This is a Validated Antibody Database (VAD) review about human TACC3, based on 13 published articles (read how Labome selects the articles), using TACC3 antibody in all methods. It is aimed to help Labome visitors find the most suited TACC3 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
TACC3 synonym: ERIC-1; ERIC1; transforming acidic coiled-coil-containing protein 3

Santa Cruz Biotechnology
mouse monoclonal (D-2)
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; tbl s18
Santa Cruz Biotechnology TACC3 antibody (Santa Cruz Biotechnology, sc-48368) was used in immunohistochemistry - paraffin section on human samples at 1:100 (tbl s18). Science (2017) ncbi
mouse monoclonal (E-4)
  • western blot; human; 1:1000; loading ...; fig S6l
In order to report FOSL1 as a common transcriptional signature across mutant KRAS cancers of distinct tissue origin, Santa Cruz Biotechnology TACC3 antibody (Santa Cruz, sc-376900) was used in western blot on human samples at 1:1000 (fig S6l). Nat Commun (2017) ncbi
mouse monoclonal (D-2)
  • western blot; human; loading ...; fig 6a
In order to quantify changes in cytoplasmic and mitochondrial interactomes in response to apoptosis initiation as a function of caspase activity, Santa Cruz Biotechnology TACC3 antibody (Santa Cruz, sc-48368) was used in western blot on human samples (fig 6a). Mol Syst Biol (2017) ncbi
Abcam
rabbit monoclonal (EPR7756)
  • immunocytochemistry; human; loading ...; fig 1d
  • western blot; human; loading ...; fig 1e
Abcam TACC3 antibody (Abcam, ab134154) was used in immunocytochemistry on human samples (fig 1d) and in western blot on human samples (fig 1e). J Biol Chem (2018) ncbi
Cell Signaling Technology
rabbit polyclonal
  • immunocytochemistry; human; 1:200; fig 4
In order to elucidate the spindle proteome that is clathirin-dependent, Cell Signaling Technology TACC3 antibody (Cell signaling, 5645S) was used in immunocytochemistry on human samples at 1:200 (fig 4). Mol Cell Proteomics (2016) ncbi
rabbit monoclonal (D8H10)
  • western blot; chicken; fig 6
Cell Signaling Technology TACC3 antibody (Cell Signaling, 8842) was used in western blot on chicken samples (fig 6). PLoS Genet (2015) ncbi
rabbit monoclonal (D9E4)
  • western blot; human
Cell Signaling Technology TACC3 antibody (Cell Signaling Technology, 8069) was used in western blot on human samples . Cell Death Dis (2014) ncbi
rabbit monoclonal (D8H10)
  • western blot; pig; fig s1
In order to determine meiotic maturation of porcine oocytes and how aurora kinase A is not involved in CPEB1 phosphorylation and cyclin B1 mRNA polyadenylation, Cell Signaling Technology TACC3 antibody (Cell Signaling Technolog, 8842) was used in western blot on pig samples (fig s1). PLoS ONE (2014) ncbi
EMD Millipore
mouse monoclonal
  • immunohistochemistry - paraffin section; human; 1:1000; loading ...
In order to clarify the role of glycoprotein nonmetastatic melanoma protein B in amyotrophic lateral sclerosis, EMD Millipore TACC3 antibody (Millipore, NE1023) was used in immunohistochemistry - paraffin section on human samples at 1:1000. J Neurosci Res (2017) ncbi
mouse monoclonal
  • immunohistochemistry; rat; 1:1000; loading ...; fig 2b
In order to clarify the role of the prefrontal cortex in aggression using a post-weaning social isolation model, EMD Millipore TACC3 antibody (Millipore, NE1023) was used in immunohistochemistry on rat samples at 1:1000 (fig 2b). Brain Struct Funct (2017) ncbi
mouse monoclonal
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig s1a
EMD Millipore TACC3 antibody (Millipore, NE1023) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig s1a). J Clin Invest (2016) ncbi
mouse monoclonal
  • immunohistochemistry - paraffin section; mouse; 1:500; loading ...; fig 4f
In order to test if FTY720 directly alters neuronal function, EMD Millipore TACC3 antibody (Millipore, NE1023) was used in immunohistochemistry - paraffin section on mouse samples at 1:500 (fig 4f). Exp Neurol (2016) ncbi
mouse monoclonal
  • immunocytochemistry; rat; 1:5000
  • immunocytochemistry; mouse; 1:5000; fig 7
EMD Millipore TACC3 antibody (Millipore, NE1023) was used in immunocytochemistry on rat samples at 1:5000 and in immunocytochemistry on mouse samples at 1:5000 (fig 7). Nat Neurosci (2015) ncbi
Articles Reviewed
  1. Zhang Y, Tan L, Yang Q, Li C, Liou Y. The microtubule-associated protein HURP recruits the centrosomal protein TACC3 to regulate K-fiber formation and support chromosome congression. J Biol Chem. 2018;293:15733-15747 pubmed publisher
  2. Uhlen M, Zhang C, Lee S, Sjöstedt E, Fagerberg L, Bidkhori G, et al. A pathology atlas of the human cancer transcriptome. Science. 2017;357: pubmed publisher
  3. Vallejo A, Perurena N, Guruceaga E, Mazur P, Martínez Canarias S, Zandueta C, et al. An integrative approach unveils FOSL1 as an oncogene vulnerability in KRAS-driven lung and pancreatic cancer. Nat Commun. 2017;8:14294 pubmed publisher
  4. Scott N, Rogers L, Prudova A, Brown N, Fortelny N, Overall C, et al. Interactome disassembly during apoptosis occurs independent of caspase cleavage. Mol Syst Biol. 2017;13:906 pubmed publisher
  5. Nagahara Y, Shimazawa M, Ohuchi K, Ito J, Takahashi H, Tsuruma K, et al. GPNMB ameliorates mutant TDP-43-induced motor neuron cell death. J Neurosci Res. 2017;95:1647-1665 pubmed publisher
  6. Biró L, Toth M, Sipos E, Bruzsik B, Tulogdi A, Bendahan S, et al. Structural and functional alterations in the prefrontal cortex after post-weaning social isolation: relationship with species-typical and deviant aggression. Brain Struct Funct. 2017;222:1861-1875 pubmed publisher
  7. Sanges D, Simonte G, Di Vicino U, Romo N, Pinilla I, Nicolas M, et al. Reprogramming Müller glia via in vivo cell fusion regenerates murine photoreceptors. J Clin Invest. 2016;126:3104-16 pubmed publisher
  8. Rao S, Flores Rodriguez N, Page S, Wong C, Robinson P, Chircop M. The Clathrin-dependent Spindle Proteome. Mol Cell Proteomics. 2016;15:2537-53 pubmed publisher
  9. Anastasiadou S, Knöll B. The multiple sclerosis drug fingolimod (FTY720) stimulates neuronal gene expression, axonal growth and regeneration. Exp Neurol. 2016;279:243-260 pubmed publisher
  10. Burgess S, Peset I, Joseph N, Cavazza T, Vernos I, Pfuhl M, et al. Aurora-A-Dependent Control of TACC3 Influences the Rate of Mitotic Spindle Assembly. PLoS Genet. 2015;11:e1005345 pubmed publisher
  11. Haines J, Herbin O, de la Hera B, Vidaurre O, Moy G, Sun Q, et al. Nuclear export inhibitors avert progression in preclinical models of inflammatory demyelination. Nat Neurosci. 2015;18:511-20 pubmed publisher
  12. Ohoka N, Nagai K, Hattori T, Okuhira K, Shibata N, Cho N, et al. Cancer cell death induced by novel small molecules degrading the TACC3 protein via the ubiquitin-proteasome pathway. Cell Death Dis. 2014;5:e1513 pubmed publisher
  13. Komrskova P, Susor A, Malik R, Procházková B, Liskova L, Supolikova J, et al. Aurora kinase A is not involved in CPEB1 phosphorylation and cyclin B1 mRNA polyadenylation during meiotic maturation of porcine oocytes. PLoS ONE. 2014;9:e101222 pubmed publisher