This is a Validated Antibody Database (VAD) review about human SRC3, based on 16 published articles (read how Labome selects the articles), using SRC3 antibody in all methods. It is aimed to help Labome visitors find the most suited SRC3 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
SRC3 synonym: ACTR; AIB-1; AIB1; CAGH16; CTG26; KAT13B; RAC3; SRC-3; SRC3; TNRC14; TNRC16; TRAM-1; bHLHe42; pCIP

Knockout validation
Cell Signaling Technology
domestic rabbit monoclonal (5E11)
  • western blot knockout validation; human; fig 4
  • immunoprecipitation; human; fig 4
In order to investigate Tead4-mediated transcriptional networks in various types of cancer cells, Cell Signaling Technology SRC3 antibody (Cell signaling, 2126) was used in western blot knockout validation on human samples (fig 4) and in immunoprecipitation on human samples (fig 4). Cell Rep (2016) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (5E11)
  • western blot knockout validation; mouse; fig 1
  • immunohistochemistry - paraffin section; mouse; fig 1
Cell Signaling Technology SRC3 antibody (Cell Signaling, 2126) was used in western blot knockout validation on mouse samples (fig 1) and in immunohistochemistry - paraffin section on mouse samples (fig 1). Int J Biol Sci (2015) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (5E11)
  • immunohistochemistry knockout validation; mouse; fig 1
In order to determine requirement for steroid receptor coactivator-3 in developing neuroendocrine tumor in the mouse prostate, Cell Signaling Technology SRC3 antibody (Cell Signaling, 2126) was used in immunohistochemistry knockout validation on mouse samples (fig 1). Int J Biol Sci (2014) ncbi
Abcam
domestic rabbit polyclonal
  • western blot; human; fig 1
Abcam SRC3 antibody (Abcam, ab2831) was used in western blot on human samples (fig 1). Mol Cells (2016) ncbi
mouse monoclonal (AX15.3)
  • chromatin immunoprecipitation; human
Abcam SRC3 antibody (Abcam, ab2782) was used in chromatin immunoprecipitation on human samples . BMC Cancer (2013) ncbi
Invitrogen
domestic rabbit polyclonal
In order to analyze the regulation of gestational length in caspase-3 and -7 dependent involving uterine endoplasmic reticulum stress-unfolded protein response, Invitrogen SRC3 antibody (Thermo Fisher Scientific, PA1-845) was used . Proc Natl Acad Sci U S A (2015) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (5E11)
  • western blot; human; 1:1000; loading ...; fig s4a
Cell Signaling Technology SRC3 antibody (Cell Signaling Technology, 2126) was used in western blot on human samples at 1:1000 (fig s4a). Front Oncol (2020) ncbi
domestic rabbit monoclonal (5E11)
  • immunohistochemistry; human; loading ...; fig 3a
  • western blot; human; loading ...; fig 2g
Cell Signaling Technology SRC3 antibody (Cell Signaling Technology, 2126) was used in immunohistochemistry on human samples (fig 3a) and in western blot on human samples (fig 2g). Cancer Lett (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:200; fig st1
In order to identify and characterize alterations in signal transduction that occur during the development Lapatinib resistance, Cell Signaling Technology SRC3 antibody (Cell Signaling, 2979) was used in western blot on human samples at 1:200 (fig st1). Nat Commun (2016) ncbi
domestic rabbit monoclonal (5E11)
  • western blot; human; 1:200; fig st1
In order to identify and characterize alterations in signal transduction that occur during the development Lapatinib resistance, Cell Signaling Technology SRC3 antibody (Cell Signaling, 2126) was used in western blot on human samples at 1:200 (fig st1). Nat Commun (2016) ncbi
domestic rabbit monoclonal (5E11)
  • western blot; mouse; loading ...; fig 3a
Cell Signaling Technology SRC3 antibody (Cell Signaling, 5E11) was used in western blot on mouse samples (fig 3a). J Steroid Biochem Mol Biol (2017) ncbi
domestic rabbit monoclonal (5E11)
  • western blot knockout validation; human; fig 4
  • immunoprecipitation; human; fig 4
In order to investigate Tead4-mediated transcriptional networks in various types of cancer cells, Cell Signaling Technology SRC3 antibody (Cell signaling, 2126) was used in western blot knockout validation on human samples (fig 4) and in immunoprecipitation on human samples (fig 4). Cell Rep (2016) ncbi
domestic rabbit monoclonal (5E11)
  • western blot knockout validation; mouse; fig 1
  • immunohistochemistry - paraffin section; mouse; fig 1
Cell Signaling Technology SRC3 antibody (Cell Signaling, 2126) was used in western blot knockout validation on mouse samples (fig 1) and in immunohistochemistry - paraffin section on mouse samples (fig 1). Int J Biol Sci (2015) ncbi
domestic rabbit monoclonal (5E11)
  • immunohistochemistry knockout validation; mouse; fig 1
In order to determine requirement for steroid receptor coactivator-3 in developing neuroendocrine tumor in the mouse prostate, Cell Signaling Technology SRC3 antibody (Cell Signaling, 2126) was used in immunohistochemistry knockout validation on mouse samples (fig 1). Int J Biol Sci (2014) ncbi
domestic rabbit monoclonal (5E11)
  • immunohistochemistry - paraffin section; human; 1:75; loading ...; fig 1a
  • western blot; human; 1:1000; loading ...; fig 1d
In order to study the role of amplified in breast cancer 1 in ductal carcinoma in situ development and maintenance, Cell Signaling Technology SRC3 antibody (Cell Signaling, 5E11) was used in immunohistochemistry - paraffin section on human samples at 1:75 (fig 1a) and in western blot on human samples at 1:1000 (fig 1d). Oncogene (2014) ncbi
BD Biosciences
mouse monoclonal (34/AIB-1)
  • western blot; human; loading ...; fig 3c
BD Biosciences SRC3 antibody (BD, 611104) was used in western blot on human samples (fig 3c). Nat Med (2017) ncbi
mouse monoclonal (34/AIB-1)
  • western blot; human; loading ...
In order to analyze the context specificity of signaling networks within a causal conceptual framework using reverse-phase protein array time-course assays and network analysis approaches, BD Biosciences SRC3 antibody (BD Biosciences, 611105) was used in western blot on human samples . Cell Syst (2017) ncbi
mouse monoclonal (34/AIB-1)
  • chromatin immunoprecipitation; human; loading ...; fig 3g
BD Biosciences SRC3 antibody (BD Biosciences, 611105) was used in chromatin immunoprecipitation on human samples (fig 3g). Oncogene (2017) ncbi
mouse monoclonal (34/AIB-1)
  • immunohistochemistry - paraffin section; human; 1:50; fig s1
In order to utilize ovarian cancer xenograft models to study dynamic modulation of phosphoprotein expression, BD Biosciences SRC3 antibody (BD Biosciences, 61105) was used in immunohistochemistry - paraffin section on human samples at 1:50 (fig s1). BMC Cancer (2016) ncbi
mouse monoclonal (34/AIB-1)
  • other; human; loading ...; fig st1
In order to use size exclusion chromatography-microsphere-based affinity proteomics to study clinical samples obtained from pediatric acute leukemia patients, BD Biosciences SRC3 antibody (BD, 34) was used in other on human samples (fig st1). Mol Cell Proteomics (2016) ncbi
Articles Reviewed
  1. Fang M, Zhang M, Wang Y, Wei F, Wu J, Mou X, et al. Long Noncoding RNA AFAP1-AS1 Is a Critical Regulator of Nasopharyngeal Carcinoma Tumorigenicity. Front Oncol. 2020;10:601055 pubmed publisher
  2. Song X, Chen H, Zhang C, Yu Y, Chen Z, Liang H, et al. SRC-3 inhibition blocks tumor growth of pancreatic ductal adenocarcinoma. Cancer Lett. 2019;442:310-319 pubmed publisher
  3. Zhang P, Wang D, Zhao Y, Ren S, Gao K, Ye Z, et al. Intrinsic BET inhibitor resistance in SPOP-mutated prostate cancer is mediated by BET protein stabilization and AKT-mTORC1 activation. Nat Med. 2017;23:1055-1062 pubmed publisher
  4. Hill S, Nesser N, Johnson Camacho K, Jeffress M, Johnson A, Boniface C, et al. Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling. Cell Syst. 2017;4:73-83.e10 pubmed publisher
  5. Harrod A, Fulton J, Nguyen V, Periyasamy M, Ramos Garcia L, Lai C, et al. Genomic modelling of the ESR1 Y537S mutation for evaluating function and new therapeutic approaches for metastatic breast cancer. Oncogene. 2017;36:2286-2296 pubmed publisher
  6. You D, Zhao H, Wang Y, Jiao Y, Lu M, Yan S. Acetylation Enhances the Promoting Role of AIB1 in Breast Cancer Cell Proliferation. Mol Cells. 2016;39:663-8 pubmed publisher
  7. Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed publisher
  8. Patrick N, Griggs C, Icenogle A, Gilpatrick M, Kadiyala V, Jaime Frias R, et al. Class I lysine deacetylases promote glucocorticoid-induced transcriptional repression through functional interaction with LSD1. J Steroid Biochem Mol Biol. 2017;167:1-13 pubmed publisher
  9. Koussounadis A, Langdon S, Um I, Kay C, Francis K, Harrison D, et al. Dynamic modulation of phosphoprotein expression in ovarian cancer xenograft models. BMC Cancer. 2016;16:205 pubmed publisher
  10. Liu X, Li H, Rajurkar M, Li Q, Cotton J, Ou J, et al. Tead and AP1 Coordinate Transcription and Motility. Cell Rep. 2016;14:1169-1180 pubmed publisher
  11. Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
  12. Kyathanahalli C, Organ K, Moreci R, Anamthathmakula P, Hassan S, Caritis S, et al. Uterine endoplasmic reticulum stress-unfolded protein response regulation of gestational length is caspase-3 and -7-dependent. Proc Natl Acad Sci U S A. 2015;112:14090-5 pubmed publisher
  13. Chen X, Qin L, Liu Z, Liao L, Martin J, Xu J. Knockout of SRC-1 and SRC-3 in Mice Decreases Cardiomyocyte Proliferation and Causes a Noncompaction Cardiomyopathy Phenotype. Int J Biol Sci. 2015;11:1056-72 pubmed publisher
  14. Tien J, Liao L, Liu Y, Liu Z, Lee D, Wang F, et al. The steroid receptor coactivator-3 is required for developing neuroendocrine tumor in the mouse prostate. Int J Biol Sci. 2014;10:1116-27 pubmed publisher
  15. Wagner M, Koslowski M, Paret C, Schmidt M, Tureci O, Sahin U. NCOA3 is a selective co-activator of estrogen receptor ?-mediated transactivation of PLAC1 in MCF-7 breast cancer cells. BMC Cancer. 2013;13:570 pubmed publisher
  16. Ory V, Tassi E, Cavalli L, Sharif G, Saenz F, Baker T, et al. The nuclear coactivator amplified in breast cancer 1 maintains tumor-initiating cells during development of ductal carcinoma in situ. Oncogene. 2014;33:3033-42 pubmed publisher