This is a Validated Antibody Database (VAD) review about human SFRP1, based on 11 published articles (read how Labome selects the articles), using SFRP1 antibody in all methods. It is aimed to help Labome visitors find the most suited SFRP1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
SFRP1 synonym: FRP; FRP-1; FRP1; FrzA; SARP2; secreted frizzled-related protein 1; SARP-2; frizzled-related protein; sFRP-1; secreted apoptosis-related protein 2

Abcam
rabbit polyclonal
  • western blot; mouse; loading ...; fig 2b
In order to show that decreased WNT/beta-catenin contributes to the pathophysiology of lamin A/C gene cardiomyopathy, Abcam SFRP1 antibody (Abcam, ab4193) was used in western blot on mouse samples (fig 2b). Hum Mol Genet (2017) ncbi
rabbit monoclonal (EPR7003)
  • western blot; human; loading ...; fig s10c
In order to discuss how signal peptidase complex proteins affect flaviviruses, Abcam SFRP1 antibody (Abcam, ab126613) was used in western blot on human samples (fig s10c). Nature (2016) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:200; fig 1
In order to develop a CRISPR/Cas9-mediated method for somatic gene disruption, Abcam SFRP1 antibody (Abcam, ab4193) was used in immunohistochemistry - paraffin section on mouse samples at 1:200 (fig 1). Nat Commun (2015) ncbi
rabbit monoclonal (EPR7003)
  • immunohistochemistry - paraffin section; human; loading ...; fig 2a
  • western blot; human; loading ...; fig 3a
Abcam SFRP1 antibody (Abcam, ab126613) was used in immunohistochemistry - paraffin section on human samples (fig 2a) and in western blot on human samples (fig 3a). PLoS ONE (2015) ncbi
rabbit monoclonal (EPR7003)
  • western blot; human
Abcam SFRP1 antibody (Abcam, ab126613) was used in western blot on human samples . Cell Div (2014) ncbi
rabbit monoclonal (EPR7003)
  • western blot; human
Abcam SFRP1 antibody (Epitomics, 5467-1) was used in western blot on human samples . Oncogene (2015) ncbi
rabbit polyclonal
  • immunohistochemistry; human; 1:200
Abcam SFRP1 antibody (Abcam, ab4193) was used in immunohistochemistry on human samples at 1:200. Stem Cells (2013) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:800
In order to characterize osteoblastic and osteolytic proteins in prostate cancer bone metastases, Abcam SFRP1 antibody (Abcam, Ab4193) was used in immunohistochemistry - paraffin section on human samples at 1:800. Prostate (2013) ncbi
R&D Systems
goat polyclonal
  • ELISA; human; fig 2
R&D Systems SFRP1 antibody (R&D Systems, AF1384) was used in ELISA on human samples (fig 2). PLoS ONE (2015) ncbi
Cell Signaling Technology
rabbit monoclonal (D5A7)
  • western blot; human; 1:500; loading ...; fig s5g
In order to report that cell density deterministically alters anteroposterior patterning of primitive streak-like priming, Cell Signaling Technology SFRP1 antibody (Cell signaling, D5A7) was used in western blot on human samples at 1:500 (fig s5g). Nat Commun (2016) ncbi
rabbit monoclonal (D5A7)
  • immunocytochemistry; human; 1:100
  • immunohistochemistry; human
  • western blot; human; 1:250
In order to determine the prognostic role of the Wnt-signaling antagonist SFRP1 in bladder cancer, Cell Signaling Technology SFRP1 antibody (Cell Signaling, D5A7) was used in immunocytochemistry on human samples at 1:100, in immunohistochemistry on human samples and in western blot on human samples at 1:250. J Cancer Res Clin Oncol (2015) ncbi
Articles Reviewed
  1. Le Dour C, Macquart C, Sera F, Homma S, Bonne G, Morrow J, et al. Decreased WNT/?-catenin signalling contributes to the pathogenesis of dilated cardiomyopathy caused by mutations in the lamin a/C gene. Hum Mol Genet. 2017;26:333-343 pubmed publisher
  2. Kempf H, Olmer R, Haase A, Franke A, Bolesani E, Schwanke K, et al. Bulk cell density and Wnt/TGFbeta signalling regulate mesendodermal patterning of human pluripotent stem cells. Nat Commun. 2016;7:13602 pubmed publisher
  3. Zhang R, Miner J, Gorman M, Rausch K, Ramage H, White J, et al. A CRISPR screen defines a signal peptide processing pathway required by flaviviruses. Nature. 2016;535:164-8 pubmed
  4. Schummer M, Thorpe J, Giraldez M, Giraldez M, Bergan L, Tewari M, et al. Evaluating Serum Markers for Hormone Receptor-Negative Breast Cancer. PLoS ONE. 2015;10:e0142911 pubmed publisher
  5. Zuckermann M, Hovestadt V, Knobbe Thomsen C, Zapatka M, Northcott P, Schramm K, et al. Somatic CRISPR/Cas9-mediated tumour suppressor disruption enables versatile brain tumour modelling. Nat Commun. 2015;6:7391 pubmed publisher
  6. Rogler A, Kendziorra E, Giedl J, Stoehr C, Taubert H, Goebell P, et al. Functional analyses and prognostic significance of SFRP1 expression in bladder cancer. J Cancer Res Clin Oncol. 2015;141:1779-90 pubmed publisher
  7. Zheng L, Sun D, Fan W, Zhang Z, Li Q, Jiang T. Diagnostic value of SFRP1 as a favorable predictive and prognostic biomarker in patients with prostate cancer. PLoS ONE. 2015;10:e0118276 pubmed publisher
  8. Lee M, Marina M, King J, Saavedra H. Differential expression of centrosome regulators in Her2+ breast cancer cells versus non-tumorigenic MCF10A cells. Cell Div. 2014;9:3 pubmed publisher
  9. Cyr A, Kulak M, Park J, Bogachek M, Spanheimer P, Woodfield G, et al. TFAP2C governs the luminal epithelial phenotype in mammary development and carcinogenesis. Oncogene. 2015;34:436-44 pubmed publisher
  10. Manoranjan B, Wang X, Hallett R, Venugopal C, Mack S, McFarlane N, et al. FoxG1 interacts with Bmi1 to regulate self-renewal and tumorigenicity of medulloblastoma stem cells. Stem Cells. 2013;31:1266-77 pubmed publisher
  11. Larson S, Zhang X, Dumpit R, Coleman I, Lakely B, Roudier M, et al. Characterization of osteoblastic and osteolytic proteins in prostate cancer bone metastases. Prostate. 2013;73:932-40 pubmed publisher