This is a Validated Antibody Database (VAD) review about human SCNN1A, based on 6 published articles (read how Labome selects the articles), using SCNN1A antibody in all methods. It is aimed to help Labome visitors find the most suited SCNN1A antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
SCNN1A synonym: BESC2; ENaCa; ENaCalpha; SCNEA; SCNN1; amiloride-sensitive sodium channel subunit alpha; alpha ENaC-2; alpha-ENaC; alpha-NaCH; amiloride-sensitive epithelial sodium channel alpha subunit; amiloride-sensitive sodium channel subunit alpha 2; epithelial Na(+) channel subunit alpha; nasal epithelial sodium channel alpha subunit; nonvoltage-gated sodium channel 1 subunit alpha; sodium channel, non voltage gated 1 alpha subunit; sodium channel, non-voltage-gated 1 alpha; sodium channel, nonvoltage-gated 1 alpha

Invitrogen
rabbit polyclonal
  • western blot; human; loading ...; fig 5a
In order to elucidate the mechanisms of dexmedetomidine treatment on human alveolar fluid transport, Invitrogen SCNN1A antibody (Thermo Fisher, PA1-920A) was used in western blot on human samples (fig 5a). Fundam Clin Pharmacol (2017) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 3a
In order to investigate the effects of formaldehyde on epithelial sodium channels in vivo, Invitrogen SCNN1A antibody (Thermo Fisher, PA1-920A) was used in western blot on human samples at 1:1000 (fig 3a). Sci Rep (2016) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; fig s4
In order to test if GATA5 is a regulator of blood pressure, Invitrogen SCNN1A antibody (Pierce, PA1?C920A) was used in western blot on mouse samples at 1:1000 (fig s4). Nat Commun (2015) ncbi
rabbit polyclonal
  • immunohistochemistry; mouse; 1:800; fig 1
In order to study the epithelial Na(+) channel that transports and regulated mechanosensitive biliary epithelial transport, Invitrogen SCNN1A antibody (Thermo Fisher Scientific, PA1-920A) was used in immunohistochemistry on mouse samples at 1:800 (fig 1). Hepatology (2016) ncbi
rabbit polyclonal
  • western blot; mouse
In order to study the effects of ATRAP in the renal distal tubules in response to high salt treatment using wild type and ATRAP transgenic mice, Invitrogen SCNN1A antibody (Affinity Bioreagents, PA1-920A) was used in western blot on mouse samples . J Am Heart Assoc (2015) ncbi
Proteintech Group
rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:800
  • immunohistochemistry - paraffin section; mouse; 1:800
  • western blot; mouse; 1:1000
Proteintech Group SCNN1A antibody (Proteintech Group, 10924-2-AP) was used in immunohistochemistry - paraffin section on human samples at 1:800, in immunohistochemistry - paraffin section on mouse samples at 1:800 and in western blot on mouse samples at 1:1000. PLoS ONE (2014) ncbi
Articles Reviewed
  1. Cui Y, Ding Y, Chen L, Li Y, Li Y, Nie H. Dexmedetomidine enhances human lung fluid clearance through improving alveolar sodium transport. Fundam Clin Pharmacol. 2017;31:429-437 pubmed publisher
  2. Cui Y, Li H, Wu S, Zhao R, Du D, Ding Y, et al. Formaldehyde impairs transepithelial sodium transport. Sci Rep. 2016;6:35857 pubmed publisher
  3. Messaoudi S, He Y, Gutsol A, Wight A, Hébert R, Vilmundarson R, et al. Endothelial Gata5 transcription factor regulates blood pressure. Nat Commun. 2015;6:8835 pubmed publisher
  4. Li Q, Kresge C, Bugde A, Lamphere M, Park J, Feranchak A. Regulation of mechanosensitive biliary epithelial transport by the epithelial Na(+) channel. Hepatology. 2016;63:538-49 pubmed publisher
  5. Wakui H, Uneda K, Tamura K, Ohsawa M, Azushima K, Kobayashi R, et al. Renal tubule angiotensin II type 1 receptor-associated protein promotes natriuresis and inhibits salt-sensitive blood pressure elevation. J Am Heart Assoc. 2015;4:e001594 pubmed publisher
  6. Zhou M, Fu J, Huang W, Shen L, Xiao L, Song Y, et al. Increased cystic fibrosis transmembrane conductance regulators expression and decreased epithelial sodium channel alpha subunits expression in early abortion: findings from a mouse model and clinical cases of abortion. PLoS ONE. 2014;9:e99521 pubmed publisher