This is a Validated Antibody Database (VAD) review about human RBX1, based on 7 published articles (read how Labome selects the articles), using RBX1 antibody in all methods. It is aimed to help Labome visitors find the most suited RBX1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
RBX1 synonym: BA554C12.1; RNF75; ROC1; E3 ubiquitin-protein ligase RBX1; E3 ubiquitin-protein transferase RBX1; RING finger protein 75; RING-box protein 1; ZYP protein; regulator of cullins 1; ring-box 1, E3 ubiquitin protein ligase

Invitrogen
rabbit polyclonal
  • western blot; human; 1:300; loading ...; fig 2a
In order to identify and characterize an inhibitor of the COP9 signalosome, Invitrogen RBX1 antibody (Invitrogen, 342500) was used in western blot on human samples at 1:300 (fig 2a). Nat Commun (2016) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 1a
In order to investigate the phosphorylation and ubiquitylation of autoimmune regulator, Invitrogen RBX1 antibody (Invitrogen, 34-2500) was used in western blot on human samples (fig 1a). J Biol Chem (2016) ncbi
Abcam
rabbit polyclonal
  • immunoprecipitation; budding yeasts
  • western blot; budding yeasts
Abcam RBX1 antibody (Abcam, ab2977) was used in immunoprecipitation on budding yeasts samples and in western blot on budding yeasts samples . Nat Commun (2014) ncbi
Cell Signaling Technology
rabbit monoclonal (D3J5I)
  • western blot; human; 1:500; loading ...; fig s2j
Cell Signaling Technology RBX1 antibody (Cell Signaling, 11922) was used in western blot on human samples at 1:500 (fig s2j). Nat Commun (2018) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 2b
In order to determine the rotavirus NSP1-host protein interaction network, Cell Signaling Technology RBX1 antibody (CST, 4397) was used in western blot on human samples (fig 2b). PLoS Pathog (2016) ncbi
rabbit monoclonal (D3J5I)
  • western blot; mouse; loading ...
Cell Signaling Technology RBX1 antibody (Cell signaling, 11922) was used in western blot on mouse samples . elife (2016) ncbi
rabbit monoclonal (D3J5I)
  • western blot; human; 1:2000; fig 4
In order to report the contribution of DYRK1A and DYRK1B in cancer stem cells, Cell Signaling Technology RBX1 antibody (Cell Signaling Technology, 11922) was used in western blot on human samples at 1:2000 (fig 4). Nature (2016) ncbi
Articles Reviewed
  1. Yao F, Zhou Z, Kim J, Hang Q, Xiao Z, Ton B, et al. SKP2- and OTUD1-regulated non-proteolytic ubiquitination of YAP promotes YAP nuclear localization and activity. Nat Commun. 2018;9:2269 pubmed publisher
  2. Schlierf A, Altmann E, Quancard J, Jefferson A, Assenberg R, Renatus M, et al. Targeted inhibition of the COP9 signalosome for treatment of cancer. Nat Commun. 2016;7:13166 pubmed publisher
  3. Ding S, Mooney N, Li B, Kelly M, Feng N, Loktev A, et al. Comparative Proteomics Reveals Strain-Specific ?-TrCP Degradation via Rotavirus NSP1 Hijacking a Host Cullin-3-Rbx1 Complex. PLoS Pathog. 2016;12:e1005929 pubmed publisher
  4. Shao W, Zumer K, Fujinaga K, Peterlin B. FBXO3 Protein Promotes Ubiquitylation and Transcriptional Activity of AIRE (Autoimmune Regulator). J Biol Chem. 2016;291:17953-63 pubmed publisher
  5. Yu Z, Chen T, Li X, Yang M, Tang S, Zhu X, et al. Lys29-linkage of ASK1 by Skp1-Cullin 1-Fbxo21 ubiquitin ligase complex is required for antiviral innate response. elife. 2016;5: pubmed publisher
  6. Lee S, Frattini V, Bansal M, Castano A, Sherman D, Hutchinson K, et al. An ID2-dependent mechanism for VHL inactivation in cancer. Nature. 2016;529:172-7 pubmed publisher
  7. Xie P, Zhang M, He S, Lu K, Chen Y, Xing G, et al. The covalent modifier Nedd8 is critical for the activation of Smurf1 ubiquitin ligase in tumorigenesis. Nat Commun. 2014;5:3733 pubmed publisher