This is a Validated Antibody Database (VAD) review about human SGO1, based on 5 published articles (read how Labome selects the articles), using SGO1 antibody in all methods. It is aimed to help Labome visitors find the most suited SGO1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
SGO1 synonym: CAID; NY-BR-85; SGO; SGOL1; shugoshin 1; serologically defined breast cancer antigen NY-BR-85; shugoshin 1AB protein; shugoshin 1CD protein; shugoshin 1EF protein; shugoshin 1GH protein; shugoshin 1KL protein

Abnova
mouse monoclonal (3C11)
  • immunocytochemistry; human; 1:100
Abnova SGO1 antibody (Abnova, H00151648-M01) was used in immunocytochemistry on human samples at 1:100. elife (2015) ncbi
mouse monoclonal (3C11)
  • immunocytochemistry; human; fig 2
In order to elucidate the regulation and dynamics of H2A-T120 phosphorylation by Bub1, Abnova SGO1 antibody (Abnova, H00151648-M01) was used in immunocytochemistry on human samples (fig 2). Nat Commun (2015) ncbi
mouse monoclonal (3C11)
  • immunocytochemistry; human; 1:2000
In order to investigate the regulation of SAC primes kinetochore phosphatases, Abnova SGO1 antibody (Abnova, H00151648-M01) was used in immunocytochemistry on human samples at 1:2000. Nat Cell Biol (2014) ncbi
Proteintech Group
rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1.0 ug/ml
In order to assess the use of mitotic error-induced CIN and Shugoshin1 haplo insufficient mice as models to study chromosome instability in colon cancer, Proteintech Group SGO1 antibody (Proteintech, 16977-1-AP) was used in immunohistochemistry - paraffin section on mouse samples at 1.0 ug/ml. Mol Carcinog (2016) ncbi
Invitrogen
rabbit polyclonal
  • western blot; human; 1:1000
In order to study the role of separase at centrosomes, Invitrogen SGO1 antibody (Thermo Scientific, PA5-30869) was used in western blot on human samples at 1:1000. PLoS Genet (2014) ncbi
Articles Reviewed
  1. Zielinska A, Holubcová Z, Blayney M, Elder K, Schuh M. Sister kinetochore splitting and precocious disintegration of bivalents could explain the maternal age effect. elife. 2015;4:e11389 pubmed publisher
  2. Asghar A, Lajeunesse A, Dulla K, Combes G, Thebault P, Nigg E, et al. Bub1 autophosphorylation feeds back to regulate kinetochore docking and promote localized substrate phosphorylation. Nat Commun. 2015;6:8364 pubmed publisher
  3. Rao C, Sanghera S, Zhang Y, Biddick L, Reddy A, Lightfoot S, et al. Antagonizing pathways leading to differential dynamics in colon carcinogenesis in Shugoshin1 (Sgo1)-haploinsufficient chromosome instability model. Mol Carcinog. 2016;55:600-10 pubmed publisher
  4. Nijenhuis W, Vallardi G, Teixeira A, Kops G, Saurin A. Negative feedback at kinetochores underlies a responsive spindle checkpoint signal. Nat Cell Biol. 2014;16:1257-64 pubmed publisher
  5. Agircan F, Schiebel E. Sensors at centrosomes reveal determinants of local separase activity. PLoS Genet. 2014;10:e1004672 pubmed publisher