This is a Validated Antibody Database (VAD) review about human STAT2, based on 27 published articles (read how Labome selects the articles), using STAT2 antibody in all methods. It is aimed to help Labome visitors find the most suited STAT2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
STAT2 synonym: IMD44; ISGF-3; P113; STAT113; signal transducer and activator of transcription 2; interferon alpha induced transcriptional activator; signal transducer and activator of transcription 2, 113kDa

R&D Systems
rabbit monoclonal (1021D)
  • western blot; human; 1:500; loading ...; fig 8
R&D Systems STAT2 antibody (R&D Systems, MAB2890) was used in western blot on human samples at 1:500 (fig 8). J Virol (2019) ncbi
mouse monoclonal (545117)
  • western blot; human; 1:1000; loading ...; fig 8
R&D Systems STAT2 antibody (R&D Systems, MAB1666) was used in western blot on human samples at 1:1000 (fig 8). J Virol (2019) ncbi
rabbit polyclonal
  • flow cytometry; human; loading ...; fig 1
R&D Systems STAT2 antibody (R&D, IC2890F) was used in flow cytometry on human samples (fig 1). PLoS ONE (2017) ncbi
Abcam
rabbit polyclonal
  • western blot; human; loading ...; fig 7b
Abcam STAT2 antibody (Abcam, ab53132) was used in western blot on human samples (fig 7b). Cell Physiol Biochem (2018) ncbi
rabbit monoclonal (Y141)
  • western blot; human; loading ...; fig 7b
Abcam STAT2 antibody (Abcam, ab32367) was used in western blot on human samples (fig 7b). Cell Physiol Biochem (2018) ncbi
rabbit polyclonal
  • western blot; mouse
Abcam STAT2 antibody (Abcam, ab53132) was used in western blot on mouse samples . Virus Res (2014) ncbi
rabbit polyclonal
  • immunohistochemistry; mouse
Abcam STAT2 antibody (Abcam, ab53132) was used in immunohistochemistry on mouse samples . Cancer Res (2013) ncbi
Santa Cruz Biotechnology
mouse monoclonal (A-9)
  • western blot; human; fig 4
Santa Cruz Biotechnology STAT2 antibody (Santa Cruz Biotechnology, A-9) was used in western blot on human samples (fig 4). PLoS Genet (2016) ncbi
mouse monoclonal (A-9)
  • EMSA; human
  • western blot; human
Santa Cruz Biotechnology STAT2 antibody (Santa Cruz Biotechnology, sc-166201) was used in EMSA on human samples and in western blot on human samples . Int J Cancer (2015) ncbi
mouse monoclonal (A-7)
  • western blot; human
Santa Cruz Biotechnology STAT2 antibody (Santa Cruz Biotechnology, sc-1668) was used in western blot on human samples . Viral Immunol (2014) ncbi
Abnova
mouse monoclonal (5G7)
  • other; human; loading ...; fig st1
In order to use size exclusion chromatography-microsphere-based affinity proteomics to study clinical samples obtained from pediatric acute leukemia patients, Abnova STAT2 antibody (Abnova, H00006773-M01) was used in other on human samples (fig st1). Mol Cell Proteomics (2016) ncbi
Cell Signaling Technology
rabbit polyclonal
  • chromatin immunoprecipitation; human; loading ...; fig s1l
Cell Signaling Technology STAT2 antibody (Cell Signaling Technology, 4594S) was used in chromatin immunoprecipitation on human samples (fig s1l). Nature (2019) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; human; loading ...; fig 1d
  • western blot; human; loading ...; fig 4a
Cell Signaling Technology STAT2 antibody (Cell Signaling, 4441) was used in immunohistochemistry - paraffin section on human samples (fig 1d) and in western blot on human samples (fig 4a). Ann Rheum Dis (2018) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 4a
Cell Signaling Technology STAT2 antibody (Cell Signaling, 4594) was used in western blot on human samples (fig 4a). Ann Rheum Dis (2018) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 3a
Cell Signaling Technology STAT2 antibody (Cell Signaling, 4594) was used in western blot on human samples at 1:1000 (fig 3a). Nat Commun (2016) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 1e
Cell Signaling Technology STAT2 antibody (Cell Signaling, 4441) was used in western blot on human samples (fig 1e). J Biol Chem (2014) ncbi
rabbit polyclonal
  • western blot; human; fig 4
Cell Signaling Technology STAT2 antibody (Cell Signaling Technology, #4594) was used in western blot on human samples (fig 4). Liver Int (2014) ncbi
EMD Millipore
rabbit polyclonal
  • western blot; mouse; loading ...; fig s4f
EMD Millipore STAT2 antibody (Millipore, 07-224) was used in western blot on mouse samples (fig s4f). Science (2019) ncbi
rabbit polyclonal
  • western blot; human; 1:2000; loading ...; fig 3a
EMD Millipore STAT2 antibody (Millipore, 07-224) was used in western blot on human samples at 1:2000 (fig 3a). Nat Commun (2016) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 3h
EMD Millipore STAT2 antibody (EMD Millipore, 07-224) was used in western blot on human samples (fig 3h). J Exp Med (2016) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; fig 4
In order to study increased viral resistance in humans and not mice by ISG15 deficiency, EMD Millipore STAT2 antibody (Millipore, 07224) was used in western blot on mouse samples at 1:1000 (fig 4). Nat Commun (2016) ncbi
rabbit polyclonal
  • chromatin immunoprecipitation; human
EMD Millipore STAT2 antibody (upstate, 06-502) was used in chromatin immunoprecipitation on human samples . Cell Biosci (2015) ncbi
rabbit polyclonal
  • western blot; mouse
EMD Millipore STAT2 antibody (Upstate, 07-224) was used in western blot on mouse samples . Mol Cell Biol (2015) ncbi
rabbit polyclonal
  • western blot; human
EMD Millipore STAT2 antibody (Merck Millipore, 07-224) was used in western blot on human samples . Int J Cancer (2015) ncbi
rabbit polyclonal
  • western blot; human
EMD Millipore STAT2 antibody (Millipore, 07-224) was used in western blot on human samples . J Immunol (2014) ncbi
rabbit polyclonal
  • western blot; human
In order to study the effect of bluetongue virus on type I interferon response, EMD Millipore STAT2 antibody (Millipore, 07-224) was used in western blot on human samples . J Virol (2014) ncbi
rabbit polyclonal
  • western blot; human
EMD Millipore STAT2 antibody (Upstate Biotechnology, 07-224) was used in western blot on human samples . Nucleic Acids Res (2014) ncbi
rabbit polyclonal
  • western blot; human; 1:500
EMD Millipore STAT2 antibody (Millipore, 07-224) was used in western blot on human samples at 1:500. Cell Death Dis (2014) ncbi
rabbit polyclonal
  • western blot; mouse; 1:3000
EMD Millipore STAT2 antibody (Millipore, 07-224) was used in western blot on mouse samples at 1:3000. J Virol (2014) ncbi
rabbit polyclonal
  • western blot; human
EMD Millipore STAT2 antibody (Millipore, 07-224) was used in western blot on human samples . J Leukoc Biol (2013) ncbi
rabbit polyclonal
  • western blot; human
EMD Millipore STAT2 antibody (Millipore, 07-224) was used in western blot on human samples . J Biol Chem (2013) ncbi
BD Biosciences
mouse monoclonal (22/Stat2)
  • western blot; human
BD Biosciences STAT2 antibody (BD Biosciences, 610188) was used in western blot on human samples . J Immunol (2014) ncbi
mouse monoclonal (22/Stat2)
  • EMSA; rat; 1 ug
BD Biosciences STAT2 antibody (BD Transduction Laboratories, 610187) was used in EMSA on rat samples at 1 ug. Mol Cancer Ther (2013) ncbi
Articles Reviewed
  1. Liu Y, You Y, Lu Z, Yang J, Li P, Liu L, et al. N6-methyladenosine RNA modification-mediated cellular metabolism rewiring inhibits viral replication. Science. 2019;365:1171-1176 pubmed publisher
  2. De Cecco M, Ito T, Petrashen A, Elias A, Skvir N, Criscione S, et al. L1 drives IFN in senescent cells and promotes age-associated inflammation. Nature. 2019;566:73-78 pubmed publisher
  3. Bressy C, Droby G, Maldonado B, Steuerwald N, Grdzelishvili V. Cell Cycle Arrest in G2/M Phase Enhances Replication of Interferon-Sensitive Cytoplasmic RNA Viruses via Inhibition of Antiviral Gene Expression. J Virol. 2019;93: pubmed publisher
  4. Yin D, Li Y, Fu C, Feng Y. Pro-Angiogenic Role of LncRNA HULC in Microvascular Endothelial Cells via Sequestrating miR-124. Cell Physiol Biochem. 2018;50:2188-2202 pubmed publisher
  5. Sarkar M, Hile G, Tsoi L, Xing X, Liu J, Liang Y, et al. Photosensitivity and type I IFN responses in cutaneous lupus are driven by epidermal-derived interferon kappa. Ann Rheum Dis. 2018;77:1653-1664 pubmed publisher
  6. Hurtado Guerrero I, Pinto Medel M, Urbaneja P, Rodriguez Bada J, Leon A, Guerrero M, et al. Activation of the JAK-STAT Signaling Pathway after In Vitro Stimulation with IFNß in Multiple Sclerosis Patients According to the Therapeutic Response to IFNß. PLoS ONE. 2017;12:e0170031 pubmed publisher
  7. Eletto D, Burns S, Angulo I, Plagnol V, Gilmour K, Henriquez F, et al. Biallelic JAK1 mutations in immunodeficient patient with mycobacterial infection. Nat Commun. 2016;7:13992 pubmed publisher
  8. Baron L, Paatero A, Morel J, Impens F, Guenin Macé L, Saint Auret S, et al. Mycolactone subverts immunity by selectively blocking the Sec61 translocon. J Exp Med. 2016;213:2885-2896 pubmed
  9. Speer S, Li Z, Buta S, Payelle Brogard B, Qian L, Vigant F, et al. ISG15 deficiency and increased viral resistance in humans but not mice. Nat Commun. 2016;7:11496 pubmed publisher
  10. Kim J, He X, Orr B, Wutz G, Hill V, Peters J, et al. Intact Cohesion, Anaphase, and Chromosome Segregation in Human Cells Harboring Tumor-Derived Mutations in STAG2. PLoS Genet. 2016;12:e1005865 pubmed publisher
  11. Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
  12. Ren G, Cui K, Zhang Z, Zhao K. Division of labor between IRF1 and IRF2 in regulating different stages of transcriptional activation in cellular antiviral activities. Cell Biosci. 2015;5:17 pubmed publisher
  13. Wiesauer I, Gaumannmüller C, Steinparzer I, Strobl B, Kovarik P. Promoter occupancy of STAT1 in interferon responses is regulated by processive transcription. Mol Cell Biol. 2015;35:716-27 pubmed publisher
  14. Kolosenko I, Fryknäs M, Forsberg S, Johnsson P, Cheon H, Holvey Bates E, et al. Cell crowding induces interferon regulatory factor 9, which confers resistance to chemotherapeutic drugs. Int J Cancer. 2015;136:E51-61 pubmed publisher
  15. Donlin L, Jayatilleke A, Giannopoulou E, Kalliolias G, Ivashkiv L. Modulation of TNF-induced macrophage polarization by synovial fibroblasts. J Immunol. 2014;193:2373-83 pubmed publisher
  16. Maeda S, Wada H, Naito Y, Nagano H, Simmons S, Kagawa Y, et al. Interferon-? acts on the S/G2/M phases to induce apoptosis in the G1 phase of an IFNAR2-expressing hepatocellular carcinoma cell line. J Biol Chem. 2014;289:23786-95 pubmed publisher
  17. Doceul V, Chauveau E, Lara E, Breard E, Sailleau C, Zientara S, et al. Dual modulation of type I interferon response by bluetongue virus. J Virol. 2014;88:10792-802 pubmed publisher
  18. M Parrula M, Fernandez S, Landes K, Huey D, Lairmore M, Niewiesk S. Success of measles virotherapy in ATL depends on type I interferon secretion and responsiveness. Virus Res. 2014;189:206-13 pubmed publisher
  19. Liu Y, Zhang Z, Zhao X, Yu R, Zhang X, Wu S, et al. Enterovirus 71 inhibits cellular type I interferon signaling by downregulating JAK1 protein expression. Viral Immunol. 2014;27:267-76 pubmed publisher
  20. Kadota S, Nagata K. Silencing of IFN-stimulated gene transcription is regulated by histone H1 and its chaperone TAF-I. Nucleic Acids Res. 2014;42:7642-53 pubmed publisher
  21. Mathieu M, Miles A, Ahmad M, Buczek M, Pockley A, Rees R, et al. The helicase HAGE prevents interferon-?-induced PML expression in ABCB5+ malignant melanoma-initiating cells by promoting the expression of SOCS1. Cell Death Dis. 2014;5:e1061 pubmed publisher
  22. Lam E, Stein S, Falck Pedersen E. Adenovirus detection by the cGAS/STING/TBK1 DNA sensing cascade. J Virol. 2014;88:974-81 pubmed publisher
  23. Hou Z, Han Q, Zhang C, Tian Z, Zhang J. miR146a impairs the IFN-induced anti-HBV immune response by downregulating STAT1 in hepatocytes. Liver Int. 2014;34:58-68 pubmed publisher
  24. Amalraj J, Cutler S, Ghazawi I, Boyle G, Ralph S. REST negatively and ISGF3 positively regulate the human STAT1 gene in melanoma. Mol Cancer Ther. 2013;12:1288-98 pubmed publisher
  25. Dickensheets H, Sheikh F, Park O, Gao B, Donnelly R. Interferon-lambda (IFN-?) induces signal transduction and gene expression in human hepatocytes, but not in lymphocytes or monocytes. J Leukoc Biol. 2013;93:377-85 pubmed publisher
  26. Shakya R, Gonda T, Quante M, Salas M, Kim S, Brooks J, et al. Hypomethylating therapy in an aggressive stroma-rich model of pancreatic carcinoma. Cancer Res. 2013;73:885-96 pubmed publisher
  27. Steen H, Nogusa S, Thapa R, Basagoudanavar S, Gill A, Merali S, et al. Identification of STAT2 serine 287 as a novel regulatory phosphorylation site in type I interferon-induced cellular responses. J Biol Chem. 2013;288:747-58 pubmed publisher