This is a Validated Antibody Database (VAD) review about human SORL1, based on 6 published articles (read how Labome selects the articles), using SORL1 antibody in all methods. It is aimed to help Labome visitors find the most suited SORL1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
SORL1 synonym: C11orf32; LR11; LRP9; SORLA; SorLA-1; gp250

Knockout validation
Abcam
domestic rabbit monoclonal (EPR14670)
  • western blot knockout validation; human; loading ...; fig 2d, 3b
Abcam SORL1 antibody (Abcam, Ab190684) was used in western blot knockout validation on human samples (fig 2d, 3b). Cell Rep (2021) ncbi
BD Biosciences
mouse monoclonal (48/LR11)
  • western blot knockout validation; pigs ; 1:500; loading ...; fig 2d
BD Biosciences SORL1 antibody (BD Biosciences, 612633) was used in western blot knockout validation on pigs samples at 1:500 (fig 2d). Cell Rep Med (2022) ncbi
Abcam
domestic rabbit monoclonal (EPR14670)
  • western blot knockout validation; human; loading ...; fig 2d, 3b
Abcam SORL1 antibody (Abcam, Ab190684) was used in western blot knockout validation on human samples (fig 2d, 3b). Cell Rep (2021) ncbi
domestic rabbit monoclonal (EPR14670)
  • western blot; mouse; loading ...; fig 2a
Abcam SORL1 antibody (Abcam, ab190684) was used in western blot on mouse samples (fig 2a). Aging (Albany NY) (2021) ncbi
Santa Cruz Biotechnology
mouse monoclonal (48)
  • western blot; mouse; fig 6
In order to characterize the role of ARHGAP33 in intracellular trafficking of TRKB and neuropsychiatric disorder pathophysiology, Santa Cruz Biotechnology SORL1 antibody (Santa Cruz, sc 136073) was used in western blot on mouse samples (fig 6). Nat Commun (2016) ncbi
BD Biosciences
mouse monoclonal (48/LR11)
  • western blot knockout validation; pigs ; 1:500; loading ...; fig 2d
BD Biosciences SORL1 antibody (BD Biosciences, 612633) was used in western blot knockout validation on pigs samples at 1:500 (fig 2d). Cell Rep Med (2022) ncbi
mouse monoclonal (48/LR11)
  • immunocytochemistry; human; loading ...; fig 3g
BD Biosciences SORL1 antibody (BD Biosciences, 612633) was used in immunocytochemistry on human samples (fig 3g). Acta Neuropathol (2021) ncbi
mouse monoclonal (48/LR11)
  • western blot; human; loading ...; fig 3d
BD Biosciences SORL1 antibody (BD Bioscience, 612633) was used in western blot on human samples (fig 3d). Cell Mol Life Sci (2018) ncbi
Articles Reviewed
  1. Andersen O, B xf8 gh N, Landau A, Pl xf8 en G, Jensen A, Monti G, et al. A genetically modified minipig model for Alzheimer's disease with SORL1 haploinsufficiency. Cell Rep Med. 2022;3:100740 pubmed publisher
  2. Hung C, Tuck E, Stubbs V, van der Lee S, Aalfs C, van Spaendonk R, et al. SORL1 deficiency in human excitatory neurons causes APP-dependent defects in the endolysosome-autophagy network. Cell Rep. 2021;35:109259 pubmed publisher
  3. Grochowska M, Carreras Mascaro A, Boumeester V, Natale D, Breedveld G, Geut H, et al. LRP10 interacts with SORL1 in the intracellular vesicle trafficking pathway in non-neuronal brain cells and localises to Lewy bodies in Parkinson's disease and dementia with Lewy bodies. Acta Neuropathol. 2021;142:117-137 pubmed publisher
  4. Wei C, Sun Y, Wang J, Lin D, Cui V, Shi H, et al. LncRNA NONMMUT055714 acts as the sponge of microRNA-7684-5p to protect against postoperative cognitive dysfunction. Aging (Albany NY). 2021;13:12552-12564 pubmed publisher
  5. Mukadam A, Breusegem S, Seaman M. Analysis of novel endosome-to-Golgi retrieval genes reveals a role for PLD3 in regulating endosomal protein sorting and amyloid precursor protein processing. Cell Mol Life Sci. 2018;75:2613-2625 pubmed publisher
  6. Nakazawa T, Hashimoto R, Sakoori K, Sugaya Y, Tanimura A, Hashimotodani Y, et al. Emerging roles of ARHGAP33 in intracellular trafficking of TrkB and pathophysiology of neuropsychiatric disorders. Nat Commun. 2016;7:10594 pubmed publisher