This is a Validated Antibody Database (VAD) review about human RIP, based on 51 published articles (read how Labome selects the articles), using RIP antibody in all methods. It is aimed to help Labome visitors find the most suited RIP antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
RIP synonym: IMD57; RIP; RIP-1; RIP1

Knockout validation
Novus Biologicals
domestic rabbit polyclonal
  • immunohistochemistry knockout validation; mouse; 1:100; loading ...; fig s1c, s1d
Novus Biologicals RIP antibody (Novusbio, NBP1-77077SS) was used in immunohistochemistry knockout validation on mouse samples at 1:100 (fig s1c, s1d). Acta Neuropathol Commun (2021) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D94C12)
  • western blot knockout validation; human; 1:1000; fig 3f
Cell Signaling Technology RIP antibody (Cell Signaling, 3493) was used in western blot knockout validation on human samples at 1:1000 (fig 3f). Science (2018) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D94C12)
  • western blot knockout validation; mouse; loading ...; fig 3c
Cell Signaling Technology RIP antibody (Cell Signaling, 3493) was used in western blot knockout validation on mouse samples (fig 3c). Proc Natl Acad Sci U S A (2017) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D94C12)
  • immunohistochemistry knockout validation; mouse; loading ...; fig 1b
  • western blot knockout validation; mouse; loading ...; fig 1a
Cell Signaling Technology RIP antibody (Cell Signaling, 3493) was used in immunohistochemistry knockout validation on mouse samples (fig 1b) and in western blot knockout validation on mouse samples (fig 1a). Cell Death Dis (2016) ncbi
Santa Cruz Biotechnology
mouse monoclonal (C-12)
  • immunoprecipitation; human; loading ...; fig 5i
Santa Cruz Biotechnology RIP antibody (Santa Cruz, sc-133102) was used in immunoprecipitation on human samples (fig 5i). Front Cell Dev Biol (2021) ncbi
mouse monoclonal (C-12)
  • western blot; mouse; fig 5
Santa Cruz Biotechnology RIP antibody (Santa Cruz, sc-133102) was used in western blot on mouse samples (fig 5). Cell Rep (2016) ncbi
Novus Biologicals
domestic rabbit polyclonal
  • immunohistochemistry knockout validation; mouse; 1:100; loading ...; fig s1c, s1d
Novus Biologicals RIP antibody (Novusbio, NBP1-77077SS) was used in immunohistochemistry knockout validation on mouse samples at 1:100 (fig s1c, s1d). Acta Neuropathol Commun (2021) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; human; loading ...; fig s6b
  • immunohistochemistry; human; loading ...; fig 1c
  • western blot; human; 1:1000; loading ...; fig 1d
Novus Biologicals RIP antibody (Novus Biologicals, NBP1-77077) was used in immunocytochemistry on human samples (fig s6b), in immunohistochemistry on human samples (fig 1c) and in western blot on human samples at 1:1000 (fig 1d). Cell Death Dis (2016) ncbi
Invitrogen
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 4b
Invitrogen RIP antibody (Thermo Fisher, PA5-20811) was used in western blot on mouse samples (fig 4b). Front Med (Lausanne) (2021) ncbi
Abcam
domestic rabbit monoclonal (EPR4689)
  • western blot; human; 1:1000; fig 4
Abcam RIP antibody (abcam, ab125072) was used in western blot on human samples at 1:1000 (fig 4). Oncotarget (2016) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D8I3A)
  • western blot; rat; loading ...; fig 5c
Cell Signaling Technology RIP antibody (CST, 44590) was used in western blot on rat samples (fig 5c). Int J Mol Sci (2022) ncbi
domestic rabbit monoclonal (D94C12)
  • western blot; mouse; fig 6b
Cell Signaling Technology RIP antibody (Cell Signaling, 3493) was used in western blot on mouse samples (fig 6b). J Clin Invest (2022) ncbi
domestic rabbit monoclonal (D8I3A)
  • western blot; human; 1:1000; loading ...; fig s2c
Cell Signaling Technology RIP antibody (Cell Signaling, 44590) was used in western blot on human samples at 1:1000 (fig s2c). Commun Biol (2022) ncbi
domestic rabbit monoclonal (D94C12)
  • western blot; human; loading ...; fig 2e
Cell Signaling Technology RIP antibody (Cell Signaling Technology, 3493) was used in western blot on human samples (fig 2e). Sci Adv (2021) ncbi
domestic rabbit monoclonal (D94C12)
  • western blot; human; loading ...; fig 5c
Cell Signaling Technology RIP antibody (Cell Signaling, 3493) was used in western blot on human samples (fig 5c). BMC Biol (2021) ncbi
domestic rabbit monoclonal (D94C12)
  • western blot; mouse; loading ...
Cell Signaling Technology RIP antibody (CST, 3493) was used in western blot on mouse samples . Nat Commun (2020) ncbi
domestic rabbit monoclonal (D94C12)
  • western blot; mouse; loading ...; fig 3c
Cell Signaling Technology RIP antibody (Cell Signaling Technology, 3493) was used in western blot on mouse samples (fig 3c). Cell (2021) ncbi
domestic rabbit monoclonal (D94C12)
  • immunohistochemistry; mouse; loading ...; fig s3-1
  • western blot; mouse; 1:1000; loading ...; fig 1c
Cell Signaling Technology RIP antibody (Cell Signaling, 3493S) was used in immunohistochemistry on mouse samples (fig s3-1) and in western blot on mouse samples at 1:1000 (fig 1c). elife (2020) ncbi
domestic rabbit monoclonal (D94C12)
  • immunocytochemistry; human; loading ...; fig 4a, 4b
  • western blot; human; loading ...; fig 5a, 5c
Cell Signaling Technology RIP antibody (CST, D94C12) was used in immunocytochemistry on human samples (fig 4a, 4b) and in western blot on human samples (fig 5a, 5c). Front Cell Dev Biol (2020) ncbi
domestic rabbit monoclonal (D94C12)
  • western blot; mouse; loading ...; fig 2b
Cell Signaling Technology RIP antibody (Cell Signaling technology, 3493) was used in western blot on mouse samples (fig 2b). Cell Res (2020) ncbi
domestic rabbit monoclonal (D94C12)
  • western blot; human; 1:1000; loading ...; fig 1a
Cell Signaling Technology RIP antibody (CST, 3493) was used in western blot on human samples at 1:1000 (fig 1a). Antioxidants (Basel) (2020) ncbi
domestic rabbit monoclonal (D94C12)
  • immunohistochemistry - paraffin section; human; 1:50; loading ...; fig 1a
  • western blot; human; 1:1000; loading ...; fig 2i
  • immunohistochemistry - paraffin section; mouse; 1:50; loading ...; fig 3e
  • western blot; mouse; 1:1000; loading ...; fig 3f
Cell Signaling Technology RIP antibody (Cell Signaling, 3493S) was used in immunohistochemistry - paraffin section on human samples at 1:50 (fig 1a), in western blot on human samples at 1:1000 (fig 2i), in immunohistochemistry - paraffin section on mouse samples at 1:50 (fig 3e) and in western blot on mouse samples at 1:1000 (fig 3f). Cell Death Dis (2020) ncbi
domestic rabbit monoclonal (D94C12)
  • western blot; mouse; 1:1000; loading ...; fig 2a, 3d
Cell Signaling Technology RIP antibody (CST, 3493) was used in western blot on mouse samples at 1:1000 (fig 2a, 3d). Stem Cells Dev (2020) ncbi
domestic rabbit monoclonal (D8I3A)
  • immunohistochemistry; mouse; 1:400; loading ...; fig s12c
  • western blot; mouse; 1:1000; loading ...; fig s12b
Cell Signaling Technology RIP antibody (Cell Signaling, 44590) was used in immunohistochemistry on mouse samples at 1:400 (fig s12c) and in western blot on mouse samples at 1:1000 (fig s12b). Nat Commun (2020) ncbi
domestic rabbit monoclonal (D94C12)
  • western blot; human; loading ...; fig e5b
  • western blot; mouse; loading ...; fig e4d, e4g
Cell Signaling Technology RIP antibody (Cell Signaling, 3493) was used in western blot on human samples (fig e5b) and in western blot on mouse samples (fig e4d, e4g). Nature (2020) ncbi
domestic rabbit monoclonal (D94C12)
  • western blot; human; 1:1000; loading ...; fig s1e
Cell Signaling Technology RIP antibody (Cell Signaling, D94C12) was used in western blot on human samples at 1:1000 (fig s1e). Nat Immunol (2020) ncbi
domestic rabbit monoclonal (D94C12)
  • western blot; rat; loading ...; fig 7a
Cell Signaling Technology RIP antibody (Cell Signaling Technology, 3493) was used in western blot on rat samples (fig 7a). Biomed Pharmacother (2019) ncbi
domestic rabbit monoclonal (D94C12)
  • western blot; mouse; loading ...; fig 3d
Cell Signaling Technology RIP antibody (Cell Signaling Technology, 3493) was used in western blot on mouse samples (fig 3d). Cell (2019) ncbi
domestic rabbit monoclonal (D94C12)
  • western blot; mouse; 1:3000; loading ...; fig 5b
Cell Signaling Technology RIP antibody (Cell Signaling Technology, 3493) was used in western blot on mouse samples at 1:3000 (fig 5b). J Cell Sci (2019) ncbi
domestic rabbit monoclonal (D94C12)
  • western blot; mouse; loading ...; fig 3b
Cell Signaling Technology RIP antibody (Cell Signaling, 3493) was used in western blot on mouse samples (fig 3b). J Mol Cell Cardiol (2018) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig e4
Cell Signaling Technology RIP antibody (Cell Signaling Technology, 4926) was used in western blot on human samples (fig e4). Nature (2018) ncbi
domestic rabbit monoclonal (D94C12)
  • western blot knockout validation; human; 1:1000; fig 3f
Cell Signaling Technology RIP antibody (Cell Signaling, 3493) was used in western blot knockout validation on human samples at 1:1000 (fig 3f). Science (2018) ncbi
domestic rabbit polyclonal
  • other; human; loading ...; fig 4c
Cell Signaling Technology RIP antibody (Cell Signaling, 4926) was used in other on human samples (fig 4c). Cancer Cell (2018) ncbi
domestic rabbit monoclonal (D94C12)
  • western blot; mouse; loading ...; fig 2c
  • western blot; human; loading ...; fig 4a
Cell Signaling Technology RIP antibody (Cell Signaling, 3493) was used in western blot on mouse samples (fig 2c) and in western blot on human samples (fig 4a). Proc Natl Acad Sci U S A (2018) ncbi
domestic rabbit monoclonal (D94C12)
  • western blot knockout validation; mouse; loading ...; fig 3c
Cell Signaling Technology RIP antibody (Cell Signaling, 3493) was used in western blot knockout validation on mouse samples (fig 3c). Proc Natl Acad Sci U S A (2017) ncbi
domestic rabbit monoclonal (D94C12)
  • immunoprecipitation; human; fig 5c
  • western blot; human; fig 5c
Cell Signaling Technology RIP antibody (Cell Signaling Technology, 3493) was used in immunoprecipitation on human samples (fig 5c) and in western blot on human samples (fig 5c). J Biol Chem (2017) ncbi
domestic rabbit monoclonal (D94C12)
  • western blot; human; 1:1000; loading ...; fig 5c
Cell Signaling Technology RIP antibody (Cell Signaling Technologies, 3493) was used in western blot on human samples at 1:1000 (fig 5c). J Biol Chem (2017) ncbi
domestic rabbit monoclonal (D94C12)
  • western blot; human; loading ...; fig 6a
Cell Signaling Technology RIP antibody (Cell Signaling, 3493) was used in western blot on human samples (fig 6a). J Virol (2017) ncbi
domestic rabbit monoclonal (D94C12)
  • immunoprecipitation; rat; loading ...; fig 4c
  • western blot; rat; loading ...; fig 4c
  • immunoprecipitation; human; loading ...; fig 4b
  • western blot; human; loading ...; fig 4b
Cell Signaling Technology RIP antibody (Cell Signaling, 3493) was used in immunoprecipitation on rat samples (fig 4c), in western blot on rat samples (fig 4c), in immunoprecipitation on human samples (fig 4b) and in western blot on human samples (fig 4b). Biochim Biophys Acta Mol Cell Res (2017) ncbi
domestic rabbit monoclonal (D94C12)
  • western blot; human; loading ...; fig 2a
In order to elucidate how high-risk human papillomavirus alters signaling pathways involved in cell death and growth regulation, Cell Signaling Technology RIP antibody (Cell signaling, 3493) was used in western blot on human samples (fig 2a). Front Immunol (2016) ncbi
domestic rabbit monoclonal (D94C12)
  • immunohistochemistry knockout validation; mouse; loading ...; fig 1b
  • western blot knockout validation; mouse; loading ...; fig 1a
Cell Signaling Technology RIP antibody (Cell Signaling, 3493) was used in immunohistochemistry knockout validation on mouse samples (fig 1b) and in western blot knockout validation on mouse samples (fig 1a). Cell Death Dis (2016) ncbi
domestic rabbit monoclonal (D94C12)
  • western blot; mouse; fig 1
In order to elucidate the mechanism by which RIPK1 counteracts RIPK3-MLKL-mediated necroptosis, Cell Signaling Technology RIP antibody (Cell signaling, 3493) was used in western blot on mouse samples (fig 1). Nature (2016) ncbi
domestic rabbit monoclonal (D94C12)
  • western blot; mouse; loading ...; fig 6g
Cell Signaling Technology RIP antibody (Cell Signaling, 3493) was used in western blot on mouse samples (fig 6g). J Clin Invest (2016) ncbi
domestic rabbit monoclonal (D94C12)
  • western blot; human; loading ...; fig 3f
Cell Signaling Technology RIP antibody (Cell Signaling, 3493) was used in western blot on human samples (fig 3f). Mol Cell Biol (2017) ncbi
domestic rabbit monoclonal (D94C12)
  • western blot; human
Cell Signaling Technology RIP antibody (Cell Signaling, 3493) was used in western blot on human samples . Proc Natl Acad Sci U S A (2016) ncbi
domestic rabbit monoclonal (D94C12)
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 1a
In order to develop an ex vivo paired cancerous and noncancerous human lung tissue strategy to study cancer and stromal cell metabolism in the native human tumor microenvironment, Cell Signaling Technology RIP antibody (Cell signaling, D94C12) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 1a). Cold Spring Harb Mol Case Stud (2016) ncbi
domestic rabbit monoclonal (D94C12)
  • western blot; human; 1:1000; fig 3
Cell Signaling Technology RIP antibody (Cell signaling, 3493) was used in western blot on human samples at 1:1000 (fig 3). Drug Des Devel Ther (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 5
In order to investigate the consequences of genetic or pharmacological inhibition of BMI1, Cell Signaling Technology RIP antibody (Cell Signaling Technology, 4926) was used in western blot on human samples (fig 5). Autophagy (2016) ncbi
domestic rabbit monoclonal (D94C12)
  • immunohistochemistry - paraffin section; human; loading ...; fig 1a
  • western blot; human; loading ...; fig 1c
In order to report how the parallel networks of necroptosis-induced CXCL1 and Mincle signaling promote pancreatic ductal adenocarcinoma progression, Cell Signaling Technology RIP antibody (Cell Signaling, D94C12) was used in immunohistochemistry - paraffin section on human samples (fig 1a) and in western blot on human samples (fig 1c). Nature (2016) ncbi
domestic rabbit monoclonal (D94C12)
  • immunoprecipitation; human; fig 5d
  • western blot; human; 1:1000; fig 5d
In order to show how FADD regulates NF-kappaB activation and promotes ubiquitination of cFLIPL, which induces apoptosis, Cell Signaling Technology RIP antibody (Cell signaling technology, 3493) was used in immunoprecipitation on human samples (fig 5d) and in western blot on human samples at 1:1000 (fig 5d). Sci Rep (2016) ncbi
domestic rabbit monoclonal (D94C12)
  • western blot; human; 1:1000; fig 7
In order to investigate impairment of autophagy flux and induction of cell death independent of necroptosis and apoptosis by dual PI-3 kinase/mTOR inhibition, Cell Signaling Technology RIP antibody (Cell Signaling, 3493) was used in western blot on human samples at 1:1000 (fig 7). Oncotarget (2016) ncbi
domestic rabbit monoclonal (D94C12)
  • western blot; mouse; fig 1
  • western blot; human; fig 10
Cell Signaling Technology RIP antibody (Cell Signaling, 3493) was used in western blot on mouse samples (fig 1) and in western blot on human samples (fig 10). Oncotarget (2016) ncbi
domestic rabbit monoclonal (D94C12)
  • western blot; human; 1:1000; fig 5
Cell Signaling Technology RIP antibody (Cell Signaling, 3493) was used in western blot on human samples at 1:1000 (fig 5). J Biol Chem (2016) ncbi
domestic rabbit monoclonal (D94C12)
  • western blot; mouse; loading ...; fig 5k
Cell Signaling Technology RIP antibody (Cell Signaling, 3493) was used in western blot on mouse samples (fig 5k). Sci Rep (2016) ncbi
domestic rabbit monoclonal (D94C12)
  • western blot; mouse; fig 1b
Cell Signaling Technology RIP antibody (Cell Signaling, 3493) was used in western blot on mouse samples (fig 1b). Cell Death Dis (2015) ncbi
Articles Reviewed
  1. Wen S, Unuma K, Funakoshi T, Aki T, Uemura K. Contraction Band Necrosis with Dephosphorylated Connexin 43 in Rat Myocardium after Daily Cocaine Administration. Int J Mol Sci. 2022;23: pubmed publisher
  2. Rusu I, Mennillo E, Bain J, Li Z, Sun X, Ly K, et al. Microbial signals, MyD88, and lymphotoxin drive TNF-independent intestinal epithelial tissue damage. J Clin Invest. 2022;132: pubmed publisher
  3. Wang S, Luke C, Pak S, Shi V, Chen L, Moore J, et al. SERPINB3 (SCCA1) inhibits cathepsin L and lysoptosis, protecting cervical cancer cells from chemoradiation. Commun Biol. 2022;5:46 pubmed publisher
  4. Lv Z, Xiong L, Qin X, Zhang H, Luo X, Peng W, et al. Role of GRK2 in Trophoblast Necroptosis and Spiral Artery Remodeling: Implications for Preeclampsia Pathogenesis. Front Cell Dev Biol. 2021;9:694261 pubmed publisher
  5. Gao C, Deng J, Zhang H, Li X, Gu S, Zheng M, et al. HSPA13 facilitates NF-κB-mediated transcription and attenuates cell death responses in TNFα signaling. Sci Adv. 2021;7:eabh1756 pubmed publisher
  6. Wehn A, Khalin I, Duering M, Hellal F, Culmsee C, Vandenabeele P, et al. RIPK1 or RIPK3 deletion prevents progressive neuronal cell death and improves memory function after traumatic brain injury. Acta Neuropathol Commun. 2021;9:138 pubmed publisher
  7. Zhu Y, Xie J, Shi J. Rac1/ROCK-driven membrane dynamics promote natural killer cell cytotoxicity via granzyme-induced necroptosis. BMC Biol. 2021;19:140 pubmed publisher
  8. Ngamsri K, Gamper Tsigaras J, Reutershan J, Konrad F. Fractalkine Is Linked to the Necrosome Pathway in Acute Pulmonary Inflammation. Front Med (Lausanne). 2021;8:591790 pubmed publisher
  9. Li X, Zhang M, Huang X, Liang W, Li G, Lu X, et al. Ubiquitination of RIPK1 regulates its activation mediated by TNFR1 and TLRs signaling in distinct manners. Nat Commun. 2020;11:6364 pubmed publisher
  10. Karki R, Sharma B, Tuladhar S, Williams E, Zalduondo L, Samir P, et al. Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes. Cell. 2021;184:149-168.e17 pubmed publisher
  11. Li D, Ai Y, Guo J, Dong B, Li L, Cai G, et al. Casein kinase 1G2 suppresses necroptosis-promoted testis aging by inhibiting receptor-interacting kinase 3. elife. 2020;9: pubmed publisher
  12. Hu H, Wu G, Shu Z, Yu D, Nan N, Yuan F, et al. ICP6 Prevents RIP1 Activation to Hinder Necroptosis Signaling. Front Cell Dev Biol. 2020;8:595253 pubmed publisher
  13. Zhou S, Zhang W, Cai G, Ding Y, Wei C, Li S, et al. Myofiber necroptosis promotes muscle stem cell proliferation via releasing Tenascin-C during regeneration. Cell Res. 2020;30:1063-1077 pubmed publisher
  14. Alegre Cortés E, Muriel González A, Canales Cortés S, Uribe Carretero E, Martínez Chacón G, Aiastui A, et al. Toxicity of Necrostatin-1 in Parkinson's Disease Models. Antioxidants (Basel). 2020;9: pubmed publisher
  15. Duan X, Liu X, Liu N, Huang Y, Jin Z, Zhang S, et al. Inhibition of keratinocyte necroptosis mediated by RIPK1/RIPK3/MLKL provides a protective effect against psoriatic inflammation. Cell Death Dis. 2020;11:134 pubmed publisher
  16. Xie Y, Chen H, Luo D, Yang X, Yao J, Zhang C, et al. Inhibiting Necroptosis of Spermatogonial Stem Cell as a Novel Strategy for Male Fertility Preservation. Stem Cells Dev. 2020;29:475-487 pubmed publisher
  17. Tanaka H, Homma H, Fujita K, Kondo K, Yamada S, Jin X, et al. YAP-dependent necrosis occurs in early stages of Alzheimer's disease and regulates mouse model pathology. Nat Commun. 2020;11:507 pubmed publisher
  18. Lalaoui N, Boyden S, Oda H, Wood G, Stone D, Chau D, et al. Mutations that prevent caspase cleavage of RIPK1 cause autoinflammatory disease. Nature. 2020;577:103-108 pubmed publisher
  19. Zewinger S, Reiser J, Jankowski V, Alansary D, Hahm E, Triem S, et al. Apolipoprotein C3 induces inflammation and organ damage by alternative inflammasome activation. Nat Immunol. 2020;21:30-41 pubmed publisher
  20. Qin W, Wu X, Jia Y, Tong X, Guo C, Chen D, et al. Suhuang antitussive capsule inhibits NLRP3 inflammasome activation and ameliorates pulmonary dysfunction via suppression of endoplasmic reticulum stress in cough variant asthma. Biomed Pharmacother. 2019;118:109188 pubmed publisher
  21. Vredevoogd D, Kuilman T, Ligtenberg M, Boshuizen J, Stecker K, de Bruijn B, et al. Augmenting Immunotherapy Impact by Lowering Tumor TNF Cytotoxicity Threshold. Cell. 2019;178:585-599.e15 pubmed publisher
  22. Wang Z, Feng J, Yu J, Chen G. FKBP12 mediates necroptosis by initiating RIPK1-RIPK3-MLKL signal transduction in response to TNF receptor 1 ligation. J Cell Sci. 2019;132: pubmed publisher
  23. Yang Z, Li C, Wang Y, Yang J, Yin Y, Liu M, et al. Melatonin attenuates chronic pain related myocardial ischemic susceptibility through inhibiting RIP3-MLKL/CaMKII dependent necroptosis. J Mol Cell Cardiol. 2018;125:185-194 pubmed publisher
  24. Lee S, Singh I, Tisdale S, Abdel Wahab O, Leslie C, Mayr C. Widespread intronic polyadenylation inactivates tumour suppressor genes in leukaemia. Nature. 2018;561:127-131 pubmed publisher
  25. Cuchet Lourenço D, Eletto D, Wu C, Plagnol V, Papapietro O, CURTIS J, et al. Biallelic RIPK1 mutations in humans cause severe immunodeficiency, arthritis, and intestinal inflammation. Science. 2018;361:810-813 pubmed publisher
  26. Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  27. Meng H, Liu Z, Li X, Wang H, Jin T, Wu G, et al. Death-domain dimerization-mediated activation of RIPK1 controls necroptosis and RIPK1-dependent apoptosis. Proc Natl Acad Sci U S A. 2018;115:E2001-E2009 pubmed publisher
  28. Wang H, Meng H, Li X, Zhu K, Dong K, Mookhtiar A, et al. PELI1 functions as a dual modulator of necroptosis and apoptosis by regulating ubiquitination of RIPK1 and mRNA levels of c-FLIP. Proc Natl Acad Sci U S A. 2017;114:11944-11949 pubmed publisher
  29. Wu G, Mu T, Gao Z, Wang J, Sy M, Li C. Prion protein is required for tumor necrosis factor α (TNFα)-triggered nuclear factor κB (NF-κB) signaling and cytokine production. J Biol Chem. 2017;292:18747-18759 pubmed publisher
  30. Button R, Roberts S, Willis T, Hanemann C, Luo S. Accumulation of autophagosomes confers cytotoxicity. J Biol Chem. 2017;292:13599-13614 pubmed publisher
  31. Franz S, Rennert P, Woznik M, Grützke J, Lüdde A, Arriero Pais E, et al. Mumps Virus SH Protein Inhibits NF-κB Activation by Interacting with Tumor Necrosis Factor Receptor 1, Interleukin-1 Receptor 1, and Toll-Like Receptor 3 Complexes. J Virol. 2017;91: pubmed publisher
  32. Fettweis G, Di Valentin E, L homme L, Lassence C, Dequiedt F, Fillet M, et al. RIP3 antagonizes a TSC2-mediated pro-survival pathway in glioblastoma cell death. Biochim Biophys Acta Mol Cell Res. 2017;1864:113-124 pubmed publisher
  33. Ma W, Tummers B, van Esch E, Goedemans R, Melief C, Meyers C, et al. Human Papillomavirus Downregulates the Expression of IFITM1 and RIPK3 to Escape from IFN?- and TNF?-Mediated Antiproliferative Effects and Necroptosis. Front Immunol. 2016;7:496 pubmed
  34. Filliol A, Piquet Pellorce C, Le Seyec J, Farooq M, Genet V, Lucas Clerc C, et al. RIPK1 protects from TNF-α-mediated liver damage during hepatitis. Cell Death Dis. 2016;7:e2462 pubmed publisher
  35. Lin J, Kumari S, Kim C, Van T, Wachsmuth L, Polykratis A, et al. RIPK1 counteracts ZBP1-mediated necroptosis to inhibit inflammation. Nature. 2016;540:124-128 pubmed publisher
  36. Günther C, He G, Kremer A, Murphy J, Petrie E, Amann K, et al. The pseudokinase MLKL mediates programmed hepatocellular necrosis independently of RIPK3 during hepatitis. J Clin Invest. 2016;126:4346-4360 pubmed publisher
  37. Choi Y, Shembade N, Parvatiyar K, Balachandran S, Harhaj E. TAX1BP1 Restrains Virus-Induced Apoptosis by Facilitating Itch-Mediated Degradation of the Mitochondrial Adaptor MAVS. Mol Cell Biol. 2017;37: pubmed publisher
  38. Zhou Q, Yu X, Demirkaya E, Deuitch N, Stone D, Tsai W, et al. Biallelic hypomorphic mutations in a linear deubiquitinase define otulipenia, an early-onset autoinflammatory disease. Proc Natl Acad Sci U S A. 2016;113:10127-32 pubmed publisher
  39. Fan T, Warmoes M, Sun Q, Song H, Turchan Cholewo J, Martin J, et al. Distinctly perturbed metabolic networks underlie differential tumor tissue damages induced by immune modulator ?-glucan in a two-case ex vivo non-small-cell lung cancer study. Cold Spring Harb Mol Case Stud. 2016;2:a000893 pubmed publisher
  40. Al Lamki R, Lu W, Manalo P, Wang J, Warren A, Tolkovsky A, et al. Tubular epithelial cells in renal clear cell carcinoma express high RIPK1/3 and show increased susceptibility to TNF receptor 1-induced necroptosis. Cell Death Dis. 2016;7:e2287 pubmed publisher
  41. Davis M, Delaney J, Patel C, Storgard R, Stupack D. Nelfinavir is effective against human cervical cancer cells in vivo: a potential treatment modality in resource-limited settings. Drug Des Devel Ther. 2016;10:1837-46 pubmed publisher
  42. Tortola L, Nitsch R, Bertrand M, Kogler M, Redouane Y, Kozieradzki I, et al. The Tumor Suppressor Hace1 Is a Critical Regulator of TNFR1-Mediated Cell Fate. Cell Rep. 2016;15:1481-1492 pubmed publisher
  43. Dey A, Mustafi S, Saha S, Kumar Dhar Dwivedi S, Mukherjee P, Bhattacharya R. Inhibition of BMI1 induces autophagy-mediated necroptosis. Autophagy. 2016;12:659-70 pubmed publisher
  44. Seifert L, Werba G, Tiwari S, Giao Ly N, Alothman S, Alqunaibit D, et al. The necrosome promotes pancreatic oncogenesis via CXCL1 and Mincle-induced immune suppression. Nature. 2016;532:245-9 pubmed publisher
  45. Ranjan K, Pathak C. FADD regulates NF-κB activation and promotes ubiquitination of cFLIPL to induce apoptosis. Sci Rep. 2016;6:22787 pubmed publisher
  46. Wang X, Ma C, Zong Z, Xiao Y, Li N, Guo C, et al. A20 inhibits the motility of HCC cells induced by TNF-α. Oncotarget. 2016;7:14742-54 pubmed publisher
  47. Button R, Vincent J, Strang C, Luo S. Dual PI-3 kinase/mTOR inhibition impairs autophagy flux and induces cell death independent of apoptosis and necroptosis. Oncotarget. 2016;7:5157-75 pubmed publisher
  48. Wang S, Ni H, Dorko K, Kumer S, Schmitt T, Nawabi A, et al. Increased hepatic receptor interacting protein kinase 3 expression due to impaired proteasomal functions contributes to alcohol-induced steatosis and liver injury. Oncotarget. 2016;7:17681-98 pubmed publisher
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