This is a Validated Antibody Database (VAD) review about human Set1, based on 12 published articles (read how Labome selects the articles), using Set1 antibody in all methods. It is aimed to help Labome visitors find the most suited Set1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Set1 synonym: KMT2F; Set1; Set1A; histone-lysine N-methyltransferase SETD1A; SET domain-containing protein 1A; hSET1A; lysine N-methyltransferase 2F; set1/Ash2 histone methyltransferase complex subunit SET1

Bethyl
rabbit polyclonal
  • western blot; human; loading ...; fig s9c
Bethyl Set1 antibody (Bethyl Laboratories, A300-290A) was used in western blot on human samples (fig s9c). Sci Adv (2017) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 1c
Bethyl Set1 antibody (Bethyl Laboratories, A300-289A) was used in western blot on mouse samples (fig 1c). elife (2017) ncbi
rabbit polyclonal
  • immunoprecipitation; mouse; fig 2
Bethyl Set1 antibody (Bethyl, A300-289A) was used in immunoprecipitation on mouse samples (fig 2). Epigenetics Chromatin (2016) ncbi
rabbit polyclonal
  • chromatin immunoprecipitation; human; fig 6
  • western blot; human; fig 6
Bethyl Set1 antibody (Bethyl, A300-290A) was used in chromatin immunoprecipitation on human samples (fig 6) and in western blot on human samples (fig 6). Sci Rep (2016) ncbi
rabbit polyclonal
In order to develop reagents to study RNA binding proteins, Bethyl Set1 antibody (Bethyl, A300-288A) was used . Mol Cell (2016) ncbi
rabbit polyclonal
  • chromatin immunoprecipitation; human
  • western blot; human; 1:1000
Bethyl Set1 antibody (BETHYL, A300?C289A) was used in chromatin immunoprecipitation on human samples and in western blot on human samples at 1:1000. Nat Commun (2015) ncbi
rabbit polyclonal
  • chromatin immunoprecipitation; rat
  • western blot; rat; fig 4b
Bethyl Set1 antibody (Bethyl Laboratories, A300- 289A) was used in chromatin immunoprecipitation on rat samples and in western blot on rat samples (fig 4b). Biochim Biophys Acta (2015) ncbi
rabbit polyclonal
  • chromatin immunoprecipitation; mouse; fig 5
In order to elucidate the mechanism by which STAT3 controls NF-kapaB signaling in innate immune cells, Bethyl Set1 antibody (Bethyl, A300-289A) was used in chromatin immunoprecipitation on mouse samples (fig 5). Nat Commun (2014) ncbi
rabbit polyclonal
  • chromatin immunoprecipitation; human; fig 5
  • western blot; human; fig 2
Bethyl Set1 antibody (Bethyl Laboratories, A300-289A) was used in chromatin immunoprecipitation on human samples (fig 5) and in western blot on human samples (fig 2). Mol Cancer Res (2015) ncbi
rabbit polyclonal
  • western blot; human
Bethyl Set1 antibody (Bethyl, A300-289A) was used in western blot on human samples . PLoS Pathog (2014) ncbi
Abcam
rabbit polyclonal
  • western blot; mouse; fig 1f
Abcam Set1 antibody (Abcam, ab70378) was used in western blot on mouse samples (fig 1f). Cell (2018) ncbi
rabbit polyclonal
  • chromatin immunoprecipitation; mouse; fig 6
Abcam Set1 antibody (Abcam, ab70378) was used in chromatin immunoprecipitation on mouse samples (fig 6). BMC Biol (2015) ncbi
Articles Reviewed
  1. Hoshii T, Cifani P, Feng Z, Huang C, Koche R, Chen C, et al. A Non-catalytic Function of SETD1A Regulates Cyclin K and the DNA Damage Response. Cell. 2018;172:1007-1021.e17 pubmed publisher
  2. Yuen K, Slaughter B, Gerton J. Condensin II is anchored by TFIIIC and H3K4me3 in the mammalian genome and supports the expression of active dense gene clusters. Sci Adv. 2017;3:e1700191 pubmed publisher
  3. Endoh M, Endo T, Shinga J, Hayashi K, Farcas A, Ma K, et al. PCGF6-PRC1 suppresses premature differentiation of mouse embryonic stem cells by regulating germ cell-related genes. elife. 2017;6: pubmed publisher
  4. Sun J, Zhao Y, McGreal R, Cohen Tayar Y, Rockowitz S, Wilczek C, et al. Pax6 associates with H3K4-specific histone methyltransferases Mll1, Mll2, and Set1a and regulates H3K4 methylation at promoters and enhancers. Epigenetics Chromatin. 2016;9:37 pubmed publisher
  5. Alarcón V, Hernández S, Rubio L, Alvarez F, Flores Y, Varas Godoy M, et al. The enzymes LSD1 and Set1A cooperate with the viral protein HBx to establish an active hepatitis B viral chromatin state. Sci Rep. 2016;6:25901 pubmed publisher
  6. Sundararaman B, Zhan L, Blue S, Stanton R, Elkins K, Olson S, et al. Resources for the Comprehensive Discovery of Functional RNA Elements. Mol Cell. 2016;61:903-13 pubmed publisher
  7. Tajima K, Yae T, Javaid S, Tam O, Comaills V, Morris R, et al. SETD1A modulates cell cycle progression through a miRNA network that regulates p53 target genes. Nat Commun. 2015;6:8257 pubmed publisher
  8. Fan Z, Hao C, Li M, Dai X, Qin H, Li J, et al. MKL1 is an epigenetic modulator of TGF-β induced fibrogenesis. Biochim Biophys Acta. 2015;1849:1219-28 pubmed publisher
  9. Almuzzaini B, Sarshad A, Farrants A, Percipalle P. Nuclear myosin 1 contributes to a chromatin landscape compatible with RNA polymerase II transcription activation. BMC Biol. 2015;13:35 pubmed publisher
  10. Zhang H, Hu H, Greeley N, Jin J, Matthews A, Ohashi E, et al. STAT3 restrains RANK- and TLR4-mediated signalling by suppressing expression of the E2 ubiquitin-conjugating enzyme Ubc13. Nat Commun. 2014;5:5798 pubmed publisher
  11. Salz T, Deng C, Pampo C, Siemann D, Qiu Y, Brown K, et al. Histone Methyltransferase hSETD1A Is a Novel Regulator of Metastasis in Breast Cancer. Mol Cancer Res. 2015;13:461-9 pubmed publisher
  12. Hu J, Yang Y, Turner P, Jain V, McIntyre L, Renne R. LANA binds to multiple active viral and cellular promoters and associates with the H3K4methyltransferase hSET1 complex. PLoS Pathog. 2014;10:e1004240 pubmed publisher