This is a Validated Antibody Database (VAD) review about human SPEN, based on 2 published articles (read how Labome selects the articles), using SPEN antibody in all methods. It is aimed to help Labome visitors find the most suited SPEN antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
SPEN synonym: HIAA0929; MINT; RBM15C; SHARP; msx2-interacting protein; Msx2 interacting nuclear target (MINT) homolog; SMART/HDAC1-associated repressor protein; nuclear receptor transcription cofactor; spen homolog, transcriptional regulator

Bethyl
rabbit polyclonal
  • RNA immunoprecipitation; mouse; loading ...; fig s9g
Bethyl SPEN antibody (Bethyl Laboratories, A301-119A) was used in RNA immunoprecipitation on mouse samples (fig s9g). Science (2016) ncbi
Sigma-Aldrich
rabbit polyclonal
  • chromatin immunoprecipitation; human; fig 4h
  • immunoprecipitation; human; fig 2a
  • western blot; human; fig 2a
Sigma-Aldrich SPEN antibody (Sigma, HPA015825) was used in chromatin immunoprecipitation on human samples (fig 4h), in immunoprecipitation on human samples (fig 2a) and in western blot on human samples (fig 2a). Cancer Res (2015) ncbi
Articles Reviewed
  1. Chen C, Blanco M, Jackson C, Aznauryan E, Ollikainen N, Surka C, et al. Xist recruits the X chromosome to the nuclear lamina to enable chromosome-wide silencing. Science. 2016;354:468-472 pubmed
  2. Légaré S, Cavallone L, Mamo A, Chabot C, Sirois I, Magliocco A, et al. The Estrogen Receptor Cofactor SPEN Functions as a Tumor Suppressor and Candidate Biomarker of Drug Responsiveness in Hormone-Dependent Breast Cancers. Cancer Res. 2015;75:4351-63 pubmed publisher