This is a Validated Antibody Database (VAD) review about human SIX2, based on 16 published articles (read how Labome selects the articles), using SIX2 antibody in all methods. It is aimed to help Labome visitors find the most suited SIX2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Knockout validation
Proteintech Group
domestic rabbit polyclonal
  • western blot knockout validation; human; loading ...; fig 4e, e4d, e9c
Proteintech Group SIX2 antibody (Proteintech, 11562-1-AP) was used in western blot knockout validation on human samples (fig 4e, e4d, e9c). Nature (2019) ncbi
Proteintech Group
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; fig 3d
Proteintech Group SIX2 antibody (Proteintech, 11562-1-AP) was used in immunohistochemistry - paraffin section on human samples (fig 3d). Nat Commun (2020) ncbi
domestic rabbit polyclonal
  • western blot knockout validation; human; loading ...; fig 4e, e4d, e9c
Proteintech Group SIX2 antibody (Proteintech, 11562-1-AP) was used in western blot knockout validation on human samples (fig 4e, e4d, e9c). Nature (2019) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; loading ...; fig 1f
Proteintech Group SIX2 antibody (Proteintech, 11562-1-AP) was used in immunohistochemistry on mouse samples (fig 1f). elife (2019) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; human; 1:200; fig 4a
  • western blot; human; 1:600; fig s2
Proteintech Group SIX2 antibody (Proteintech, 11562-1-AP) was used in immunocytochemistry on human samples at 1:200 (fig 4a) and in western blot on human samples at 1:600 (fig s2). PLoS ONE (2018) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; 1:300; fig 2
In order to investigate the roles of NF2, LATS1/2, and YAP in the branching morphogenesis of the mouse kidney, Proteintech Group SIX2 antibody (Proteintech, 11562-1-AP) was used in immunohistochemistry on mouse samples at 1:300 (fig 2). Nat Commun (2016) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; fig 4d
  • western blot; mouse; loading ...; fig 2i
In order to determine the contributions of Osr1 and Wt1 during early nephrogenesis using transgenic mice, Proteintech Group SIX2 antibody (Proteintech, 11562-1-AP) was used in immunohistochemistry - paraffin section on mouse samples (fig 4d) and in western blot on mouse samples (fig 2i). PLoS ONE (2016) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; mouse; 1:200; fig 8a
In order to develop methods to culture mesothelial cells isolated from the mouse omentum and characterize the cells, Proteintech Group SIX2 antibody (Proteintech, 11562-1-AP) was used in immunocytochemistry on mouse samples at 1:200 (fig 8a). PLoS ONE (2016) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; rat; 1:500; fig s13
Proteintech Group SIX2 antibody (Proteintech, 11562-1-AP) was used in immunohistochemistry on rat samples at 1:500 (fig s13). Sci Rep (2016) ncbi
domestic rabbit polyclonal
Proteintech Group SIX2 antibody (Proteintech, 11562-1-AP) was used . PLoS ONE (2015) ncbi
domestic rabbit polyclonal
In order to evaluate the kidney organoids from human iPS cells, Proteintech Group SIX2 antibody (Proteintech, 11562-1-AP) was used . Nature (2015) ncbi
domestic rabbit polyclonal
Proteintech Group SIX2 antibody (Proteintech, 11562-1-AP) was used . Development (2015) ncbi
Abnova
mouse monoclonal (3D7)
  • immunohistochemistry; mouse; loading ...; fig 1f
Abnova SIX2 antibody (Abnova, H00010736-M01) was used in immunohistochemistry on mouse samples (fig 1f). elife (2019) ncbi
mouse monoclonal (3D7)
  • immunocytochemistry; human; 1:100; tbl 1
Abnova SIX2 antibody (Abnova, H00010736-M01) was used in immunocytochemistry on human samples at 1:100 (tbl 1). PLoS ONE (2015) ncbi
mouse monoclonal (3D7)
  • immunohistochemistry - paraffin section; mouse; 1:100
In order to study kidney development in Robo2 mouse mutants, Abnova SIX2 antibody (Abnova, H00010736-M01) was used in immunohistochemistry - paraffin section on mouse samples at 1:100. Dev Biol (2015) ncbi
mouse monoclonal (3D7)
  • immunohistochemistry - paraffin section; mouse; 1:100
In order to investigate the role of Mdm2 in the nephrogenic niche, Abnova SIX2 antibody (Abnova, H00010736-M01) was used in immunohistochemistry - paraffin section on mouse samples at 1:100. Dev Biol (2014) ncbi
Santa Cruz Biotechnology
mouse monoclonal (H-4)
  • immunohistochemistry - frozen section; mouse
In order to study the development of renal vasculature and the role played by Tbx18, Santa Cruz Biotechnology SIX2 antibody (Santa Cruz, sc377193) was used in immunohistochemistry - frozen section on mouse samples . Dev Biol (2014) ncbi
MilliporeSigma
domestic rabbit polyclonal
  • ChIP-Seq; rat; fig 6
  • immunohistochemistry; rat; fig 9
  • western blot; rat; fig 9
MilliporeSigma SIX2 antibody (Sigma, SAB2103006) was used in ChIP-Seq on rat samples (fig 6), in immunohistochemistry on rat samples (fig 9) and in western blot on rat samples (fig 9). Cell Death Dis (2016) ncbi
Articles Reviewed
  1. Calandrini C, Schutgens F, Oka R, Margaritis T, Candelli T, Mathijsen L, et al. An organoid biobank for childhood kidney cancers that captures disease and tissue heterogeneity. Nat Commun. 2020;11:1310 pubmed publisher
  2. Liu Z, Mar K, Hanners N, Perelman S, Kanchwala M, Xing C, et al. A NIK-SIX signalling axis controls inflammation by targeted silencing of non-canonical NF-κB. Nature. 2019;: pubmed publisher
  3. Lawlor K, Zappia L, Lefevre J, Park J, Hamilton N, Oshlack A, et al. Nephron progenitor commitment is a stochastic process influenced by cell migration. elife. 2019;8: pubmed publisher
  4. Hsieh W, Ramadesikan S, FEKETE D, Aguilar R. Kidney-differentiated cells derived from Lowe Syndrome patient's iPSCs show ciliogenesis defects and Six2 retention at the Golgi complex. PLoS ONE. 2018;13:e0192635 pubmed publisher
  5. Reginensi A, Enderle L, Gregorieff A, Johnson R, Wrana J, McNeill H. A critical role for NF2 and the Hippo pathway in branching morphogenesis. Nat Commun. 2016;7:12309 pubmed publisher
  6. Xu J, Liu H, Chai O, Lan Y, Jiang R. Osr1 Interacts Synergistically with Wt1 to Regulate Kidney Organogenesis. PLoS ONE. 2016;11:e0159597 pubmed publisher
  7. Dauleh S, Santeramo I, Fielding C, Ward K, Herrmann A, Murray P, et al. Characterisation of Cultured Mesothelial Cells Derived from the Murine Adult Omentum. PLoS ONE. 2016;11:e0158997 pubmed publisher
  8. Kirita Y, Kami D, Ishida R, Adachi T, Tamagaki K, Matoba S, et al. Preserved Nephrogenesis Following Partial Nephrectomy in Early Neonates. Sci Rep. 2016;6:26792 pubmed publisher
  9. Gao J, Kang X, Sun S, Li L, Zhang B, Li Y, et al. Transcription factor Six2 mediates the protection of GDNF on 6-OHDA lesioned dopaminergic neurons by regulating Smurf1 expression. Cell Death Dis. 2016;7:e2217 pubmed publisher
  10. Batchelder C, Martinez M, Tarantal A. Natural Scaffolds for Renal Differentiation of Human Embryonic Stem Cells for Kidney Tissue Engineering. PLoS ONE. 2015;10:e0143849 pubmed publisher
  11. Takasato M, Er P, Chiu H, Maier B, Baillie G, Ferguson C, et al. Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis. Nature. 2015;526:564-8 pubmed publisher
  12. Monteiro Carvalho Mori da Cunha M, Zia S, Oliveira Arcolino F, Carlon M, Beckmann D, Pippi N, et al. Amniotic Fluid Derived Stem Cells with a Renal Progenitor Phenotype Inhibit Interstitial Fibrosis in Renal Ischemia and Reperfusion Injury in Rats. PLoS ONE. 2015;10:e0136145 pubmed publisher
  13. Wainwright E, Wilhelm D, Combes A, Little M, Koopman P. ROBO2 restricts the nephrogenic field and regulates Wolffian duct-nephrogenic cord separation. Dev Biol. 2015;404:88-102 pubmed publisher
  14. Kann M, Bae E, Lenz M, Li L, Trannguyen B, Schumacher V, et al. WT1 targets Gas1 to maintain nephron progenitor cells by modulating FGF signals. Development. 2015;142:1254-66 pubmed publisher
  15. Xu J, Nie X, Cai X, Cai C, Xu P. Tbx18 is essential for normal development of vasculature network and glomerular mesangium in the mammalian kidney. Dev Biol. 2014;391:17-31 pubmed publisher
  16. Hilliard S, Yao X, El Dahr S. Mdm2 is required for maintenance of the nephrogenic niche. Dev Biol. 2014;387:1-14 pubmed publisher