This is a Validated Antibody Database (VAD) review about human SNX1, based on 11 published articles (read how Labome selects the articles), using SNX1 antibody in all methods. It is aimed to help Labome visitors find the most suited SNX1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
SNX1 synonym: HsT17379; VPS5; sorting nexin-1; sorting nexin 1A

Knockout validation
BD Biosciences
mouse monoclonal (51/SNX1)
  • western blot knockout validation; human; 1:1000; loading ...; fig 3b
  • immunocytochemistry; human; 1:100; loading ...; fig s4a
BD Biosciences SNX1 antibody (BD Biosciences, 611482) was used in western blot knockout validation on human samples at 1:1000 (fig 3b) and in immunocytochemistry on human samples at 1:100 (fig s4a). EMBO J (2018) ncbi
Abcam
rabbit monoclonal (EPR7178)
  • western blot; mouse; loading ...; fig 1d
In order to find that CNS-specific snx6-knockout mice exhibit deficits in spatial learning and memory, accompanied with loss of spines from distal dendrites of hippocampal CA1 pyramidal cells, Abcam SNX1 antibody (Abcam, ab134126) was used in western blot on mouse samples (fig 1d). elife (2017) ncbi
rabbit polyclonal
  • immunocytochemistry; human
Abcam SNX1 antibody (Abcam, Ab995) was used in immunocytochemistry on human samples . Traffic (2014) ncbi
Abnova
mouse monoclonal (6H1)
  • western blot; human; loading ...; fig 5c
In order to demonstrate that sorting nexin 1 and 2 are cleaved by initiator caspases during apoptosis, Abnova SNX1 antibody (Abnova, H00006642-M01) was used in western blot on human samples (fig 5c). Cell Death Discov (2017) ncbi
Proteintech Group
rabbit polyclonal
  • immunocytochemistry; mouse
Proteintech Group SNX1 antibody (Proteintech Group, 10304-1-AP) was used in immunocytochemistry on mouse samples . PLoS ONE (2014) ncbi
BD Biosciences
mouse monoclonal (51/SNX1)
  • immunocytochemistry; human; fig s1e
BD Biosciences SNX1 antibody (BD Biosciences, 51) was used in immunocytochemistry on human samples (fig s1e). EMBO J (2018) ncbi
mouse monoclonal (51/SNX1)
  • western blot knockout validation; human; 1:1000; loading ...; fig 3b
  • immunocytochemistry; human; 1:100; loading ...; fig s4a
BD Biosciences SNX1 antibody (BD Biosciences, 611482) was used in western blot knockout validation on human samples at 1:1000 (fig 3b) and in immunocytochemistry on human samples at 1:100 (fig s4a). EMBO J (2018) ncbi
mouse monoclonal (51/SNX1)
  • immunocytochemistry; human; loading ...; fig s1c
  • western blot; human; loading ...; fig s1a
In order to explore the regulatory mechanisms and consequences of tubule fission failure, BD Biosciences SNX1 antibody (BD transduction laboratories, 611482) was used in immunocytochemistry on human samples (fig s1c) and in western blot on human samples (fig s1a). J Cell Biol (2017) ncbi
mouse monoclonal (51/SNX1)
  • western blot; human; loading ...; fig 5a
BD Biosciences SNX1 antibody (BD Biosciences, 611482) was used in western blot on human samples (fig 5a). elife (2017) ncbi
mouse monoclonal (51/SNX1)
  • western blot; human; loading ...; fig 5c
In order to demonstrate that sorting nexin 1 and 2 are cleaved by initiator caspases during apoptosis, BD Biosciences SNX1 antibody (BD Biosciences, 611482) was used in western blot on human samples (fig 5c). Cell Death Discov (2017) ncbi
mouse monoclonal (51/SNX1)
  • immunocytochemistry; human; loading ...; fig s16
In order to show that 2-hydroxyoleic acid treatment alters cell signaling and intracellular transport, BD Biosciences SNX1 antibody (BD Biosciences, 611482) was used in immunocytochemistry on human samples (fig s16). Oncotarget (2016) ncbi
mouse monoclonal (51/SNX1)
  • western blot; human; fig 4a
In order to promote biogenesis of membrane-trafficking intermediates by engagement of OCRL1 with F-BAR protein pacsin 2, BD Biosciences SNX1 antibody (BD Biosciences, 611482) was used in western blot on human samples (fig 4a). Mol Biol Cell (2016) ncbi
mouse monoclonal (51/SNX1)
  • immunocytochemistry; human
In order to determine the interactome of human VPS35, BD Biosciences SNX1 antibody (BD Biosciences, 611482) was used in immunocytochemistry on human samples . J Cell Sci (2014) ncbi
Articles Reviewed
  1. Takada N, Naito T, Inoue T, Nakayama K, Takatsu H, Shin H. Phospholipid-flipping activity of P4-ATPase drives membrane curvature. EMBO J. 2018;37: pubmed publisher
  2. Jimenez Orgaz A, Kvainickas A, Nägele H, Denner J, Eimer S, Dengjel J, et al. Control of RAB7 activity and localization through the retromer-TBC1D5 complex enables RAB7-dependent mitophagy. EMBO J. 2018;37:235-254 pubmed publisher
  3. Allison R, Edgar J, Pearson G, Rizo T, Newton T, Günther S, et al. Defects in ER-endosome contacts impact lysosome function in hereditary spastic paraplegia. J Cell Biol. 2017;216:1337-1355 pubmed publisher
  4. Elwell C, Czudnochowski N, Von Dollen J, Johnson J, Nakagawa R, Mirrashidi K, et al. Chlamydia interfere with an interaction between the mannose-6-phosphate receptor and sorting nexins to counteract host restriction. elife. 2017;6: pubmed publisher
  5. Duclos C, Champagne A, Carrier J, Saucier C, Lavoie C, Denault J. Caspase-mediated proteolysis of the sorting nexin 2 disrupts retromer assembly and potentiates Met/hepatocyte growth factor receptor signaling. Cell Death Discov. 2017;3:16100 pubmed publisher
  6. Niu Y, Dai Z, Liu W, Zhang C, Yang Y, Guo Z, et al. Ablation of SNX6 leads to defects in synaptic function of CA1 pyramidal neurons and spatial memory. elife. 2017;6: pubmed publisher
  7. Torgersen M, Klokk T, Kavaliauskiene S, Klose C, Simons K, Skotland T, et al. The anti-tumor drug 2-hydroxyoleic acid (Minerval) stimulates signaling and retrograde transport. Oncotarget. 2016;7:86871-86888 pubmed publisher
  8. Billcliff P, Noakes C, Mehta Z, Yan G, Mak L, Woscholski R, et al. OCRL1 engages with the F-BAR protein pacsin 2 to promote biogenesis of membrane-trafficking intermediates. Mol Biol Cell. 2016;27:90-107 pubmed publisher
  9. McGough I, Steinberg F, Gallon M, Yatsu A, Ohbayashi N, Heesom K, et al. Identification of molecular heterogeneity in SNX27-retromer-mediated endosome-to-plasma-membrane recycling. J Cell Sci. 2014;127:4940-53 pubmed publisher
  10. Yamasaki T, Suzuki A, Hasebe R, Horiuchi M. Comparison of the anti-prion mechanism of four different anti-prion compounds, anti-PrP monoclonal antibody 44B1, pentosan polysulfate, chlorpromazine, and U18666A, in prion-infected mouse neuroblastoma cells. PLoS ONE. 2014;9:e106516 pubmed publisher
  11. Macdonald E, Urbé S, Clague M. USP8 controls the trafficking and sorting of lysosomal enzymes. Traffic. 2014;15:879-88 pubmed publisher