This is a Validated Antibody Database (VAD) review about human TCOF1, based on 4 published articles (read how Labome selects the articles), using TCOF1 antibody in all methods. It is aimed to help Labome visitors find the most suited TCOF1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
TCOF1 synonym: MFD1; TCS; TCS1; treacle; treacle protein; Treacher Collins syndrome protein; Treacher Collins-Franceschetti syndrome 1; nucleolar trafficking phosphoprotein

Proteintech Group
rabbit polyclonal
  • western blot; human; 1:250; fig 5
Proteintech Group TCOF1 antibody (Proteintech, 11003-1-AP) was used in western blot on human samples at 1:250 (fig 5). Nature (2015) ncbi
rabbit polyclonal
  • immunocytochemistry; human; 1:100
  • western blot; human; 1:1000
Proteintech Group TCOF1 antibody (Proteintech, 11003-1-AP1) was used in immunocytochemistry on human samples at 1:100 and in western blot on human samples at 1:1000. Proc Natl Acad Sci U S A (2014) ncbi
rabbit polyclonal
  • immunocytochemistry; human; 1:200
  • western blot; human; 1:1000
Proteintech Group TCOF1 antibody (Proteintec, 11003-1-AP) was used in immunocytochemistry on human samples at 1:200 and in western blot on human samples at 1:1000. PLoS ONE (2014) ncbi
Santa Cruz Biotechnology
mouse monoclonal (H-6)
  • immunocytochemistry; human; 1:100
Santa Cruz Biotechnology TCOF1 antibody (Santa Cruz Biotechnology, sc-374536) was used in immunocytochemistry on human samples at 1:100. Proc Natl Acad Sci U S A (2014) ncbi
Sigma-Aldrich
rabbit polyclonal
  • western blot; human; 1:500; fig 6
Sigma-Aldrich TCOF1 antibody (Sigma, HPA038237) was used in western blot on human samples at 1:500 (fig 6). Nat Cell Biol (2014) ncbi
Articles Reviewed
  1. Werner A, Iwasaki S, McGourty C, Medina Ruiz S, Teerikorpi N, Fedrigo I, et al. Cell-fate determination by ubiquitin-dependent regulation of translation. Nature. 2015;525:523-7 pubmed publisher
  2. Ciccia A, Huang J, Izhar L, Sowa M, Harper J, Elledge S. Treacher Collins syndrome TCOF1 protein cooperates with NBS1 in the DNA damage response. Proc Natl Acad Sci U S A. 2014;111:18631-6 pubmed publisher
  3. Larsen D, Hari F, Clapperton J, Gwerder M, Gutsche K, Altmeyer M, et al. The NBS1-Treacle complex controls ribosomal RNA transcription in response to DNA damage. Nat Cell Biol. 2014;16:792-803 pubmed publisher
  4. Park A, Won S, Pentecost M, Bartkowski W, Lee B. CRISPR/Cas9 allows efficient and complete knock-in of a destabilization domain-tagged essential protein in a human cell line, allowing rapid knockdown of protein function. PLoS ONE. 2014;9:e95101 pubmed publisher