This is a Validated Antibody Database (VAD) review about human SGK3, based on 6 published articles (read how Labome selects the articles), using SGK3 antibody in all methods. It is aimed to help Labome visitors find the most suited SGK3 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
SGK3 synonym: CISK; SGK2; SGKL; serine/threonine-protein kinase Sgk3; cytokine-independent survival kinase

Knockout validation
Cell Signaling Technology
rabbit monoclonal (D18D1)
  • western blot; Rhesus monkey; loading ...; fig 7h
  • western blot knockout validation; mouse; loading ...; fig s7b
Cell Signaling Technology SGK3 antibody (Cell Signaling, 8156) was used in western blot on Rhesus monkey samples (fig 7h) and in western blot knockout validation on mouse samples (fig s7b). Cell (2019) ncbi
Santa Cruz Biotechnology
mouse monoclonal (C-6)
  • western blot; human; fig 1
Santa Cruz Biotechnology SGK3 antibody (Santa Cruz, sc-166847) was used in western blot on human samples (fig 1). PLoS ONE (2015) ncbi
Cell Signaling Technology
rabbit monoclonal (D42C2)
  • immunoprecipitation; human; loading ...; fig 3a
  • western blot; human; 1:1000; loading ...; fig 3b
Cell Signaling Technology SGK3 antibody (Cell Signaling, 8573) was used in immunoprecipitation on human samples (fig 3a) and in western blot on human samples at 1:1000 (fig 3b). Int J Biol Sci (2019) ncbi
rabbit monoclonal (D30E6)
  • western blot; human; 1:500; loading ...; fig 3b
Cell Signaling Technology SGK3 antibody (Cell Signaling, 5642) was used in western blot on human samples at 1:500 (fig 3b). Int J Biol Sci (2019) ncbi
rabbit monoclonal (D18D1)
  • western blot; Rhesus monkey; loading ...; fig 7h
  • western blot knockout validation; mouse; loading ...; fig s7b
Cell Signaling Technology SGK3 antibody (Cell Signaling, 8156) was used in western blot on Rhesus monkey samples (fig 7h) and in western blot knockout validation on mouse samples (fig s7b). Cell (2019) ncbi
rabbit monoclonal (D30E6)
  • western blot; human; loading ...; fig 4a
Cell Signaling Technology SGK3 antibody (Cell signaling, 5642) was used in western blot on human samples (fig 4a). Oncotarget (2016) ncbi
rabbit monoclonal (D18D1)
  • western blot; mouse; fig s2a
  • immunoprecipitation; human; fig s2c
  • western blot; human; fig s1
Cell Signaling Technology SGK3 antibody (Cell Signaling Technologies, 8156) was used in western blot on mouse samples (fig s2a), in immunoprecipitation on human samples (fig s2c) and in western blot on human samples (fig s1). Mol Cell (2014) ncbi
rabbit monoclonal (D30E6)
  • western blot; human; fig 8a
Cell Signaling Technology SGK3 antibody (Cell signaling, D30E6) was used in western blot on human samples (fig 8a). J Biol Chem (2014) ncbi
Articles Reviewed
  1. Wang H, Huang F, Zhang Z, Wang P, Luo Y, Li H, et al. Feedback Activation of SGK3 and AKT Contributes to Rapamycin Resistance by Reactivating mTORC1/4EBP1 Axis via TSC2 in Breast Cancer. Int J Biol Sci. 2019;15:929-941 pubmed publisher
  2. Zhou B, Kreuzer J, Kumsta C, Wu L, Kamer K, Cedillo L, et al. Mitochondrial Permeability Uncouples Elevated Autophagy and Lifespan Extension. Cell. 2019;177:299-314.e16 pubmed publisher
  3. Kong X, Liu F, Gao J. MiR-155 promotes epithelial-mesenchymal transition in hepatocellular carcinoma cells through the activation of PI3K/SGK3/β-catenin signaling pathways. Oncotarget. 2016;7:66051-66060 pubmed publisher
  4. Hausmann S, Brandt E, Köchel C, Einsele H, Bargou R, Seggewiss Bernhardt R, et al. Loss of serum and glucocorticoid-regulated kinase 3 (SGK3) does not affect proliferation and survival of multiple myeloma cell lines. PLoS ONE. 2015;10:e0122689 pubmed publisher
  5. Gasser J, Inuzuka H, Lau A, Wei W, Beroukhim R, Toker A. SGK3 mediates INPP4B-dependent PI3K signaling in breast cancer. Mol Cell. 2014;56:595-607 pubmed publisher
  6. Wang Y, Xu W, Zhou D, Neckers L, Chen S. Coordinated regulation of serum- and glucocorticoid-inducible kinase 3 by a C-terminal hydrophobic motif and Hsp90-Cdc37 chaperone complex. J Biol Chem. 2014;289:4815-26 pubmed publisher