This is a Validated Antibody Database (VAD) review about human SNRPC, based on 7 published articles (read how Labome selects the articles), using SNRPC antibody in all methods. It is aimed to help Labome visitors find the most suited SNRPC antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
SNRPC synonym: U1C; Yhc1; U1 small nuclear ribonucleoprotein C; U1 small nuclear RNP specific C; U1 snRNP C; U1 snRNP protein C

Santa Cruz Biotechnology
rat monoclonal (4H12)
  • western blot; mouse; fig 7
  • immunocytochemistry; rat; 1:100; fig 7
In order to characterize the involvement of concerted non-productive splicing of post-transcriptional regulators that involves the alternative splicing program of differentiatied smooth muscle cells, Santa Cruz Biotechnology SNRPC antibody (Santa Cruz Biotechnology, sc-101549) was used in western blot on mouse samples (fig 7) and in immunocytochemistry on rat samples at 1:100 (fig 7). Nucleic Acids Res (2016) ncbi
rat monoclonal (4H12)
  • other; human; loading ...; fig st1
In order to use size exclusion chromatography-microsphere-based affinity proteomics to study clinical samples obtained from pediatric acute leukemia patients, Santa Cruz Biotechnology SNRPC antibody (SCBT, 4H12) was used in other on human samples (fig st1). Mol Cell Proteomics (2016) ncbi
rat monoclonal (5C9)
  • immunocytochemistry; human; 1:1000; loading ...; fig 2A
  • western blot; human; loading ...; fig 1A
Santa Cruz Biotechnology SNRPC antibody (Santa Cruz, 5C9) was used in immunocytochemistry on human samples at 1:1000 (fig 2A) and in western blot on human samples (fig 1A). Nucleic Acids Res (2015) ncbi
Abcam
rabbit monoclonal (EPR16034)
  • immunoprecipitation; human; loading ...; fig 5a
Abcam SNRPC antibody (abcam, ab192028) was used in immunoprecipitation on human samples (fig 5a). Nucleic Acids Res (2018) ncbi
Bethyl
rabbit polyclonal
  • western blot; human; loading ...; fig 4c
Bethyl SNRPC antibody (Bethyl, A303-947A) was used in western blot on human samples (fig 4c). J Mol Biol (2018) ncbi
Sigma-Aldrich
rat monoclonal (4H12)
  • western blot; human
In order to characterize acetylcholinesterase mutations, Sigma-Aldrich SNRPC antibody (Sigma-Aldrich, 4H12) was used in western blot on human samples . Sci Rep (2015) ncbi
rat monoclonal (4H12)
  • western blot; human; 1:1000; fig 1
In order to study how altered association with SMN and U1-snRNP can cause gain and loss of function by ALS-causative mutations in FUS/TLS, Sigma-Aldrich SNRPC antibody (Sigma, SAB4200188) was used in western blot on human samples at 1:1000 (fig 1). Nat Commun (2015) ncbi
Articles Reviewed
  1. Sithole N, Williams C, Vaughan A, Kenyon J, Lever A. DDX17 Specifically, and Independently of DDX5, Controls Use of the HIV A4/5 Splice Acceptor Cluster and Is Essential for Efficient Replication of HIV. J Mol Biol. 2018;430:3111-3128 pubmed publisher
  2. Kralovicova J, Sevcikova I, Stejskalova E, Obuca M, Hiller M, Stanek D, et al. PUF60-activated exons uncover altered 3' splice-site selection by germline missense mutations in a single RRM. Nucleic Acids Res. 2018;46:6166-6187 pubmed publisher
  3. Llorian M, Gooding C, Bellora N, Hallegger M, Buckroyd A, Wang X, et al. The alternative splicing program of differentiated smooth muscle cells involves concerted non-productive splicing of post-transcriptional regulators. Nucleic Acids Res. 2016;44:8933-8950 pubmed
  4. Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
  5. Rahman M, Azuma Y, Nasrin F, Takeda J, Nazim M, Bin Ahsan K, et al. SRSF1 and hnRNP H antagonistically regulate splicing of COLQ exon 16 in a congenital myasthenic syndrome. Sci Rep. 2015;5:13208 pubmed publisher
  6. Yu Y, Chi B, Xia W, Gangopadhyay J, Yamazaki T, Winkelbauer Hurt M, et al. U1 snRNP is mislocalized in ALS patient fibroblasts bearing NLS mutations in FUS and is required for motor neuron outgrowth in zebrafish. Nucleic Acids Res. 2015;43:3208-18 pubmed publisher
  7. Sun S, Ling S, Qiu J, Albuquerque C, Zhou Y, Tokunaga S, et al. ALS-causative mutations in FUS/TLS confer gain and loss of function by altered association with SMN and U1-snRNP. Nat Commun. 2015;6:6171 pubmed publisher