This is a Validated Antibody Database (VAD) review about human SUFU, based on 14 published articles (read how Labome selects the articles), using SUFU antibody in all methods. It is aimed to help Labome visitors find the most suited SUFU antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
SUFU synonym: JBTS32; PRO1280; SUFUH; SUFUXL

Santa Cruz Biotechnology
mouse monoclonal (F-4)
  • immunocytochemistry; mouse; 1:100; loading ...; fig s6-2a
Santa Cruz Biotechnology SUFU antibody (Santa Cruz Biotechnology, sc-137014) was used in immunocytochemistry on mouse samples at 1:100 (fig s6-2a). elife (2020) ncbi
mouse monoclonal (F-4)
  • immunocytochemistry; mouse; 1:100; loading ...; fig 2g
Santa Cruz Biotechnology SUFU antibody (Santa Cruz Biotechnology, sc-137014) was used in immunocytochemistry on mouse samples at 1:100 (fig 2g). PLoS ONE (2017) ncbi
Abcam
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 3c
Abcam SUFU antibody (Abcam, ab28083) was used in western blot on human samples (fig 3c). Science (2020) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (C81H7)
  • western blot; human; loading ...; fig 3a
Cell Signaling Technology SUFU antibody (CST, 2522) was used in western blot on human samples (fig 3a). Cancers (Basel) (2021) ncbi
domestic rabbit monoclonal (C81H7)
  • western blot; mouse; loading ...; fig 4b
Cell Signaling Technology SUFU antibody (CST, 2522) was used in western blot on mouse samples (fig 4b). Oncogene (2018) ncbi
domestic rabbit monoclonal (C54G2)
  • western blot; human; loading ...; fig 5
Cell Signaling Technology SUFU antibody (Cell Signaling, 2520) was used in western blot on human samples (fig 5). Mol Clin Oncol (2016) ncbi
domestic rabbit monoclonal (C81H7)
  • western blot; human; fig 1
Cell Signaling Technology SUFU antibody (Cell Signaling Tech, C81H7) was used in western blot on human samples (fig 1). EMBO J (2016) ncbi
domestic rabbit monoclonal (C81H7)
  • immunoprecipitation; mouse; fig 8f
  • western blot; mouse; fig 4j
Cell Signaling Technology SUFU antibody (Cell signaling, 2522) was used in immunoprecipitation on mouse samples (fig 8f) and in western blot on mouse samples (fig 4j). elife (2016) ncbi
domestic rabbit monoclonal (C81H7)
  • immunoprecipitation; mouse; fig 8
  • western blot; mouse; 1:1000; fig 8
Cell Signaling Technology SUFU antibody (CST, 2522) was used in immunoprecipitation on mouse samples (fig 8) and in western blot on mouse samples at 1:1000 (fig 8). Nat Commun (2016) ncbi
domestic rabbit monoclonal (C81H7)
  • western blot; human; 1:1000; fig s1
Cell Signaling Technology SUFU antibody (Cell Signaling, C8IH7) was used in western blot on human samples at 1:1000 (fig s1). Oncotarget (2016) ncbi
domestic rabbit monoclonal (C54G2)
  • western blot; mouse; fig s3
In order to study Shh signaling during oncogenesis and hindbrain development due to Eya1 phosphate promotion, Cell Signaling Technology SUFU antibody (Cell Signaling, 2520S) was used in western blot on mouse samples (fig s3). Dev Cell (2015) ncbi
domestic rabbit monoclonal (C81H7)
  • western blot; human; fig 3
In order to elucidate the contribution of lncRNA BCAR4 in breast cancer metastasis, Cell Signaling Technology SUFU antibody (CST, 2522) was used in western blot on human samples (fig 3). Cell (2014) ncbi
domestic rabbit monoclonal (C54G2)
  • western blot; human
Cell Signaling Technology SUFU antibody (Cell Signaling Technology, 2520) was used in western blot on human samples . PLoS ONE (2014) ncbi
domestic rabbit monoclonal (C81H7)
  • western blot; human; loading ...; fig 1f
Cell Signaling Technology SUFU antibody (Cell Signaling, 2522S) was used in western blot on human samples (fig 1f). Nature (2014) ncbi
Articles Reviewed
  1. Koeniger A, Brichkina A, Nee I, Dempwolff L, Hupfer A, Galperin I, et al. Activation of Cilia-Independent Hedgehog/GLI1 Signaling as a Novel Concept for Neuroblastoma Therapy. Cancers (Basel). 2021;13: pubmed publisher
  2. Yoshida S, Aoki K, Fujiwara K, Nakakura T, Kawamura A, Yamada K, et al. The novel ciliogenesis regulator DYRK2 governs Hedgehog signaling during mouse embryogenesis. elife. 2020;9: pubmed publisher
  3. Topalian S, Taube J, Pardoll D. Neoadjuvant checkpoint blockade for cancer immunotherapy. Science. 2020;367: pubmed publisher
  4. Lu J, Liu L, Zheng M, Li X, Wu A, Wu Q, et al. MEKK2 and MEKK3 suppress Hedgehog pathway-dependent medulloblastoma by inhibiting GLI1 function. Oncogene. 2018;37:3864-3878 pubmed publisher
  5. Drannik A, MARTIN J, Peterson R, Ma X, Jiang F, Turnbull J. Cerebrospinal fluid from patients with amyotrophic lateral sclerosis inhibits sonic hedgehog function. PLoS ONE. 2017;12:e0171668 pubmed publisher
  6. Galoian K, Luo S, Qureshi A, Patel P, Price R, Morse A, et al. Effect of cytostatic proline rich polypeptide-1 on tumor suppressors of inflammation pathway signaling in chondrosarcoma. Mol Clin Oncol. 2016;5:618-624 pubmed
  7. Raducu M, Fung E, Serres S, Infante P, Barberis A, Fischer R, et al. SCF (Fbxl17) ubiquitylation of Sufu regulates Hedgehog signaling and medulloblastoma development. EMBO J. 2016;35:1400-16 pubmed publisher
  8. Emechebe U, Kumar P P, Rozenberg J, Moore B, Firment A, Mirshahi T, et al. T-box3 is a ciliary protein and regulates stability of the Gli3 transcription factor to control digit number. elife. 2016;5: pubmed publisher
  9. Yan B, Zhang Z, Jin D, Cai C, Jia C, Liu W, et al. mTORC1 regulates PTHrP to coordinate chondrocyte growth, proliferation and differentiation. Nat Commun. 2016;7:11151 pubmed publisher
  10. Di Magno L, Basile A, Coni S, Manni S, Sdruscia G, D Amico D, et al. The energy sensor AMPK regulates Hedgehog signaling in human cells through a unique Gli1 metabolic checkpoint. Oncotarget. 2016;7:9538-49 pubmed publisher
  11. Eisner A, Pazyra Murphy M, Durresi E, Zhou P, Zhao X, Chadwick E, et al. The Eya1 phosphatase promotes Shh signaling during hindbrain development and oncogenesis. Dev Cell. 2015;33:22-35 pubmed publisher
  12. Xing Z, Lin A, Li C, Liang K, Wang S, Liu Y, et al. lncRNA directs cooperative epigenetic regulation downstream of chemokine signals. Cell. 2014;159:1110-1125 pubmed publisher
  13. So J, Lin J, Wahler J, Liby K, Sporn M, Suh N. A synthetic triterpenoid CDDO-Im inhibits tumorsphere formation by regulating stem cell signaling pathways in triple-negative breast cancer. PLoS ONE. 2014;9:e107616 pubmed publisher
  14. Zahreddine H, Culjkovic Kraljacic B, Assouline S, Gendron P, Romeo A, Morris S, et al. The sonic hedgehog factor GLI1 imparts drug resistance through inducible glucuronidation. Nature. 2014;511:90-3 pubmed publisher