This is a Validated Antibody Database (VAD) review about human SGK1, based on 15 published articles (read how Labome selects the articles), using SGK1 antibody in all methods. It is aimed to help Labome visitors find the most suited SGK1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
SGK1 synonym: SGK

Knockout validation
Cell Signaling Technology
domestic rabbit monoclonal (D27C11)
  • western blot knockout validation; mouse; loading ...; fig 4b, 1i
  • western blot; rhesus macaque; loading ...; fig 4b, 1i
Cell Signaling Technology SGK1 antibody (Cell Signaling, 12103) was used in western blot knockout validation on mouse samples (fig 4b, 1i) and in western blot on rhesus macaque samples (fig 4b, 1i). Cell (2019) ncbi
Abcam
domestic rabbit monoclonal (Y238)
  • immunohistochemistry - paraffin section; human; 1:200; loading ...; fig 1d
Abcam SGK1 antibody (Abcam, Y238) was used in immunohistochemistry - paraffin section on human samples at 1:200 (fig 1d). BMC Cancer (2020) ncbi
domestic rabbit monoclonal (Y238)
  • immunohistochemistry; mouse; 1:1000; loading ...; fig 5a
  • western blot; mouse; 1:1000; loading ...; fig 6a
In order to show that serum- and glucocorticoid-inducible kinase-1 governs the glucocorticoid-enhanced release of ATP from astrocytes, Abcam SGK1 antibody (Abcam, ab32374) was used in immunohistochemistry on mouse samples at 1:1000 (fig 5a) and in western blot on mouse samples at 1:1000 (fig 6a). Nat Commun (2016) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; 1:100; fig 4
  • western blot; mouse; 1:1000; fig 2
Abcam SGK1 antibody (Abcam, ab59337) was used in immunohistochemistry - frozen section on mouse samples at 1:100 (fig 4) and in western blot on mouse samples at 1:1000 (fig 2). Exp Mol Med (2016) ncbi
Santa Cruz Biotechnology
mouse monoclonal (H-4)
  • western blot; mouse; fig 5a
Santa Cruz Biotechnology SGK1 antibody (Santa Cruz, sc-28338) was used in western blot on mouse samples (fig 5a). Sci Rep (2016) ncbi
mouse monoclonal (H-4)
  • western blot; rat; 1 ug/ml; fig 6
Santa Cruz Biotechnology SGK1 antibody (santa Cruz, sc-28338) was used in western blot on rat samples at 1 ug/ml (fig 6). Front Cell Neurosci (2015) ncbi
mouse monoclonal (G-4)
  • western blot; human; 1:250; fig 1,2,3,4,5,6,7
In order to show that Che-1 inhibits mTOR activity in response to stress conditions, Santa Cruz Biotechnology SGK1 antibody (Santa Cruz, sc-377360) was used in western blot on human samples at 1:250 (fig 1,2,3,4,5,6,7). EMBO J (2015) ncbi
mouse monoclonal (H-4)
  • western blot; rat; 1:200
Santa Cruz Biotechnology SGK1 antibody (Santa Cruz Biotechnology, sc-28338) was used in western blot on rat samples at 1:200. Can J Cardiol (2014) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D27C11)
  • western blot knockout validation; mouse; loading ...; fig 4b, 1i
  • western blot; rhesus macaque; loading ...; fig 4b, 1i
Cell Signaling Technology SGK1 antibody (Cell Signaling, 12103) was used in western blot knockout validation on mouse samples (fig 4b, 1i) and in western blot on rhesus macaque samples (fig 4b, 1i). Cell (2019) ncbi
domestic rabbit monoclonal (D27C11)
  • western blot; human; loading ...; fig 7d
Cell Signaling Technology SGK1 antibody (Cell Signaling Technology, 12103) was used in western blot on human samples (fig 7d). J Clin Invest (2019) ncbi
domestic rabbit monoclonal (D36D11)
  • western blot; human; loading ...; fig 7d
Cell Signaling Technology SGK1 antibody (Cell Signaling Technology, 5599) was used in western blot on human samples (fig 7d). J Clin Invest (2019) ncbi
domestic rabbit monoclonal (D36D11)
  • western blot; mouse; loading ...; fig 4b
Cell Signaling Technology SGK1 antibody (CST, 5599) was used in western blot on mouse samples (fig 4b). Proc Natl Acad Sci U S A (2018) ncbi
domestic rabbit monoclonal (D27C11)
  • western blot; mouse; loading ...; fig 4b
Cell Signaling Technology SGK1 antibody (CST, 12103) was used in western blot on mouse samples (fig 4b). Proc Natl Acad Sci U S A (2018) ncbi
domestic rabbit monoclonal (D27C11)
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 1h
  • western blot; human; 1:1000; loading ...; fig 1b
Cell Signaling Technology SGK1 antibody (Cell Signaling, 12103) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 1h) and in western blot on human samples at 1:1000 (fig 1b). J Clin Invest (2018) ncbi
domestic rabbit monoclonal (D27C11)
  • western blot; human; loading ...; fig 8a
Cell Signaling Technology SGK1 antibody (Cell Signaling, D27C11) was used in western blot on human samples (fig 8a). J Virol (2018) ncbi
domestic rabbit monoclonal (D36D11)
  • western blot; human; loading ...; fig 2b
Cell Signaling Technology SGK1 antibody (Cell Signaling, 5599) was used in western blot on human samples (fig 2b). Oncotarget (2017) ncbi
domestic rabbit monoclonal (D27C11)
  • western blot; human; loading ...; fig 2b
Cell Signaling Technology SGK1 antibody (Cell Signaling, 12103) was used in western blot on human samples (fig 2b). Oncotarget (2017) ncbi
domestic rabbit monoclonal (D27C11)
  • western blot; human; 1:1000; fig 2
Cell Signaling Technology SGK1 antibody (Cell signalling, #12103) was used in western blot on human samples at 1:1000 (fig 2). Cell Mol Gastroenterol Hepatol (2016) ncbi
domestic rabbit monoclonal (D36D11)
  • western blot; mouse
Cell Signaling Technology SGK1 antibody (Cell Signaling Technology, 5599) was used in western blot on mouse samples . J Neurochem (2015) ncbi
Articles Reviewed
  1. Ueki S, Fujishima F, Kumagai T, Ishida H, Okamoto H, Takaya K, et al. GR, Sgk1, and NDRG1 in esophageal squamous cell carcinoma: their correlation with therapeutic outcome of neoadjuvant chemotherapy. BMC Cancer. 2020;20:161 pubmed publisher
  2. Zhou B, Kreuzer J, Kumsta C, Wu L, Kamer K, Cedillo L, et al. Mitochondrial Permeability Uncouples Elevated Autophagy and Lifespan Extension. Cell. 2019;177:299-314.e16 pubmed publisher
  3. Wang W, Shen T, Dong B, Creighton C, Meng Y, Zhou W, et al. MAPK4 overexpression promotes tumor progression via noncanonical activation of AKT/mTOR signaling. J Clin Invest. 2019;: pubmed publisher
  4. Du X, de Almeida P, Manieri N, de Almeida Nagata D, Wu T, Harden Bowles K, et al. CD226 regulates natural killer cell antitumor responses via phosphorylation-mediated inactivation of transcription factor FOXO1. Proc Natl Acad Sci U S A. 2018;115:E11731-E11740 pubmed publisher
  5. Voelkl J, Luong T, Tuffaha R, Musculus K, Auer T, Lian X, et al. SGK1 induces vascular smooth muscle cell calcification through NF-κB signaling. J Clin Invest. 2018;128:3024-3040 pubmed publisher
  6. Schweitzer C, Zhang F, Boyer A, Valdez K, Cam M, Liang T. N-Myc Downstream-Regulated Gene 1 Restricts Hepatitis C Virus Propagation by Regulating Lipid Droplet Biogenesis and Viral Assembly. J Virol. 2018;92: pubmed publisher
  7. Sakre N, Wildey G, Behtaj M, Kresak A, Yang M, Fu P, et al. RICTOR amplification identifies a subgroup in small cell lung cancer and predicts response to drugs targeting mTOR. Oncotarget. 2017;8:5992-6002 pubmed publisher
  8. Koyanagi S, Kusunose N, Taniguchi M, Akamine T, Kanado Y, Ozono Y, et al. Glucocorticoid regulation of ATP release from spinal astrocytes underlies diurnal exacerbation of neuropathic mechanical allodynia. Nat Commun. 2016;7:13102 pubmed publisher
  9. Kim S, Kim H, Kim C. GLCCI1 is a novel component associated with the PI3K signaling pathway in podocyte foot processes. Exp Mol Med. 2016;48:e233 pubmed publisher
  10. Yu H, Yang T, Gao P, Wei X, Zhang H, Xiong S, et al. Caffeine intake antagonizes salt sensitive hypertension through improvement of renal sodium handling. Sci Rep. 2016;6:25746 pubmed publisher
  11. Cipriani G, Gibbons S, Verhulst P, Choi K, Eisenman S, Hein S, et al. Diabetic Csf1op/op mice lacking macrophages are protected against the development of delayed gastric emptying. Cell Mol Gastroenterol Hepatol. 2016;2:40-47 pubmed
  12. Matschke V, Theiss C, Hollmann M, Schulze Bahr E, Lang F, Seebohm G, et al. NDRG2 phosphorylation provides negative feedback for SGK1-dependent regulation of a kainate receptor in astrocytes. Front Cell Neurosci. 2015;9:387 pubmed publisher
  13. Desantis A, Bruno T, Catena V, De Nicola F, Goeman F, Iezzi S, et al. Che-1-induced inhibition of mTOR pathway enables stress-induced autophagy. EMBO J. 2015;34:1214-30 pubmed publisher
  14. Heller E, Kaska S, Fallon B, Ferguson D, Kennedy P, Neve R, et al. Morphine and cocaine increase serum- and glucocorticoid-inducible kinase 1 activity in the ventral tegmental area. J Neurochem. 2015;132:243-53 pubmed publisher
  15. Cong B, Wang L, Zhu X, Li X, Liu B, Ni X. SGK1 is involved in cardioprotection of urocortin-1 against hypoxia/reoxygenation in cardiomyocytes. Can J Cardiol. 2014;30:687-95 pubmed publisher