization in alcoholic liver disease. Sci Rep. 2016;6:18685 pubmed publisher
  15. Zakaria M, Khan I, Mani P, Chattopadhyay P, Sarkar D, Sinha S. Combination of hepatocyte specific delivery and transformation dependent expression of shRNA inducing transcriptional gene silencing of c-Myc promoter in hepatocellular carcinoma cells. BMC Cancer. 2014;14:582 pubmed publisher