This is a Validated Antibody Database (VAD) review about human RBBP8, based on 28 published articles (read how Labome selects the articles), using RBBP8 antibody in all methods. It is aimed to help Labome visitors find the most suited RBBP8 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
RBBP8 synonym: COM1; CTIP; JWDS; RIM; SAE2; SCKL2; DNA endonuclease RBBP8; CTBP-interacting protein; RBBP-8; retinoblastoma binding protein 8; sporulation in the absence of SPO11 protein 2 homolog

Active Motif
mouse monoclonal (14-1)
  • western blot; human; loading ...; fig s6a
In order to describe a unique replication-dependent repair pathway that leads to the mitochondrial common deletion, Active Motif RBBP8 antibody (Active motif, 61141) was used in western blot on human samples (fig s6a). Mol Cell (2017) ncbi
mouse monoclonal (14-1)
  • western blot; human; loading ...; fig 2b
Active Motif RBBP8 antibody (Active Motif, 14-1) was used in western blot on human samples (fig 2b). Nat Commun (2016) ncbi
mouse monoclonal (14-1)
  • immunocytochemistry; human; loading ...; fig 3b
  • western blot; human; loading ...; fig 4b
Active Motif RBBP8 antibody (Active Motif, 61141) was used in immunocytochemistry on human samples (fig 3b) and in western blot on human samples (fig 4b). Oncotarget (2016) ncbi
mouse monoclonal (14-1)
  • immunocytochemistry; human; loading ...; fig 4e
Active Motif RBBP8 antibody (Active Motif, 14-1) was used in immunocytochemistry on human samples (fig 4e). Cell Rep (2016) ncbi
mouse monoclonal (14-1)
  • western blot; human; fig 1
Active Motif RBBP8 antibody (Active Motif, 61141) was used in western blot on human samples (fig 1). Nucleic Acids Res (2016) ncbi
mouse monoclonal (14-1)
  • immunocytochemistry; human; fig 7
Active Motif RBBP8 antibody (Active motif, 14-1) was used in immunocytochemistry on human samples (fig 7). PLoS Genet (2016) ncbi
mouse monoclonal (14-1)
  • immunocytochemistry; human; 1:500; fig 4
Active Motif RBBP8 antibody (Active Motif, 61141) was used in immunocytochemistry on human samples at 1:500 (fig 4). Nat Commun (2016) ncbi
mouse monoclonal (14-1)
  • western blot; human
Active Motif RBBP8 antibody (Active Motif, 61141) was used in western blot on human samples . Nucleic Acids Res (2014) ncbi
Bethyl
rabbit polyclonal
  • western blot; human; 1:1000; fig s4
In order to study APC/C(Cdh1) function, Bethyl RBBP8 antibody (Bethyl Laboratories, A300-488A) was used in western blot on human samples at 1:1000 (fig s4). Nucleic Acids Res (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 2b
Bethyl RBBP8 antibody (Bethyl Laboratories, A300-488A) was used in western blot on human samples (fig 2b). Nucleic Acids Res (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 2
Bethyl RBBP8 antibody (Bethyl Laboratories, A300-488A) was used in western blot on human samples (fig 2). Nucleic Acids Res (2015) ncbi
rabbit polyclonal
  • western blot; human; fig 5
Bethyl RBBP8 antibody (Bethyl Laboratories, A300-488A) was used in western blot on human samples (fig 5). PLoS ONE (2015) ncbi
rabbit polyclonal
  • chromatin immunoprecipitation; human; 1:1000; fig 4
In order to identify a novel DNA2- and WRN-dependent mechanism of reversed replication fork processing and restart after prolonged genotoxic stress, Bethyl RBBP8 antibody (Bethyl, A300-488A) was used in chromatin immunoprecipitation on human samples at 1:1000 (fig 4). J Cell Biol (2015) ncbi
rabbit polyclonal
  • western blot; human; fig 4
Bethyl RBBP8 antibody (Bethyl, A300-488A) was used in western blot on human samples (fig 4). Cell Cycle (2015) ncbi
rabbit polyclonal
  • immunocytochemistry; human; 1:100; fig 2
In order to study double stranded break repair during different stages of the cell cycle, Bethyl RBBP8 antibody (Bethyl, A300-488A) was used in immunocytochemistry on human samples at 1:100 (fig 2). Cell Cycle (2014) ncbi
rabbit polyclonal
  • western blot; African green monkey; fig s3b
Bethyl RBBP8 antibody (Bethyl, A300-488A) was used in western blot on African green monkey samples (fig s3b). PLoS Pathog (2014) ncbi
Abcam
rabbit monoclonal (EPNCIR160)
  • western blot; human; loading ...; fig 5d
Abcam RBBP8 antibody (Abcam, ab155988) was used in western blot on human samples (fig 5d). Genes Dev (2019) ncbi
rabbit polyclonal
  • immunocytochemistry; human; fig 2
Abcam RBBP8 antibody (Abcam, ab70163) was used in immunocytochemistry on human samples (fig 2). Nucleic Acids Res (2016) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; fig 3
Abcam RBBP8 antibody (Abcam, ab70163) was used in western blot on mouse samples at 1:1000 (fig 3). Nature (2015) ncbi
Santa Cruz Biotechnology
mouse monoclonal (D-4)
  • western blot; mouse; 1:500; fig 3
Santa Cruz Biotechnology RBBP8 antibody (Santa, sc271339) was used in western blot on mouse samples at 1:500 (fig 3). Nucleic Acids Res (2015) ncbi
mouse monoclonal (D-4)
  • western blot; human; fig 4
Santa Cruz Biotechnology RBBP8 antibody (Santa Cruz, sc-271339) was used in western blot on human samples (fig 4). Oncogene (2015) ncbi
mouse monoclonal (E-2)
  • western blot; human; 1:1000
In order to study the effect of ASF1 depletion on the alternative lengthening of telomeres, Santa Cruz Biotechnology RBBP8 antibody (Santa, sc-48415) was used in western blot on human samples at 1:1000. Nat Struct Mol Biol (2014) ncbi
mouse monoclonal (D-4)
  • western blot; human; fig 2
Santa Cruz Biotechnology RBBP8 antibody (Santa Cruz, sc-271339) was used in western blot on human samples (fig 2). Nucleic Acids Res (2012) ncbi
GeneTex
mouse monoclonal (19E8)
  • western blot; human; fig 4
GeneTex RBBP8 antibody (GeneTex, 19E8) was used in western blot on human samples (fig 4). Nucleic Acids Res (2016) ncbi
mouse monoclonal (19E8)
  • proximity ligation assay; human; fig 4b
GeneTex RBBP8 antibody (GeneTex, GTX70264) was used in proximity ligation assay on human samples (fig 4b). Nucleic Acids Res (2016) ncbi
Novus Biologicals
rabbit polyclonal
  • immunocytochemistry; human; 1:500; fig s4
  • western blot; human; 1:1000; fig 6
Novus Biologicals RBBP8 antibody (Novus biological, NB100-79810) was used in immunocytochemistry on human samples at 1:500 (fig s4) and in western blot on human samples at 1:1000 (fig 6). Nat Commun (2015) ncbi
Cell Signaling Technology
rabbit monoclonal (D76F7)
  • western blot; human; fig 4d
Cell Signaling Technology RBBP8 antibody (Cell Signaling Technology, 9201) was used in western blot on human samples (fig 4d). Sci Rep (2017) ncbi
rabbit monoclonal (D76F7)
  • immunocytochemistry; mouse; 1:100; fig 1
Cell Signaling Technology RBBP8 antibody (Cell Signaling, 9201) was used in immunocytochemistry on mouse samples at 1:100 (fig 1). Proc Natl Acad Sci U S A (2015) ncbi
rabbit monoclonal (D76F7)
  • immunocytochemistry; human
  • western blot; human
Cell Signaling Technology RBBP8 antibody (Cell Signaling Technology, 9201) was used in immunocytochemistry on human samples and in western blot on human samples . DNA Repair (Amst) (2015) ncbi
Articles Reviewed
  1. Moquin D, Genois M, Zhang J, Ouyang J, Yadav T, Buisson R, et al. Localized protein biotinylation at DNA damage sites identifies ZPET, a repressor of homologous recombination. Genes Dev. 2019;33:75-89 pubmed publisher
  2. Yamauchi M, Shibata A, Suzuki K, Suzuki M, Niimi A, Kondo H, et al. Regulation of pairing between broken DNA-containing chromatin regions by Ku80, DNA-PKcs, ATM, and 53BP1. Sci Rep. 2017;7:41812 pubmed publisher
  3. Phillips A, Millet A, Tigano M, Dubois S, Crimmins H, Babin L, et al. Single-Molecule Analysis of mtDNA Replication Uncovers the Basis of the Common Deletion. Mol Cell. 2017;65:527-538.e6 pubmed publisher
  4. Shamanna R, Lu H, de Freitas J, Tian J, Croteau D, Bohr V. WRN regulates pathway choice between classical and alternative non-homologous end joining. Nat Commun. 2016;7:13785 pubmed publisher
  5. Bakr A, Köcher S, Volquardsen J, Petersen C, Borgmann K, Dikomey E, et al. Impaired 53BP1/RIF1 DSB mediated end-protection stimulates CtIP-dependent end resection and switches the repair to PARP1-dependent end joining in G1. Oncotarget. 2016;7:57679-57693 pubmed publisher
  6. Kais Z, Rondinelli B, Holmes A, O Leary C, Kozono D, D Andrea A, et al. FANCD2 Maintains Fork Stability in BRCA1/2-Deficient Tumors and Promotes Alternative End-Joining DNA Repair. Cell Rep. 2016;15:2488-99 pubmed publisher
  7. Ahrabi S, Sarkar S, Pfister S, Pirovano G, Higgins G, Porter A, et al. A role for human homologous recombination factors in suppressing microhomology-mediated end joining. Nucleic Acids Res. 2016;44:5743-57 pubmed publisher
  8. Onyango D, Howard S, Neherin K, Yanez D, Stark J. Tetratricopeptide repeat factor XAB2 mediates the end resection step of homologous recombination. Nucleic Acids Res. 2016;44:5702-16 pubmed publisher
  9. Ercilla A, Llopis A, Feu S, Aranda S, Ernfors P, Freire R, et al. New origin firing is inhibited by APC/CCdh1 activation in S-phase after severe replication stress. Nucleic Acids Res. 2016;44:4745-62 pubmed publisher
  10. Nagy Z, Kalousi A, Furst A, Koch M, Fischer B, Soutoglou E. Tankyrases Promote Homologous Recombination and Check Point Activation in Response to DSBs. PLoS Genet. 2016;12:e1005791 pubmed publisher
  11. Zhang H, Liu H, Chen Y, Yang X, Wang P, Liu T, et al. A cell cycle-dependent BRCA1-UHRF1 cascade regulates DNA double-strand break repair pathway choice. Nat Commun. 2016;7:10201 pubmed publisher
  12. Baude A, Aaes T, Zhai B, Al Nakouzi N, Oo H, Daugaard M, et al. Hepatoma-derived growth factor-related protein 2 promotes DNA repair by homologous recombination. Nucleic Acids Res. 2016;44:2214-26 pubmed publisher
  13. Saquilabon Cruz G, Kong X, Silva B, Khatibzadeh N, Thai R, Berns M, et al. Femtosecond near-infrared laser microirradiation reveals a crucial role for PARP signaling on factor assemblies at DNA damage sites. Nucleic Acids Res. 2016;44:e27 pubmed publisher
  14. Lee K, Im J, Shibata E, Park J, Handa N, Kowalczykowski S, et al. MCM8-9 complex promotes resection of double-strand break ends by MRE11-RAD50-NBS1 complex. Nat Commun. 2015;6:7744 pubmed publisher
  15. Rein K, Yanez D, Terré B, Palenzuela L, Aivio S, Wei K, et al. EXO1 is critical for embryogenesis and the DNA damage response in mice with a hypomorphic Nbs1 allele. Nucleic Acids Res. 2015;43:7371-87 pubmed publisher
  16. Ahn J, Kim S, Na W, Baek S, Kim J, Min K, et al. SERBP1 affects homologous recombination-mediated DNA repair by regulation of CtIP translation during S phase. Nucleic Acids Res. 2015;43:6321-33 pubmed publisher
  17. Nakajima N, Hagiwara Y, Oike T, Okayasu R, Murakami T, Nakano T, et al. Pre-exposure to ionizing radiation stimulates DNA double strand break end resection, promoting the use of homologous recombination repair. PLoS ONE. 2015;10:e0122582 pubmed publisher
  18. Xu G, Chapman J, Brandsma I, Yuan J, Mistrik M, Bouwman P, et al. REV7 counteracts DNA double-strand break resection and affects PARP inhibition. Nature. 2015;521:541-544 pubmed publisher
  19. Thangavel S, Berti M, Levikova M, Pinto C, Gomathinayagam S, Vujanovic M, et al. DNA2 drives processing and restart of reversed replication forks in human cells. J Cell Biol. 2015;208:545-62 pubmed publisher
  20. Brazina J, Svadlenka J, Macurek L, Andera L, Hodny Z, Bartek J, et al. DNA damage-induced regulatory interplay between DAXX, p53, ATM kinase and Wip1 phosphatase. Cell Cycle. 2015;14:375-87 pubmed publisher
  21. Liu E, Xu N, O Prey J, Lao L, Joshi S, Long J, et al. Loss of autophagy causes a synthetic lethal deficiency in DNA repair. Proc Natl Acad Sci U S A. 2015;112:773-8 pubmed publisher
  22. Xue L, Furusawa Y, Okayasu R, Miura M, Cui X, Liu C, et al. The complexity of DNA double strand break is a crucial factor for activating ATR signaling pathway for G2/M checkpoint regulation regardless of ATM function. DNA Repair (Amst). 2015;25:72-83 pubmed publisher
  23. Averbeck N, Ringel O, Herrlitz M, Jakob B, Durante M, Taucher Scholz G. DNA end resection is needed for the repair of complex lesions in G1-phase human cells. Cell Cycle. 2014;13:2509-16 pubmed publisher
  24. Sowd G, Mody D, Eggold J, Cortez D, Friedman K, Fanning E. SV40 utilizes ATM kinase activity to prevent non-homologous end joining of broken viral DNA replication products. PLoS Pathog. 2014;10:e1004536 pubmed publisher
  25. Hühn D, Kousholt A, Sørensen C, Sartori A. miR-19, a component of the oncogenic miR-17∼92 cluster, targets the DNA-end resection factor CtIP. Oncogene. 2015;34:3977-84 pubmed publisher
  26. O Sullivan R, Arnoult N, Lackner D, Oganesian L, Haggblom C, Corpet A, et al. Rapid induction of alternative lengthening of telomeres by depletion of the histone chaperone ASF1. Nat Struct Mol Biol. 2014;21:167-74 pubmed publisher
  27. Zhou Y, Caron P, Legube G, Paull T. Quantitation of DNA double-strand break resection intermediates in human cells. Nucleic Acids Res. 2014;42:e19 pubmed publisher
  28. Mund A, Schubert T, Staege H, Kinkley S, Reumann K, Kriegs M, et al. SPOC1 modulates DNA repair by regulating key determinants of chromatin compaction and DNA damage response. Nucleic Acids Res. 2012;40:11363-79 pubmed publisher