This is a Validated Antibody Database (VAD) review about human RRAGA, based on 11 published articles (read how Labome selects the articles), using RRAGA antibody in all methods. It is aimed to help Labome visitors find the most suited RRAGA antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
RRAGA synonym: FIP-1; FIP1; RAGA; ras-related GTP-binding protein A; adenovirus E3 14.7 kDa-interacting protein 1; adenovirus E3-14.7K interacting protein 1; rag A

Knockout validation
Cell Signaling Technology
rabbit monoclonal (D8B5)
  • western blot knockout validation; human; loading ...; fig 1d
Cell Signaling Technology RRAGA antibody (Cell Signaling, 4357) was used in western blot knockout validation on human samples (fig 1d). Nature (2017) ncbi
Cell Signaling Technology
rabbit monoclonal (D8B5)
  • western blot knockout validation; mouse; 1:1000; fig s1a
  • immunocytochemistry knockout validation; human; 1:100; fig s10c
  • western blot; human; fig s9e
Cell Signaling Technology RRAGA antibody (Cell signaling, 4357) was used in western blot knockout validation on mouse samples at 1:1000 (fig s1a), in immunocytochemistry knockout validation on human samples at 1:100 (fig s10c) and in western blot on human samples (fig s9e). Science (2015) ncbi
Cell Signaling Technology
rabbit monoclonal (D8B5)
  • western blot; human; 1:1000; loading ...; fig 4a
Cell Signaling Technology RRAGA antibody (Cell Signaling, 4357) was used in western blot on human samples at 1:1000 (fig 4a). Nat Commun (2018) ncbi
rabbit monoclonal (D8B5)
  • western blot knockout validation; human; loading ...; fig 1d
Cell Signaling Technology RRAGA antibody (Cell Signaling, 4357) was used in western blot knockout validation on human samples (fig 1d). Nature (2017) ncbi
rabbit monoclonal (D8B5)
  • western blot; human; fig 6a
Cell Signaling Technology RRAGA antibody (Cell Signaling, 4357) was used in western blot on human samples (fig 6a). Cell (2016) ncbi
rabbit monoclonal (D8B5)
  • western blot; human; 1:1000; fig s2
In order to elucidate the mechanisms by which mutant IDH1/2 contributes to oncogenesis, Cell Signaling Technology RRAGA antibody (Cell signaling, D8B5) was used in western blot on human samples at 1:1000 (fig s2). Nat Commun (2016) ncbi
rabbit monoclonal (D8B5)
  • western blot; human; fig 3
Cell Signaling Technology RRAGA antibody (Cell Signaling, 4357) was used in western blot on human samples (fig 3). PLoS Genet (2016) ncbi
rabbit monoclonal (D8B5)
  • western blot; rat; fig 3
Cell Signaling Technology RRAGA antibody (Cell Signaling Technology, 4357) was used in western blot on rat samples (fig 3). J Nutr (2015) ncbi
rabbit monoclonal (D8B5)
  • western blot knockout validation; mouse; 1:1000; fig s1a
  • immunocytochemistry knockout validation; human; 1:100; fig s10c
  • western blot; human; fig s9e
Cell Signaling Technology RRAGA antibody (Cell signaling, 4357) was used in western blot knockout validation on mouse samples at 1:1000 (fig s1a), in immunocytochemistry knockout validation on human samples at 1:100 (fig s10c) and in western blot on human samples (fig s9e). Science (2015) ncbi
rabbit monoclonal (D8B5)
  • immunoprecipitation; human; fig 1
  • western blot; human; fig 1
Cell Signaling Technology RRAGA antibody (Cell signaling, 4357) was used in immunoprecipitation on human samples (fig 1) and in western blot on human samples (fig 1). Nature (2015) ncbi
rabbit monoclonal (D8B5)
  • immunoprecipitation; human; fig 5
  • western blot; human; fig s6
Cell Signaling Technology RRAGA antibody (Cell Signaling, 4357) was used in immunoprecipitation on human samples (fig 5) and in western blot on human samples (fig s6). Cell (2014) ncbi
rabbit monoclonal (D8B5)
  • western blot; human
Cell Signaling Technology RRAGA antibody (Cell Signaling Technology, 4357) was used in western blot on human samples . J Biol Chem (2014) ncbi
rabbit monoclonal (D8B5)
  • western blot; human; 1:500
Cell Signaling Technology RRAGA antibody (Cell Signaling Technology, 4357) was used in western blot on human samples at 1:500. J Virol (2013) ncbi
Articles Reviewed
  1. Hsu C, Lee E, Gordon K, Paz E, Shen W, Ohnishi K, et al. MAP4K3 mediates amino acid-dependent regulation of autophagy via phosphorylation of TFEB. Nat Commun. 2018;9:942 pubmed publisher
  2. Peng M, Yin N, Li M. SZT2 dictates GATOR control of mTORC1 signalling. Nature. 2017;543:433-437 pubmed publisher
  3. Wu L, Zhou B, Oshiro Rapley N, Li M, Paulo J, Webster C, et al. An Ancient, Unified Mechanism for Metformin Growth Inhibition in C. elegans and Cancer. Cell. 2016;167:1705-1718.e13 pubmed publisher
  4. Carbonneau M, M Gagné L, Lalonde M, Germain M, Motorina A, Guiot M, et al. The oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathway. Nat Commun. 2016;7:12700 pubmed publisher
  5. Chen J, Huang C, Zhang B, Yin S, Liang J, Xu C, et al. Mutations of RagA GTPase in mTORC1 Pathway Are Associated with Autosomal Dominant Cataracts. PLoS Genet. 2016;12:e1006090 pubmed publisher
  6. Kimball S, Ravi S, Gordon B, Dennis M, Jefferson L. Amino Acid-Induced Activation of mTORC1 in Rat Liver Is Attenuated by Short-Term Consumption of a High-Fat Diet. J Nutr. 2015;145:2496-502 pubmed publisher
  7. Jewell J, Kim Y, Russell R, Yu F, Park H, Plouffe S, et al. Metabolism. Differential regulation of mTORC1 by leucine and glutamine. Science. 2015;347:194-8 pubmed publisher
  8. Rebsamen M, Pochini L, Stasyk T, de Araújo M, Galluccio M, Kandasamy R, et al. SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1. Nature. 2015;519:477-81 pubmed publisher
  9. Peng M, Yin N, Li M. Sestrins function as guanine nucleotide dissociation inhibitors for Rag GTPases to control mTORC1 signaling. Cell. 2014;159:122-133 pubmed publisher
  10. Oshiro N, Rapley J, Avruch J. Amino acids activate mammalian target of rapamycin (mTOR) complex 1 without changing Rag GTPase guanyl nucleotide charging. J Biol Chem. 2014;289:2658-74 pubmed publisher
  11. McNulty S, Flint M, Nichol S, Spiropoulou C. Host mTORC1 signaling regulates andes virus replication. J Virol. 2013;87:912-22 pubmed publisher