This is a Validated Antibody Database (VAD) review about human SLC7A5, based on 10 published articles (read how Labome selects the articles), using SLC7A5 antibody in all methods. It is aimed to help Labome visitors find the most suited SLC7A5 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
SLC7A5 synonym: 4F2LC; CD98; D16S469E; E16; LAT1; MPE16

Knockout validation
TRANS GENIC
domestic rabbit polyclonal
  • immunohistochemistry; human; 1:200; loading ...; fig 7a
  • western blot knockout validation; mouse; 1:1000; loading ...; fig 3a
TRANS GENIC SLC7A5 antibody (TransGenic, E026) was used in immunohistochemistry on human samples at 1:200 (fig 7a) and in western blot knockout validation on mouse samples at 1:1000 (fig 3a). Mol Cell Biol (2017) ncbi
TRANS GENIC
domestic rabbit polyclonal
  • immunocytochemistry knockout validation; human; 1:1000; fig 1
  • western blot knockout validation; human; 1:1000; fig 1
In order to demonstrate the key role of essential amino acid transport in the control of mTORC1 and tumor growth caused by genetic disruption of the multifunctional CD98/LAT1 complex, TRANS GENIC SLC7A5 antibody (TransGenic, KE026) was used in immunocytochemistry knockout validation on human samples at 1:1000 (fig 1) and in western blot knockout validation on human samples at 1:1000 (fig 1). Cancer Res (2016) ncbi
Santa Cruz Biotechnology
mouse monoclonal (D-10)
  • immunohistochemistry; human; 1:150; loading ...; fig 5a
Santa Cruz Biotechnology SLC7A5 antibody (SantaCruz, sc-374232) was used in immunohistochemistry on human samples at 1:150 (fig 5a). J Clin Med (2022) ncbi
mouse monoclonal (D-10)
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 1f
Santa Cruz Biotechnology SLC7A5 antibody (Santa, sc-374232) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 1f). Arthritis Res Ther (2020) ncbi
mouse monoclonal (D-10)
  • immunohistochemistry; human; 1:50; loading ...; fig 4c
Santa Cruz Biotechnology SLC7A5 antibody (Santa Cruz, sc-374232) was used in immunohistochemistry on human samples at 1:50 (fig 4c). Science (2020) ncbi
mouse monoclonal (D-10)
  • western blot; human; 1:200; loading ...; fig 3a
Santa Cruz Biotechnology SLC7A5 antibody (SantaCruz, sc-374232) was used in western blot on human samples at 1:200 (fig 3a). Thromb Haemost (2017) ncbi
Abcam
domestic rabbit monoclonal (EPR17573)
  • immunohistochemistry; human; fig 6e
  • western blot; human; loading ...; fig s7a
Abcam SLC7A5 antibody (Abcam, ab208776) was used in immunohistochemistry on human samples (fig 6e) and in western blot on human samples (fig s7a). Mol Cell (2021) ncbi
Invitrogen
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; fig 1a
Invitrogen SLC7A5 antibody (Thermo Fisher Scientific, PA5-34215) was used in immunohistochemistry - paraffin section on human samples (fig 1a). Brain Tumor Pathol (2017) ncbi
TRANS GENIC
domestic rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; 1:500; loading ...; fig 2a
TRANS GENIC SLC7A5 antibody (TransGenicInc, KE026) was used in immunohistochemistry - frozen section on mouse samples at 1:500 (fig 2a). Stem Cell Reports (2020) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; human; 1:200; loading ...; fig 7a
  • western blot knockout validation; mouse; 1:1000; loading ...; fig 3a
TRANS GENIC SLC7A5 antibody (TransGenic, E026) was used in immunohistochemistry on human samples at 1:200 (fig 7a) and in western blot knockout validation on mouse samples at 1:1000 (fig 3a). Mol Cell Biol (2017) ncbi
domestic rabbit polyclonal
  • immunocytochemistry knockout validation; human; 1:1000; fig 1
  • western blot knockout validation; human; 1:1000; fig 1
In order to demonstrate the key role of essential amino acid transport in the control of mTORC1 and tumor growth caused by genetic disruption of the multifunctional CD98/LAT1 complex, TRANS GENIC SLC7A5 antibody (TransGenic, KE026) was used in immunocytochemistry knockout validation on human samples at 1:1000 (fig 1) and in western blot knockout validation on human samples at 1:1000 (fig 1). Cancer Res (2016) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 4d
In order to investigate the phenotypic changes caused by Met expression levels in metastatic melanoma., Cell Signaling Technology SLC7A5 antibody (Cell Signaling, 5347) was used in western blot on mouse samples at 1:1000 (fig 4d). Oncotarget (2016) ncbi
Articles Reviewed
  1. Malinowski D, Grzeg xf3 x142 kowski P, Piotrowska K, S x142 ojewski M, Dro x17a dzik M. Membrane Transporters and Carriers in Human Seminal Vesicles. J Clin Med. 2022;11: pubmed publisher
  2. Heider M, Eichner R, Stroh J, Morath V, Kuisl A, Zecha J, et al. The IMiD target CRBN determines HSP90 activity toward transmembrane proteins essential in multiple myeloma. Mol Cell. 2021;: pubmed publisher
  3. Xu J, Jiang C, Cai Y, Guo Y, Wang X, Zhang J, et al. Intervening upregulated SLC7A5 could mitigate inflammatory mediator by mTOR-P70S6K signal in rheumatoid arthritis synoviocytes. Arthritis Res Ther. 2020;22:200 pubmed publisher
  4. Pellegrini L, Bonfio C, Chadwick J, Begum F, Skehel M, Lancaster M. Human CNS barrier-forming organoids with cerebrospinal fluid production. Science. 2020;: pubmed publisher
  5. Mayerl S, Heuer H, Ffrench Constant C. Hippocampal Neurogenesis Requires Cell-Autonomous Thyroid Hormone Signaling. Stem Cell Reports. 2020;14:845-860 pubmed publisher
  6. Cicone F, Minniti G, Oliva M, Carideo L, Prior J, Scopinaro F, et al. Expression of large neutral amino acid transporters LAT1 and LAT2 in medulloblastoma. Brain Tumor Pathol. 2017;34:179-181 pubmed publisher
  7. Dosier L, Premkumar V, Zhu H, Akosman I, Wempe M, McMahon T. Antagonists of the system L neutral amino acid transporter (LAT) promote endothelial adhesivity of human red blood cells. Thromb Haemost. 2017;117:1402-1411 pubmed publisher
  8. Ohgaki R, Ohmori T, Hara S, Nakagomi S, Kanai Azuma M, Kaneda Nakashima K, et al. Essential Roles of L-Type Amino Acid Transporter 1 in Syncytiotrophoblast Development by Presenting Fusogenic 4F2hc. Mol Cell Biol. 2017;37: pubmed publisher
  9. Adachi E, Sakai K, Nishiuchi T, Imamura R, Sato H, Matsumoto K. Different growth and metastatic phenotypes associated with a cell-intrinsic change of Met in metastatic melanoma. Oncotarget. 2016;7:70779-70793 pubmed publisher
  10. Cormerais Y, Giuliano S, Lefloch R, Front B, Durivault J, Tambutte E, et al. Genetic Disruption of the Multifunctional CD98/LAT1 Complex Demonstrates the Key Role of Essential Amino Acid Transport in the Control of mTORC1 and Tumor Growth. Cancer Res. 2016;76:4481-92 pubmed publisher