This is a Validated Antibody Database (VAD) review about human SPTLC1, based on 3 published articles (read how Labome selects the articles), using SPTLC1 antibody in all methods. It is aimed to help Labome visitors find the most suited SPTLC1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
SPTLC1 synonym: HSAN1; HSN1; LBC1; LCB1; SPT1; SPTI

Knockout validation
Santa Cruz Biotechnology
mouse monoclonal (H-1)
  • western blot knockout validation; mouse; 1:1000; loading ...; fig 1c
Santa Cruz Biotechnology SPTLC1 antibody (Santa Cruz, sc-374143) was used in western blot knockout validation on mouse samples at 1:1000 (fig 1c). elife (2022) ncbi
Santa Cruz Biotechnology
mouse monoclonal (H-1)
  • western blot knockout validation; mouse; 1:1000; loading ...; fig 1c
Santa Cruz Biotechnology SPTLC1 antibody (Santa Cruz, sc-374143) was used in western blot knockout validation on mouse samples at 1:1000 (fig 1c). elife (2022) ncbi
mouse monoclonal (H-1)
  • western blot; mouse; 1:1000; loading ...; fig 4b
Santa Cruz Biotechnology SPTLC1 antibody (Santa Cruz, sc-374143) was used in western blot on mouse samples at 1:1000 (fig 4b). elife (2019) ncbi
mouse monoclonal (49)
  • western blot; mouse
Santa Cruz Biotechnology SPTLC1 antibody (Santa Cruz Biotechnology, sc-136076) was used in western blot on mouse samples . PLoS ONE (2015) ncbi
Articles Reviewed
  1. Kuo A, Checa A, Niaudet C, Jung B, Fu Z, Wheelock C, et al. Murine endothelial serine palmitoyltransferase 1 (SPTLC1) is required for vascular development and systemic sphingolipid homeostasis. elife. 2022;11: pubmed publisher
  2. Clarke B, Majumder S, Zhu H, Lee Y, Kono M, Li C, et al. The Ormdl genes regulate the sphingolipid synthesis pathway to ensure proper myelination and neurologic function in mice. elife. 2019;8: pubmed publisher
  3. Wang W, Fromm M. Sphingolipids are required for efficient triacylglycerol loss in conjugated linoleic Acid treated adipocytes. PLoS ONE. 2015;10:e0119005 pubmed publisher