This is a Validated Antibody Database (VAD) review about human RalA, based on 16 published articles (read how Labome selects the articles), using RalA antibody in all methods. It is aimed to help Labome visitors find the most suited RalA antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
RalA synonym: RAL

Knockout validation
Abcam
domestic rabbit monoclonal (EPR6468)
  • immunocytochemistry knockout validation; human; 1:200; loading ...; fig 1c
  • immunohistochemistry - paraffin section; human; 1:2000; loading ...; fig 5f
Abcam RalA antibody (Abcam, ab126627) was used in immunocytochemistry knockout validation on human samples at 1:200 (fig 1c) and in immunohistochemistry - paraffin section on human samples at 1:2000 (fig 5f). Breast Cancer Res (2021) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D6G8)
  • western blot knockout validation; human; loading ...; fig 1a
Cell Signaling Technology RalA antibody (Cell Signaling, 4799) was used in western blot knockout validation on human samples (fig 1a). Breast Cancer Res (2021) ncbi
BD Biosciences
mouse monoclonal (8/Ral A)
  • immunohistochemistry; fruit fly ; loading ...; fig 1a
  • immunohistochemistry knockout validation; mouse; loading ...; fig 3i
BD Biosciences RalA antibody (BD Biosciences, 610222) was used in immunohistochemistry on fruit fly samples (fig 1a) and in immunohistochemistry knockout validation on mouse samples (fig 3i). Cell Stem Cell (2019) ncbi
Abcam
domestic rabbit monoclonal (EPR6468)
  • immunocytochemistry knockout validation; human; 1:200; loading ...; fig 1c
  • immunohistochemistry - paraffin section; human; 1:2000; loading ...; fig 5f
Abcam RalA antibody (Abcam, ab126627) was used in immunocytochemistry knockout validation on human samples at 1:200 (fig 1c) and in immunohistochemistry - paraffin section on human samples at 1:2000 (fig 5f). Breast Cancer Res (2021) ncbi
domestic rabbit monoclonal (EPR6468)
  • western blot; human; loading ...; fig 3d
Abcam RalA antibody (Abcam, ab126627) was used in western blot on human samples (fig 3d). Mol Cell (2019) ncbi
domestic rabbit monoclonal (EPR6468)
  • immunocytochemistry; human; 1:200; loading ...; fig 3b
  • western blot; human; loading ...; fig 3a
Abcam RalA antibody (Abcam, ab126627) was used in immunocytochemistry on human samples at 1:200 (fig 3b) and in western blot on human samples (fig 3a). Oncotarget (2017) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D6G8)
  • western blot knockout validation; human; loading ...; fig 1a
Cell Signaling Technology RalA antibody (Cell Signaling, 4799) was used in western blot knockout validation on human samples (fig 1a). Breast Cancer Res (2021) ncbi
BD Biosciences
mouse monoclonal (8/Ral A)
  • immunocytochemistry; mouse; loading ...; fig 1c
  • western blot; mouse; loading ...; fig 1s1a
BD Biosciences RalA antibody (BD, 610221) was used in immunocytochemistry on mouse samples (fig 1c) and in western blot on mouse samples (fig 1s1a). elife (2021) ncbi
mouse monoclonal (8/Ral A)
  • western blot; mouse; 1:1000; loading ...; fig 1d
BD Biosciences RalA antibody (BD Biosciences, 610221) was used in western blot on mouse samples at 1:1000 (fig 1d). J Cell Biol (2019) ncbi
mouse monoclonal (8/Ral A)
  • immunocytochemistry; rat; 1:50; loading ...; fig 1g
BD Biosciences RalA antibody (BD, 610222) was used in immunocytochemistry on rat samples at 1:50 (fig 1g). J Cell Biol (2019) ncbi
mouse monoclonal (8/Ral A)
  • western blot; human; 1:4000; loading ...; fig s9
BD Biosciences RalA antibody (BD Transduction Laboratory, 610221) was used in western blot on human samples at 1:4000 (fig s9). J Biol Chem (2019) ncbi
mouse monoclonal (8/Ral A)
  • immunohistochemistry; fruit fly ; loading ...; fig 1a
  • immunohistochemistry knockout validation; mouse; loading ...; fig 3i
BD Biosciences RalA antibody (BD Biosciences, 610222) was used in immunohistochemistry on fruit fly samples (fig 1a) and in immunohistochemistry knockout validation on mouse samples (fig 3i). Cell Stem Cell (2019) ncbi
mouse monoclonal (8/Ral A)
  • western blot; human; loading ...; fig s3c
BD Biosciences RalA antibody (BD, 610221) was used in western blot on human samples (fig s3c). Cancer Res (2018) ncbi
mouse monoclonal (8/Ral A)
  • western blot; mouse; 1:2000; fig s1a
BD Biosciences RalA antibody (BD Transduction, 610221) was used in western blot on mouse samples at 1:2000 (fig s1a). Cell Signal (2016) ncbi
mouse monoclonal (8/Ral A)
  • western blot; human; 1:1000; fig 6
BD Biosciences RalA antibody (BD Biosciences, 610222) was used in western blot on human samples at 1:1000 (fig 6). PLoS ONE (2016) ncbi
mouse monoclonal (8/Ral A)
  • western blot; mouse; fig s1
BD Biosciences RalA antibody (BD, 610221) was used in western blot on mouse samples (fig s1). J Cell Biol (2015) ncbi
mouse monoclonal (8/Ral A)
  • western blot; human; 1:5000
BD Biosciences RalA antibody (BD Transduction Laboratories, 610221) was used in western blot on human samples at 1:5000. Int J Mol Med (2015) ncbi
mouse monoclonal (8/Ral A)
  • western blot; mouse; loading ...; fig 3c
BD Biosciences RalA antibody (BD Biosciences, 610221) was used in western blot on mouse samples (fig 3c). J Biol Chem (2015) ncbi
mouse monoclonal (8/Ral A)
  • immunohistochemistry - paraffin section; mouse
  • western blot; mouse
BD Biosciences RalA antibody (BD, 610222) was used in immunohistochemistry - paraffin section on mouse samples and in western blot on mouse samples . Curr Biol (2012) ncbi
mouse monoclonal (8/Ral A)
  • immunocytochemistry; mouse
BD Biosciences RalA antibody (BD Biosciences, 610221) was used in immunocytochemistry on mouse samples . Oncogene (2011) ncbi
Articles Reviewed
  1. Thies K, Cole M, Schafer R, Spehar J, Richardson D, Steck S, et al. The small G-protein RalA promotes progression and metastasis of triple-negative breast cancer. Breast Cancer Res. 2021;23:65 pubmed publisher
  2. Ghoroghi S, Mary B, Larnicol A, Asokan N, Klein A, Osmani N, et al. Ral GTPases promote breast cancer metastasis by controlling biogenesis and organ targeting of exosomes. elife. 2021;10: pubmed publisher
  3. Ommer A, Figlia G, Pereira J, Datwyler A, Gerber J, Degeer J, et al. Ral GTPases in Schwann cells promote radial axonal sorting in the peripheral nervous system. J Cell Biol. 2019;: pubmed publisher
  4. Galino J, Cervellini I, Zhu N, Stöberl N, Hütte M, Fricker F, et al. RalGTPases contribute to Schwann cell repair after nerve injury via regulation of process formation. J Cell Biol. 2019;: pubmed publisher
  5. Lee S, Mayr C. Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation. Mol Cell. 2019;: pubmed publisher
  6. Pergu R, Dagar S, Kumar H, Kumar R, Bhattacharya J, Mylavarapu S. The chaperone ERp29 is required for tunneling nanotube formation by stabilizing MSec. J Biol Chem. 2019;294:7177-7193 pubmed publisher
  7. Johansson J, Nászai M, Hodder M, Pickering K, Miller B, Ridgway R, et al. RAL GTPases Drive Intestinal Stem Cell Function and Regeneration through Internalization of WNT Signalosomes. Cell Stem Cell. 2019;24:592-607.e7 pubmed publisher
  8. Yu R, Longo J, van Leeuwen J, Mullen P, Ba Alawi W, Haibe Kains B, et al. Statin-Induced Cancer Cell Death Can Be Mechanistically Uncoupled from Prenylation of RAS Family Proteins. Cancer Res. 2018;78:1347-1357 pubmed publisher
  9. Omsland M, Bruserud Ã, Gjertsen B, Andresen V. Tunneling nanotube (TNT) formation is downregulated by cytarabine and NF-κB inhibition in acute myeloid leukemia (AML). Oncotarget. 2017;8:7946-7963 pubmed publisher
  10. Pawar A, Meier J, Dasgupta A, Diwanji N, Deshpande N, Saxena K, et al. Ral-Arf6 crosstalk regulates Ral dependent exocyst trafficking and anchorage independent growth signalling. Cell Signal. 2016;28:1225-36 pubmed publisher
  11. O Santos A, Parrini M, Camonis J. RalGPS2 Is Essential for Survival and Cell Cycle Progression of Lung Cancer Cells Independently of Its Established Substrates Ral GTPases. PLoS ONE. 2016;11:e0154840 pubmed publisher
  12. Hyenne V, Apaydin A, Rodriguez D, Spiegelhalter C, Hoff Yoessle S, Diem M, et al. RAL-1 controls multivesicular body biogenesis and exosome secretion. J Cell Biol. 2015;211:27-37 pubmed publisher
  13. Ishikawa T, Takizawa T, Iwaki J, Mishima T, Ui Tei K, Takeshita T, et al. Fc gamma receptor IIb participates in maternal IgG trafficking of human placental endothelial cells. Int J Mol Med. 2015;35:1273-89 pubmed publisher
  14. Buchner D, Charrier A, Srinivasan E, Wang L, Paulsen M, Ljungman M, et al. Zinc finger protein 407 (ZFP407) regulates insulin-stimulated glucose uptake and glucose transporter 4 (Glut4) mRNA. J Biol Chem. 2015;290:6376-86 pubmed publisher
  15. Peschard P, McCarthy A, Leblanc Dominguez V, Yeo M, Guichard S, Stamp G, et al. Genetic deletion of RALA and RALB small GTPases reveals redundant functions in development and tumorigenesis. Curr Biol. 2012;22:2063-8 pubmed publisher
  16. Fernández R, Ruiz Miró M, Dolcet X, Aldea M, Gari E. Cyclin D1 interacts and collaborates with Ral GTPases enhancing cell detachment and motility. Oncogene. 2011;30:1936-46 pubmed publisher