This is a Validated Antibody Database (VAD) review about human SLC12A3, based on 12 published articles (read how Labome selects the articles), using SLC12A3 antibody in all methods. It is aimed to help Labome visitors find the most suited SLC12A3 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
SLC12A3 synonym: NCC; NCCT; TSC; solute carrier family 12 member 3; Na-Cl cotransporter; Na-Cl symporter; NaCl electroneutral thiazide-sensitive cotransporter; solute carrier family 12 (sodium/chloride transporter), member 3; thiazide-sensitive Na-Cl cotransporter; thiazide-sensitive sodium-chloride cotransporter

StressMarq Biosciences
rabbit polyclonal
  • western blot; mouse; fig 1
StressMarq Biosciences SLC12A3 antibody (StressMarq, SPC-402D) was used in western blot on mouse samples (fig 1). PLoS ONE (2016) ncbi
rabbit polyclonal
  • western blot; mouse; fig 6
StressMarq Biosciences SLC12A3 antibody (StressMarq, SPC-402D) was used in western blot on mouse samples (fig 6). Sci Rep (2015) ncbi
Abcam
rabbit polyclonal
  • immunohistochemistry; mouse; fig 5a
  • western blot; mouse; 1:1000; fig 4a
Abcam SLC12A3 antibody (Abcam, AB95302) was used in immunohistochemistry on mouse samples (fig 5a) and in western blot on mouse samples at 1:1000 (fig 4a). EMBO Mol Med (2015) ncbi
EMD Millipore
rabbit polyclonal
  • immunohistochemistry; rat; 1:300; loading ...; fig 4e
In order to perform a genome-wide meta-analysis of urinary magnesium-to-calcium ratio to identify associated common genetic variants in the general population, EMD Millipore SLC12A3 antibody (Millipore, AB3553) was used in immunohistochemistry on rat samples at 1:300 (fig 4e). Pflugers Arch (2017) ncbi
rabbit polyclonal
  • western blot; mouse; fig 4a
EMD Millipore SLC12A3 antibody (Millipore, AB3553) was used in western blot on mouse samples (fig 4a). Sci Rep (2016) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:1000; fig s6
In order to study a kidney-specific knockout of Sav1 in the mouse suppresses the Hippo pathway which promotes hyperproliferation of renal tubular epithelium, EMD Millipore SLC12A3 antibody (EMD Millipore, AB3553) was used in immunohistochemistry - paraffin section on mouse samples at 1:1000 (fig s6). J Pathol (2016) ncbi
rabbit polyclonal
  • immunohistochemistry; mouse; 1:1000; fig s2
  • western blot; mouse; 1:1000; fig s2
In order to test if GATA5 is a regulator of blood pressure, EMD Millipore SLC12A3 antibody (Millipore, AB3553) was used in immunohistochemistry on mouse samples at 1:1000 (fig s2) and in western blot on mouse samples at 1:1000 (fig s2). Nat Commun (2015) ncbi
rabbit polyclonal
  • immunohistochemistry; mouse; loading ...; fig 2a
  • immunohistochemistry; human; 1:60; loading ...; fig 2a
EMD Millipore SLC12A3 antibody (Millipore, AB3553) was used in immunohistochemistry on mouse samples (fig 2a) and in immunohistochemistry on human samples at 1:60 (fig 2a). Nat Med (2015) ncbi
rabbit polyclonal
  • western blot; mouse
In order to study the effects of ATRAP in the renal distal tubules in response to high salt treatment using wild type and ATRAP transgenic mice, EMD Millipore SLC12A3 antibody (Chemicon, AB3553) was used in western blot on mouse samples . J Am Heart Assoc (2015) ncbi
rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; 1:50
EMD Millipore SLC12A3 antibody (Millipore, AB3553) was used in immunohistochemistry - frozen section on mouse samples at 1:50. Kidney Int (2014) ncbi
rabbit polyclonal
  • immunohistochemistry; human
EMD Millipore SLC12A3 antibody (Millipore, AB3553) was used in immunohistochemistry on human samples . Kidney Int (2014) ncbi
rabbit polyclonal
  • immunohistochemistry; mouse
In order to investigate the role of hepatocyte growth factor receptor, c-met in renoprotection, EMD Millipore SLC12A3 antibody (Millipore, AB3553) was used in immunohistochemistry on mouse samples . Kidney Int (2013) ncbi
Articles Reviewed
  1. Corre T, Olinger E, Harris S, Traglia M, Ulivi S, Lenarduzzi S, et al. Common variants in CLDN14 are associated with differential excretion of magnesium over calcium in urine. Pflugers Arch. 2017;469:91-103 pubmed publisher
  2. Yu H, Yang T, Gao P, Wei X, Zhang H, Xiong S, et al. Caffeine intake antagonizes salt sensitive hypertension through improvement of renal sodium handling. Sci Rep. 2016;6:25746 pubmed publisher
  3. Patel Chamberlin M, Varasteh Kia M, Xu J, Barone S, Zahedi K, Soleimani M. The Role of Epithelial Sodium Channel ENaC and the Apical Cl-/HCO3- Exchanger Pendrin in Compensatory Salt Reabsorption in the Setting of Na-Cl Cotransporter (NCC) Inactivation. PLoS ONE. 2016;11:e0150918 pubmed publisher
  4. Kai T, Tsukamoto Y, Hijiya N, Tokunaga A, Nakada C, Uchida T, et al. Kidney-specific knockout of Sav1 in the mouse promotes hyperproliferation of renal tubular epithelium through suppression of the Hippo pathway. J Pathol. 2016;239:97-108 pubmed publisher
  5. Messaoudi S, He Y, Gutsol A, Wight A, Hébert R, Vilmundarson R, et al. Endothelial Gata5 transcription factor regulates blood pressure. Nat Commun. 2015;6:8835 pubmed publisher
  6. Schumacher F, Siew K, Zhang J, Johnson C, Wood N, Cleary S, et al. Characterisation of the Cullin-3 mutation that causes a severe form of familial hypertension and hyperkalaemia. EMBO Mol Med. 2015;7:1285-306 pubmed publisher
  7. Cheng L, Wu Q, Kortenoeven M, Pisitkun T, Fenton R. A Systems Level Analysis of Vasopressin-mediated Signaling Networks in Kidney Distal Convoluted Tubule Cells. Sci Rep. 2015;5:12829 pubmed publisher
  8. Wang J, Sun C, Gerdes N, Liu C, Liao M, Liu J, et al. Interleukin 18 function in atherosclerosis is mediated by the interleukin 18 receptor and the Na-Cl co-transporter. Nat Med. 2015;21:820-6 pubmed publisher
  9. Wakui H, Uneda K, Tamura K, Ohsawa M, Azushima K, Kobayashi R, et al. Renal tubule angiotensin II type 1 receptor-associated protein promotes natriuresis and inhibits salt-sensitive blood pressure elevation. J Am Heart Assoc. 2015;4:e001594 pubmed publisher
  10. Fretz J, Nelson T, Velazquez H, Xi Y, Moeckel G, Horowitz M. Early B-cell factor 1 is an essential transcription factor for postnatal glomerular maturation. Kidney Int. 2014;85:1091-102 pubmed publisher
  11. Saisawat P, Kohl S, Hilger A, Hwang D, Yung Gee H, Dworschak G, et al. Whole-exome resequencing reveals recessive mutations in TRAP1 in individuals with CAKUT and VACTERL association. Kidney Int. 2014;85:1310-7 pubmed publisher
  12. Zhou D, Tan R, Lin L, Zhou L, Liu Y. Activation of hepatocyte growth factor receptor, c-met, in renal tubules is required for renoprotection after acute kidney injury. Kidney Int. 2013;84:509-20 pubmed publisher