This is a Validated Antibody Database (VAD) review about human Smc1, based on 12 published articles (read how Labome selects the articles), using Smc1 antibody in all methods. It is aimed to help Labome visitors find the most suited Smc1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Smc1 synonym: CDLS2; DXS423E; SB1.8; SMC1; SMC1L1; SMC1alpha; SMCB

Abcam
domestic rabbit monoclonal (EPFHCR37F)
  • western blot; mouse; 1:2000; fig 4
Abcam Smc1 antibody (Abcam, ab133643) was used in western blot on mouse samples at 1:2000 (fig 4). PLoS Genet (2014) ncbi
Cell Signaling Technology
mouse monoclonal (8E6)
  • western blot; mouse; loading ...; fig s7a
Cell Signaling Technology Smc1 antibody (cell signaling, 6892S) was used in western blot on mouse samples (fig s7a). Nature (2019) ncbi
mouse monoclonal (5D11G5)
  • immunohistochemistry; human; loading ...; fig 4c
In order to determine that HPV activates the Fanconi anemia pathway, leading to the accumulation of a key regulatory protein, FANCD2, in large nuclear foci, Cell Signaling Technology Smc1 antibody (Cell Signaling, 4805) was used in immunohistochemistry on human samples (fig 4c). MBio (2017) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; human; loading ...; fig 1a
In order to describe a role for APRIN in homologous recombination, Cell Signaling Technology Smc1 antibody (Cell Signaling, 4029) was used in immunocytochemistry on human samples (fig 1a). Nucleic Acids Res (2016) ncbi
mouse monoclonal (8E6)
  • western blot; human; 1:1000; loading ...; fig 7f
Cell Signaling Technology Smc1 antibody (Cell Signaling, 6892) was used in western blot on human samples at 1:1000 (fig 7f). Aging (Albany NY) (2016) ncbi
mouse monoclonal (5D11G5)
  • immunocytochemistry; mouse; 1:1000; fig s6
  • western blot; mouse; fig s3
Cell Signaling Technology Smc1 antibody (Cell Signaling, 4805) was used in immunocytochemistry on mouse samples at 1:1000 (fig s6) and in western blot on mouse samples (fig s3). Nat Struct Mol Biol (2015) ncbi
mouse monoclonal (5D11G5)
  • immunocytochemistry; human; 1:50; fig 4
  • western blot; human; fig 3
Cell Signaling Technology Smc1 antibody (Cell Signaling, 4805) was used in immunocytochemistry on human samples at 1:50 (fig 4) and in western blot on human samples (fig 3). PLoS Pathog (2015) ncbi
mouse monoclonal (8E6)
  • western blot; human; 1:1000; loading ...; fig 6a
Cell Signaling Technology Smc1 antibody (Cell Signaling, 6892) was used in western blot on human samples at 1:1000 (fig 6a). EMBO J (2014) ncbi
mouse monoclonal (5D11G5)
  • western blot; human
Cell Signaling Technology Smc1 antibody (Cell Signaling, 4805S) was used in western blot on human samples . PLoS ONE (2014) ncbi
mouse monoclonal (5D11G5)
  • western blot; mouse; fig 1d
In order to elucidate how parvovirus minute virus of mice halts the cell cycle, Cell Signaling Technology Smc1 antibody (Cell Signaling, 4805S) was used in western blot on mouse samples (fig 1d). PLoS Pathog (2014) ncbi
EMD Millipore
mouse monoclonal (5D11G5)
  • western blot; human; 1:400
EMD Millipore Smc1 antibody (Millipore, 5D11G5) was used in western blot on human samples at 1:400. DNA Repair (Amst) (2014) ncbi
mouse monoclonal (5D11G5)
  • western blot; human; 1:1000
EMD Millipore Smc1 antibody (Millipore, 5D11G5) was used in western blot on human samples at 1:1000. Oncogene (2014) ncbi
Articles Reviewed
  1. Gronke K, Hernandez P, Zimmermann J, Klose C, Kofoed Branzk M, Guendel F, et al. Interleukin-22 protects intestinal stem cells against genotoxic stress. Nature. 2019;566:249-253 pubmed publisher
  2. Spriggs C, Laimins L. FANCD2 Binds Human Papillomavirus Genomes and Associates with a Distinct Set of DNA Repair Proteins to Regulate Viral Replication. MBio. 2017;8: pubmed publisher
  3. Couturier A, Fleury H, Patenaude A, Bentley V, Rodrigue A, Coulombe Y, et al. Roles for APRIN (PDS5B) in homologous recombination and in ovarian cancer prediction. Nucleic Acids Res. 2016;44:10879-10897 pubmed
  4. He M, Lin Y, Tang Y, Liu Y, Zhou W, Li C, et al. miR-638 suppresses DNA damage repair by targeting SMC1A expression in terminally differentiated cells. Aging (Albany NY). 2016;8:1442-56 pubmed publisher
  5. Hartlerode A, Morgan M, Wu Y, Buis J, Ferguson D. Recruitment and activation of the ATM kinase in the absence of DNA-damage sensors. Nat Struct Mol Biol. 2015;22:736-43 pubmed publisher
  6. Mehta K, Gunasekharan V, Satsuka A, Laimins L. Human papillomaviruses activate and recruit SMC1 cohesin proteins for the differentiation-dependent life cycle through association with CTCF insulators. PLoS Pathog. 2015;11:e1004763 pubmed publisher
  7. Schmidt L, Wiedner M, Velimezi G, Prochazkova J, Owusu M, Bauer S, et al. ATMIN is required for the ATM-mediated signaling and recruitment of 53BP1 to DNA damage sites upon replication stress. DNA Repair (Amst). 2014;24:122-130 pubmed publisher
  8. Sundaramoorthy S, Vázquez Novelle M, Lekomtsev S, Howell M, Petronczki M. Functional genomics identifies a requirement of pre-mRNA splicing factors for sister chromatid cohesion. EMBO J. 2014;33:2623-42 pubmed publisher
  9. Hopkins J, Hwang G, Jacob J, Sapp N, Bedigian R, Oka K, et al. Meiosis-specific cohesin component, Stag3 is essential for maintaining centromere chromatid cohesion, and required for DNA repair and synapsis between homologous chromosomes. PLoS Genet. 2014;10:e1004413 pubmed publisher
  10. Lee J, Guo Z, Myler L, Zheng S, Paull T. Direct activation of ATM by resveratrol under oxidizing conditions. PLoS ONE. 2014;9:e97969 pubmed publisher
  11. Adeyemi R, Pintel D. Parvovirus-induced depletion of cyclin B1 prevents mitotic entry of infected cells. PLoS Pathog. 2014;10:e1003891 pubmed publisher
  12. Penicud K, Behrens A. DMAP1 is an essential regulator of ATM activity and function. Oncogene. 2014;33:525-31 pubmed publisher