This is a Validated Antibody Database (VAD) review about human RICTOR, based on 54 published articles (read how Labome selects the articles), using RICTOR antibody in all methods. It is aimed to help Labome visitors find the most suited RICTOR antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
RICTOR synonym: AVO3; PIA; hAVO3

Knockout validation
Cell Signaling Technology
domestic rabbit monoclonal (53A2)
  • western blot knockout validation; mouse; 1:1000; loading ...; fig 1s1b
Cell Signaling Technology RICTOR antibody (CST, 2114) was used in western blot knockout validation on mouse samples at 1:1000 (fig 1s1b). elife (2020) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (53A2)
  • western blot knockout validation; mouse; 1:1000; loading ...; fig ev1 a
Cell Signaling Technology RICTOR antibody (Cell Signaling, cs-2114) was used in western blot knockout validation on mouse samples at 1:1000 (fig ev1 a). EMBO Mol Med (2016) ncbi
Santa Cruz Biotechnology
mouse monoclonal (H-11)
  • western blot; human; 1:2000; loading ...; fig 2b
  • western blot; mouse; 1:2000; loading ...; fig 1e
Santa Cruz Biotechnology RICTOR antibody (Santa CRuz, sc-271081) was used in western blot on human samples at 1:2000 (fig 2b) and in western blot on mouse samples at 1:2000 (fig 1e). iScience (2022) ncbi
mouse monoclonal (H-11)
  • western blot; human; loading ...; fig s7
Santa Cruz Biotechnology RICTOR antibody (Santa, sc-271081) was used in western blot on human samples (fig s7). Cells (2019) ncbi
mouse monoclonal (H-11)
  • western blot; mouse; fig s5b
Santa Cruz Biotechnology RICTOR antibody (Santa Cruz, H-11) was used in western blot on mouse samples (fig s5b). Immunity (2017) ncbi
mouse monoclonal
  • western blot; mouse; fig s5b
Santa Cruz Biotechnology RICTOR antibody (Santa Cruz, H-11) was used in western blot on mouse samples (fig s5b). Immunity (2017) ncbi
mouse monoclonal (H-11)
  • western blot; human; fig 2
Santa Cruz Biotechnology RICTOR antibody (Santa Cruz, sc-271081) was used in western blot on human samples (fig 2). PLoS ONE (2016) ncbi
mouse monoclonal (H-11)
  • western blot; mouse; fig 8
Santa Cruz Biotechnology RICTOR antibody (Santa Cruz Biotechnology, sc-271081) was used in western blot on mouse samples (fig 8). J Biol Chem (2014) ncbi
Invitrogen
mouse monoclonal (7B3)
  • western blot; human; 1:1000; loading ...; fig 5g
Invitrogen RICTOR antibody (Invitrogen, MA5-15681) was used in western blot on human samples at 1:1000 (fig 5g). Nat Commun (2019) ncbi
mouse monoclonal (7B3)
  • western blot; human; loading ...; fig 4b
In order to propose that intracellular localization aids in the regulation of mTORC2 activity toward Akt, Invitrogen RICTOR antibody (Thermo Fisher, MA-5-15681) was used in western blot on human samples (fig 4b). J Cell Biol (2017) ncbi
Abcam
domestic rabbit polyclonal
  • western blot; mouse; fig s5b
Abcam RICTOR antibody (Abcam, ab70374) was used in western blot on mouse samples (fig s5b). Immunity (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...
In order to show that pituitary tumor transforming gene 1 expression is upregulated in an mammalian/mechanistic target of rapamycin complex 1-dependent manner, Abcam RICTOR antibody (Abcam, ab70374) was used in western blot on human samples . Oncogene (2017) ncbi
Abnova
mouse monoclonal (1F3)
  • proximity ligation assay; human; loading ...; fig s7
In order to examine the role of mammalian target of rapamycin in adipocytes, Abnova RICTOR antibody (Abnova, H00253260-M01) was used in proximity ligation assay on human samples (fig s7). Proc Natl Acad Sci U S A (2016) ncbi
Novus Biologicals
mouse monoclonal (7B3)
  • flow cytometry; mouse; 1:66; loading ...; fig s1a
Novus Biologicals RICTOR antibody (NOVOUS BIOLOGICALS, NBP1-51645PE) was used in flow cytometry on mouse samples at 1:66 (fig s1a). Nat Commun (2018) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D16H9)
  • western blot; human; 1:1000; loading ...; fig 12
Cell Signaling Technology RICTOR antibody (Cell Signaling, 9476) was used in western blot on human samples at 1:1000 (fig 12). Int J Oncol (2022) ncbi
domestic rabbit monoclonal (53A2)
  • western blot; human; loading ...; fig 3d
Cell Signaling Technology RICTOR antibody (Cell Signaling, 2114) was used in western blot on human samples (fig 3d). Cell Death Dis (2021) ncbi
domestic rabbit monoclonal (53A2)
  • western blot; mouse; 1:500; loading ...; fig s1d
  • western blot; human; 1:500; loading ...; fig s1d
Cell Signaling Technology RICTOR antibody (Cell Signaling, 2114) was used in western blot on mouse samples at 1:500 (fig s1d) and in western blot on human samples at 1:500 (fig s1d). Mol Cancer (2021) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...
Cell Signaling Technology RICTOR antibody (Cell Signaling Technology, 2140) was used in western blot on human samples at 1:1000. Nat Commun (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 6c
Cell Signaling Technology RICTOR antibody (Cell Signaling Technology, 2140) was used in western blot on mouse samples (fig 6c). J Cell Mol Med (2020) ncbi
domestic rabbit monoclonal (53A2)
  • western blot; human; loading ...; fig 2b
Cell Signaling Technology RICTOR antibody (Cell Signaling, 2114) was used in western blot on human samples (fig 2b). BMC Cancer (2020) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 2c
Cell Signaling Technology RICTOR antibody (Cell Signaling Technology, 2140) was used in western blot on human samples (fig 2c). Cell (2020) ncbi
domestic rabbit monoclonal (53A2)
  • western blot knockout validation; mouse; 1:1000; loading ...; fig 1s1b
Cell Signaling Technology RICTOR antibody (CST, 2114) was used in western blot knockout validation on mouse samples at 1:1000 (fig 1s1b). elife (2020) ncbi
domestic rabbit monoclonal (53A2)
  • western blot; mouse; loading ...; fig 6a
Cell Signaling Technology RICTOR antibody (Cell Signaling Technologies, 2114) was used in western blot on mouse samples (fig 6a). Life Sci (2019) ncbi
domestic rabbit monoclonal (53A2)
  • western blot; human; 1:1000; loading ...; fig 5d
Cell Signaling Technology RICTOR antibody (Cell Signaling, 2114) was used in western blot on human samples at 1:1000 (fig 5d). Int J Biol Sci (2019) ncbi
domestic rabbit monoclonal (53A2)
  • western blot; human; loading ...; fig 7b
Cell Signaling Technology RICTOR antibody (Cell Signaling Technology, 2114) was used in western blot on human samples (fig 7b). J Clin Invest (2019) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; 1:200; loading ...; fig 5c
  • western blot; mouse; 1:1000; loading ...; fig 5a
Cell Signaling Technology RICTOR antibody (Cell Signaling, 2140) was used in immunohistochemistry on mouse samples at 1:200 (fig 5c) and in western blot on mouse samples at 1:1000 (fig 5a). Nature (2019) ncbi
domestic rabbit monoclonal (53A2)
  • western blot; mouse; 1:1000; loading ...; fig s1b
Cell Signaling Technology RICTOR antibody (Cell Signaling, 2114) was used in western blot on mouse samples at 1:1000 (fig s1b). Nat Commun (2018) ncbi
domestic rabbit monoclonal (D16H9)
  • immunoprecipitation; mouse; 1:100; loading ...; fig 9i
  • western blot; mouse; 1:1000; loading ...; fig 9i
Cell Signaling Technology RICTOR antibody (Cell Signaling, 9476) was used in immunoprecipitation on mouse samples at 1:100 (fig 9i) and in western blot on mouse samples at 1:1000 (fig 9i). Nature (2018) ncbi
domestic rabbit monoclonal (53A2)
  • western blot; human; 1:1000; loading ...; fig 3b
Cell Signaling Technology RICTOR antibody (CST, 2114S) was used in western blot on human samples at 1:1000 (fig 3b). Sci Adv (2018) ncbi
domestic rabbit monoclonal (53A2)
  • other; human; loading ...; fig 4c
Cell Signaling Technology RICTOR antibody (Cell Signaling, 2114) was used in other on human samples (fig 4c). Cancer Cell (2018) ncbi
domestic rabbit monoclonal (D30A3)
  • other; human; loading ...; fig 4c
Cell Signaling Technology RICTOR antibody (Cell Signaling, 3806) was used in other on human samples (fig 4c). Cancer Cell (2018) ncbi
domestic rabbit monoclonal (D16H9)
  • western blot; human; loading ...; fig 1d
Cell Signaling Technology RICTOR antibody (Cell signaling, 9476) was used in western blot on human samples (fig 1d). Nature (2017) ncbi
domestic rabbit monoclonal (53A2)
  • immunohistochemistry; mouse; loading ...; fig 7e
In order to demonstrate that WHSC1 drives indolent PTEN-null tumors to become metastatic prostate cancer, Cell Signaling Technology RICTOR antibody (Cell Signaling, 2114) was used in immunohistochemistry on mouse samples (fig 7e). J Clin Invest (2017) ncbi
domestic rabbit monoclonal (53A2)
  • western blot; human; loading ...; fig 2b
Cell Signaling Technology RICTOR antibody (Cell Signaling, 2114) was used in western blot on human samples (fig 2b). Sci Rep (2017) ncbi
domestic rabbit monoclonal (D30A3)
  • reverse phase protein lysate microarray; human; loading ...; fig st6
In order to characterize the molecular identity of uterine carcinosarcomas., Cell Signaling Technology RICTOR antibody (CST, 3806) was used in reverse phase protein lysate microarray on human samples (fig st6). Cancer Cell (2017) ncbi
domestic rabbit monoclonal (53A2)
  • reverse phase protein lysate microarray; human; loading ...; fig st6
In order to characterize the molecular identity of uterine carcinosarcomas., Cell Signaling Technology RICTOR antibody (CST, 2114) was used in reverse phase protein lysate microarray on human samples (fig st6). Cancer Cell (2017) ncbi
domestic rabbit monoclonal (D16H9)
  • western blot; mouse; fig 1c
Cell Signaling Technology RICTOR antibody (Cell Signaling, 9476) was used in western blot on mouse samples (fig 1c). J Biol Chem (2017) ncbi
domestic rabbit monoclonal (D30A3)
  • reverse phase protein lysate microarray; human; loading ...; fig 3a
In order to describe the features of 228 primary cervical cancers, Cell Signaling Technology RICTOR antibody (Cell Signaling, 3806) was used in reverse phase protein lysate microarray on human samples (fig 3a). Nature (2017) ncbi
domestic rabbit monoclonal (53A2)
  • reverse phase protein lysate microarray; human; loading ...; fig 3a
In order to describe the features of 228 primary cervical cancers, Cell Signaling Technology RICTOR antibody (Cell Signaling, 2114) was used in reverse phase protein lysate microarray on human samples (fig 3a). Nature (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig s3g
In order to elucidate that mTORC1 presents tumor suppressor features in conditions of nutrient restrictions, Cell Signaling Technology RICTOR antibody (Cell Signaling, 2140) was used in western blot on human samples at 1:1000 (fig s3g). Nat Commun (2017) ncbi
domestic rabbit monoclonal (53A2)
  • western blot; mouse; 1:1000; loading ...; fig 9e
Cell Signaling Technology RICTOR antibody (Cell Signaling, 2114) was used in western blot on mouse samples at 1:1000 (fig 9e). J Neurosci (2017) ncbi
domestic rabbit monoclonal (53A2)
  • western blot; mouse; loading ...; fig 6b
In order to confirm that FBXL5 contributes to regulation of neural stem-progenitor cells proliferation during mammalian brain development, Cell Signaling Technology RICTOR antibody (CST, 2114) was used in western blot on mouse samples (fig 6b). Mol Cell Biol (2017) ncbi
domestic rabbit monoclonal (D30A3)
  • western blot; human; loading ...
In order to analyze the context specificity of signaling networks within a causal conceptual framework using reverse-phase protein array time-course assays and network analysis approaches, Cell Signaling Technology RICTOR antibody (Cell Signaling Technology, 3806) was used in western blot on human samples . Cell Syst (2017) ncbi
domestic rabbit monoclonal (53A2)
  • western blot; rat; loading ...; fig 2f
  • western blot; mouse; loading ...; fig 2e
Cell Signaling Technology RICTOR antibody (Cell Signalling, 2114) was used in western blot on rat samples (fig 2f) and in western blot on mouse samples (fig 2e). Hum Mol Genet (2017) ncbi
domestic rabbit monoclonal (53A2)
  • western blot; human; 1:1000; loading ...; fig 6a
Cell Signaling Technology RICTOR antibody (Cell Signaling, 2114) was used in western blot on human samples at 1:1000 (fig 6a). Oncotarget (2017) ncbi
domestic rabbit monoclonal (53A2)
  • western blot; human; loading ...; fig 2b
Cell Signaling Technology RICTOR antibody (Cell Signaling, 2114) was used in western blot on human samples (fig 2b). Oncotarget (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 3b
Cell Signaling Technology RICTOR antibody (Cell Signaling Technology, 2140) was used in western blot on human samples (fig 3b). Cell Signal (2017) ncbi
domestic rabbit monoclonal (53A2)
  • western blot; human; 1:1000; fig 1
In order to elucidate the mechanisms by which mutant IDH1/2 contributes to oncogenesis, Cell Signaling Technology RICTOR antibody (Cell signaling, 53A2) was used in western blot on human samples at 1:1000 (fig 1). Nat Commun (2016) ncbi
domestic rabbit monoclonal (D30A3)
  • western blot; human; 1:1000; fig 1
In order to elucidate the mechanisms by which mutant IDH1/2 contributes to oncogenesis, Cell Signaling Technology RICTOR antibody (Cell signaling, D30A3) was used in western blot on human samples at 1:1000 (fig 1). Nat Commun (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 2h
In order to test if mammalian target of rapamycin complex 2 contributes to podocyte injury during diabetes, Cell Signaling Technology RICTOR antibody (Cell Signaling, 2140) was used in western blot on mouse samples at 1:1000 (fig 2h). Antioxid Redox Signal (2016) ncbi
domestic rabbit monoclonal (53A2)
  • immunoprecipitation; human; loading ...; fig 3b
  • western blot; human; loading ...; fig 3b
In order to research the roles of HSF1 and mTORC1 in proteotoxic stress and cell growth, Cell Signaling Technology RICTOR antibody (Cell Signaling, 2114) was used in immunoprecipitation on human samples (fig 3b) and in western blot on human samples (fig 3b). Nat Cell Biol (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; fig 3
Cell Signaling Technology RICTOR antibody (Cell Signaling Technologies, 2140) was used in western blot on human samples at 1:1000 (fig 3). Nat Commun (2016) ncbi
domestic rabbit monoclonal (D16H9)
  • western blot; mouse; fig 5
In order to describe a signaling pathway from beta-adrenergic receptor and protein kinase A via mTORC1 that is required for adipose browning by catecholamines, Cell Signaling Technology RICTOR antibody (Cell Signaling, 9476) was used in western blot on mouse samples (fig 5). J Clin Invest (2016) ncbi
domestic rabbit monoclonal (53A2)
  • western blot knockout validation; mouse; 1:1000; loading ...; fig ev1 a
Cell Signaling Technology RICTOR antibody (Cell Signaling, cs-2114) was used in western blot knockout validation on mouse samples at 1:1000 (fig ev1 a). EMBO Mol Med (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000
Cell Signaling Technology RICTOR antibody (Cell Signaling, 2140) was used in western blot on mouse samples at 1:1000. Nat Commun (2016) ncbi
domestic rabbit monoclonal (53A2)
  • western blot; human; fig 6
Cell Signaling Technology RICTOR antibody (Cell Signaling, 2114) was used in western blot on human samples (fig 6). PLoS ONE (2015) ncbi
domestic rabbit monoclonal (D16H9)
  • immunohistochemistry - paraffin section; mouse; 1:50; fig 1a
  • western blot; mouse; 1:2000; fig 1f
Cell Signaling Technology RICTOR antibody (Cell Signaling Technology, 9476) was used in immunohistochemistry - paraffin section on mouse samples at 1:50 (fig 1a) and in western blot on mouse samples at 1:2000 (fig 1f). Endocrinology (2015) ncbi
domestic rabbit monoclonal (D16H9)
  • western blot; human; fig 3
Cell Signaling Technology RICTOR antibody (Cell Signaling, 9476S) was used in western blot on human samples (fig 3). PLoS ONE (2015) ncbi
domestic rabbit monoclonal (53A2)
  • immunohistochemistry; human; loading ...; fig 2c
  • western blot; mouse; loading ...; fig 1d
Cell Signaling Technology RICTOR antibody (Cell Signaling, 53A2) was used in immunohistochemistry on human samples (fig 2c) and in western blot on mouse samples (fig 1d). EMBO Rep (2015) ncbi
domestic rabbit monoclonal (D16H9)
  • western blot; mouse
  • western blot; human
In order to show that FKBP12 and FKBP51 levels determine the responsiveness of a cell line or tissue to rapamycin, Cell Signaling Technology RICTOR antibody (Cell Signaling, #9476) was used in western blot on mouse samples and in western blot on human samples . Aging Cell (2015) ncbi
domestic rabbit monoclonal (53A2)
  • western blot; human; fig 1
  • western blot; mouse; fig 3h
Cell Signaling Technology RICTOR antibody (Cell Signaling Technology, 2114) was used in western blot on human samples (fig 1) and in western blot on mouse samples (fig 3h). Oncotarget (2014) ncbi
domestic rabbit monoclonal (53A2)
  • western blot; mouse; fig 3
Cell Signaling Technology RICTOR antibody (Cell Signaling, 2114) was used in western blot on mouse samples (fig 3). Autophagy (2014) ncbi
domestic rabbit monoclonal (D16H9)
  • western blot; mouse
In order to study the regulation of adipogenesis by mechanical strain in mesenchymal stem cells and the roles played by Fyn, mTORC2 and RhoA, Cell Signaling Technology RICTOR antibody (Cell Signaling, D16H9) was used in western blot on mouse samples . Stem Cells (2013) ncbi
Articles Reviewed
  1. Serna R, Ramrakhiani A, Hernández J, Chen C, Nakagawa C, Machida T, et al. c-JUN inhibits mTORC2 and glucose uptake to promote self-renewal and obesity. iScience. 2022;25:104325 pubmed publisher
  2. Geng F, Yang W, Song D, Hou H, Han B, Chen Y, et al. MDIG, a 2‑oxoglutarate‑dependent oxygenase, acts as an oncogene and predicts the prognosis of multiple types of cancer. Int J Oncol. 2022;61: pubmed publisher
  3. Chen X, Miao M, Zhou M, Chen J, Li D, Zhang L, et al. Poly-L-arginine promotes asthma angiogenesis through induction of FGFBP1 in airway epithelial cells via activation of the mTORC1-STAT3 pathway. Cell Death Dis. 2021;12:761 pubmed publisher
  4. Yan C, Saleh N, Yang J, Nebhan C, Vilgelm A, Reddy E, et al. Novel induction of CD40 expression by tumor cells with RAS/RAF/PI3K pathway inhibition augments response to checkpoint blockade. Mol Cancer. 2021;20:85 pubmed publisher
  5. Zhang Y, Swanda R, Nie L, Liu X, Wang C, Lee H, et al. mTORC1 couples cyst(e)ine availability with GPX4 protein synthesis and ferroptosis regulation. Nat Commun. 2021;12:1589 pubmed publisher
  6. Zhao L, Fan M, Zhao L, Yun H, Yang Y, Wang C, et al. Fibroblast growth factor 1 ameliorates adipose tissue inflammation and systemic insulin resistance via enhancing adipocyte mTORC2/Rictor signal. J Cell Mol Med. 2020;24:12813-12825 pubmed publisher
  7. Saurabh K, Shah P, Doll M, Siskind L, Beverly L. UBR-box containing protein, UBR5, is over-expressed in human lung adenocarcinoma and is a potential therapeutic target. BMC Cancer. 2020;20:824 pubmed publisher
  8. Koundouros N, Karali E, Tripp A, Valle A, Inglese P, Perry N, et al. Metabolic Fingerprinting Links Oncogenic PIK3CA with Enhanced Arachidonic Acid-Derived Eicosanoids. Cell. 2020;181:1596-1611.e27 pubmed publisher
  9. McCabe M, Cullen E, Barrows C, Shore A, Tooke K, Laprade K, et al. Genetic inactivation of mTORC1 or mTORC2 in neurons reveals distinct functions in glutamatergic synaptic transmission. elife. 2020;9: pubmed publisher
  10. Barbero G, Castro M, Villanueva M, Quezada M, Fernández N, Demorrow S, et al. An Autocrine Wnt5a Loop Promotes NF-κB Pathway Activation and Cytokine/Chemokine Secretion in Melanoma. Cells. 2019;8: pubmed publisher
  11. Gao H, Freeling J, Wu P, Liang A, Wang X, Li Y. UCHL1 regulates muscle fibers and mTORC1 activity in skeletal muscle. Life Sci. 2019;233:116699 pubmed publisher
  12. Wang H, Huang F, Zhang Z, Wang P, Luo Y, Li H, et al. Feedback Activation of SGK3 and AKT Contributes to Rapamycin Resistance by Reactivating mTORC1/4EBP1 Axis via TSC2 in Breast Cancer. Int J Biol Sci. 2019;15:929-941 pubmed publisher
  13. Mathieu J, Detraux D, Kuppers D, Wang Y, Cavanaugh C, Sidhu S, et al. Folliculin regulates mTORC1/2 and WNT pathways in early human pluripotency. Nat Commun. 2019;10:632 pubmed publisher
  14. Wang W, Shen T, Dong B, Creighton C, Meng Y, Zhou W, et al. MAPK4 overexpression promotes tumor progression via noncanonical activation of AKT/mTOR signaling. J Clin Invest. 2019;: pubmed publisher
  15. Poulopoulos A, Murphy A, Ozkan A, Davis P, Hatch J, Kirchner R, et al. Subcellular transcriptomes and proteomes of developing axon projections in the cerebral cortex. Nature. 2019;565:356-360 pubmed publisher
  16. Wang F, Meng M, Mo B, Yang Y, Ji Y, Huang P, et al. Crosstalks between mTORC1 and mTORC2 variagate cytokine signaling to control NK maturation and effector function. Nat Commun. 2018;9:4874 pubmed publisher
  17. Rapino F, Delaunay S, Rambow F, Zhou Z, Tharun L, de Tullio P, et al. Codon-specific translation reprogramming promotes resistance to targeted therapy. Nature. 2018;558:605-609 pubmed publisher
  18. NGUYEN J, Ray C, Fox A, Mendonça D, Kim J, Krebsbach P. Mammalian EAK-7 activates alternative mTOR signaling to regulate cell proliferation and migration. Sci Adv. 2018;4:eaao5838 pubmed publisher
  19. Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  20. Kishore M, Cheung K, Fu H, Bonacina F, Wang G, Coe D, et al. Regulatory T Cell Migration Is Dependent on Glucokinase-Mediated Glycolysis. Immunity. 2017;47:875-889.e10 pubmed publisher
  21. Wang B, Jie Z, Joo D, Ordureau A, Liu P, Gan W, et al. TRAF2 and OTUD7B govern a ubiquitin-dependent switch that regulates mTORC2 signalling. Nature. 2017;545:365-369 pubmed publisher
  22. Li N, Xue W, Yuan H, Dong B, Ding Y, Liu Y, et al. AKT-mediated stabilization of histone methyltransferase WHSC1 promotes prostate cancer metastasis. J Clin Invest. 2017;127:1284-1302 pubmed publisher
  23. Merhi A, Delree P, Marini A. The metabolic waste ammonium regulates mTORC2 and mTORC1 signaling. Sci Rep. 2017;7:44602 pubmed publisher
  24. Cherniack A, Shen H, Walter V, Stewart C, Murray B, Bowlby R, et al. Integrated Molecular Characterization of Uterine Carcinosarcoma. Cancer Cell. 2017;31:411-423 pubmed publisher
  25. Jacobs B, McNally R, Kim K, Blanco R, Privett R, You J, et al. Identification of mechanically regulated phosphorylation sites on tuberin (TSC2) that control mechanistic target of rapamycin (mTOR) signaling. J Biol Chem. 2017;292:6987-6997 pubmed publisher
  26. Ebner M, Sinkovics B, Szczygieł M, Ribeiro D, Yudushkin I. Localization of mTORC2 activity inside cells. J Cell Biol. 2017;216:343-353 pubmed publisher
  27. . Integrated genomic and molecular characterization of cervical cancer. Nature. 2017;543:378-384 pubmed publisher
  28. Villar V, Nguyen T, Delcroix V, Terés S, Bouchecareilh M, Salin B, et al. mTORC1 inhibition in cancer cells protects from glutaminolysis-mediated apoptosis during nutrient limitation. Nat Commun. 2017;8:14124 pubmed publisher
  29. Hussain R, Macklin W. Integrin-Linked Kinase (ILK) Deletion Disrupts Oligodendrocyte Development by Altering Cell Cycle. J Neurosci. 2017;37:397-412 pubmed publisher
  30. Yamauchi T, Nishiyama M, Moroishi T, Kawamura A, Nakayama K. FBXL5 Inactivation in Mouse Brain Induces Aberrant Proliferation of Neural Stem Progenitor Cells. Mol Cell Biol. 2017;37: pubmed publisher
  31. Hill S, Nesser N, Johnson Camacho K, Jeffress M, Johnson A, Boniface C, et al. Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling. Cell Syst. 2017;4:73-83.e10 pubmed publisher
  32. Jin F, Jiang K, Ji S, Wang L, Ni Z, Huang F, et al. Deficient TSC1/TSC2-complex suppression of SOX9-osteopontin-AKT signalling cascade constrains tumour growth in tuberous sclerosis complex. Hum Mol Genet. 2017;26:407-419 pubmed publisher
  33. Fourneaux B, Chaire V, Lucchesi C, Karanian M, Pineau R, Laroche Clary A, et al. Dual inhibition of the PI3K/AKT/mTOR pathway suppresses the growth of leiomyosarcomas but leads to ERK activation through mTORC2: biological and clinical implications. Oncotarget. 2017;8:7878-7890 pubmed publisher
  34. Sakre N, Wildey G, Behtaj M, Kresak A, Yang M, Fu P, et al. RICTOR amplification identifies a subgroup in small cell lung cancer and predicts response to drugs targeting mTOR. Oncotarget. 2017;8:5992-6002 pubmed publisher
  35. Hau A, Leivo M, Gilder A, Hu J, Gonias S, Hansel D. mTORC2 activation is regulated by the urokinase receptor (uPAR) in bladder cancer. Cell Signal. 2017;29:96-106 pubmed publisher
  36. Carbonneau M, M Gagné L, Lalonde M, Germain M, Motorina A, Guiot M, et al. The oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathway. Nat Commun. 2016;7:12700 pubmed publisher
  37. Chen R, Duan J, Li L, Ma Q, Sun Q, Ma J, et al. mTOR promotes pituitary tumor development through activation of PTTG1. Oncogene. 2017;36:979-988 pubmed publisher
  38. Eid S, Boutary S, Braych K, Sabra R, Massaad C, Hamdy A, et al. mTORC2 Signaling Regulates Nox4-Induced Podocyte Depletion in Diabetes. Antioxid Redox Signal. 2016;25:703-719 pubmed
  39. Wu X, Schneider N, Platen A, Mitra I, Blazek M, Zengerle R, et al. In situ characterization of the mTORC1 during adipogenesis of human adult stem cells on chip. Proc Natl Acad Sci U S A. 2016;113:E4143-50 pubmed publisher
  40. Cui Y, Zhao J, Yi L, Jiang Y. microRNA-153 Targets mTORC2 Component Rictor to Inhibit Glioma Cells. PLoS ONE. 2016;11:e0156915 pubmed publisher
  41. Su K, Cao J, Tang Z, Dai S, He Y, Sampson S, et al. HSF1 critically attunes proteotoxic stress sensing by mTORC1 to combat stress and promote growth. Nat Cell Biol. 2016;18:527-39 pubmed publisher
  42. Gandin V, Masvidal L, Cargnello M, Gyenis L, McLaughlan S, Cai Y, et al. mTORC1 and CK2 coordinate ternary and eIF4F complex assembly. Nat Commun. 2016;7:11127 pubmed publisher
  43. Liu D, Bordicchia M, Zhang C, Fang H, Wei W, Li J, et al. Activation of mTORC1 is essential for ?-adrenergic stimulation of adipose browning. J Clin Invest. 2016;126:1704-16 pubmed publisher
  44. Albert V, Svensson K, Shimobayashi M, Colombi M, Munoz S, Jimenez V, et al. mTORC2 sustains thermogenesis via Akt-induced glucose uptake and glycolysis in brown adipose tissue. EMBO Mol Med. 2016;8:232-46 pubmed publisher
  45. Kim K, Qiang L, Hayden M, Sparling D, Purcell N, Pajvani U. mTORC1-independent Raptor prevents hepatic steatosis by stabilizing PHLPP2. Nat Commun. 2016;7:10255 pubmed publisher
  46. Yasuda K, Takahashi M, Mori N. Mdm20 Modulates Actin Remodeling through the mTORC2 Pathway via Its Effect on Rictor Expression. PLoS ONE. 2015;10:e0142943 pubmed publisher
  47. Dong H, Chen Z, Wang C, Xiong Z, Zhao W, Jia C, et al. Rictor Regulates Spermatogenesis by Controlling Sertoli Cell Cytoskeletal Organization and Cell Polarity in the Mouse Testis. Endocrinology. 2015;156:4244-56 pubmed publisher
  48. Jiang S, Zou Z, Nie P, Wen R, Xiao Y, Tang J. Synergistic Effects between mTOR Complex 1/2 and Glycolysis Inhibitors in Non-Small-Cell Lung Carcinoma Cells. PLoS ONE. 2015;10:e0132880 pubmed publisher
  49. Zidek L, Ackermann T, Hartleben G, Eichwald S, Kortman G, Kiehntopf M, et al. Deficiency in mTORC1-controlled C/EBPβ-mRNA translation improves metabolic health in mice. EMBO Rep. 2015;16:1022-36 pubmed publisher
  50. Schreiber K, Ortiz D, Academia E, Anies A, Liao C, Kennedy B. Rapamycin-mediated mTORC2 inhibition is determined by the relative expression of FK506-binding proteins. Aging Cell. 2015;14:265-73 pubmed publisher
  51. Kazyken D, Kaz Y, Kiyan V, Zhylkibayev A, Chen C, Agarwal N, et al. The nuclear import of ribosomal proteins is regulated by mTOR. Oncotarget. 2014;5:9577-93 pubmed
  52. Zhang D, Tong X, Arthurs B, Guha A, Rui L, Kamath A, et al. Liver clock protein BMAL1 promotes de novo lipogenesis through insulin-mTORC2-AKT signaling. J Biol Chem. 2014;289:25925-35 pubmed publisher
  53. Tan S, Shui G, Zhou J, Shi Y, Huang J, Xia D, et al. Critical role of SCD1 in autophagy regulation via lipogenesis and lipid rafts-coupled AKT-FOXO1 signaling pathway. Autophagy. 2014;10:226-42 pubmed publisher
  54. Thompson W, Guilluy C, Xie Z, Sen B, Brobst K, Yen S, et al. Mechanically activated Fyn utilizes mTORC2 to regulate RhoA and adipogenesis in mesenchymal stem cells. Stem Cells. 2013;31:2528-37 pubmed publisher