This is a Validated Antibody Database (VAD) review about human RB1CC1, based on 16 published articles (read how Labome selects the articles), using RB1CC1 antibody in all methods. It is aimed to help Labome visitors find the most suited RB1CC1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
RB1CC1 synonym: ATG17; CC1; FIP200; PPP1R131; RB1-inducible coiled-coil protein 1; 200 kDa FAK family kinase-interacting protein; FAK family kinase-interacting protein of 200 kDa; phosphatase 1, regulatory subunit 131

Knockout validation
Proteintech Group
rabbit polyclonal
  • western blot knockout validation; mouse; loading ...; fig 1a
Proteintech Group RB1CC1 antibody (ProteinTech, -) was used in western blot knockout validation on mouse samples (fig 1a). FASEB J (2015) ncbi
Proteintech Group
rabbit polyclonal
  • western blot knockout validation; mouse
Proteintech Group RB1CC1 antibody (proteintech, 17250-1-AP) was used in western blot knockout validation on mouse samples . Endocrinology (2012) ncbi
Cell Signaling Technology
rabbit monoclonal (D10D11)
  • western blot knockout validation; human; 1:1000; loading ...; fig 1e
Cell Signaling Technology RB1CC1 antibody (Cell Signaling, 12436) was used in western blot knockout validation on human samples at 1:1000 (fig 1e). Cell Rep (2017) ncbi
Proteintech Group
rabbit polyclonal
  • western blot; human; loading ...; fig 9f
Proteintech Group RB1CC1 antibody (Proteintech, 17250?C1-AP) was used in western blot on human samples (fig 9f). elife (2017) ncbi
rabbit polyclonal
  • immunocytochemistry; human; fig s6a
In order to investigate how ataxia-telangiectasia mutated signaling regulates pexophagy, Proteintech Group RB1CC1 antibody (Proteintech;, 10043-2-AP) was used in immunocytochemistry on human samples (fig s6a). Nat Cell Biol (2015) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 1e
Proteintech Group RB1CC1 antibody (ProteinTech, -) was used in western blot on human samples at 1:1000 (fig 1e). Sci Rep (2015) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 7a
Proteintech Group RB1CC1 antibody (Proteintech Group, -) was used in western blot on mouse samples at 1:1000 (fig 7a). Biomed Res Int (2015) ncbi
rabbit polyclonal
  • western blot knockout validation; mouse; loading ...; fig 1a
Proteintech Group RB1CC1 antibody (ProteinTech, -) was used in western blot knockout validation on mouse samples (fig 1a). FASEB J (2015) ncbi
rabbit polyclonal
  • immunocytochemistry; human; 1:400
In order to identify and characterize the Nrbf2-Beclin 1 interaction, Proteintech Group RB1CC1 antibody (ProteinTech, 10043-2-AP) was used in immunocytochemistry on human samples at 1:400. J Biol Chem (2014) ncbi
rabbit polyclonal
  • immunocytochemistry; human; 1:70
Proteintech Group RB1CC1 antibody (Proteintech, 17250-1-AP) was used in immunocytochemistry on human samples at 1:70. Curr Protoc Cytom (2014) ncbi
rabbit polyclonal
  • western blot; mouse
In order to study the impact of autophagy on bone homeostasis, Proteintech Group RB1CC1 antibody (proteintech, 17250-1-AP) was used in western blot on mouse samples . J Bone Miner Res (2013) ncbi
rabbit polyclonal
  • western blot knockout validation; mouse
Proteintech Group RB1CC1 antibody (proteintech, 17250-1-AP) was used in western blot knockout validation on mouse samples . Endocrinology (2012) ncbi
Bethyl
rabbit polyclonal
  • western blot; human; fig 1b
Bethyl RB1CC1 antibody (Bethyl Laboratories, A301-536A) was used in western blot on human samples (fig 1b). Autophagy (2015) ncbi
rabbit polyclonal
  • western blot; human; fig 2c
Bethyl RB1CC1 antibody (Bethyl Laboratories, A301-574A) was used in western blot on human samples (fig 2c). Autophagy (2015) ncbi
Cell Signaling Technology
rabbit monoclonal (D10D11)
  • western blot; mouse; 1:1000; fig 8d
Cell Signaling Technology RB1CC1 antibody (Cell Signaling, 12436) was used in western blot on mouse samples at 1:1000 (fig 8d). Nat Commun (2018) ncbi
rabbit monoclonal (D10D11)
  • western blot knockout validation; human; 1:1000; loading ...; fig 1e
Cell Signaling Technology RB1CC1 antibody (Cell Signaling, 12436) was used in western blot knockout validation on human samples at 1:1000 (fig 1e). Cell Rep (2017) ncbi
rabbit monoclonal (D10D11)
  • immunocytochemistry; human; 1:100; loading ...; fig 6c
  • western blot; human; 1:1000; loading ...; fig 6d
In order to research the roles of WIPI3 and WIPI4 in autophagy, Cell Signaling Technology RB1CC1 antibody (Cell Signaling, 12436) was used in immunocytochemistry on human samples at 1:100 (fig 6c) and in western blot on human samples at 1:1000 (fig 6d). Nat Commun (2017) ncbi
rabbit monoclonal (D10D11)
  • western blot; human; loading ...; fig 2b
Cell Signaling Technology RB1CC1 antibody (Cell Signaling, D10D11) was used in western blot on human samples (fig 2b). J Cell Biol (2016) ncbi
rabbit monoclonal (D10D11)
  • western blot; human; fig 4
In order to analyze prevention of BECN2-mediated drug tolerance to cannabioids by autophagy activation by novel inducers, Cell Signaling Technology RB1CC1 antibody (Cell Signaling, 12436) was used in western blot on human samples (fig 4). Autophagy (2016) ncbi
Articles Reviewed
  1. Zhu L, Xie X, Zhang L, Wang H, Jie Z, Zhou X, et al. TBK-binding protein 1 regulates IL-15-induced autophagy and NKT cell survival. Nat Commun. 2018;9:2812 pubmed publisher
  2. Goodwin J, Dowdle W, Dejesus R, Wang Z, Bergman P, Kobylarz M, et al. Autophagy-Independent Lysosomal Targeting Regulated by ULK1/2-FIP200 and ATG9. Cell Rep. 2017;20:2341-2356 pubmed publisher
  3. Bakula D, Müller A, Zuleger T, Takacs Z, Franz Wachtel M, Thost A, et al. WIPI3 and WIPI4 β-propellers are scaffolds for LKB1-AMPK-TSC signalling circuits in the control of autophagy. Nat Commun. 2017;8:15637 pubmed publisher
  4. Jung J, Nayak A, Schaeffer V, Starzetz T, Kirsch A, Muller S, et al. Multiplex image-based autophagy RNAi screening identifies SMCR8 as ULK1 kinase activity and gene expression regulator. elife. 2017;6: pubmed publisher
  5. Yamashita S, Jin X, Furukawa K, Hamasaki M, Nezu A, Otera H, et al. Mitochondrial division occurs concurrently with autophagosome formation but independently of Drp1 during mitophagy. J Cell Biol. 2016;215:649-665 pubmed
  6. Kuramoto K, Wang N, Fan Y, Zhang W, Schoenen F, Frankowski K, et al. Autophagy activation by novel inducers prevents BECN2-mediated drug tolerance to cannabinoids. Autophagy. 2016;12:1460-71 pubmed publisher
  7. Zhang J, Tripathi D, Jing J, Alexander A, Kim J, Powell R, et al. ATM functions at the peroxisome to induce pexophagy in response to ROS. Nat Cell Biol. 2015;17:1259-1269 pubmed publisher
  8. Hieke N, Löffler A, Kaizuka T, Berleth N, Böhler P, Drießen S, et al. Expression of a ULK1/2 binding-deficient ATG13 variant can partially restore autophagic activity in ATG13-deficient cells. Autophagy. 2015;11:1471-83 pubmed publisher
  9. Drießen S, Berleth N, Friesen O, Löffler A, Böhler P, Hieke N, et al. Deubiquitinase inhibition by WP1130 leads to ULK1 aggregation and blockade of autophagy. Autophagy. 2015;11:1458-70 pubmed publisher
  10. Chen Y, Peng Y, Hu M, Huang J, Chien Y, Wu J, et al. The Cullin 4A/B-DDB1-Cereblon E3 Ubiquitin Ligase Complex Mediates the Degradation of CLC-1 Chloride Channels. Sci Rep. 2015;5:10667 pubmed publisher
  11. Ulanova A, Gritsyna Y, Vikhlyantsev I, Salmov N, Bobylev A, Abdusalamova Z, et al. Isoform composition and gene expression of thick and thin filament proteins in striated muscles of mice after 30-day space flight. Biomed Res Int. 2015;2015:104735 pubmed publisher
  12. Morrison A, Chen L, Wang J, Zhang M, Yang H, Ma Y, et al. Sestrin2 promotes LKB1-mediated AMPK activation in the ischemic heart. FASEB J. 2015;29:408-17 pubmed publisher
  13. Zhong Y, Morris D, Jin L, Patel M, Karunakaran S, Fu Y, et al. Nrbf2 protein suppresses autophagy by modulating Atg14L protein-containing Beclin 1-Vps34 complex architecture and reducing intracellular phosphatidylinositol-3 phosphate levels. J Biol Chem. 2014;289:26021-37 pubmed publisher
  14. Karanasios E, Stapleton E, Manifava M, Ktistakis N. Imaging autophagy. Curr Protoc Cytom. 2014;69:12.34.1-12.34.16 pubmed publisher
  15. Liu F, Fang F, Yuan H, Yang D, Chen Y, Williams L, et al. Suppression of autophagy by FIP200 deletion leads to osteopenia in mice through the inhibition of osteoblast terminal differentiation. J Bone Miner Res. 2013;28:2414-30 pubmed publisher
  16. Lejonklou M, Barbu A, Stalberg P, Skogseid B. Accelerated proliferation and differential global gene expression in pancreatic islets of five-week-old heterozygous Men1 mice: Men1 is a haploinsufficient suppressor. Endocrinology. 2012;153:2588-98 pubmed publisher