This is a Validated Antibody Database (VAD) review about human SUV39H1, based on 13 published articles (read how Labome selects the articles), using SUV39H1 antibody in all methods. It is aimed to help Labome visitors find the most suited SUV39H1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
SUV39H1 synonym: H3-K9-HMTase 1; KMT1A; MG44; SUV39H; histone-lysine N-methyltransferase SUV39H1; Su(var)3-9 homolog 1; histone H3-K9 methyltransferase 1; histone-lysine N-methyltransferase, H3 lysine-9 specific 1; lysine N-methyltransferase 1A; position-effect variegation 3-9 homolog

Knockout validation
Cell Signaling Technology
rabbit monoclonal (D11B6)
  • western blot knockout validation; mouse; 1:1000; fig s1
Cell Signaling Technology SUV39H1 antibody (Cell signaling, 8729S) was used in western blot knockout validation on mouse samples at 1:1000 (fig s1). elife (2016) ncbi
Abcam
rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 6g
Abcam SUV39H1 antibody (Abcam, Ab155164) was used in western blot on human samples at 1:1000 (fig 6g). Cell Rep (2017) ncbi
mouse monoclonal (44.1)
  • RNA immunoprecipitation; mouse; loading ...; fig 4a, 4b
  • chromatin immunoprecipitation; mouse; fig 5b
  • western blot; mouse; 1:500; loading ...; fig 4a, 4b
Abcam SUV39H1 antibody (Abcam, ab12405) was used in RNA immunoprecipitation on mouse samples (fig 4a, 4b), in chromatin immunoprecipitation on mouse samples (fig 5b) and in western blot on mouse samples at 1:500 (fig 4a, 4b). Nat Commun (2015) ncbi
mouse monoclonal (44.1)
  • chromatin immunoprecipitation; human; fig 5
Abcam SUV39H1 antibody (Abcam, ab12405) was used in chromatin immunoprecipitation on human samples (fig 5). Oncogene (2016) ncbi
mouse monoclonal (44.1)
  • western blot; mouse; fig 2
Abcam SUV39H1 antibody (Abcam, AB12405) was used in western blot on mouse samples (fig 2). Mol Cell Biol (2013) ncbi
mouse monoclonal (44.1)
  • western blot; human
  • western blot; mouse; fig 5
Abcam SUV39H1 antibody (Abcam, ab12405) was used in western blot on human samples and in western blot on mouse samples (fig 5). J Biol Chem (2013) ncbi
Invitrogen
mouse monoclonal (44.1)
  • western blot; mouse; loading ...; fig s20a
Invitrogen SUV39H1 antibody (Thermo Scientific, MA1-25505) was used in western blot on mouse samples (fig s20a). Science (2019) ncbi
Active Motif
mouse monoclonal (MG44)
  • immunocytochemistry; human; 1:200; loading ...; fig s3c
In order to study the role of Repo-Man in interphase, Active Motif SUV39H1 antibody (Active Motif, 39785) was used in immunocytochemistry on human samples at 1:200 (fig s3c). Nat Commun (2017) ncbi
Bethyl
rabbit polyclonal
  • western blot; human; 1:500; loading ...; fig 6c
Bethyl SUV39H1 antibody (Bethyl, A302-127A) was used in western blot on human samples at 1:500 (fig 6c). PLoS ONE (2016) ncbi
Cell Signaling Technology
rabbit monoclonal (D11B6)
  • chromatin immunoprecipitation; human; loading ...; fig s3
Cell Signaling Technology SUV39H1 antibody (Cell Signaling, 8729S) was used in chromatin immunoprecipitation on human samples (fig s3). MBio (2017) ncbi
rabbit monoclonal (D11B6)
  • western blot knockout validation; mouse; 1:1000; fig s1
Cell Signaling Technology SUV39H1 antibody (Cell signaling, 8729S) was used in western blot knockout validation on mouse samples at 1:1000 (fig s1). elife (2016) ncbi
rabbit monoclonal (D11B6)
  • immunocytochemistry; mouse; 1:1000; fig 5,6
In order to protect preimplantation mouse embryos from endogenous retrotransposons by histone chaperone CAF-1 mediating repressive histone modifications, Cell Signaling Technology SUV39H1 antibody (Cell Signaling, 8729) was used in immunocytochemistry on mouse samples at 1:1000 (fig 5,6). Proc Natl Acad Sci U S A (2015) ncbi
rabbit monoclonal (D11B6)
  • western blot; rat; 1:1000; fig 2
Cell Signaling Technology SUV39H1 antibody (Cell Signaling technology, 8729) was used in western blot on rat samples at 1:1000 (fig 2). J Neurosci (2015) ncbi
rabbit monoclonal (D11B6)
  • immunocytochemistry; mouse
Cell Signaling Technology SUV39H1 antibody (Cell Signaling Technology, 8729) was used in immunocytochemistry on mouse samples . Blood (2014) ncbi
Articles Reviewed
  1. Nicetto D, Donahue G, Jain T, Peng T, Sidoli S, Sheng L, et al. H3K9me3-heterochromatin loss at protein-coding genes enables developmental lineage specification. Science. 2019;363:294-297 pubmed publisher
  2. Nguyen K, Das B, Dobrowolski C, Karn J. Multiple Histone Lysine Methyltransferases Are Required for the Establishment and Maintenance of HIV-1 Latency. MBio. 2017;8: pubmed publisher
  3. Li G, Ji T, Chen J, Fu Y, Hou L, Feng Y, et al. CRL4DCAF8 Ubiquitin Ligase Targets Histone H3K79 and Promotes H3K9 Methylation in the Liver. Cell Rep. 2017;18:1499-1511 pubmed publisher
  4. de Castro I, Budzak J, Di Giacinto M, Ligammari L, Gokhan E, Spanos C, et al. Repo-Man/PP1 regulates heterochromatin formation in interphase. Nat Commun. 2017;8:14048 pubmed publisher
  5. Zhang H, Sun L, Wang K, Wu D, Trappio M, Witting C, et al. Loss of H3K9me3 Correlates with ATM Activation and Histone H2AX Phosphorylation Deficiencies in Hutchinson-Gilford Progeria Syndrome. PLoS ONE. 2016;11:e0167454 pubmed publisher
  6. Walter M, Teissandier A, Pérez Palacios R, Bourc his D. An epigenetic switch ensures transposon repression upon dynamic loss of DNA methylation in embryonic stem cells. elife. 2016;5: pubmed publisher
  7. Hatanaka Y, Inoue K, Oikawa M, Kamimura S, Ogonuki N, Kodama E, et al. Histone chaperone CAF-1 mediates repressive histone modifications to protect preimplantation mouse embryos from endogenous retrotransposons. Proc Natl Acad Sci U S A. 2015;112:14641-6 pubmed publisher
  8. Scarola M, Comisso E, Pascolo R, Chiaradia R, Marión R, Schneider C, et al. Epigenetic silencing of Oct4 by a complex containing SUV39H1 and Oct4 pseudogene lncRNA. Nat Commun. 2015;6:7631 pubmed publisher
  9. Park S, Shim J, Park H, Eum D, Park M, Mi Yi J, et al. MacroH2A1 downregulation enhances the stem-like properties of bladder cancer cells by transactivation of Lin28B. Oncogene. 2016;35:1292-301 pubmed publisher
  10. Liu J, Magri L, Zhang F, Marsh N, Albrecht S, Huynh J, et al. Chromatin landscape defined by repressive histone methylation during oligodendrocyte differentiation. J Neurosci. 2015;35:352-65 pubmed publisher
  11. Hattangadi S, Martinez Morilla S, Patterson H, Shi J, Burke K, Avila Figueroa A, et al. Histones to the cytosol: exportin 7 is essential for normal terminal erythroid nuclear maturation. Blood. 2014;124:1931-40 pubmed
  12. Shamma A, Suzuki M, Hayashi N, Kobayashi M, Sasaki N, Nishiuchi T, et al. ATM mediates pRB function to control DNMT1 protein stability and DNA methylation. Mol Cell Biol. 2013;33:3113-24 pubmed publisher
  13. Kera Y, Katoh Y, Ohta M, Matsumoto M, Takano Yamamoto T, Igarashi K. Methionine adenosyltransferase II-dependent histone H3K9 methylation at the COX-2 gene locus. J Biol Chem. 2013;288:13592-601 pubmed publisher