This is a Validated Antibody Database (VAD) review about human SPINT2, based on 2 published articles (read how Labome selects the articles), using SPINT2 antibody in all methods. It is aimed to help Labome visitors find the most suited SPINT2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
SPINT2 synonym: DIAR3; HAI-2; HAI2; Kop; kunitz-type protease inhibitor 2; hepatocyte growth factor activator inhibitor type 2; serine protease inhibitor, Kunitz type, 2; testicular tissue protein Li 183

R&D Systems
goat polyclonal
  • western blot; human; loading ...; fig 6a
R&D Systems SPINT2 antibody (R&D Systems, AF1106) was used in western blot on human samples (fig 6a). Oncotarget (2015) ncbi
goat polyclonal
  • western blot; mouse
In order to determine the effect of ablating HAI-1 and HAI-2 on endogenous matriptase expression, subcellular localization, and activation in polarized intestinal epithelial cells, R&D Systems SPINT2 antibody (R&D Systems, AF1107) was used in western blot on mouse samples . J Biol Chem (2014) ncbi
goat polyclonal
  • immunoprecipitation; human
In order to determine the effect of ablating HAI-1 and HAI-2 on endogenous matriptase expression, subcellular localization, and activation in polarized intestinal epithelial cells, R&D Systems SPINT2 antibody (R&D Systems, AF1106) was used in immunoprecipitation on human samples . J Biol Chem (2014) ncbi
Articles Reviewed
  1. Martin E, Buzza M, Driesbaugh K, Liu S, Fortenberry Y, Leppla S, et al. Targeting the membrane-anchored serine protease testisin with a novel engineered anthrax toxin prodrug to kill tumor cells and reduce tumor burden. Oncotarget. 2015;6:33534-53 pubmed publisher
  2. Friis S, Sales K, Schafer J, Vogel L, Kataoka H, Bugge T. The protease inhibitor HAI-2, but not HAI-1, regulates matriptase activation and shedding through prostasin. J Biol Chem. 2014;289:22319-32 pubmed publisher