This is a Validated Antibody Database (VAD) review about human Smad7, based on 14 published articles (read how Labome selects the articles), using Smad7 antibody in all methods. It is aimed to help Labome visitors find the most suited Smad7 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Smad7 synonym: CRCS3; MADH7; MADH8

Knockout validation
Santa Cruz Biotechnology
mouse monoclonal (Z8-B)
  • western blot knockout validation; mouse; 1:250; loading ...; fig s12f
Santa Cruz Biotechnology Smad7 antibody (Santa Cruz, sc-101152) was used in western blot knockout validation on mouse samples at 1:250 (fig s12f). J Clin Invest (2022) ncbi
Santa Cruz Biotechnology
mouse monoclonal (Z8-B)
  • western blot knockout validation; mouse; 1:250; loading ...; fig s12f
Santa Cruz Biotechnology Smad7 antibody (Santa Cruz, sc-101152) was used in western blot knockout validation on mouse samples at 1:250 (fig s12f). J Clin Invest (2022) ncbi
mouse monoclonal (B-8)
  • immunohistochemistry; human; loading ...; fig 1a
  • western blot; human; loading ...; fig 2c
Santa Cruz Biotechnology Smad7 antibody (Santa Cruz, sc-365846) was used in immunohistochemistry on human samples (fig 1a) and in western blot on human samples (fig 2c). J Cell Mol Med (2021) ncbi
mouse monoclonal (B-8)
  • western blot; human; loading ...; fig 4a
Santa Cruz Biotechnology Smad7 antibody (SantaCruz, sc-365846) was used in western blot on human samples (fig 4a). Mol Vis (2017) ncbi
mouse monoclonal (B-8)
  • western blot; mouse; 1:200; fig 6c
In order to explore the roles of activated portal fibroblasts and myofibroblasts in the pathogenesis of liver fibrosis induced by bile duct ligation, Santa Cruz Biotechnology Smad7 antibody (Santa Cruz, sc-365846) was used in western blot on mouse samples at 1:200 (fig 6c). J Clin Invest (2017) ncbi
mouse monoclonal (Z8-B)
  • western blot; human; fig 5
Santa Cruz Biotechnology Smad7 antibody (Santa Cruz, sc-101152) was used in western blot on human samples (fig 5). Cell Death Dis (2016) ncbi
mouse monoclonal (B-8)
  • western blot; rat; loading ...; fig 5c
Santa Cruz Biotechnology Smad7 antibody (Santa Cruz Biotechnology, sc-365846) was used in western blot on rat samples (fig 5c). Mol Med Rep (2015) ncbi
mouse monoclonal (B-8)
  • western blot; human; loading ...; fig 4c
Santa Cruz Biotechnology Smad7 antibody (Santa Cruz, sc-365846) was used in western blot on human samples (fig 4c). Connect Tissue Res (2015) ncbi
mouse monoclonal (Z8-B)
  • immunohistochemistry - paraffin section; human; 1:200
Santa Cruz Biotechnology Smad7 antibody (Santa Cruz Biotechnology, sc-101152) was used in immunohistochemistry - paraffin section on human samples at 1:200. Tumour Biol (2014) ncbi
R&D Systems
mouse monoclonal (293039)
  • western blot; human; 1:1000; loading ...; fig 5f
R&D Systems Smad7 antibody (R&D systems, MAB2029) was used in western blot on human samples at 1:1000 (fig 5f). Aging (Albany NY) (2021) ncbi
mouse monoclonal (293039)
  • western blot; zebrafish ; 1:1000; loading ...; fig 5c
  • immunohistochemistry; human; loading ...; fig 8c
R&D Systems Smad7 antibody (R&D Systems, MAB2029) was used in western blot on zebrafish samples at 1:1000 (fig 5c) and in immunohistochemistry on human samples (fig 8c). Cancers (Basel) (2021) ncbi
Invitrogen
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:50; loading ...; fig 1a, 1d
Invitrogen Smad7 antibody (Thermo Fsher, 42-0400) was used in immunohistochemistry - paraffin section on mouse samples at 1:50 (fig 1a, 1d). J Clin Invest (2022) ncbi
domestic rabbit polyclonal
In order to determine the functional role of cucurbitacin I using an in vitro model of cardiac hypertrophy, Invitrogen Smad7 antibody (Invitrogen, 42-0400) was used . PLoS ONE (2015) ncbi
Abcam
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 10a
Abcam Smad7 antibody (Abcam, ab216428) was used in western blot on mouse samples at 1:1000 (fig 10a). Biomed Res Int (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 6a
  • western blot; mouse; 1:500; loading ...; fig 2f
Abcam Smad7 antibody (Abcam, ab216428) was used in immunohistochemistry - paraffin section on mouse samples (fig 6a) and in western blot on mouse samples at 1:500 (fig 2f). Cancer Manag Res (2020) ncbi
MilliporeSigma
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; loading ...; fig 1g
MilliporeSigma Smad7 antibody (Atlas, HPA028897) was used in immunohistochemistry - paraffin section on human samples (fig 1g). Cell (2018) ncbi
Articles Reviewed
  1. Humeres C, Shinde A, Hanna A, Alex L, Hern xe1 ndez S, Li R, et al. Smad7 effects on TGF-β and ErbB2 restrain myofibroblast activation and protect from postinfarction heart failure. J Clin Invest. 2022;132: pubmed publisher
  2. Ye Q, Chen H, Ma H, Xiang X, Hu S, Xia C, et al. Xiaoyu Xiezhuo Drink Protects against Ischemia-Reperfusion Acute Kidney Injury in Aged Mice through Inhibiting the TGF-β1/Smad3 and HIF1 Signaling Pathways. Biomed Res Int. 2021;2021:9963732 pubmed publisher
  3. Chung J, Chan M, Tang P, Chan A, Chung J, Meng X, et al. AANG: A natural compound formula for overcoming multidrug resistance via synergistic rebalancing the TGF-β/Smad signalling in hepatocellular carcinoma. J Cell Mol Med. 2021;25:9805-9813 pubmed publisher
  4. Wang Y, Xu Z, Wang X, Zheng J, Peng L, Zhou Y, et al. Extracellular-vesicle containing miRNA-503-5p released by macrophages contributes to atherosclerosis. Aging (Albany NY). 2021;13:12239-12257 pubmed publisher
  5. Lai C, Yeh K, Lin C, Hsieh Y, Lai H, Chen J, et al. MicroRNA-21 Plays Multiple Oncometabolic Roles in the Process of NAFLD-Related Hepatocellular Carcinoma via PI3K/AKT, TGF-β, and STAT3 Signaling. Cancers (Basel). 2021;13: pubmed publisher
  6. Wang X, Jian X, Dou J, Wei Z, Zhao F. Decreasing Microtubule Actin Cross-Linking Factor 1 Inhibits Melanoma Metastasis by Decreasing Epithelial to Mesenchymal Transition. Cancer Manag Res. 2020;12:663-673 pubmed publisher
  7. Kinchen J, Chen H, Parikh K, Antanaviciute A, Jagielowicz M, Fawkner Corbett D, et al. Structural Remodeling of the Human Colonic Mesenchyme in Inflammatory Bowel Disease. Cell. 2018;175:372-386.e17 pubmed publisher
  8. Haque R, Iuvone P, He L, Choi K, Ngo A, Gokhale S, et al. The MicroRNA-21 signaling pathway is involved in prorenin receptor (PRR) -induced VEGF expression in ARPE-19 cells under a hyperglycemic condition. Mol Vis. 2017;23:251-262 pubmed
  9. Koyama Y, Wang P, Liang S, Iwaisako K, Liu X, Xu J, et al. Mesothelin/mucin 16 signaling in activated portal fibroblasts regulates cholestatic liver fibrosis. J Clin Invest. 2017;127:1254-1270 pubmed publisher
  10. Zhuang L, Yang Y, Ma X, Han B, Wang Z, Zhao Q, et al. MicroRNA-92b promotes hepatocellular carcinoma progression by targeting Smad7 and is mediated by long non-coding RNA XIST. Cell Death Dis. 2016;7:e2203 pubmed publisher
  11. Jeong M, Kim S, Kang H, Park K, Park W, Yang S, et al. Cucurbitacin I Attenuates Cardiomyocyte Hypertrophy via Inhibition of Connective Tissue Growth Factor (CCN2) and TGF- β/Smads Signalings. PLoS ONE. 2015;10:e0136236 pubmed publisher
  12. Huang W, Li L, Tian X, Yan J, Yang X, Wang X, et al. Astragalus and Paeoniae radix rubra extract inhibits liver fibrosis by modulating the transforming growth factor‑β/Smad pathway in rats. Mol Med Rep. 2015;11:805-14 pubmed publisher
  13. Zhang X, Ma Y, You T, Tian X, Zhang H, Zhu Q, et al. Roles of TGF-β/Smad signaling pathway in pathogenesis and development of gluteal muscle contracture. Connect Tissue Res. 2015;56:9-17 pubmed publisher
  14. Zhang Y, Yu Z, Xiao Q, Sun X, Zhu Z, Zhang J, et al. Expression of BAMBI and its combination with Smad7 correlates with tumor invasion and poor prognosis in gastric cancer. Tumour Biol. 2014;35:7047-56 pubmed publisher