This is a Validated Antibody Database (VAD) review about human SIRT7, based on 10 published articles (read how Labome selects the articles), using SIRT7 antibody in all methods. It is aimed to help Labome visitors find the most suited SIRT7 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
SIRT7 synonym: SIR2L7

Knockout validation
Santa Cruz Biotechnology
mouse monoclonal (C-3)
  • immunoprecipitation; human; loading ...; fig 2b
  • western blot; human; loading ...; fig 3a
  • western blot knockout validation; mouse; loading ...; fig 2e
Santa Cruz Biotechnology SIRT7 antibody (SantaCruz, sc-365344) was used in immunoprecipitation on human samples (fig 2b), in western blot on human samples (fig 3a) and in western blot knockout validation on mouse samples (fig 2e). Cell Rep (2017) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D3K5A)
  • immunohistochemistry knockout validation; mouse; 1:300; loading ...; fig 1c
  • western blot knockout validation; mouse; loading ...; fig 1a
  • western blot; rat; loading ...; fig 5a
Cell Signaling Technology SIRT7 antibody (Cell Signaling, 5360) was used in immunohistochemistry knockout validation on mouse samples at 1:300 (fig 1c), in western blot knockout validation on mouse samples (fig 1a) and in western blot on rat samples (fig 5a). Sci Rep (2018) ncbi
Santa Cruz Biotechnology
mouse monoclonal (C-3)
  • western blot; mouse; loading ...; fig 4d
Santa Cruz Biotechnology SIRT7 antibody (Santa Cruz, sc-365344) was used in western blot on mouse samples (fig 4d). Nat Commun (2021) ncbi
mouse monoclonal (C-3)
  • immunoprecipitation; human; loading ...; fig 2b
  • western blot; human; loading ...; fig 3a
  • western blot knockout validation; mouse; loading ...; fig 2e
Santa Cruz Biotechnology SIRT7 antibody (SantaCruz, sc-365344) was used in immunoprecipitation on human samples (fig 2b), in western blot on human samples (fig 3a) and in western blot knockout validation on mouse samples (fig 2e). Cell Rep (2017) ncbi
mouse monoclonal (C-3)
  • immunocytochemistry; human; 1:100; fig 4
  • western blot; human; 1:500; fig 1
Santa Cruz Biotechnology SIRT7 antibody (Santa Cruz, sc-365344) was used in immunocytochemistry on human samples at 1:100 (fig 4) and in western blot on human samples at 1:500 (fig 1). Nat Commun (2016) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D3K5A)
  • western blot; human; 1:1000; loading ...
Cell Signaling Technology SIRT7 antibody (Cell Signaling Technology, 5360) was used in western blot on human samples at 1:1000. Sci Adv (2021) ncbi
domestic rabbit monoclonal (D3K5A)
  • immunohistochemistry; rat; loading ...; fig 4k
  • western blot; rat; 1:1000; loading ...; fig 4h
Cell Signaling Technology SIRT7 antibody (Cell Signaling Technology, 5360S) was used in immunohistochemistry on rat samples (fig 4k) and in western blot on rat samples at 1:1000 (fig 4h). Signal Transduct Target Ther (2021) ncbi
domestic rabbit monoclonal (D3K5A)
  • immunohistochemistry knockout validation; mouse; 1:300; loading ...; fig 1c
  • western blot knockout validation; mouse; loading ...; fig 1a
  • western blot; rat; loading ...; fig 5a
Cell Signaling Technology SIRT7 antibody (Cell Signaling, 5360) was used in immunohistochemistry knockout validation on mouse samples at 1:300 (fig 1c), in western blot knockout validation on mouse samples (fig 1a) and in western blot on rat samples (fig 5a). Sci Rep (2018) ncbi
domestic rabbit monoclonal (D3K5A)
  • immunoprecipitation; human; loading ...; fig 2a
  • western blot; human; loading ...; fig 5i
Cell Signaling Technology SIRT7 antibody (Cell Signaling, D3K5A) was used in immunoprecipitation on human samples (fig 2a) and in western blot on human samples (fig 5i). Oncogene (2017) ncbi
domestic rabbit monoclonal (D3K5A)
  • immunocytochemistry; human; loading ...; fig 2b
  • western blot; human; loading ...; fig 1a
Cell Signaling Technology SIRT7 antibody (Cell Signaling, 5360) was used in immunocytochemistry on human samples (fig 2b) and in western blot on human samples (fig 1a). Nucleic Acids Res (2016) ncbi
domestic rabbit monoclonal (D3K5A)
  • western blot; mouse; 1:1000; fig 5
Cell Signaling Technology SIRT7 antibody (Cell Signaling, 5360) was used in western blot on mouse samples at 1:1000 (fig 5). Nat Commun (2015) ncbi
domestic rabbit monoclonal (D3K5A)
  • western blot; human; 1:250
In order to determine if curcumin can diminish/prevent the development of cardiovascular pathologies, Cell Signaling Technology SIRT7 antibody (Cell Signaling Technology, 9787) was used in western blot on human samples at 1:250. Toxicol Lett (2015) ncbi
Articles Reviewed
  1. Tang X, Li G, Shi L, Su F, Qian M, Liu Z, et al. Combined intermittent fasting and ERK inhibition enhance the anti-tumor effects of chemotherapy via the GSK3β-SIRT7 axis. Nat Commun. 2021;12:5058 pubmed publisher
  2. Shi X, Jiang Y, Kitano A, Hu T, Murdaugh R, Li Y, et al. Nuclear NAD+ homeostasis governed by NMNAT1 prevents apoptosis of acute myeloid leukemia stem cells. Sci Adv. 2021;7: pubmed publisher
  3. Xu S, Tao H, Cao W, Cao L, Lin Y, Zhao S, et al. Ketogenic diets inhibit mitochondrial biogenesis and induce cardiac fibrosis. Signal Transduct Target Ther. 2021;6:54 pubmed publisher
  4. Miyasato Y, Yoshizawa T, Sato Y, Nakagawa T, Miyasato Y, Kakizoe Y, et al. Sirtuin 7 Deficiency Ameliorates Cisplatin-induced Acute Kidney Injury Through Regulation of the Inflammatory Response. Sci Rep. 2018;8:5927 pubmed publisher
  5. Yu J, Qin B, Wu F, Qin S, Nowsheen S, Shan S, et al. Regulation of Serine-Threonine Kinase Akt Activation by NAD+-Dependent Deacetylase SIRT7. Cell Rep. 2017;18:1229-1240 pubmed publisher
  6. Li Z, Bridges B, Olson J, Weinman S. The interaction between acetylation and serine-574 phosphorylation regulates the apoptotic function of FOXO3. Oncogene. 2017;36:1887-1898 pubmed publisher
  7. Li L, Shi L, Yang S, Yan R, Zhang D, Yang J, et al. SIRT7 is a histone desuccinylase that functionally links to chromatin compaction and genome stability. Nat Commun. 2016;7:12235 pubmed publisher
  8. Zhang P, Li G, Deng Z, Liu L, Chen L, Tang J, et al. Dicer interacts with SIRT7 and regulates H3K18 deacetylation in response to DNA damaging agents. Nucleic Acids Res. 2016;44:3629-42 pubmed publisher
  9. Xiao X, Shi X, Fan Y, Zhang X, Wu M, Lan P, et al. GITR subverts Foxp3(+) Tregs to boost Th9 immunity through regulation of histone acetylation. Nat Commun. 2015;6:8266 pubmed publisher
  10. Lewinska A, Wnuk M, Grabowska W, Zabek T, Semik E, Sikora E, et al. Curcumin induces oxidation-dependent cell cycle arrest mediated by SIRT7 inhibition of rDNA transcription in human aortic smooth muscle cells. Toxicol Lett. 2015;233:227-38 pubmed publisher