This is a Validated Antibody Database (VAD) review about human STAT6, based on 40 published articles (read how Labome selects the articles), using STAT6 antibody in all methods. It is aimed to help Labome visitors find the most suited STAT6 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
STAT6 synonym: D12S1644; IL-4-STAT; STAT6B; STAT6C

Abcam
domestic rabbit monoclonal (YE361)
  • chromatin immunoprecipitation; human; loading ...; fig 5d
Abcam STAT6 antibody (Abcam, ab32520) was used in chromatin immunoprecipitation on human samples (fig 5d). Front Oncol (2022) ncbi
domestic rabbit monoclonal (YE361)
  • western blot; human; 1:1000; loading ...; fig 2e
Abcam STAT6 antibody (Abcam, ab32520) was used in western blot on human samples at 1:1000 (fig 2e). Aging (Albany NY) (2021) ncbi
domestic rabbit monoclonal (YE361)
  • western blot; mouse; loading ...; fig 7j
  • western blot; human; loading ...; fig 7q
Abcam STAT6 antibody (Abcam, ab32520) was used in western blot on mouse samples (fig 7j) and in western blot on human samples (fig 7q). Signal Transduct Target Ther (2021) ncbi
domestic rabbit monoclonal (YE361)
Abcam STAT6 antibody (Abcam, ab32520) was used . Antioxidants (Basel) (2020) ncbi
domestic rabbit monoclonal (YE361)
  • western blot; human; 1:1000; loading ...; fig 6g
Abcam STAT6 antibody (Abcam, ab32520) was used in western blot on human samples at 1:1000 (fig 6g). Onco Targets Ther (2020) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:500; loading ...; fig 5g
In order to determine that cardiac abundance of the transcription factor GATA4 is high at P1, but becomes strongly reduced at P7 in parallel with loss of regenerative capacity, Abcam STAT6 antibody (Abcam, ab44718) was used in western blot on mouse samples at 1:500 (fig 5g). EMBO Mol Med (2017) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:3000; loading ...; fig 3a
In order to describe how amino acids and Lamtor1 regulate macrophage polarization, Abcam STAT6 antibody (Abcam, ab44718) was used in western blot on mouse samples at 1:3000 (fig 3a). Nat Commun (2016) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human
Abcam STAT6 antibody (Abcam, ab28829) was used in immunohistochemistry - paraffin section on human samples . Respir Res (2016) ncbi
domestic rabbit monoclonal (YE361)
  • western blot; mouse; 1:2000; loading ...; fig 7c
Abcam STAT6 antibody (Abcam, ab32520) was used in western blot on mouse samples at 1:2000 (fig 7c). J Immunol (2016) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; human; 1:20; tbl 2
In order to evaluate the reliance on EBV or NF-kappaB signaling instead of B-cell receptor signaling in regards to complete phenotypic characterization of PTLD, Abcam STAT6 antibody (Abcam, ab28829) was used in immunohistochemistry on human samples at 1:20 (tbl 2). Hematol Oncol (2017) ncbi
domestic rabbit monoclonal (YE361)
  • western blot; mouse; fig 2,3,4,5
Abcam STAT6 antibody (Abcam, ab32520) was used in western blot on mouse samples (fig 2,3,4,5). Cell Res (2015) ncbi
domestic rabbit monoclonal (YE361)
  • immunohistochemistry - paraffin section; human; 1:80
Abcam STAT6 antibody (ABCam, YE361) was used in immunohistochemistry - paraffin section on human samples at 1:80. Diagn Pathol (2014) ncbi
Invitrogen
domestic rabbit recombinant (46H1L12)
  • immunohistochemistry; mouse; loading ...; fig 1a
  • western blot; mouse; 1:100; loading ...; fig 1c
Invitrogen STAT6 antibody (Thermo Fisher Scientific, 700247) was used in immunohistochemistry on mouse samples (fig 1a) and in western blot on mouse samples at 1:100 (fig 1c). Front Immunol (2021) ncbi
mouse monoclonal (CHI2S4N)
  • flow cytometry; human; loading ...; fig 2
Invitrogen STAT6 antibody (Thermo Fisher, CHI2S4N) was used in flow cytometry on human samples (fig 2). AIDS Res Ther (2017) ncbi
Santa Cruz Biotechnology
mouse monoclonal (C-9)
  • western blot; mouse
Santa Cruz Biotechnology STAT6 antibody (Santa Cruz Biotechnology, sc-1689) was used in western blot on mouse samples . J Immunol (2014) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D3H4)
  • western blot; mouse; 1:1000; loading ...; fig 1f
Cell Signaling Technology STAT6 antibody (CST, 5397) was used in western blot on mouse samples at 1:1000 (fig 1f). Front Immunol (2022) ncbi
domestic rabbit polyclonal
  • flow cytometry; mouse; loading ...; fig s2i
Cell Signaling Technology STAT6 antibody (CST, 9361) was used in flow cytometry on mouse samples (fig s2i). Cell Rep (2022) ncbi
domestic rabbit monoclonal (D8S9Y)
  • western blot; mouse; 1:1000; loading ...; fig 1d
Cell Signaling Technology STAT6 antibody (CST, 56554S) was used in western blot on mouse samples at 1:1000 (fig 1d). Nat Commun (2021) ncbi
domestic rabbit monoclonal (D3H4)
  • western blot; mouse; 1:1000; loading ...; fig 1d
Cell Signaling Technology STAT6 antibody (CST, 5397S) was used in western blot on mouse samples at 1:1000 (fig 1d). Nat Commun (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 1a
Cell Signaling Technology STAT6 antibody (Cell Signaling, 9362) was used in western blot on mouse samples at 1:1000 (fig 1a). Skelet Muscle (2021) ncbi
domestic rabbit polyclonal
  • western blot; human
Cell Signaling Technology STAT6 antibody (Cell Signaling Technology, 9361S) was used in western blot on human samples . Acta Neuropathol Commun (2021) ncbi
domestic rabbit monoclonal (D3H4)
  • western blot; human
Cell Signaling Technology STAT6 antibody (Cell Signaling Technology, D3H4) was used in western blot on human samples . Acta Neuropathol Commun (2021) ncbi
domestic rabbit monoclonal (D8S9Y)
  • western blot; human; 1:1000; loading ...; fig 6a
Cell Signaling Technology STAT6 antibody (cell signalling technology, 56554) was used in western blot on human samples at 1:1000 (fig 6a). Nat Commun (2021) ncbi
domestic rabbit monoclonal (D3H4)
  • western blot; human; 1:1000; loading ...; fig 6a
Cell Signaling Technology STAT6 antibody (cell signalling technology, 5397) was used in western blot on human samples at 1:1000 (fig 6a). Nat Commun (2021) ncbi
domestic rabbit monoclonal (D8S9Y)
  • western blot; human; 1:1000; loading ...; fig s1e
Cell Signaling Technology STAT6 antibody (CST, 56554) was used in western blot on human samples at 1:1000 (fig s1e). J Cell Mol Med (2021) ncbi
domestic rabbit monoclonal (D8S9Y)
  • western blot; mouse; loading ...; fig 7j
Cell Signaling Technology STAT6 antibody (CST, 56554) was used in western blot on mouse samples (fig 7j). Signal Transduct Target Ther (2021) ncbi
domestic rabbit monoclonal (D3H4)
  • western blot; mouse; 1:1000; loading ...; fig 2j
Cell Signaling Technology STAT6 antibody (CST, 5397) was used in western blot on mouse samples at 1:1000 (fig 2j). PLoS Biol (2021) ncbi
domestic rabbit monoclonal (D8S9Y)
  • western blot; mouse; 1:1000; loading ...; fig 2j
Cell Signaling Technology STAT6 antibody (CST, 56554) was used in western blot on mouse samples at 1:1000 (fig 2j). PLoS Biol (2021) ncbi
domestic rabbit monoclonal (D8S9Y)
Cell Signaling Technology STAT6 antibody (Cell Signaling Technologies, 56554) was used . Cell Death Discov (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig s7a
Cell Signaling Technology STAT6 antibody (Cell Signaling, 9361) was used in western blot on mouse samples (fig s7a). Adv Sci (Weinh) (2020) ncbi
domestic rabbit monoclonal (D8S9Y)
Cell Signaling Technology STAT6 antibody (Cell Signaling, D8S9Y) was used . Antioxidants (Basel) (2020) ncbi
domestic rabbit monoclonal (D3H4)
  • western blot; human; loading ...; fig 3c
Cell Signaling Technology STAT6 antibody (Cell Signaling, 5397) was used in western blot on human samples (fig 3c). Arthritis Res Ther (2020) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 6g
Cell Signaling Technology STAT6 antibody (Cell Signaling, 9361T) was used in western blot on human samples at 1:1000 (fig 6g). Onco Targets Ther (2020) ncbi
domestic rabbit monoclonal (D3H4)
  • western blot; mouse; loading ...; fig e6d
Cell Signaling Technology STAT6 antibody (Cell Signaling Technology, 5397) was used in western blot on mouse samples (fig e6d). Nature (2019) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig e6d
Cell Signaling Technology STAT6 antibody (Cell Signaling Technology, 9361) was used in western blot on mouse samples (fig e6d). Nature (2019) ncbi
domestic rabbit monoclonal (D3H4)
  • western blot; mouse; loading ...; fig 2b
Cell Signaling Technology STAT6 antibody (Cell Signaling, 5397) was used in western blot on mouse samples (fig 2b). Sci Adv (2019) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 1d
Cell Signaling Technology STAT6 antibody (Cell Signaling Technology, 9361S) was used in western blot on mouse samples (fig 1d). Immunity (2018) ncbi
domestic rabbit monoclonal (D3H4)
  • western blot; mouse; 1:1000; loading ...; fig 2a
Cell Signaling Technology STAT6 antibody (Cell Signaling, D3H4) was used in western blot on mouse samples at 1:1000 (fig 2a). Mol Biol Cell (2018) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 7a
Cell Signaling Technology STAT6 antibody (Cell Signaling, 9362) was used in western blot on mouse samples (fig 7a). Cancer Res (2018) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 7a
Cell Signaling Technology STAT6 antibody (Cell Signaling, 9361) was used in western blot on mouse samples (fig 7a). Cancer Res (2018) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig s11a
Cell Signaling Technology STAT6 antibody (Cell Signaling, 9361S) was used in western blot on mouse samples (fig s11a). J Clin Invest (2018) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig s11a
Cell Signaling Technology STAT6 antibody (Cell Signaling, 9362) was used in western blot on mouse samples (fig s11a). J Clin Invest (2018) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 3a
In order to show that the MEK1/2 pathway is a key regulator of macrophage reparative properties, Cell Signaling Technology STAT6 antibody (Cell Signaling, 9362) was used in western blot on mouse samples (fig 3a). J Immunol (2017) ncbi
domestic rabbit monoclonal (D3H4)
  • other; human; loading ...; fig 3
Cell Signaling Technology STAT6 antibody (Cell Signaling Technology, 5397) was used in other on human samples (fig 3). Sci Rep (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; fig 1
Cell Signaling Technology STAT6 antibody (Cell signaling, 9361) was used in western blot on mouse samples at 1:1000 (fig 1). Nat Commun (2016) ncbi
domestic rabbit monoclonal (C11A12)
  • western blot; human
Cell Signaling Technology STAT6 antibody (Cell Signaling, C11A12) was used in western blot on human samples . Mucosal Immunol (2015) ncbi
BD Biosciences
mouse monoclonal (18/P-Stat6)
  • flow cytometry; mouse; 1:50; loading ...; fig 1g
BD Biosciences STAT6 antibody (BD Biosciences, 612601) was used in flow cytometry on mouse samples at 1:50 (fig 1g). Science (2018) ncbi
mouse monoclonal (18/P-Stat6)
  • flow cytometry; mouse; fig 5d
In order to study the involvement of RANKL in decidual M2 macrophage polarization, BD Biosciences STAT6 antibody (BD Biosciences, 612600) was used in flow cytometry on mouse samples (fig 5d). Cell Death Dis (2017) ncbi
mouse monoclonal (18/P-Stat6)
  • flow cytometry; mouse; fig S1
BD Biosciences STAT6 antibody (BD Biosciences, 18/pStat6) was used in flow cytometry on mouse samples (fig S1). Nat Commun (2016) ncbi
mouse monoclonal (18/P-Stat6)
  • western blot; human; loading ...; fig 5d
In order to investigate the contribution of surfactant protein D to asthma, BD Biosciences STAT6 antibody (BD Biosciences, 611566) was used in western blot on human samples (fig 5d). Respir Res (2015) ncbi
mouse monoclonal (23/Stat6)
  • western blot; human; loading ...; fig 5d
In order to investigate the contribution of surfactant protein D to asthma, BD Biosciences STAT6 antibody (BD Biosciences, 611290) was used in western blot on human samples (fig 5d). Respir Res (2015) ncbi
Articles Reviewed
  1. Yu L, Wang L, Hu G, Ren L, Qiu C, Li S, et al. Reprogramming alternative macrophage polarization by GATM-mediated endogenous creatine synthesis: A potential target for HDM-induced asthma treatment. Front Immunol. 2022;13:937331 pubmed publisher
  2. Gao P, Ren G, Liang J, Liu J. STAT6 Upregulates NRP1 Expression in Endothelial Cells and Promotes Angiogenesis. Front Oncol. 2022;12:823377 pubmed publisher
  3. Cortes J, Filip I, Albero R, Patiño Galindo J, Quinn S, Lin W, et al. Oncogenic Vav1-Myo1f induces therapeutically targetable macrophage-rich tumor microenvironment in peripheral T cell lymphoma. Cell Rep. 2022;39:110695 pubmed publisher
  4. Jiao B, An C, Tran M, Du H, Wang P, Zhou D, et al. Pharmacological Inhibition of STAT6 Ameliorates Myeloid Fibroblast Activation and Alternative Macrophage Polarization in Renal Fibrosis. Front Immunol. 2021;12:735014 pubmed publisher
  5. Liu W, Long Q, Zhang W, Zeng D, Hu B, Liu S, et al. miRNA-221-3p derived from M2-polarized tumor-associated macrophage exosomes aggravates the growth and metastasis of osteosarcoma through SOCS3/JAK2/STAT3 axis. Aging (Albany NY). 2021;13:19760-19775 pubmed publisher
  6. Atcha H, Jairaman A, Holt J, Meli V, Nagalla R, Veerasubramanian P, et al. Mechanically activated ion channel Piezo1 modulates macrophage polarization and stiffness sensing. Nat Commun. 2021;12:3256 pubmed publisher
  7. Kurosaka M, Ogura Y, Sato S, Kohda K, Funabashi T. Transcription factor signal transducer and activator of transcription 6 (STAT6) is an inhibitory factor for adult myogenesis. Skelet Muscle. 2021;11:14 pubmed publisher
  8. Lian X, Kats D, Rasmussen S, Martin L, Karki A, Keller C, et al. Design considerations of an IL13Rα2 antibody-drug conjugate for diffuse intrinsic pontine glioma. Acta Neuropathol Commun. 2021;9:88 pubmed publisher
  9. Luo L, Zhang Z, Qiu N, Ling L, Jia X, Song Y, et al. Disruption of FOXO3a-miRNA feedback inhibition of IGF2/IGF-1R/IRS1 signaling confers Herceptin resistance in HER2-positive breast cancer. Nat Commun. 2021;12:2699 pubmed publisher
  10. Hu J, Wang J, Li C, Shang Y. Fructose-1,6-bisphosphatase aggravates oxidative stress-induced apoptosis in asthma by suppressing the Nrf2 pathway. J Cell Mol Med. 2021;25:5001-5014 pubmed publisher
  11. Shen T, Liu J, Wang C, Rixiati Y, Li S, Cai L, et al. Targeting Erbin in B cells for therapy of lung metastasis of colorectal cancer. Signal Transduct Target Ther. 2021;6:115 pubmed publisher
  12. Sripada A, Sirohi K, Michalec L, Guo L, McKay J, Yadav S, et al. Sprouty2 positively regulates T cell function and airway inflammation through regulation of CSK and LCK kinases. PLoS Biol. 2021;19:e3001063 pubmed publisher
  13. Lee J, Park I, Kwak M, Rhee W, Kim S, Shin J. HMGB1 orchestrates STING-mediated senescence via TRIM30α modulation in cancer cells. Cell Death Discov. 2021;7:28 pubmed publisher
  14. Zhang D, Liu C, Li H, Jiao J. Deficiency of STING Signaling in Embryonic Cerebral Cortex Leads to Neurogenic Abnormalities and Autistic-Like Behaviors. Adv Sci (Weinh). 2020;7:2002117 pubmed publisher
  15. Lee H, Park J, Yoo H, Lee H, Lee B, Kim J. The Selenoprotein MsrB1 Instructs Dendritic Cells to Induce T-Helper 1 Immune Responses. Antioxidants (Basel). 2020;9: pubmed publisher
  16. Yang X, Guo Q, Feng T, Lu Q, Ge L, Pan J, et al. IL13Rα1 protects against rheumatoid arthritis by combating the apoptotic resistance of fibroblast-like synoviocytes. Arthritis Res Ther. 2020;22:184 pubmed publisher
  17. Zhu C, Chen X, Guan G, Zou C, Guo Q, Cheng P, et al. IFI30 Is a Novel Immune-Related Target with Predicting Value of Prognosis and Treatment Response in Glioblastoma. Onco Targets Ther. 2020;13:1129-1143 pubmed publisher
  18. Mahmoudi S, Mancini E, Xu L, Moore A, Jahanbani F, Hebestreit K, et al. Heterogeneity in old fibroblasts is linked to variability in reprogramming and wound healing. Nature. 2019;574:553-558 pubmed publisher
  19. Huang X, Feng Z, Jiang Y, Li J, Xiang Q, Guo S, et al. VSIG4 mediates transcriptional inhibition of Nlrp3 and Il-1β in macrophages. Sci Adv. 2019;5:eaau7426 pubmed publisher
  20. Sanin D, Matsushita M, Klein Geltink R, Grzes K, van Teijlingen Bakker N, Corrado M, et al. Mitochondrial Membrane Potential Regulates Nuclear Gene Expression in Macrophages Exposed to Prostaglandin E2. Immunity. 2018;49:1021-1033.e6 pubmed publisher
  21. Li R, Serrano J, Xing H, Lee T, Azizgolshani H, Zaman M, et al. Interstitial flow promotes macrophage polarization toward an M2 phenotype. Mol Biol Cell. 2018;29:1927-1940 pubmed publisher
  22. Tan B, Shi X, Zhang J, Qin J, Zhang N, Ren H, et al. Inhibition of Rspo-Lgr4 Facilitates Checkpoint Blockade Therapy by Switching Macrophage Polarization. Cancer Res. 2018;78:4929-4942 pubmed publisher
  23. Ubil E, Caskey L, Holtzhausen A, Hunter D, Story C, Earp H. Tumor-secreted Pros1 inhibits macrophage M1 polarization to reduce antitumor immune response. J Clin Invest. 2018;128:2356-2369 pubmed publisher
  24. Sockolosky J, Trotta E, Parisi G, Picton L, Su L, Le A, et al. Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes. Science. 2018;359:1037-1042 pubmed publisher
  25. Meng Y, Zhou W, Jin L, Liu L, Chang K, Mei J, et al. RANKL-mediated harmonious dialogue between fetus and mother guarantees smooth gestation by inducing decidual M2 macrophage polarization. Cell Death Dis. 2017;8:e3105 pubmed publisher
  26. Zhao G, Liu L, Su B, Zhang T, Chen P, Li W, et al. The dynamic changes of interferon lambdas related genes and proteins in JAK/STAT pathway in both acute and chronic HIV-1 infected patients. AIDS Res Ther. 2017;14:31 pubmed publisher
  27. Malek Mohammadi M, Kattih B, Grund A, Froese N, Korf Klingebiel M, Gigina A, et al. The transcription factor GATA4 promotes myocardial regeneration in neonatal mice. EMBO Mol Med. 2017;9:265-279 pubmed publisher
  28. Long M, Eddy W, Gong K, Lovelace Macon L, McMahan R, Charron J, et al. MEK1/2 Inhibition Promotes Macrophage Reparative Properties. J Immunol. 2017;198:862-872 pubmed publisher
  29. Yamauchi S, Takeuchi K, Chihara K, Honjoh C, Kato Y, Yoshiki H, et al. STAT1 is essential for the inhibition of hepatitis C virus replication by interferon-λ but not by interferon-α. Sci Rep. 2016;6:38336 pubmed publisher
  30. Kimura T, Nada S, Takegahara N, Okuno T, Nojima S, Kang S, et al. Polarization of M2 macrophages requires Lamtor1 that integrates cytokine and amino-acid signals. Nat Commun. 2016;7:13130 pubmed publisher
  31. Southworth T, Plumb J, Gupta V, Pearson J, Ramis I, Lehner M, et al. Anti-inflammatory potential of PI3K? and JAK inhibitors in asthma patients. Respir Res. 2016;17:124 pubmed
  32. Coppo M, Chinenov Y, Sacta M, Rogatsky I. The transcriptional coregulator GRIP1 controls macrophage polarization and metabolic homeostasis. Nat Commun. 2016;7:12254 pubmed publisher
  33. Al Sadoun H, Burgess M, Hentges K, Mace K. Enforced Expression of Hoxa3 Inhibits Classical and Promotes Alternative Activation of Macrophages In Vitro and In Vivo. J Immunol. 2016;197:872-84 pubmed publisher
  34. Gomez Rodriguez J, Meylan F, Handon R, Hayes E, Anderson S, Kirby M, et al. Itk is required for Th9 differentiation via TCR-mediated induction of IL-2 and IRF4. Nat Commun. 2016;7:10857 pubmed publisher
  35. Menter T, Dickenmann M, Juskevicius D, Steiger J, Dirnhofer S, Tzankov A. Comprehensive phenotypic characterization of PTLD reveals potential reliance on EBV or NF-κB signalling instead of B-cell receptor signalling. Hematol Oncol. 2017;35:187-197 pubmed publisher
  36. Zhang W, Zheng X, Du L, Sun J, Shen Z, Shi C, et al. High salt primes a specific activation state of macrophages, M(Na). Cell Res. 2015;25:893-910 pubmed publisher
  37. Xu J, Singhera G, Dorscheid D. Expression of surfactant protein D in airways of asthmatics and interleukin-13 modulation of surfactant protein D in human models of airway epithelium. Respir Res. 2015;16:26 pubmed publisher
  38. Vogels R, Vlenterie M, Versleijen Jonkers Y, Ruijter E, Bekers E, Verdijk M, et al. Solitary fibrous tumor - clinicopathologic, immunohistochemical and molecular analysis of 28 cases. Diagn Pathol. 2014;9:224 pubmed publisher
  39. Rochman M, Kartashov A, Caldwell J, Collins M, Stucke E, Kc K, et al. Neurotrophic tyrosine kinase receptor 1 is a direct transcriptional and epigenetic target of IL-13 involved in allergic inflammation. Mucosal Immunol. 2015;8:785-98 pubmed publisher
  40. Carlson T, Pellerin A, Djuretic I, Trivigno C, Koralov S, Rao A, et al. Halofuginone-induced amino acid starvation regulates Stat3-dependent Th17 effector function and reduces established autoimmune inflammation. J Immunol. 2014;192:2167-76 pubmed publisher