This is a Validated Antibody Database (VAD) review about human Ran, based on 23 published articles (read how Labome selects the articles), using Ran antibody in all methods. It is aimed to help Labome visitors find the most suited Ran antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Ran synonym: ARA24; Gsp1; TC4

Santa Cruz Biotechnology
mouse monoclonal (ARAN1)
  • western blot; human; loading ...; fig ev3c
Santa Cruz Biotechnology Ran antibody (Santa, sc-58467) was used in western blot on human samples (fig ev3c). EMBO J (2019) ncbi
mouse monoclonal (ARAN1)
  • western blot; human; 1:1000; fig 3
Santa Cruz Biotechnology Ran antibody (Santa Cruz Biotechnology, sc-58467) was used in western blot on human samples at 1:1000 (fig 3). Cancer Biol Ther (2015) ncbi
mouse monoclonal (A-7)
  • immunohistochemistry - paraffin section; human; 1:500; loading ...; fig 5
  • western blot; human; loading ...; fig 3
Santa Cruz Biotechnology Ran antibody (Santa Cruz Biotechnology, sc-271376) was used in immunohistochemistry - paraffin section on human samples at 1:500 (fig 5) and in western blot on human samples (fig 3). PLoS ONE (2014) ncbi
mouse monoclonal (A-7)
  • western blot; human; fig 3a
Santa Cruz Biotechnology Ran antibody (Santa, sc-271376) was used in western blot on human samples (fig 3a). Oncotarget (2014) ncbi
mouse monoclonal (A-7)
  • western blot; human
Santa Cruz Biotechnology Ran antibody (Santa, sc-271376) was used in western blot on human samples . Mol Cancer Res (2014) ncbi
Abcam
domestic rabbit monoclonal
  • western blot; mouse; 1:500; loading ...; fig 6b
Abcam Ran antibody (Abcam, ab157213) was used in western blot on mouse samples at 1:500 (fig 6b). J Biol Chem (2019) ncbi
BD Biosciences
mouse monoclonal (20/Ran)
  • immunohistochemistry; mouse; loading ...; fig s8e
BD Biosciences Ran antibody (BD, 610340) was used in immunohistochemistry on mouse samples (fig s8e). Nat Neurosci (2021) ncbi
mouse monoclonal (20/Ran)
  • western blot; human; 1:500; loading ...; fig 4c
BD Biosciences Ran antibody (BD Bioscience, 610341) was used in western blot on human samples at 1:500 (fig 4c). elife (2020) ncbi
mouse monoclonal (20/Ran)
  • immunocytochemistry; human; 1:4000; loading ...; fig 7s1b
  • western blot; human; 1:2000; loading ...; fig 7s1a
BD Biosciences Ran antibody (BD Biosciences, 610341) was used in immunocytochemistry on human samples at 1:4000 (fig 7s1b) and in western blot on human samples at 1:2000 (fig 7s1a). elife (2019) ncbi
mouse monoclonal (20/Ran)
  • immunocytochemistry; human; 1:500; loading ...; fig 8d
BD Biosciences Ran antibody (BD Bioscience, 610340) was used in immunocytochemistry on human samples at 1:500 (fig 8d). Neuron (2019) ncbi
mouse monoclonal (20/Ran)
  • western blot; rat; fig 9a
BD Biosciences Ran antibody (BD Biosciences, 610341) was used in western blot on rat samples (fig 9a). Biochem J (2016) ncbi
mouse monoclonal (20/Ran)
  • western blot; mouse; 1:1000; loading ...; fig s1b
BD Biosciences Ran antibody (BD Transduction Laboratories, 610340) was used in western blot on mouse samples at 1:1000 (fig s1b). Nat Commun (2016) ncbi
mouse monoclonal (20/Ran)
  • western blot; mouse; fig 2
BD Biosciences Ran antibody (BD, 610341) was used in western blot on mouse samples (fig 2). Stem Cell Reports (2016) ncbi
mouse monoclonal (20/Ran)
  • western blot; human; fig 3
BD Biosciences Ran antibody (bD Bioscience, 610341) was used in western blot on human samples (fig 3). Sci Signal (2016) ncbi
mouse monoclonal (20/Ran)
  • western blot; human; fig 5
BD Biosciences Ran antibody (BD Biosciences, 610340) was used in western blot on human samples (fig 5). Mol Biol Cell (2016) ncbi
mouse monoclonal (20/Ran)
  • other; human; loading ...; fig st1
In order to use size exclusion chromatography-microsphere-based affinity proteomics to study clinical samples obtained from pediatric acute leukemia patients, BD Biosciences Ran antibody (BD, 20) was used in other on human samples (fig st1). Mol Cell Proteomics (2016) ncbi
mouse monoclonal (20/Ran)
  • western blot; Xenopus laevis; 1:2000
In order to investigate how lamins regulate the size of the nucleus, BD Biosciences Ran antibody (BD Transduction Laboratories, 610341) was used in western blot on Xenopus laevis samples at 1:2000. J Biol Chem (2015) ncbi
mouse monoclonal (20/Ran)
  • western blot; human; 1:10,000; fig 4
  • western blot; mouse; 1:1000; fig 4
BD Biosciences Ran antibody (BD Biosciences, 20/Ran) was used in western blot on human samples at 1:10,000 (fig 4) and in western blot on mouse samples at 1:1000 (fig 4). elife (2015) ncbi
mouse monoclonal (20/Ran)
  • western blot; human; 1:10,000; fig 1
BD Biosciences Ran antibody (BD biosciences, 610340) was used in western blot on human samples at 1:10,000 (fig 1). PLoS ONE (2015) ncbi
mouse monoclonal (20/Ran)
  • immunocytochemistry; human; fig 1d
  • western blot; human; fig 7a
BD Biosciences Ran antibody (BD, 610341) was used in immunocytochemistry on human samples (fig 1d) and in western blot on human samples (fig 7a). Mol Biol Cell (2014) ncbi
mouse monoclonal (20/Ran)
  • western blot; mouse
BD Biosciences Ran antibody (BD Transduction Laboratories, 610340) was used in western blot on mouse samples . Mol Cell Biol (2013) ncbi
mouse monoclonal (20/Ran)
  • western blot; mouse
BD Biosciences Ran antibody (BD, 610340) was used in western blot on mouse samples . Nucleic Acids Res (2012) ncbi
MilliporeSigma
mouse monoclonal (ARAN1)
  • western blot; human; 1:1000; loading ...; fig 1e
MilliporeSigma Ran antibody (Sigma-Aldrich, R4777) was used in western blot on human samples at 1:1000 (fig 1e). Nat Commun (2017) ncbi
Articles Reviewed
  1. Van Alstyne M, Tattoli I, Delestrée N, Recinos Y, Workman E, Shihabuddin L, et al. Gain of toxic function by long-term AAV9-mediated SMN overexpression in the sensorimotor circuit. Nat Neurosci. 2021;24:930-940 pubmed publisher
  2. Hayes L, Duan L, Bowen K, Kalab P, Rothstein J. C9orf72 arginine-rich dipeptide repeat proteins disrupt karyopherin-mediated nuclear import. elife. 2020;9: pubmed publisher
  3. Bendriem R, Singh S, Aleem A, Antonetti D, Ross M. Tight junction protein occludin regulates progenitor Self-Renewal and survival in developing cortex. elife. 2019;8: pubmed publisher
  4. Chatzifrangkeskou M, Pefani D, Eyres M, Vendrell I, Fischer R, Panková D, et al. RASSF1A is required for the maintenance of nuclear actin levels. EMBO J. 2019;38:e101168 pubmed publisher
  5. Brody M, Vanhoutte D, Bakshi C, Liu R, Correll R, Sargent M, et al. Disruption of valosin-containing protein activity causes cardiomyopathy and reveals pleiotropic functions in cardiac homeostasis. J Biol Chem. 2019;294:8918-8929 pubmed publisher
  6. Gasset Rosa F, Lu S, Yu H, Chen C, Melamed Z, Guo L, et al. Cytoplasmic TDP-43 De-mixing Independent of Stress Granules Drives Inhibition of Nuclear Import, Loss of Nuclear TDP-43, and Cell Death. Neuron. 2019;102:339-357.e7 pubmed publisher
  7. Oldrini B, Hsieh W, Erdjument Bromage H, Codega P, Carro M, Curiel García A, et al. EGFR feedback-inhibition by Ran-binding protein 6 is disrupted in cancer. Nat Commun. 2017;8:2035 pubmed publisher
  8. Bartlett J, Trivedi P, Yeung P, Kienesberger P, Pulinilkunnil T. Doxorubicin impairs cardiomyocyte viability by suppressing transcription factor EB expression and disrupting autophagy. Biochem J. 2016;473:3769-3789 pubmed
  9. Desrochers L, Bordeleau F, Reinhart King C, Cerione R, Antonyak M. Microvesicles provide a mechanism for intercellular communication by embryonic stem cells during embryo implantation. Nat Commun. 2016;7:11958 pubmed publisher
  10. Borkent M, Bennett B, Lackford B, Bar Nur O, Brumbaugh J, Wang L, et al. A Serial shRNA Screen for Roadblocks to Reprogramming Identifies the Protein Modifier SUMO2. Stem Cell Reports. 2016;6:704-716 pubmed publisher
  11. Kline C, van den Heuvel A, Allen J, Prabhu V, Dicker D, El Deiry W. ONC201 kills solid tumor cells by triggering an integrated stress response dependent on ATF4 activation by specific eIF2α kinases. Sci Signal. 2016;9:ra18 pubmed publisher
  12. Cekan P, Hasegawa K, Pan Y, Tubman E, Odde D, Chen J, et al. RCC1-dependent activation of Ran accelerates cell cycle and DNA repair, inhibiting DNA damage-induced cell senescence. Mol Biol Cell. 2016;27:1346-57 pubmed publisher
  13. Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
  14. Jevtić P, Edens L, Li X, Nguyen T, Chen P, Levy D. Concentration-dependent Effects of Nuclear Lamins on Nuclear Size in Xenopus and Mammalian Cells. J Biol Chem. 2015;290:27557-71 pubmed publisher
  15. Cohen D, Won K, Nguyen N, Lazar M, Chen C, Steger D. ATF4 licenses C/EBPβ activity in human mesenchymal stem cells primed for adipogenesis. elife. 2015;4:e06821 pubmed publisher
  16. Khuperkar D, Helen M, Magre I, Joseph J. Inter-cellular transport of ran GTPase. PLoS ONE. 2015;10:e0125506 pubmed publisher
  17. Kushwaha D, O Leary C, Cron K, Deraska P, Zhu K, D Andrea A, et al. USP9X inhibition promotes radiation-induced apoptosis in non-small cell lung cancer cells expressing mid-to-high MCL1. Cancer Biol Ther. 2015;16:392-401 pubmed publisher
  18. Manohar M, Khan H, Sirohi V, Das V, Agarwal A, Pandey A, et al. Alteration in endometrial proteins during early- and mid-secretory phases of the cycle in women with unexplained infertility. PLoS ONE. 2014;9:e111687 pubmed publisher
  19. Kazyken D, Kaz Y, Kiyan V, Zhylkibayev A, Chen C, Agarwal N, et al. The nuclear import of ribosomal proteins is regulated by mTOR. Oncotarget. 2014;5:9577-93 pubmed
  20. Wei D, Goldfarb D, Song S, Cannon C, Yan F, Sakellariou Thompson D, et al. SNF5/INI1 deficiency redefines chromatin remodeling complex composition during tumor development. Mol Cancer Res. 2014;12:1574-85 pubmed publisher
  21. Datta S, Snow C, Paschal B. A pathway linking oxidative stress and the Ran GTPase system in progeria. Mol Biol Cell. 2014;25:1202-15 pubmed publisher
  22. DiSpirito J, Fang B, Wang F, Lazar M. Pruning of the adipocyte peroxisome proliferator-activated receptor ? cistrome by hematopoietic master regulator PU.1. Mol Cell Biol. 2013;33:3354-64 pubmed publisher
  23. Freudenberg J, Ghosh S, Lackford B, Yellaboina S, Zheng X, Li R, et al. Acute depletion of Tet1-dependent 5-hydroxymethylcytosine levels impairs LIF/Stat3 signaling and results in loss of embryonic stem cell identity. Nucleic Acids Res. 2012;40:3364-77 pubmed publisher