This is a Validated Antibody Database (VAD) review about human SAS 6, based on 16 published articles (read how Labome selects the articles), using SAS 6 antibody in all methods. It is aimed to help Labome visitors find the most suited SAS 6 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
SAS 6 synonym: MCPH14; SAS-6; SAS6

Knockout validation
Santa Cruz Biotechnology
mouse monoclonal (G-1)
  • western blot knockout validation; human; fig 1
Santa Cruz Biotechnology SAS 6 antibody (Santa Cruz Biotechnology, sc-376836) was used in western blot knockout validation on human samples (fig 1). elife (2015) ncbi
Santa Cruz Biotechnology
mouse monoclonal (91.390.21)
  • western blot knockout validation; human; fig 1
Santa Cruz Biotechnology SAS 6 antibody (Santa Cruz Biotechnology, sc-81431) was used in western blot knockout validation on human samples (fig 1). elife (2015) ncbi
Santa Cruz Biotechnology
mouse monoclonal (91.390.21)
  • immunocytochemistry; human; 1:200; loading ...; fig 6e
Santa Cruz Biotechnology SAS 6 antibody (Santa Cruz, sc-81431) was used in immunocytochemistry on human samples at 1:200 (fig 6e). elife (2019) ncbi
mouse monoclonal (91.390.21)
  • western blot; human; 1:500; loading ...; fig 6e
In order to demonstrate that Epstein-Barr virus infection of B-lymphocytes leads to an increased rate of centrosome amplification, Santa Cruz Biotechnology SAS 6 antibody (Santa Cruz, sc-81431) was used in western blot on human samples at 1:500 (fig 6e). Nat Commun (2017) ncbi
mouse monoclonal (91.390.21)
  • immunocytochemistry; human; 1:500; loading ...; fig 2e
In order to characterize the human lysine acetyltransferases KAT2A and KAT2B, Santa Cruz Biotechnology SAS 6 antibody (Santa Cruz, sc-81431) was used in immunocytochemistry on human samples at 1:500 (fig 2e). Nat Commun (2016) ncbi
mouse monoclonal (91.390.21)
  • immunocytochemistry; human; 1:300; fig s2
In order to learn regulation of actin network architecture and ciliogenesis due to STAR syndrome-associated CDK10/Cyclin M, Santa Cruz Biotechnology SAS 6 antibody (Santa Cruz, sc-81431) was used in immunocytochemistry on human samples at 1:300 (fig s2). Cell Cycle (2016) ncbi
mouse monoclonal (G-1)
  • western blot knockout validation; human; fig 1
Santa Cruz Biotechnology SAS 6 antibody (Santa Cruz Biotechnology, sc-376836) was used in western blot knockout validation on human samples (fig 1). elife (2015) ncbi
mouse monoclonal (91.390.21)
  • western blot knockout validation; human; fig 1
Santa Cruz Biotechnology SAS 6 antibody (Santa Cruz Biotechnology, sc-81431) was used in western blot knockout validation on human samples (fig 1). elife (2015) ncbi
mouse monoclonal (91.390.21)
  • immunocytochemistry; human; 1:200; fig 2
Santa Cruz Biotechnology SAS 6 antibody (Santa Cruz Biotechnology, sc-81431) was used in immunocytochemistry on human samples at 1:200 (fig 2). Mol Biol Cell (2015) ncbi
mouse monoclonal (91.390.21)
  • immunocytochemistry; human; 1:500; fig 3
  • western blot; human; 1:500; fig 6
Santa Cruz Biotechnology SAS 6 antibody (Santa Cruz, sc-81431) was used in immunocytochemistry on human samples at 1:500 (fig 3) and in western blot on human samples at 1:500 (fig 6). Nat Commun (2015) ncbi
mouse monoclonal (91.390.21)
  • immunocytochemistry; human; 1:100; fig 2
Santa Cruz Biotechnology SAS 6 antibody (Santa Cruz, sc-81431) was used in immunocytochemistry on human samples at 1:100 (fig 2). Nat Commun (2015) ncbi
mouse monoclonal (91.390.21)
  • immunocytochemistry; human
In order to investigate centrosome regulation during fever, Santa Cruz Biotechnology SAS 6 antibody (Santa Cruz Biotechnology, sc-81431) was used in immunocytochemistry on human samples . Mol Biol Cell (2015) ncbi
mouse monoclonal (91.390.21)
  • western blot; human; 1:1000; fig 1g
Santa Cruz Biotechnology SAS 6 antibody (Santa Cruz Biotechnology,, sc-81431) was used in western blot on human samples at 1:1000 (fig 1g). J Cell Biol (2015) ncbi
mouse monoclonal (91.390.21)
  • immunocytochemistry; human; fig s1
Santa Cruz Biotechnology SAS 6 antibody (Santa Cruz, sc-81431) was used in immunocytochemistry on human samples (fig s1). PLoS Genet (2015) ncbi
mouse monoclonal (91.390.21)
  • western blot; human; 1:1000
Santa Cruz Biotechnology SAS 6 antibody (Santa, sc-81431) was used in western blot on human samples at 1:1000. EMBO J (2015) ncbi
mouse monoclonal (91.390.21)
  • western blot; human; 1:1000
Santa Cruz Biotechnology SAS 6 antibody (Santa, sc-81431) was used in western blot on human samples at 1:1000. Nat Commun (2014) ncbi
mouse monoclonal (91.390.21)
  • immunohistochemistry; mouse; 1:500; fig 1
Santa Cruz Biotechnology SAS 6 antibody (Santa Cruz Biotechnology, sc-81431) was used in immunohistochemistry on mouse samples at 1:500 (fig 1). J Cell Biol (2014) ncbi
mouse monoclonal (91.390.21)
  • immunocytochemistry; human; 1:100
In order to examine centriole behavior after DNA damage in synchronized untransformed human cells, Santa Cruz Biotechnology SAS 6 antibody (Santa, sc-81431) was used in immunocytochemistry on human samples at 1:100. J Cell Physiol (2014) ncbi
mouse monoclonal (91.390.21)
  • western blot; human; fig 2
Santa Cruz Biotechnology SAS 6 antibody (Santa, 91.390.21) was used in western blot on human samples (fig 2). J Cell Sci (2014) ncbi
Articles Reviewed
  1. Moyer T, HOLLAND A. PLK4 promotes centriole duplication by phosphorylating STIL to link the procentriole cartwheel to the microtubule wall. elife. 2019;8: pubmed publisher
  2. Shumilov A, Tsai M, Schlosser Y, Kratz A, Bernhardt K, Fink S, et al. Epstein-Barr virus particles induce centrosome amplification and chromosomal instability. Nat Commun. 2017;8:14257 pubmed publisher
  3. Fournier M, Orpinell M, Grauffel C, Scheer E, Garnier J, Ye T, et al. KAT2A/KAT2B-targeted acetylome reveals a role for PLK4 acetylation in preventing centrosome amplification. Nat Commun. 2016;7:13227 pubmed publisher
  4. Guen V, Gamble C, Perez D, Bourassa S, Zappel H, Gartner J, et al. STAR syndrome-associated CDK10/Cyclin M regulates actin network architecture and ciliogenesis. Cell Cycle. 2016;15:678-88 pubmed publisher
  5. Wang W, Acehan D, Kao C, Jane W, Uryu K, Tsou M. De novo centriole formation in human cells is error-prone and does not require SAS-6 self-assembly. elife. 2015;4: pubmed publisher
  6. Van de Mark D, Kong D, Loncarek J, Stearns T. MDM1 is a microtubule-binding protein that negatively regulates centriole duplication. Mol Biol Cell. 2015;26:3788-802 pubmed publisher
  7. Shukla A, Kong D, Sharma M, Magidson V, Loncarek J. Plk1 relieves centriole block to reduplication by promoting daughter centriole maturation. Nat Commun. 2015;6:8077 pubmed publisher
  8. Kim S, Lee K, Choi J, Ringstad N, Dynlacht B. Nek2 activation of Kif24 ensures cilium disassembly during the cell cycle. Nat Commun. 2015;6:8087 pubmed publisher
  9. Vertii A, Zimmerman W, Ivshina M, Doxsey S. Centrosome-intrinsic mechanisms modulate centrosome integrity during fever. Mol Biol Cell. 2015;26:3451-63 pubmed publisher
  10. Moyer T, Clutario K, Lambrus B, Daggubati V, Holland A. Binding of STIL to Plk4 activates kinase activity to promote centriole assembly. J Cell Biol. 2015;209:863-78 pubmed publisher
  11. Panic M, Hata S, Neuner A, Schiebel E. The centrosomal linker and microtubules provide dual levels of spatial coordination of centrosomes. PLoS Genet. 2015;11:e1005243 pubmed publisher
  12. Shiratsuchi G, Takaoka K, Ashikawa T, Hamada H, Kitagawa D. RBM14 prevents assembly of centriolar protein complexes and maintains mitotic spindle integrity. EMBO J. 2015;34:97-114 pubmed publisher
  13. Ohta M, Ashikawa T, Nozaki Y, Kozuka Hata H, Goto H, Inagaki M, et al. Direct interaction of Plk4 with STIL ensures formation of a single procentriole per parental centriole. Nat Commun. 2014;5:5267 pubmed publisher
  14. Kong D, Farmer V, Shukla A, James J, Gruskin R, Kiriyama S, et al. Centriole maturation requires regulated Plk1 activity during two consecutive cell cycles. J Cell Biol. 2014;206:855-65 pubmed publisher
  15. Douthwright S, Sluder G. Link between DNA damage and centriole disengagement/reduplication in untransformed human cells. J Cell Physiol. 2014;229:1427-36 pubmed publisher
  16. Xu Q, Zhang Y, Xiong X, Huang Y, Salisbury J, Hu J, et al. PIPKI? targets to the centrosome and restrains centriole duplication. J Cell Sci. 2014;127:1293-305 pubmed publisher