This is a Validated Antibody Database (VAD) review about human SET, based on 7 published articles (read how Labome selects the articles), using SET antibody in all methods. It is aimed to help Labome visitors find the most suited SET antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
SET synonym: 2PP2A; I2PP2A; IGAAD; IPP2A2; PHAPII; TAF-I; TAF-IBETA; protein SET; HLA-DR-associated protein II; SET nuclear oncogene; SET translocation (myeloid leukemia-associated); Template-Activating Factor-I, chromatin remodelling factor; inhibitor of granzyme A-activated DNase; inhibitor-2 of protein phosphatase-2A; phosphatase 2A inhibitor I2PP2A; protein phosphatase type 2A inhibitor

Knockout validation
Santa Cruz Biotechnology
mouse monoclonal (F-9)
  • western blot knockout validation; mouse; loading ...; fig 4j
  • chromatin immunoprecipitation; human; loading ...; fig 1i
  • western blot; human; loading ...; fig s4a
Santa Cruz Biotechnology SET antibody (Santa Cruz, Sc-133138) was used in western blot knockout validation on mouse samples (fig 4j), in chromatin immunoprecipitation on human samples (fig 1i) and in western blot on human samples (fig s4a). Nature (2016) ncbi
Santa Cruz Biotechnology
mouse monoclonal (F-9)
  • western blot; human; loading ...; fig 6a
Santa Cruz Biotechnology SET antibody (Santa Cruz, sc-133138) was used in western blot on human samples (fig 6a). Oncotarget (2017) ncbi
mouse monoclonal (F-9)
  • western blot knockout validation; mouse; loading ...; fig 4j
  • chromatin immunoprecipitation; human; loading ...; fig 1i
  • western blot; human; loading ...; fig s4a
Santa Cruz Biotechnology SET antibody (Santa Cruz, Sc-133138) was used in western blot knockout validation on mouse samples (fig 4j), in chromatin immunoprecipitation on human samples (fig 1i) and in western blot on human samples (fig s4a). Nature (2016) ncbi
Abcam
rabbit polyclonal
  • immunocytochemistry; human; 1:200; loading ...; fig 3a
  • western blot; human; 1:2000; fig 3b
Abcam SET antibody (Abcam, 1183) was used in immunocytochemistry on human samples at 1:200 (fig 3a) and in western blot on human samples at 1:2000 (fig 3b). Epigenetics Chromatin (2015) ncbi
rabbit monoclonal (EPR12973)
  • western blot; human; fig s2
Abcam SET antibody (Abcam, ab181990) was used in western blot on human samples (fig s2). Nature (2015) ncbi
rabbit polyclonal
  • western blot; dog
Abcam SET antibody (Abcam, ab1183) was used in western blot on dog samples . J Vet Med Sci (2014) ncbi
Bethyl
rabbit polyclonal
  • immunohistochemistry; mouse; loading ...; fig 4b
Bethyl SET antibody (Bethyl Labs, A302-261A) was used in immunohistochemistry on mouse samples (fig 4b). Cell Death Dis (2019) ncbi
rabbit polyclonal
  • immunohistochemistry; human; fig 1
  • western blot; human; fig 3
  • immunohistochemistry; mouse; fig 2
Bethyl SET antibody (Bethyl, A302-261A) was used in immunohistochemistry on human samples (fig 1), in western blot on human samples (fig 3) and in immunohistochemistry on mouse samples (fig 2). Sci Rep (2015) ncbi
Sigma-Aldrich
mouse monoclonal (SET51)
  • chromatin immunoprecipitation; human; loading ...; fig 1i
Sigma-Aldrich SET antibody (Sigma, SAB4200479) was used in chromatin immunoprecipitation on human samples (fig 1i). Nature (2016) ncbi
Articles Reviewed
  1. Kon N, Wang D, Gu W. Loss of SET reveals both the p53-dependent and the p53-independent functions in vivo. Cell Death Dis. 2019;10:237 pubmed publisher
  2. Almeida L, Neto M, Sousa L, Tannous M, Curti C, Leopoldino A. SET oncoprotein accumulation regulates transcription through DNA demethylation and histone hypoacetylation. Oncotarget. 2017;8:26802-26818 pubmed publisher
  3. Wang D, Kon N, Lasso G, Jiang L, Leng W, Zhu W, et al. Acetylation-regulated interaction between p53 and SET reveals a widespread regulatory mode. Nature. 2016;538:118-122 pubmed publisher
  4. Hu X, Garcia C, Fazli L, Gleave M, Vitek M, Jansen M, et al. Inhibition of Pten deficient Castration Resistant Prostate Cancer by Targeting of the SET - PP2A Signaling axis. Sci Rep. 2015;5:15182 pubmed publisher
  5. Zhang Q, Giebler H, Isaacson M, Nyborg J. Eviction of linker histone H1 by NAP-family histone chaperones enhances activated transcription. Epigenetics Chromatin. 2015;8:30 pubmed publisher
  6. Berkovits B, Mayr C. Alternative 3' UTRs act as scaffolds to regulate membrane protein localization. Nature. 2015;522:363-7 pubmed publisher
  7. Yabe R, Fujiwara N, Mizuno T, Usui T, Ohama T, Sato K. Characterization of SET/I2PP2A isoforms in dogs. J Vet Med Sci. 2014;76:1235-40 pubmed