This is a Validated Antibody Database (VAD) review about human TBX3, based on 8 published articles (read how Labome selects the articles), using TBX3 antibody in all methods. It is aimed to help Labome visitors find the most suited TBX3 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
TBX3 synonym: TBX3-ISO; UMS; XHL; T-box transcription factor TBX3; T-box protein 3; bladder cancer related protein XHL

Invitrogen
rabbit polyclonal
  • western blot; human; 1:25; fig 3
  • western blot; mouse; 1:25; fig 3
In order to study a promising biomarker and key regulator of the oncogenic phenotype of a diverse range of sarcoma subtypes called T-box transcription factor 3, Invitrogen TBX3 antibody (Zymed, 42-4800) was used in western blot on human samples at 1:25 (fig 3) and in western blot on mouse samples at 1:25 (fig 3). Oncogenesis (2016) ncbi
rabbit polyclonal
  • western blot; human
In order to investigate the role of TBX2 and TBX3 on the anti-proliferative and pro-migratory roles of TGF-beta1, Invitrogen TBX3 antibody (Zymed, 42-4800) was used in western blot on human samples . J Biol Chem (2014) ncbi
rabbit polyclonal
  • chromatin immunoprecipitation; mouse; loading ...; fig 7b
In order to report that TBX3 is an upstream regulator of the mesendoderm transcriptional program during gastrulation, Invitrogen TBX3 antibody (Invitrogen, 42-4800) was used in chromatin immunoprecipitation on mouse samples (fig 7b). Stem Cell Reports (2013) ncbi
rabbit polyclonal
  • western blot; human; fig 1
In order to identify the TGF-beta1 signaling pathway as a regulator of TBX3 in development and cancer, Invitrogen TBX3 antibody (Zymed, 42-4800) was used in western blot on human samples (fig 1). Mol Biol Cell (2013) ncbi
rabbit polyclonal
  • western blot; human; fig 3
In order to investigate how retinoic acid activates endogenous TBX3 expression, Invitrogen TBX3 antibody (Zymed, 42-4800) was used in western blot on human samples (fig 3). Mol Biol Cell (2012) ncbi
rabbit polyclonal
  • western blot; human; 1:250; fig 1
In order to elucidate the mechanisms regulating TBX3 expression, Invitrogen TBX3 antibody (ZYMED, 42-4800) was used in western blot on human samples at 1:250 (fig 1). Gene (2011) ncbi
rabbit polyclonal
  • western blot; human; 1:250; fig 1
In order to study the regulation of the TBX3 gene, Invitrogen TBX3 antibody (Zymed, 42-4800) was used in western blot on human samples at 1:250 (fig 1). Biochem J (2011) ncbi
Abcam
rabbit polyclonal
  • immunohistochemistry; mouse; 1:100; fig 1e
Abcam TBX3 antibody (Abcam, ab99302) was used in immunohistochemistry on mouse samples at 1:100 (fig 1e). elife (2016) ncbi
Articles Reviewed
  1. Emechebe U, Kumar P P, Rozenberg J, Moore B, Firment A, Mirshahi T, et al. T-box3 is a ciliary protein and regulates stability of the Gli3 transcription factor to control digit number. elife. 2016;5: pubmed publisher
  2. Willmer T, Cooper A, Sims D, Govender D, Prince S. The T-box transcription factor 3 is a promising biomarker and a key regulator of the oncogenic phenotype of a diverse range of sarcoma subtypes. Oncogenesis. 2016;5:e199 pubmed publisher
  3. Li J, Ballim D, Rodriguez M, Cui R, Goding C, Teng H, et al. The anti-proliferative function of the TGF-β1 signaling pathway involves the repression of the oncogenic TBX2 by its homologue TBX3. J Biol Chem. 2014;289:35633-43 pubmed publisher
  4. Weidgang C, Russell R, Tata P, Kühl S, Illing A, Muller M, et al. TBX3 Directs Cell-Fate Decision toward Mesendoderm. Stem Cell Reports. 2013;1:248-65 pubmed publisher
  5. Li J, Weinberg M, Zerbini L, Prince S. The oncogenic TBX3 is a downstream target and mediator of the TGF-?1 signaling pathway. Mol Biol Cell. 2013;24:3569-76 pubmed publisher
  6. Ballim R, Mendelsohn C, Papaioannou V, Prince S. The ulnar-mammary syndrome gene, Tbx3, is a direct target of the retinoic acid signaling pathway, which regulates its expression during mouse limb development. Mol Biol Cell. 2012;23:2362-72 pubmed publisher
  7. Smith J, Mowla S, Prince S. Basal transcription of the human TBX3 gene, a key developmental regulator which is overexpressed in several cancers, requires functional NF-Y and Sp1 sites. Gene. 2011;486:41-6 pubmed publisher
  8. Mowla S, Pinnock R, Leaner V, Goding C, Prince S. PMA-induced up-regulation of TBX3 is mediated by AP-1 and contributes to breast cancer cell migration. Biochem J. 2011;433:145-53 pubmed publisher