This is a Validated Antibody Database (VAD) review about human STK3, based on 20 published articles (read how Labome selects the articles), using STK3 antibody in all methods. It is aimed to help Labome visitors find the most suited STK3 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
STK3 synonym: KRS1; MST2

Knockout validation
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot knockout validation; human; loading ...; fig 1f
Cell Signaling Technology STK3 antibody (Cell Signaling, 3952) was used in western blot knockout validation on human samples (fig 1f). elife (2020) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot knockout validation; human; loading ...; fig 1i
  • proximity ligation assay; human; 1:100; loading ...; fig 1a
Cell Signaling Technology STK3 antibody (Cell Signaling, 3952s) was used in western blot knockout validation on human samples (fig 1i) and in proximity ligation assay on human samples at 1:100 (fig 1a). J Vis Exp (2018) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot knockout validation; human; loading ...; fig 4b
Cell Signaling Technology STK3 antibody (Cell Signaling, 3952) was used in western blot knockout validation on human samples (fig 4b). J Biol Chem (2016) ncbi
Abcam
domestic rabbit polyclonal
  • western blot; rat; loading ...; fig 2b
Abcam STK3 antibody (Abcam, ab79199) was used in western blot on rat samples (fig 2b). Cell Rep (2021) ncbi
domestic rabbit monoclonal (EP1466Y)
  • western blot; human; 1:1000; loading ...; fig 2a
Abcam STK3 antibody (Abcam, ab52641) was used in western blot on human samples at 1:1000 (fig 2a). J Exp Med (2020) ncbi
domestic rabbit monoclonal (EP1466Y)
  • immunoprecipitation; human; loading ...; fig ev2a
  • western blot; human; loading ...; fig ev2c
Abcam STK3 antibody (Abcam, ab52641) was used in immunoprecipitation on human samples (fig ev2a) and in western blot on human samples (fig ev2c). EMBO J (2019) ncbi
mouse monoclonal (3067C3a)
  • immunocytochemistry; human; loading ...; fig 2b
Abcam STK3 antibody (Abcam, ab71960) was used in immunocytochemistry on human samples (fig 2b). EMBO J (2019) ncbi
domestic rabbit monoclonal (EP1466Y)
  • western blot; human; 1:2000; fig 1
Abcam STK3 antibody (Abcam, ab52641) was used in western blot on human samples at 1:2000 (fig 1). Nat Commun (2015) ncbi
domestic rabbit monoclonal (EP1466Y)
  • immunohistochemistry; mouse; loading ...; fig 5a
  • western blot; mouse; 1:1000; loading ...; fig 6a
Abcam STK3 antibody (Abcam, ab52641) was used in immunohistochemistry on mouse samples (fig 5a) and in western blot on mouse samples at 1:1000 (fig 6a). Biochim Biophys Acta (2015) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (E7U1D)
  • western blot; mouse; 1:1000; loading ...; fig s1b, s3a
Cell Signaling Technology STK3 antibody (CST, 49332) was used in western blot on mouse samples at 1:1000 (fig s1b, s3a). Aging Cell (2021) ncbi
domestic rabbit monoclonal (E7U1D)
  • western blot; human; 1:1000; loading ...; fig 4h
Cell Signaling Technology STK3 antibody (Cell Signaling, 49332) was used in western blot on human samples at 1:1000 (fig 4h). Nat Commun (2021) ncbi
domestic rabbit polyclonal
  • western blot knockout validation; human; loading ...; fig 1f
Cell Signaling Technology STK3 antibody (Cell Signaling, 3952) was used in western blot knockout validation on human samples (fig 1f). elife (2020) ncbi
domestic rabbit monoclonal (E7U1D)
  • western blot; human; loading ...; fig 2b
Cell Signaling Technology STK3 antibody (Cell Signaling, 49332) was used in western blot on human samples (fig 2b). Redox Biol (2020) ncbi
domestic rabbit monoclonal (E7U1D)
  • western blot; human; 1:500; loading ...; fig 3a
Cell Signaling Technology STK3 antibody (Cell Signaling Technology, 49332) was used in western blot on human samples at 1:500 (fig 3a). Cancer Manag Res (2019) ncbi
domestic rabbit polyclonal
  • western blot knockout validation; human; loading ...; fig 1i
  • proximity ligation assay; human; 1:100; loading ...; fig 1a
Cell Signaling Technology STK3 antibody (Cell Signaling, 3952s) was used in western blot knockout validation on human samples (fig 1i) and in proximity ligation assay on human samples at 1:100 (fig 1a). J Vis Exp (2018) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 2c
Cell Signaling Technology STK3 antibody (Cell Signaling, 3952) was used in western blot on human samples (fig 2c). Cancer Res (2017) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig s3I
In order to find that that Fat4 modulates Hippo signaling and restricts hearth growth in mice, Cell Signaling Technology STK3 antibody (Cell signalling, 3952) was used in western blot on mouse samples at 1:1000 (fig s3I). Nat Commun (2017) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 3a
Cell Signaling Technology STK3 antibody (Cell Signaling Technology, 3952) was used in western blot on mouse samples at 1:1000 (fig 3a). Nat Commun (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 4
Cell Signaling Technology STK3 antibody (Cell Signaling, 3952) was used in western blot on human samples (fig 4). Mol Clin Oncol (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; fig 6
  • western blot; human; fig 6
Cell Signaling Technology STK3 antibody (Cell Signaling, 3952) was used in western blot on mouse samples (fig 6) and in western blot on human samples (fig 6). Sci Rep (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 1c
In order to demonstrate that the Hippo, Wnt/beta-catenin, and Notch pathways interact to regulate liver size and inhibit hepatocellular carcinoma, Cell Signaling Technology STK3 antibody (Cell Signaling, 3952) was used in western blot on mouse samples (fig 1c). J Clin Invest (2017) ncbi
domestic rabbit polyclonal
  • western blot knockout validation; human; loading ...; fig 4b
Cell Signaling Technology STK3 antibody (Cell Signaling, 3952) was used in western blot knockout validation on human samples (fig 4b). J Biol Chem (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 4
Cell Signaling Technology STK3 antibody (Cell Signaling, 3952) was used in western blot on human samples (fig 4). Cell Signal (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig s2
In order to study the activation mechanisms of core Hippo pathway components, Cell Signaling Technology STK3 antibody (Cell Signaling Technology, 3952) was used in western blot on human samples (fig s2). EMBO Rep (2016) ncbi
Articles Reviewed
  1. Xu X, Shen X, Wang J, Feng W, Wang M, Miao X, et al. YAP prevents premature senescence of astrocytes and cognitive decline of Alzheimer's disease through regulating CDK6 signaling. Aging Cell. 2021;20:e13465 pubmed publisher
  2. Lupse B, Annamalai K, Ibrahim H, Kaur S, Geravandi S, Sarma B, et al. Inhibition of PHLPP1/2 phosphatases rescues pancreatic β-cells in diabetes. Cell Rep. 2021;36:109490 pubmed publisher
  3. Dai M, Yan G, Wang N, Daliah G, Edick A, Poulet S, et al. In vivo genome-wide CRISPR screen reveals breast cancer vulnerabilities and synergistic mTOR/Hippo targeted combination therapy. Nat Commun. 2021;12:3055 pubmed publisher
  4. Bae S, Ni L, Luo X. STK25 suppresses Hippo signaling by regulating SAV1-STRIPAK antagonism. elife. 2020;9: pubmed publisher
  5. An L, Nie P, Chen M, Tang Y, Zhang H, Guan J, et al. MST4 kinase suppresses gastric tumorigenesis by limiting YAP activation via a non-canonical pathway. J Exp Med. 2020;217: pubmed publisher
  6. Escoll M, Lastra D, Pajares M, Robledinos Antón N, Rojo A, Fernández Ginés R, et al. Transcription factor NRF2 uses the Hippo pathway effector TAZ to induce tumorigenesis in glioblastomas. Redox Biol. 2020;30:101425 pubmed publisher
  7. Chatzifrangkeskou M, Pefani D, Eyres M, Vendrell I, Fischer R, Panková D, et al. RASSF1A is required for the maintenance of nuclear actin levels. EMBO J. 2019;38:e101168 pubmed publisher
  8. Rong X, Han Q, Lin X, Kremerskothen J, Wang E. FRMPD1 activates the Hippo pathway via interaction with WWC3 to suppress the proliferation and invasiveness of lung cancer cells. Cancer Manag Res. 2019;11:3395-3410 pubmed publisher
  9. Karchugina S, Chernoff J. Detection of Heterodimerization of Protein Isoforms Using an in Situ Proximity Ligation Assay. J Vis Exp. 2018;: pubmed publisher
  10. Toloczko A, Guo F, Yuen H, Wen Q, Wood S, Ong Y, et al. Deubiquitinating Enzyme USP9X Suppresses Tumor Growth via LATS Kinase and Core Components of the Hippo Pathway. Cancer Res. 2017;77:4921-4933 pubmed publisher
  11. Ragni C, Diguet N, Le Garrec J, Novotova M, Resende T, Pop S, et al. Amotl1 mediates sequestration of the Hippo effector Yap1 downstream of Fat4 to restrict heart growth. Nat Commun. 2017;8:14582 pubmed publisher
  12. Jerić I, Maurer G, Cavallo A, Raguz J, Desideri E, Tarkowski B, et al. A cell-autonomous tumour suppressor role of RAF1 in hepatocarcinogenesis. Nat Commun. 2016;7:13781 pubmed publisher
  13. Galoian K, Luo S, Qureshi A, Patel P, Price R, Morse A, et al. Effect of cytostatic proline rich polypeptide-1 on tumor suppressors of inflammation pathway signaling in chondrosarcoma. Mol Clin Oncol. 2016;5:618-624 pubmed
  14. Boro M, Singh V, Balaji K. Mycobacterium tuberculosis-triggered Hippo pathway orchestrates CXCL1/2 expression to modulate host immune responses. Sci Rep. 2016;6:37695 pubmed publisher
  15. Kim W, Khan S, Gvozdenovic Jeremic J, Kim Y, Dahlman J, Kim H, et al. Hippo signaling interactions with Wnt/?-catenin and Notch signaling repress liver tumorigenesis. J Clin Invest. 2017;127:137-152 pubmed publisher
  16. Feng X, Liu P, Zhou X, Li M, Li F, Wang Z, et al. Thromboxane A2 Activates YAP/TAZ Protein to Induce Vascular Smooth Muscle Cell Proliferation and Migration. J Biol Chem. 2016;291:18947-58 pubmed publisher
  17. Hoa L, Kulaberoglu Y, Gundogdu R, Cook D, Mavis M, Gomez M, et al. The characterisation of LATS2 kinase regulation in Hippo-YAP signalling. Cell Signal. 2016;28:488-497 pubmed publisher
  18. Kim M, Kim M, Park S, Lee C, Lim D. Role of Angiomotin-like 2 mono-ubiquitination on YAP inhibition. EMBO Rep. 2016;17:64-78 pubmed publisher
  19. Meng Z, Moroishi T, Mottier Pavie V, Plouffe S, Hansen C, Hong A, et al. MAP4K family kinases act in parallel to MST1/2 to activate LATS1/2 in the Hippo pathway. Nat Commun. 2015;6:8357 pubmed publisher
  20. Yang Z, Zheng B, Zhang Y, He M, Zhang X, Ma D, et al. miR-155-dependent regulation of mammalian sterile 20-like kinase 2 (MST2) coordinates inflammation, oxidative stress and proliferation in vascular smooth muscle cells. Biochim Biophys Acta. 2015;1852:1477-89 pubmed publisher