This is a Validated Antibody Database (VAD) review about human RAPGEF2, based on 3 published articles (read how Labome selects the articles), using RAPGEF2 antibody in all methods. It is aimed to help Labome visitors find the most suited RAPGEF2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
RAPGEF2 synonym: CNrasGEF; NRAPGEP; PDZ-GEF1; PDZGEF1; RA-GEF; RA-GEF-1; Rap-GEP; nRap GEP; rap guanine nucleotide exchange factor 2; PDZ domain containing guanine nucleotide exchange factor (GEF) 1; PDZ domain-containing guanine nucleotide exchange factor 1; RA(Ras/Rap1A-associating)-GEF; Rap guanine nucleotide exchange factor (GEF) 2; cyclic nucleotide ras GEF; neural RAP guanine nucleotide exchange protein; ras/Rap1-associating GEF-1

Bethyl
rabbit polyclonal
  • western blot; human; fig 2a
In order to use the parallel adapter capture proteomics approach to identify substrates of betaTrCP2/FBXW11, Bethyl RAPGEF2 antibody (Bethyl, A301-966A) was used in western blot on human samples (fig 2a). Mol Cell Biol (2015) ncbi
rabbit polyclonal
  • western blot; human; fig 7a
  • immunohistochemistry - frozen section; mouse; 1:1000; fig 1b
  • western blot; mouse; fig 1a
In order to study the initiation and regulation of radial migration, Bethyl RAPGEF2 antibody (Bethyl, A301-966A) was used in western blot on human samples (fig 7a), in immunohistochemistry - frozen section on mouse samples at 1:1000 (fig 1b) and in western blot on mouse samples (fig 1a). Nat Commun (2014) ncbi
Abnova
mouse monoclonal (1E8)
  • western blot; mouse; fig 5
In order to study the dysregulation of Rap2 activity due to PSD-Zip70 deficiency that causes prefrontal hypofunction associated with glutamatergic synapse maturation defects, Abnova RAPGEF2 antibody (Abnova, H00009693) was used in western blot on mouse samples (fig 5). J Neurosci (2015) ncbi
Articles Reviewed
  1. Mayanagi T, Yasuda H, Sobue K. PSD-Zip70 Deficiency Causes Prefrontal Hypofunction Associated with Glutamatergic Synapse Maturation Defects by Dysregulation of Rap2 Activity. J Neurosci. 2015;35:14327-40 pubmed publisher
  2. Kim T, Siesser P, Rossman K, Goldfarb D, Mackinnon K, Yan F, et al. Substrate trapping proteomics reveals targets of the βTrCP2/FBXW11 ubiquitin ligase. Mol Cell Biol. 2015;35:167-81 pubmed publisher
  3. Ye T, Ip J, Fu A, Ip N. Cdk5-mediated phosphorylation of RapGEF2 controls neuronal migration in the developing cerebral cortex. Nat Commun. 2014;5:4826 pubmed publisher