This is a Validated Antibody Database (VAD) review about human RelB, based on 27 published articles (read how Labome selects the articles), using RelB antibody in all methods. It is aimed to help Labome visitors find the most suited RelB antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
RelB synonym: I-REL; IMD53; IREL; REL-B; transcription factor RelB; v-rel avian reticuloendotheliosis viral oncogene homolog B (nuclear factor of kappa light polypeptide gene enhancer in B-cells 3); v-rel reticuloendotheliosis viral oncogene homolog B, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3

Knockout validation
Cell Signaling Technology
rabbit polyclonal
  • western blot knockout validation; mouse; 1:500; fig s3h
Cell Signaling Technology RelB antibody (Cell Signaling Technology, 4954) was used in western blot knockout validation on mouse samples at 1:500 (fig s3h). Nat Cell Biol (2017) ncbi
Santa Cruz Biotechnology
mouse monoclonal (C-4)
  • flow cytometry; mouse; fig 5h
  • western blot; human; loading ...; fig 6d
Santa Cruz Biotechnology RelB antibody (Santa Cruz Biotechnology, SC-48379) was used in flow cytometry on mouse samples (fig 5h) and in western blot on human samples (fig 6d). J Exp Med (2018) ncbi
mouse monoclonal (D-4)
  • western blot; human; loading ...; fig 5a
In order to research the effect of VHL on immune response against renal cell carcinoma and its mechanism, Santa Cruz Biotechnology RelB antibody (Santa Cruz, sc-48366) was used in western blot on human samples (fig 5a). J Cell Biol (2017) ncbi
mouse monoclonal (D-4)
  • chromatin immunoprecipitation; mouse; loading ...; fig 3g
Santa Cruz Biotechnology RelB antibody (SantaCruz, sc-48366X) was used in chromatin immunoprecipitation on mouse samples (fig 3g). J Immunol (2017) ncbi
Abcam
rabbit monoclonal (EP613Y)
  • immunohistochemistry; human; 1:50; tbl 2
In order to evaluate the reliance on EBV or NF-kappaB signaling instead of B-cell receptor signaling in regards to complete phenotypic characterization of PTLD, Abcam RelB antibody (Abcam, ab33917) was used in immunohistochemistry on human samples at 1:50 (tbl 2). Hematol Oncol (2017) ncbi
Bethyl
rabbit polyclonal
  • chromatin immunoprecipitation; mouse; fig 9
Bethyl RelB antibody (Bethyl Laboratories, A302-183A) was used in chromatin immunoprecipitation on mouse samples (fig 9). Toxicol Sci (2015) ncbi
Cell Signaling Technology
rabbit monoclonal (C1E4)
  • western blot; human; loading ...; fig s8f
Cell Signaling Technology RelB antibody (Cell Signaling, 4922) was used in western blot on human samples (fig s8f). Science (2018) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 4f
Cell Signaling Technology RelB antibody (Cell Signaling Technology, 4954) was used in western blot on mouse samples (fig 4f). Nature (2018) ncbi
rabbit polyclonal
  • western blot knockout validation; mouse; 1:500; fig s3h
Cell Signaling Technology RelB antibody (Cell Signaling Technology, 4954) was used in western blot knockout validation on mouse samples at 1:500 (fig s3h). Nat Cell Biol (2017) ncbi
rabbit monoclonal (C1E4)
  • western blot; mouse; loading ...; fig 1a
In order to analyze 2 members of a novel class of NF-kB inhibitors in both mouse and golden retriever muscular dystrophy dog models of Duchenne muscular dystrophy, Cell Signaling Technology RelB antibody (Cell Signalling, 4922) was used in western blot on mouse samples (fig 1a). JCI Insight (2016) ncbi
rabbit monoclonal (C1E4)
  • western blot; human; loading ...; fig 5b
Cell Signaling Technology RelB antibody (cell signalling, 4922) was used in western blot on human samples (fig 5b). Breast Cancer Res (2016) ncbi
rabbit monoclonal (C1E4)
  • western blot; human; 1:1000; loading ...; fig s8c
In order to elucidate the role of NOTCH1 in oncogene-induced senescence, Cell Signaling Technology RelB antibody (Cell signaling, 4922) was used in western blot on human samples at 1:1000 (fig s8c). Nat Cell Biol (2016) ncbi
rabbit monoclonal (C1E4)
  • western blot; rat; 1:1000; loading ...; fig 9a
In order to examine the expression and localization of Rel/nuclear factor-KB proteins in renal tissue from polycystic kidney disease samples, Cell Signaling Technology RelB antibody (Cell Signaling, 4922) was used in western blot on rat samples at 1:1000 (fig 9a). World J Nephrol (2016) ncbi
rabbit monoclonal (C1E4)
  • western blot; human; 1:1000; fig 3
Cell Signaling Technology RelB antibody (Cell Signaling Technologies, 4922) was used in western blot on human samples at 1:1000 (fig 3). J Cell Sci (2016) ncbi
rabbit monoclonal (C1E4)
  • western blot; mouse; fig 6
In order to study how PDLIM1 suppresses NF-kappaB activation, Cell Signaling Technology RelB antibody (Cell Signaling Technology, 4922) was used in western blot on mouse samples (fig 6). Sci Rep (2015) ncbi
rabbit polyclonal
  • western blot; mouse; fig 1
Cell Signaling Technology RelB antibody (Cell Signaling, 4954) was used in western blot on mouse samples (fig 1). Oncogene (2016) ncbi
rabbit monoclonal (C1E4)
  • western blot; mouse; 1:1000; fig 3
Cell Signaling Technology RelB antibody (Cell Signaling, 4922) was used in western blot on mouse samples at 1:1000 (fig 3). Nat Commun (2015) ncbi
rabbit monoclonal (C1E4)
  • chromatin immunoprecipitation; human; fig 6d
Cell Signaling Technology RelB antibody (Cell signaling, 4922) was used in chromatin immunoprecipitation on human samples (fig 6d). Oncotarget (2015) ncbi
rabbit polyclonal
  • western blot; human; fig 1
In order to report that NF-kappaB2 and RelB have multiple effects on the expression of key regulators of the cell cycle, reactive oxygen species generation, and protein stability, Cell Signaling Technology RelB antibody (Cell signaling, 4954S) was used in western blot on human samples (fig 1). PLoS Genet (2014) ncbi
rabbit monoclonal (C1E4)
  • western blot; mouse; fig 3
In order to show that RIPK1 regulates homeostasis and prevents inflammation in barrier tissues by inhibiting epithelial cell apoptosis and necroptosis, Cell Signaling Technology RelB antibody (Cell Signaling, 4922) was used in western blot on mouse samples (fig 3). Nature (2014) ncbi
rabbit monoclonal (C1E4)
  • western blot; human; loading ...; fig s4
Cell Signaling Technology RelB antibody (Cell Signaling, 4922) was used in western blot on human samples (fig s4). PLoS ONE (2014) ncbi
rabbit monoclonal (C1E4)
  • immunoprecipitation; human
  • western blot; human
Cell Signaling Technology RelB antibody (Cell Signaling technology, 4922) was used in immunoprecipitation on human samples and in western blot on human samples . Biochem Biophys Res Commun (2014) ncbi
rabbit monoclonal (C1E4)
  • western blot; mouse
In order to study p65-dependent NF-kapaB signaling in keratinocytes and its contribution to skin carcinogenesis, Cell Signaling Technology RelB antibody (Cell signaling, 4922) was used in western blot on mouse samples . EMBO Mol Med (2014) ncbi
rabbit monoclonal (C1E4)
  • western blot; human; 1:1000; loading ...; fig 4b
Cell Signaling Technology RelB antibody (cell signalling, 4922) was used in western blot on human samples at 1:1000 (fig 4b). Nat Cell Biol (2014) ncbi
rabbit polyclonal
  • western blot; human
Cell Signaling Technology RelB antibody (Cell Signaling, 4954S) was used in western blot on human samples . Cell Cycle (2013) ncbi
rabbit monoclonal (C1E4)
  • western blot; human
Cell Signaling Technology RelB antibody (Cell Signalling Technology, C1E4) was used in western blot on human samples . PLoS ONE (2012) ncbi
rabbit monoclonal (C1E4)
  • western blot; mouse
In order to study the role of TNF in zVAD-induced necroptosis in L929 cells, Cell Signaling Technology RelB antibody (Cell Signaling, 4922) was used in western blot on mouse samples . Cell Death Differ (2011) ncbi
EMD Millipore
rabbit polyclonal
  • western blot; mouse; fig s7
In order to study hepatocellular carcinoma and ectopic lymphoid structures function as microniches for tumor progenitor cells, EMD Millipore RelB antibody (Milipore, 06-1105) was used in western blot on mouse samples (fig s7). Nat Immunol (2015) ncbi
Articles Reviewed
  1. Zhang J, Wu T, Simon J, Takada M, Saito R, Fan C, et al. VHL substrate transcription factor ZHX2 as an oncogenic driver in clear cell renal cell carcinoma. Science. 2018;361:290-295 pubmed publisher
  2. Du X, Wen J, Wang Y, Karmaus P, Khatamian A, Tan H, et al. Hippo/Mst signalling couples metabolic state and immune function of CD8α+ dendritic cells. Nature. 2018;558:141-145 pubmed publisher
  3. Xiao X, Fan Y, Li J, Zhang X, Lou X, Dou Y, et al. Guidance of super-enhancers in regulation of IL-9 induction and airway inflammation. J Exp Med. 2018;215:559-574 pubmed publisher
  4. Giampazolias E, Zunino B, Dhayade S, Bock F, Cloix C, Cao K, et al. Mitochondrial permeabilization engages NF-κB-dependent anti-tumour activity under caspase deficiency. Nat Cell Biol. 2017;19:1116-1129 pubmed publisher
  5. Labrousse Arias D, Martínez Alonso E, Corral Escariz M, Bienes Martínez R, Berridy J, Serrano Oviedo L, et al. VHL promotes immune response against renal cell carcinoma via NF-κB-dependent regulation of VCAM-1. J Cell Biol. 2017;216:835-847 pubmed publisher
  6. Hammers D, Sleeper M, Forbes S, Coker C, Jirousek M, Zimmer M, et al. Disease-modifying effects of orally bioavailable NF-κB inhibitors in dystrophin-deficient muscle. JCI Insight. 2016;1:e90341 pubmed publisher
  7. Lyroni K, Patsalos A, Daskalaki M, Doxaki C, Soennichsen B, Helms M, et al. Epigenetic and Transcriptional Regulation of IRAK-M Expression in Macrophages. J Immunol. 2017;198:1297-1307 pubmed publisher
  8. Sikora M, Jacobsen B, Levine K, Chen J, Davidson N, Lee A, et al. WNT4 mediates estrogen receptor signaling and endocrine resistance in invasive lobular carcinoma cell lines. Breast Cancer Res. 2016;18:92 pubmed publisher
  9. Hoare M, Ito Y, Kang T, Weekes M, Matheson N, Patten D, et al. NOTCH1 mediates a switch between two distinct secretomes during senescence. Nat Cell Biol. 2016;18:979-92 pubmed publisher
  10. Ta M, Schwensen K, Liuwantara D, Huso D, Watnick T, Rangan G. Constitutive renal Rel/nuclear factor-?B expression in Lewis polycystic kidney disease rats. World J Nephrol. 2016;5:339-57 pubmed publisher
  11. Douanne T, Gavard J, Bidère N. The paracaspase MALT1 cleaves the LUBAC subunit HOIL1 during antigen receptor signaling. J Cell Sci. 2016;129:1775-80 pubmed publisher
  12. Menter T, Dickenmann M, Juskevicius D, Steiger J, Dirnhofer S, Tzankov A. Comprehensive phenotypic characterization of PTLD reveals potential reliance on EBV or NF-κB signalling instead of B-cell receptor signalling. Hematol Oncol. 2017;35:187-197 pubmed publisher
  13. Ono R, Kaisho T, Tanaka T. PDLIM1 inhibits NF-κB-mediated inflammatory signaling by sequestering the p65 subunit of NF-κB in the cytoplasm. Sci Rep. 2015;5:18327 pubmed publisher
  14. Hunter J, Butterworth J, Zhao B, Sellier H, Campbell K, Thomas H, et al. The NF-κB subunit c-Rel regulates Bach2 tumour suppressor expression in B-cell lymphoma. Oncogene. 2016;35:3476-84 pubmed publisher
  15. Finkin S, Yuan D, Stein I, Taniguchi K, Weber A, Unger K, et al. Ectopic lymphoid structures function as microniches for tumor progenitor cells in hepatocellular carcinoma. Nat Immunol. 2015;16:1235-44 pubmed publisher
  16. Salisbury R, Sulentic C. The AhR and NF-κB/Rel Proteins Mediate the Inhibitory Effect of 2,3,7,8-Tetrachlorodibenzo-p-Dioxin on the 3' Immunoglobulin Heavy Chain Regulatory Region. Toxicol Sci. 2015;148:443-59 pubmed publisher
  17. Xiao X, Shi X, Fan Y, Zhang X, Wu M, Lan P, et al. GITR subverts Foxp3(+) Tregs to boost Th9 immunity through regulation of histone acetylation. Nat Commun. 2015;6:8266 pubmed publisher
  18. Sibbesen N, Kopp K, Litvinov I, Jønson L, Willerslev Olsen A, Fredholm S, et al. Jak3, STAT3, and STAT5 inhibit expression of miR-22, a novel tumor suppressor microRNA, in cutaneous T-Cell lymphoma. Oncotarget. 2015;6:20555-69 pubmed
  19. Iannetti A, Ledoux A, Tudhope S, Sellier H, Zhao B, Mowla S, et al. Regulation of p53 and Rb links the alternative NF-κB pathway to EZH2 expression and cell senescence. PLoS Genet. 2014;10:e1004642 pubmed publisher
  20. Dannappel M, Vlantis K, Kumari S, Polykratis A, Kim C, Wachsmuth L, et al. RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis. Nature. 2014;513:90-4 pubmed publisher
  21. Baens M, Bonsignore L, Somers R, Vanderheydt C, Weeks S, Gunnarsson J, et al. MALT1 auto-proteolysis is essential for NF-?B-dependent gene transcription in activated lymphocytes. PLoS ONE. 2014;9:e103774 pubmed publisher
  22. Ma L, Pan Q, Sun F, Yu Y, Wang J. Cluster of differentiation 166 (CD166) regulates cluster of differentiation (CD44) via NF-?B in liver cancer cell line Bel-7402. Biochem Biophys Res Commun. 2014;451:334-8 pubmed publisher
  23. Kim C, Pasparakis M. Epidermal p65/NF-?B signalling is essential for skin carcinogenesis. EMBO Mol Med. 2014;6:970-83 pubmed publisher
  24. Piao H, Yuan Y, Wang M, Sun Y, Liang H, Ma L. ?-catenin acts as a tumour suppressor in E-cadherin-negative basal-like breast cancer by inhibiting NF-?B signalling. Nat Cell Biol. 2014;16:245-54 pubmed publisher
  25. Ledoux A, Sellier H, Gillies K, Iannetti A, James J, Perkins N. NF?B regulates expression of Polo-like kinase 4. Cell Cycle. 2013;12:3052-62 pubmed publisher
  26. Newman A, Scholefield C, Kemp A, Newman M, McIver E, Kamal A, et al. TBK1 kinase addiction in lung cancer cells is mediated via autophagy of Tax1bp1/Ndp52 and non-canonical NF-?B signalling. PLoS ONE. 2012;7:e50672 pubmed publisher
  27. Wu Y, Tan H, Huang Q, Sun X, Zhu X, Shen H. zVAD-induced necroptosis in L929 cells depends on autocrine production of TNF? mediated by the PKC-MAPKs-AP-1 pathway. Cell Death Differ. 2011;18:26-37 pubmed publisher