This is a Validated Antibody Database (VAD) review about human SENP1, based on 14 published articles (read how Labome selects the articles), using SENP1 antibody in all methods. It is aimed to help Labome visitors find the most suited SENP1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
SENP1 synonym: SuPr-2

Knockout validation
Abcam
domestic rabbit polyclonal
  • immunocytochemistry knockout validation; mouse; loading ...; fig 2d
  • western blot; mouse; loading ...; fig 2b
Abcam SENP1 antibody (Abcam, ab236094) was used in immunocytochemistry knockout validation on mouse samples (fig 2d) and in western blot on mouse samples (fig 2b). Aging (Albany NY) (2021) ncbi
Abcam
domestic rabbit monoclonal (EPR3844)
  • immunohistochemistry knockout validation; mouse; loading ...; fig 2h
Abcam SENP1 antibody (Abcam, Ab108981) was used in immunohistochemistry knockout validation on mouse samples (fig 2h). Cell Rep (2019) ncbi
Abcam
domestic rabbit monoclonal (EPR3844)
  • western blot knockout validation; mouse; 1:1000; loading ...; fig s2a
  • western blot; human; 1:1000; loading ...; fig 6f
In order to study the involvement of SENP1-mediated GATA2 deSUMOylation in graft arteriosclerosis, Abcam SENP1 antibody (Abcam, ab108981) was used in western blot knockout validation on mouse samples at 1:1000 (fig s2a) and in western blot on human samples at 1:1000 (fig 6f). Nat Commun (2017) ncbi
Abcam
domestic rabbit monoclonal (EPR3844)
  • western blot; human; loading ...; fig 4j
Abcam SENP1 antibody (Abcam, ab108981) was used in western blot on human samples (fig 4j). J Clin Invest (2022) ncbi
domestic rabbit monoclonal (EPR3844)
  • immunohistochemistry; mouse; loading ...; fig 6e
  • western blot; mouse; loading ...; fig 6e
  • immunohistochemistry; human; loading ...; fig 1a
  • western blot; human; loading ...; fig 6g
Abcam SENP1 antibody (Abcam, ab108981) was used in immunohistochemistry on mouse samples (fig 6e), in western blot on mouse samples (fig 6e), in immunohistochemistry on human samples (fig 1a) and in western blot on human samples (fig 6g). Cell Death Discov (2021) ncbi
domestic rabbit polyclonal
  • immunocytochemistry knockout validation; mouse; loading ...; fig 2d
  • western blot; mouse; loading ...; fig 2b
Abcam SENP1 antibody (Abcam, ab236094) was used in immunocytochemistry knockout validation on mouse samples (fig 2d) and in western blot on mouse samples (fig 2b). Aging (Albany NY) (2021) ncbi
domestic rabbit monoclonal (EPR3844)
  • immunohistochemistry knockout validation; mouse; loading ...; fig 2h
Abcam SENP1 antibody (Abcam, Ab108981) was used in immunohistochemistry knockout validation on mouse samples (fig 2h). Cell Rep (2019) ncbi
domestic rabbit monoclonal (EPR3844)
  • western blot; human; loading ...; fig s4b
Abcam SENP1 antibody (Abcam, ab108981) was used in western blot on human samples (fig s4b). Cell Rep (2019) ncbi
domestic rabbit monoclonal (EPR3844)
  • chromatin immunoprecipitation; human; fig 3b
  • western blot; human; fig 3c
Abcam SENP1 antibody (Abcam, ab108981) was used in chromatin immunoprecipitation on human samples (fig 3b) and in western blot on human samples (fig 3c). J Biol Chem (2018) ncbi
domestic rabbit monoclonal (EPR3844)
  • western blot knockout validation; mouse; 1:1000; loading ...; fig s2a
  • western blot; human; 1:1000; loading ...; fig 6f
In order to study the involvement of SENP1-mediated GATA2 deSUMOylation in graft arteriosclerosis, Abcam SENP1 antibody (Abcam, ab108981) was used in western blot knockout validation on mouse samples at 1:1000 (fig s2a) and in western blot on human samples at 1:1000 (fig 6f). Nat Commun (2017) ncbi
domestic rabbit monoclonal (EPR3844)
  • western blot; human; loading ...; fig 2c
Abcam SENP1 antibody (abcam, ab108981) was used in western blot on human samples (fig 2c). Oncotarget (2016) ncbi
domestic rabbit monoclonal (EPR3844)
  • western blot; human; 1:5000; fig 4a
Abcam SENP1 antibody (Abcam, ab108981) was used in western blot on human samples at 1:5000 (fig 4a). J Biol Chem (2016) ncbi
domestic rabbit monoclonal (EPR3844)
  • western blot; human; loading ...; fig s1
Abcam SENP1 antibody (Abcam, ab108981) was used in western blot on human samples (fig s1). Nat Commun (2015) ncbi
Santa Cruz Biotechnology
mouse monoclonal (C-12)
  • western blot; mouse; 1:500
Santa Cruz Biotechnology SENP1 antibody (Santa, sc-271360) was used in western blot on mouse samples at 1:500. J Clin Invest (2015) ncbi
mouse monoclonal (C-12)
  • immunocytochemistry; human; fig s5
  • western blot; human; 1:1000; fig 5
In order to determine the role of DBC1 sumoylation in p53-mediated apoptosis, Santa Cruz Biotechnology SENP1 antibody (Santa Cruz Biotechnology, clone C-12) was used in immunocytochemistry on human samples (fig s5) and in western blot on human samples at 1:1000 (fig 5). Nat Commun (2014) ncbi
mouse monoclonal (C-12)
  • western blot; human
Santa Cruz Biotechnology SENP1 antibody (Santa Cruz, sc-271360) was used in western blot on human samples . Mol Med Rep (2014) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D16D7)
  • western blot; human; 1:2000; loading ...; fig 5e
Cell Signaling Technology SENP1 antibody (Cell Signaling, 11929) was used in western blot on human samples at 1:2000 (fig 5e). Genes Dev (2017) ncbi
Articles Reviewed
  1. Luo Y, Li Z, Kong Y, He W, Zheng H, An M, et al. KRAS mutant-driven SUMOylation controls extracellular vesicle transmission to trigger lymphangiogenesis in pancreatic cancer. J Clin Invest. 2022;132: pubmed publisher
  2. Zhang Y, Ma Y, Wu G, Xie M, Luo C, Huang X, et al. SENP1 promotes MCL pathogenesis through regulating JAK-STAT5 pathway and SOCS2 expression. Cell Death Discov. 2021;7:192 pubmed publisher
  3. Wang H, Xiong W, Hang S, Wang Y, Zhang S, Liu S. Depletion of SENP1-mediated PPARγ SUMOylation exaggerates intermittent hypoxia-induced cognitive decline by aggravating microglia-mediated neuroinflammation. Aging (Albany NY). 2021;13:15240-15254 pubmed publisher
  4. Yin M, Zhou H, Lin C, Long L, Yang X, Zhang H, et al. CD34+KLF4+ Stromal Stem Cells Contribute to Endometrial Regeneration and Repair. Cell Rep. 2019;27:2709-2724.e3 pubmed publisher
  5. Liebelt F, Sebastian R, Moore C, Mulder M, Ovaa H, Shoulders M, et al. SUMOylation and the HSF1-Regulated Chaperone Network Converge to Promote Proteostasis in Response to Heat Shock. Cell Rep. 2019;26:236-249.e4 pubmed publisher
  6. Rodriguez Castaneda F, Lemma R, Cuervo I, Bengtsen M, Moen L, Ledsaak M, et al. The SUMO protease SENP1 and the chromatin remodeler CHD3 interact and jointly affect chromatin accessibility and gene expression. J Biol Chem. 2018;293:15439-15454 pubmed publisher
  7. Yue X, Zhang C, Zhao Y, Liu J, Lin A, Tan V, et al. Gain-of-function mutant p53 activates small GTPase Rac1 through SUMOylation to promote tumor progression. Genes Dev. 2017;31:1641-1654 pubmed publisher
  8. Qiu C, Wang Y, Zhao H, Qin L, Shi Y, Zhu X, et al. The critical role of SENP1-mediated GATA2 deSUMOylation in promoting endothelial activation in graft arteriosclerosis. Nat Commun. 2017;8:15426 pubmed publisher
  9. Wu J, Lei H, Zhang J, Chen X, Tang C, Wang W, et al. Momordin Ic, a new natural SENP1 inhibitor, inhibits prostate cancer cell proliferation. Oncotarget. 2016;7:58995-59005 pubmed publisher
  10. McLaughlin D, Coey C, Yang W, Drohat A, Matunis M. Characterizing Requirements for Small Ubiquitin-like Modifier (SUMO) Modification and Binding on Base Excision Repair Activity of Thymine-DNA Glycosylase in Vivo. J Biol Chem. 2016;291:9014-24 pubmed publisher
  11. Chen C, Zhu C, Huang J, Zhao X, Deng R, Zhang H, et al. SUMOylation of TARBP2 regulates miRNA/siRNA efficiency. Nat Commun. 2015;6:8899 pubmed publisher
  12. Ferdaoussi M, Dai X, Jensen M, Wang R, Peterson B, Huang C, et al. Isocitrate-to-SENP1 signaling amplifies insulin secretion and rescues dysfunctional β cells. J Clin Invest. 2015;125:3847-60 pubmed publisher
  13. Park J, Lee S, Yang S, Yoo H, Park J, Seong M, et al. Modification of DBC1 by SUMO2/3 is crucial for p53-mediated apoptosis in response to DNA damage. Nat Commun. 2014;5:5483 pubmed publisher
  14. Qin Y, Bao H, Pan Y, Yin M, Liu Y, Wu S, et al. SUMOylation alterations are associated with multidrug resistance in hepatocellular carcinoma. Mol Med Rep. 2014;9:877-81 pubmed publisher