This is a Validated Antibody Database (VAD) review about human STRA8, based on 21 published articles (read how Labome selects the articles), using STRA8 antibody in all methods. It is aimed to help Labome visitors find the most suited STRA8 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
STRA8 synonym: stimulated by retinoic acid gene 8 protein homolog; stimulated by retinoic acid 8 homolog; stimulated by retinoic acid gene 8 homolog

Knockout validation
Abcam
rabbit polyclonal
  • immunocytochemistry knockout validation; rabbit; 1:400; fig '2c'
  • western blot knockout validation; rabbit; fig '4c'
Abcam STRA8 antibody (Abcam, ab49602) was used in immunocytochemistry knockout validation on rabbit samples at 1:400 (fig '2c') and in western blot knockout validation on rabbit samples (fig '4c'). Nat Commun (2016) ncbi
Abcam
rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:400; loading ...; fig 3a
Abcam STRA8 antibody (Abcam, Ab49602) was used in immunohistochemistry - paraffin section on mouse samples at 1:400 (fig 3a). Nature (2019) ncbi
rabbit polyclonal
  • western blot; rat; 1:1000; fig 2b
In order to elucidate how particulate matter impairs male reproduction, Abcam STRA8 antibody (Abcam, ab49602) was used in western blot on rat samples at 1:1000 (fig 2b). Toxicol Lett (2017) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:2000; loading ...; fig 4a
In order to test if vitamin A prevents round spermatid nuclear damage and increases motile sperm production, Abcam STRA8 antibody (Abcam, ab49602) was used in immunohistochemistry - paraffin section on mouse samples at 1:2000 (fig 4a). Mol Hum Reprod (2016) ncbi
rabbit polyclonal
  • immunocytochemistry knockout validation; rabbit; 1:400; fig '2c'
  • western blot knockout validation; rabbit; fig '4c'
Abcam STRA8 antibody (Abcam, ab49602) was used in immunocytochemistry knockout validation on rabbit samples at 1:400 (fig '2c') and in western blot knockout validation on rabbit samples (fig '4c'). Nat Commun (2016) ncbi
rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; fig s1
Abcam STRA8 antibody (abcam, Ab49602) was used in immunohistochemistry - frozen section on mouse samples (fig s1). PLoS Genet (2015) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; fig 5
In order to analyze infertility in mice by deletion of the tyrosine phosphatase Shp2 in Sertoli cells, Abcam STRA8 antibody (abcam, ab49405) was used in immunohistochemistry - paraffin section on mouse samples (fig 5). Sci Rep (2015) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:300; fig 7
Abcam STRA8 antibody (Abcam, Ab49602) was used in immunohistochemistry - paraffin section on mouse samples at 1:300 (fig 7). Cell Death Dis (2015) ncbi
rabbit polyclonal
  • immunocytochemistry; mouse; 1:200; loading ...; fig 4a
Abcam STRA8 antibody (Abcam, ab49405) was used in immunocytochemistry on mouse samples at 1:200 (fig 4a). Sci Rep (2015) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse
  • western blot; mouse; fig 5
Abcam STRA8 antibody (abcam, ab49602) was used in immunohistochemistry - paraffin section on mouse samples and in western blot on mouse samples (fig 5). Oncotarget (2015) ncbi
rabbit polyclonal
  • immunohistochemistry; mouse; 1:3000
Abcam STRA8 antibody (Abcam, ab49602) was used in immunohistochemistry on mouse samples at 1:3000. Biol Reprod (2015) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:400; fig 9e
Abcam STRA8 antibody (Abcam, ab49602) was used in immunohistochemistry - paraffin section on mouse samples at 1:400 (fig 9e). Reprod Sci (2015) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; fig 5
Abcam STRA8 antibody (Abcam, ab49405) was used in western blot on mouse samples at 1:1000 (fig 5). Cell Death Dis (2015) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; rat; 1:50
Abcam STRA8 antibody (Abcam, ab49602) was used in immunohistochemistry - paraffin section on rat samples at 1:50. Reprod Toxicol (2015) ncbi
rabbit polyclonal
  • immunohistochemistry; mouse; 1:200
In order to investigate mechanisms by which organs coordinate their size and shape, Abcam STRA8 antibody (Abcam, ab49405) was used in immunohistochemistry on mouse samples at 1:200. Dev Biol (2014) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; scFv
Abcam STRA8 antibody (Abcam, ab49602) was used in immunohistochemistry - paraffin section on scFv samples . Anim Reprod Sci (2014) ncbi
rabbit polyclonal
  • immunocytochemistry; mouse
Abcam STRA8 antibody (Abcam, ab49602) was used in immunocytochemistry on mouse samples . Fertil Steril (2013) ncbi
rabbit polyclonal
  • immunocytochemistry; mouse; 1:10
  • western blot; mouse; 1:1000
Abcam STRA8 antibody (Abcam, Ab49405) was used in immunocytochemistry on mouse samples at 1:10 and in western blot on mouse samples at 1:1000. Biol Reprod (2013) ncbi
rabbit polyclonal
  • western blot; mouse; 1:200
Abcam STRA8 antibody (Abcam, ab49405) was used in western blot on mouse samples at 1:200. Dev Biol (2013) ncbi
rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; 1:500
Abcam STRA8 antibody (Abcam, ab49602) was used in immunohistochemistry - frozen section on mouse samples at 1:500. Reprod Toxicol (2012) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; fig 3
Abcam STRA8 antibody (Abcam, ab49405) was used in immunohistochemistry - paraffin section on mouse samples (fig 3). Epigenetics Chromatin (2012) ncbi
OriGene
rabbit polyclonal
  • immunocytochemistry; human; 1:100; fig 6
In order to describe methods to generate female germline stem cells and characterize these cells, OriGene STRA8 antibody (ORIGENE, TA321988) was used in immunocytochemistry on human samples at 1:100 (fig 6). Sci Rep (2016) ncbi
Articles Reviewed
  1. DiTroia S, Percharde M, Guerquin M, Wall E, Collignon E, Ebata K, et al. Maternal vitamin C regulates reprogramming of DNA methylation and germline development. Nature. 2019;573:271-275 pubmed publisher
  2. Cao X, Shen L, Wu S, Yan C, Zhou Y, Xiong G, et al. Urban fine particulate matter exposure causes male reproductive injury through destroying blood-testis barrier (BTB) integrity. Toxicol Lett. 2017;266:1-12 pubmed publisher
  3. Dumont L, Oblette A, Rondanino C, Jumeau F, Bironneau A, Liot D, et al. Vitamin A prevents round spermatid nuclear damage and promotes the production of motile sperm during in vitro maturation of vitrified pre-pubertal mouse testicular tissue. Mol Hum Reprod. 2016;22:819-832 pubmed
  4. Ding X, Liu G, Xu B, Wu C, Hui N, Ni X, et al. Human GV oocytes generated by mitotically active germ cells obtained from follicular aspirates. Sci Rep. 2016;6:28218 pubmed publisher
  5. Suzuki A, Hirasaki M, Hishida T, Wu J, Okamura D, Ueda A, et al. Loss of MAX results in meiotic entry in mouse embryonic and germline stem cells. Nat Commun. 2016;7:11056 pubmed publisher
  6. Gely Pernot A, Raverdeau M, Teletin M, Vernet N, Féret B, Klopfenstein M, et al. Retinoic Acid Receptors Control Spermatogonia Cell-Fate and Induce Expression of the SALL4A Transcription Factor. PLoS Genet. 2015;11:e1005501 pubmed publisher
  7. Hu X, Tang Z, Li Y, Liu W, Zhang S, Wang B, et al. Deletion of the tyrosine phosphatase Shp2 in Sertoli cells causes infertility in mice. Sci Rep. 2015;5:12982 pubmed publisher
  8. Xu J, Wan P, Wang M, Zhang J, Gao X, Hu B, et al. AIP1-mediated actin disassembly is required for postnatal germ cell migration and spermatogonial stem cell niche establishment. Cell Death Dis. 2015;6:e1818 pubmed publisher
  9. Wang Y, Zhu T, Li Q, Liu C, Han F, Chen M, et al. Prmt5 is required for germ cell survival during spermatogenesis in mice. Sci Rep. 2015;5:11031 pubmed publisher
  10. Ferder I, Wang N. Hypermaintenance and hypofunction of aged spermatogonia: insight from age-related increase of Plzf expression. Oncotarget. 2015;6:15891-901 pubmed
  11. Welborn J, Davis M, Ebers S, Stodden G, Hayashi K, Cheatwood J, et al. Rhox8 Ablation in the Sertoli Cells Using a Tissue-Specific RNAi Approach Results in Impaired Male Fertility in Mice. Biol Reprod. 2015;93:8 pubmed publisher
  12. Sriraman K, Bhartiya D, Anand S, Bhutda S. Mouse Ovarian Very Small Embryonic-Like Stem Cells Resist Chemotherapy and Retain Ability to Initiate Oocyte-Specific Differentiation. Reprod Sci. 2015;22:884-903 pubmed publisher
  13. Tassinari V, Campolo F, Cesarini V, Todaro F, Dolci S, Rossi P. Fgf9 inhibition of meiotic differentiation in spermatogonia is mediated by Erk-dependent activation of Nodal-Smad2/3 signaling and is antagonized by Kit Ligand. Cell Death Dis. 2015;6:e1688 pubmed publisher
  14. Huang S, Cui Y, Guo X, Wang L, Li S, Lu Y, et al. 2,2',4,4'-Tetrabromodiphenyl ether disrupts spermatogenesis, impairs mitochondrial function and induces apoptosis of early leptotene spermatocytes in rats. Reprod Toxicol. 2015;51:114-24 pubmed publisher
  15. Wainwright E, Svingen T, Ng E, Wicking C, Koopman P. Primary cilia function regulates the length of the embryonic trunk axis and urogenital field in mice. Dev Biol. 2014;395:342-54 pubmed publisher
  16. Godoy Pieri N, da Silva Santos P, Santos Roballo K, Flamini M, Barbeito C, Ambrosio C, et al. Seasonal variations cause morphological changes and altered spermatogenesis in the testes of viscacha (Lagostomus maximus). Anim Reprod Sci. 2014;149:316-24 pubmed publisher
  17. Imudia A, Wang N, Tanaka Y, White Y, Woods D, Tilly J. Comparative gene expression profiling of adult mouse ovary-derived oogonial stem cells supports a distinct cellular identity. Fertil Steril. 2013;100:1451-8 pubmed publisher
  18. Tedesco M, Desimio M, Klinger F, De Felici M, Farini D. Minimal concentrations of retinoic acid induce stimulation by retinoic acid 8 and promote entry into meiosis in isolated pregonadal and gonadal mouse primordial germ cells. Biol Reprod. 2013;88:145 pubmed publisher
  19. Gallagher S, Kofman A, Huszar J, Dannenberg J, Depinho R, Braun R, et al. Distinct requirements for Sin3a in perinatal male gonocytes and differentiating spermatogonia. Dev Biol. 2013;373:83-94 pubmed publisher
  20. Aoki T, Takada T. Bisphenol A modulates germ cell differentiation and retinoic acid signaling in mouse ES cells. Reprod Toxicol. 2012;34:463-70 pubmed publisher
  21. Sleutels F, Soochit W, Bartkuhn M, Heath H, Dienstbach S, Bergmaier P, et al. The male germ cell gene regulator CTCFL is functionally different from CTCF and binds CTCF-like consensus sites in a nucleosome composition-dependent manner. Epigenetics Chromatin. 2012;5:8 pubmed publisher