This is a Validated Antibody Database (VAD) review about human SGPL1, based on 3 published articles (read how Labome selects the articles), using SGPL1 antibody in all methods. It is aimed to help Labome visitors find the most suited SGPL1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
SGPL1 synonym: NPHS14; S1PL; SPL; sphingosine-1-phosphate lyase 1; SP-lyase 1; SPL 1; hSPL; sphingosine-1-phosphate aldolase

R&D Systems
goat polyclonal
  • western blot; rat; loading ...; fig 3c
  • immunohistochemistry; mouse; loading ...; fig 2a
  • immunocytochemistry; human; loading ...; fig 2m
  • western blot; human; loading ...; fig 2k
In order to perform whole exome sequencing to identify recessive causes of steroid-resistant nephrotic syndrome, R&D Systems SGPL1 antibody (R&D Systems, AF5535) was used in western blot on rat samples (fig 3c), in immunohistochemistry on mouse samples (fig 2a), in immunocytochemistry on human samples (fig 2m) and in western blot on human samples (fig 2k). J Clin Invest (2017) ncbi
goat polyclonal
  • western blot; human; 1 ug/ml
R&D Systems SGPL1 antibody (R&D Systems, AF5535) was used in western blot on human samples at 1 ug/ml. Lipids Health Dis (2014) ncbi
Abcam
rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:200; loading ...; fig 3e
  • western blot; human; 1:1000; loading ...; fig 3c
Abcam SGPL1 antibody (Abcam, 105183) was used in immunohistochemistry - paraffin section on human samples at 1:200 (fig 3e) and in western blot on human samples at 1:1000 (fig 3c). J Clin Invest (2017) ncbi
Articles Reviewed
  1. Prasad R, Hadjidemetriou I, Maharaj A, Meimaridou E, Buonocore F, Saleem M, et al. Sphingosine-1-phosphate lyase mutations cause primary adrenal insufficiency and steroid-resistant nephrotic syndrome. J Clin Invest. 2017;127:942-953 pubmed publisher
  2. Lovric S, Gonçalves S, Gee H, Oskouian B, Srinivas H, Choi W, et al. Mutations in sphingosine-1-phosphate lyase cause nephrosis with ichthyosis and adrenal insufficiency. J Clin Invest. 2017;127:912-928 pubmed publisher
  3. Abu El Asrar A, Nawaz M, Mohammad G, Siddiquei M, Alam K, Mousa A, et al. Expression of bioactive lysophospholipids and processing enzymes in the vitreous from patients with proliferative diabetic retinopathy. Lipids Health Dis. 2014;13:187 pubmed publisher