This is a Validated Antibody Database (VAD) review about human SHP-2, based on 41 published articles (read how Labome selects the articles), using SHP-2 antibody in all methods. It is aimed to help Labome visitors find the most suited SHP-2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
SHP-2 synonym: BPTP3; CFC; JMML; METCDS; NS1; PTP-1D; PTP2C; SH-PTP2; SH-PTP3; SHP2
Knockout validation
Santa Cruz Biotechnology mouse monoclonal (B-1) |
| Santa Cruz Biotechnology SHP-2 antibody (Santa Cruz, sc-7384) was used in western blot knockout validation on mouse samples at 1:500 (fig 1c), in immunohistochemistry on mouse samples (fig 4a) and in western blot on human samples (fig 1e). Nat Commun (2017) ncbi |
Cell Signaling Technology domestic rabbit monoclonal (D50F2) |
| Cell Signaling Technology SHP-2 antibody (Cell Signaling, 3397) was used in immunohistochemistry - paraffin section on human samples at 1:200 (fig s1a), in western blot on human samples , in immunohistochemistry knockout validation on mouse samples at 1:200 (fig s2a) and in immunohistochemistry - paraffin section on mouse samples at 1:200 (fig s2a, s2d). Nat Med (2018) ncbi |
Santa Cruz Biotechnology
mouse monoclonal (B-1) |
| Santa Cruz Biotechnology SHP-2 antibody (Santa Cruz, sc-7384) was used in immunoprecipitation on human samples . elife (2021) ncbi |
mouse monoclonal (B-1) |
| Santa Cruz Biotechnology SHP-2 antibody (Santa Cruz Biotechnology, sc-7384) was used in western blot on human samples at 1:1000 (fig 2d). Nature (2020) ncbi |
mouse monoclonal (NS1-23-1) |
| Santa Cruz Biotechnology SHP-2 antibody (Santa, sc-130568) was used in western blot on Alphainfluenzavirus samples at 1:1000 (fig 1a). Nat Commun (2019) ncbi |
mouse monoclonal (B-1) |
| Santa Cruz Biotechnology SHP-2 antibody (Santa Cruz, sc-7384) was used in western blot on mouse samples at 1:500 (fig 7g). Front Immunol (2018) ncbi |
mouse monoclonal (B-1) |
| Santa Cruz Biotechnology SHP-2 antibody (Santa Cruz, sc-7384) was used in western blot knockout validation on mouse samples at 1:500 (fig 1c), in immunohistochemistry on mouse samples (fig 4a) and in western blot on human samples (fig 1e). Nat Commun (2017) ncbi |
mouse monoclonal (NS1-23-1) | In order to elucidate the interactions between zinc finger antiviral protein and influenza A virus, Santa Cruz Biotechnology SHP-2 antibody (Santa Cruz, sc-130568) was used . J Virol (2017) ncbi | |
mouse monoclonal (B-1) |
| Santa Cruz Biotechnology SHP-2 antibody (SantaCruz, sc-7384) was used in western blot on human samples (fig 4b). Mol Cell Biol (2016) ncbi |
mouse monoclonal (B-1) |
| Santa Cruz Biotechnology SHP-2 antibody (Santa Cruz, B-1) was used in immunohistochemistry - paraffin section on mouse samples at 1:1000 (fig s7c). Nat Commun (2016) ncbi |
mouse monoclonal (B-1) |
| Santa Cruz Biotechnology SHP-2 antibody (Santa Cruz Biotechnology, sc-7384) was used in western blot on human samples (fig 1Bb). J Cell Mol Med (2015) ncbi |
mouse monoclonal (B-1) |
| In order to study the role of Src homology phosphotyrosyl phosphatase 2 (SHP2) in triple negative breast cancers, Santa Cruz Biotechnology SHP-2 antibody (Santa Cruz Biotechnology, SC-7384) was used in western blot on human samples . BMC Cancer (2015) ncbi |
mouse monoclonal (NS1-23-1) |
| In order to study cell tropism and virus spread in vivo is with an influenza virus expressing a reporter gene, Santa Cruz Biotechnology SHP-2 antibody (Santa Cruz Biotechnology, sc-130568) was used in western blot on Alphainfluenzavirus samples . PLoS ONE (2015) ncbi |
mouse monoclonal (NS1-23-1) |
| Santa Cruz Biotechnology SHP-2 antibody (Santa Cruz, sc-130568) was used in western blot on Alphainfluenzavirus samples . J Virol (2015) ncbi |
mouse monoclonal (B-1) |
| Santa Cruz Biotechnology SHP-2 antibody (Santa Cruz Biotechnology, sc-7384) was used in western blot on human samples . Proteomics (2015) ncbi |
mouse monoclonal (NS1-23-1) | Santa Cruz Biotechnology SHP-2 antibody (Santa Cruz, sc-130568) was used . Virus Res (2014) ncbi | |
mouse monoclonal (B-1) |
| Santa Cruz Biotechnology SHP-2 antibody (Santa Cruz, sc-7384) was used in western blot on human samples . J Biol Chem (2013) ncbi |
mouse monoclonal (NS1-23-1) |
| Santa Cruz Biotechnology SHP-2 antibody (Santa Cruz, sc-130568) was used in western blot on Alphainfluenzavirus samples at 1:2000. PLoS ONE (2012) ncbi |
Abcam
domestic rabbit polyclonal |
| Abcam SHP-2 antibody (Abcam, ab75818) was used in western blot on human samples (fig s3f). (2022) ncbi |
domestic rabbit monoclonal (EP508(2)Y) |
| Abcam SHP-2 antibody (Abcam, ab62322) was used in western blot on human samples at 1:1000 (fig 2d). Nature (2020) ncbi |
domestic rabbit monoclonal (EP508(2)Y) |
| Abcam SHP-2 antibody (Abcam, ab62322) was used in western blot on human samples (fig e11-7b). Nature (2019) ncbi |
domestic rabbit monoclonal (EP508(2)Y) |
| Abcam SHP-2 antibody (Abcam, ab62322) was used in immunohistochemistry - paraffin section on mouse samples at 1:500 (fig s14f, s15g) and in immunohistochemistry - paraffin section on human samples at 1:500 (fig s17b). Nat Med (2018) ncbi |
domestic rabbit monoclonal (EP508(2)Y) |
| Abcam SHP-2 antibody (Abcam, ab62322) was used in western blot on human samples at 1:500 (fig 4b). Nat Commun (2017) ncbi |
domestic rabbit monoclonal (Y478) |
| Abcam SHP-2 antibody (Abcam, ab32083) was used in immunoprecipitation on human samples (fig 5e) and in western blot on human samples (fig 6e). Nat Genet (2016) ncbi |
Invitrogen
domestic rabbit polyclonal | In order to identify host signaling dynamics upon Burkholderia spp. infection by a reverse-phase protein microarray-based screen, Invitrogen SHP-2 antibody (BioSource, 44-558) was used . Front Microbiol (2015) ncbi |
Cell Signaling Technology
domestic rabbit monoclonal (D50F2) |
| Cell Signaling Technology SHP-2 antibody (Cell Signaling Technology, 3397) was used in western blot on human samples at 1:500 (fig 5d). elife (2021) ncbi |
domestic rabbit monoclonal (D50F2) |
| Cell Signaling Technology SHP-2 antibody (Cell Signaling, 3397) was used in western blot on mouse samples at 1:1000 (fig s9a) and in western blot on human samples at 1:1000 (fig s2f). Sci Rep (2021) ncbi |
domestic rabbit polyclonal |
| Cell Signaling Technology SHP-2 antibody (Cell Signaling, 3752) was used in western blot on human samples (fig 5c). Sci Adv (2020) ncbi |
domestic rabbit polyclonal |
| Cell Signaling Technology SHP-2 antibody (Cell Signaling, 3752) was used in western blot on human samples (fig s1f). Cell (2019) ncbi |
domestic rabbit polyclonal |
| Cell Signaling Technology SHP-2 antibody (Cell signaling technology, 3752) was used in western blot on human samples (fig 5a). Cell Rep (2019) ncbi |
domestic rabbit polyclonal |
| Cell Signaling Technology SHP-2 antibody (cell Signaling, 3703) was used in western blot on human samples at 1:500. Nature (2018) ncbi |
monoclonal (D66F10) |
| Cell Signaling Technology SHP-2 antibody (Cell Signaling, 13328S) was used in flow cytometry on human samples at 1:100. Nature (2018) ncbi |
domestic rabbit monoclonal (D50F2) |
| Cell Signaling Technology SHP-2 antibody (cell Signaling, 3397) was used in western blot on human samples at 1:1000. Nature (2018) ncbi |
domestic rabbit monoclonal (D50F2) |
| Cell Signaling Technology SHP-2 antibody (Cell Signaling, 3397) was used in immunohistochemistry - paraffin section on human samples at 1:200 (fig s1a), in western blot on human samples , in immunohistochemistry knockout validation on mouse samples at 1:200 (fig s2a) and in immunohistochemistry - paraffin section on mouse samples at 1:200 (fig s2a, s2d). Nat Med (2018) ncbi |
domestic rabbit polyclonal |
| Cell Signaling Technology SHP-2 antibody (Cell Signaling, 3751) was used in other on human samples (fig 4c). Cancer Cell (2018) ncbi |
domestic rabbit monoclonal (D50F2) |
| Cell Signaling Technology SHP-2 antibody (Cell Signaling, 3397T) was used in western blot on mouse samples (fig s5d). J Clin Invest (2017) ncbi |
domestic rabbit polyclonal |
| Cell Signaling Technology SHP-2 antibody (Cell Signaling, 3751T) was used in western blot on mouse samples (fig s5d). J Clin Invest (2017) ncbi |
domestic rabbit monoclonal (D50F2) |
| In order to report that CEACAM1 regulates the epithelial-mesenchymal transition via beta-catenin phosphorylation, Cell Signaling Technology SHP-2 antibody (Cell Signaling Technology, 3397S) was used in western blot on mouse samples at 1:1000 (fig 6a). Oncotarget (2016) ncbi |
domestic rabbit monoclonal (D50F2) |
| Cell Signaling Technology SHP-2 antibody (Cell Signaling Technology, 3397) was used in western blot on mouse samples (fig 2f). J Exp Med (2016) ncbi |
domestic rabbit monoclonal (D50F2) |
| Cell Signaling Technology SHP-2 antibody (Cell Signaling, 3397) was used in western blot on mouse samples at 1:1000 (fig 1). Nat Commun (2016) ncbi |
domestic rabbit polyclonal |
| In order to study a novel crizotinib-resistant solvent-front mutation in a patient with ROS1-rearranged lung cancer that is responsive to cabozantinib therapy, Cell Signaling Technology SHP-2 antibody (Cell signaling, 3703) was used in western blot on mouse samples at 1:1000 (fig 3). Clin Cancer Res (2016) ncbi |
domestic rabbit monoclonal (D50F2) |
| Cell Signaling Technology SHP-2 antibody (Cell Signaling Technology, 3397) was used in other on mouse samples (fig 6g), in proximity ligation assay on mouse samples (fig 6j) and in western blot on human samples at 1:1000 (fig S6a). Nat Commun (2015) ncbi |
domestic rabbit monoclonal (D66F10) |
| In order to study phosphorylation events at sites of adhesion, Cell Signaling Technology SHP-2 antibody (Cell Signaling Technology, 5431S) was used in western blot on mouse samples at 1:1000 (fig 4). Nat Commun (2015) ncbi |
domestic rabbit monoclonal (D50F2) |
| Cell Signaling Technology SHP-2 antibody (Cell Signaling, 3397) was used in western blot on human samples . Am J Physiol Renal Physiol (2013) ncbi |
BD Biosciences
mouse monoclonal (79/PTP1D/SHP2) |
| BD Biosciences SHP-2 antibody (BD, 79) was used in western blot on human samples (fig 5a). J Exp Med (2019) ncbi |
mouse monoclonal (79/PTP1D/SHP2) |
| BD Biosciences SHP-2 antibody (BD, 610621) was used in western blot on human samples (fig 5c). J Biol Chem (2017) ncbi |
mouse monoclonal (79/PTP1D/SHP2) |
| BD Biosciences SHP-2 antibody (BD Biosciences, 610622) was used in western blot on mouse samples (fig 8b) and in western blot on human samples (fig 5b). Redox Biol (2017) ncbi |
mouse monoclonal (79/PTP1D/SHP2) |
| BD Biosciences SHP-2 antibody (BD Biosciences, 610622) was used in immunoprecipitation on mouse samples at 1:100 (fig 1e) and in western blot on mouse samples at 1:1000 (fig 1c). JCI Insight (2016) ncbi |
mouse monoclonal (79/PTP1D/SHP2) |
| In order to examine the contribution of the Lhx9-integrin-paxillin pathway to proepicardial organ positioning and epicardial formation, BD Biosciences SHP-2 antibody (BD Transduction, 610622) was used in western blot on Xenopus laevis samples at 1:2500. Development (2016) ncbi |
mouse monoclonal (79/PTP1D/SHP2) |
| In order to investigate the role of cardiac transcription factor CASTOR (CASZ1) in heart development, BD Biosciences SHP-2 antibody (BD Transduction Laboratories, 610622) was used in western blot on Xenopus laevis samples (fig s12). Development (2014) ncbi |
Articles Reviewed
- Sauer M, Herbst J, Diekmann U, Rudd C, Kardinal C. SHP-1 Acts as a Key Regulator of Alloresponses by Modulating LFA-1-Mediated Adhesion in Primary Murine T Cells. Mol Cell Biol. 2016;36:3113-3127 pubmed
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