This is a Validated Antibody Database (VAD) review about human RAB7A, based on 101 published articles (read how Labome selects the articles), using RAB7A antibody in all methods. It is aimed to help Labome visitors find the most suited RAB7A antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
RAB7A synonym: CMT2B; PRO2706; RAB7

Knockout validation
Abcam
domestic rabbit monoclonal (EPR7589)
  • immunocytochemistry knockout validation; human; 1:100; loading ...; fig 1b
  • western blot; human; 1:1000; loading ...; fig s4d
Abcam RAB7A antibody (Abcam, EPR7589) was used in immunocytochemistry knockout validation on human samples at 1:100 (fig 1b) and in western blot on human samples at 1:1000 (fig s4d). EMBO J (2018) ncbi
Abcam
domestic rabbit monoclonal (EPR7589)
  • immunocytochemistry knockout validation; mouse; fig 2D
  • western blot knockout validation; mouse; fig 2C
In order to report a B cell-intrinsic role for Rab7, Abcam RAB7A antibody (Abcam, ab137029) was used in immunocytochemistry knockout validation on mouse samples (fig 2D) and in western blot knockout validation on mouse samples (fig 2C). J Immunol (2015) ncbi
Novus Biologicals
domestic rabbit polyclonal
  • western blot knockout validation; human; loading ...; fig s3a, s3c
Novus Biologicals RAB7A antibody (NovusBio, NBP1-87174) was used in western blot knockout validation on human samples (fig s3a, s3c). Cell (2021) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D95F2)
  • immunocytochemistry knockout validation; mouse; fig 1
  • western blot knockout validation; mouse; fig 1
  • flow cytometry; mouse; fig 1
Cell Signaling Technology RAB7A antibody (Cell Signaling, 9367) was used in immunocytochemistry knockout validation on mouse samples (fig 1), in western blot knockout validation on mouse samples (fig 1) and in flow cytometry on mouse samples (fig 1). Autophagy (2013) ncbi
Abcam
domestic rabbit monoclonal (EPR7589)
  • western blot; mouse; 1:1000; loading ...; fig 6g
Abcam RAB7A antibody (Abcam, ab137029) was used in western blot on mouse samples at 1:1000 (fig 6g). EBioMedicine (2022) ncbi
mouse monoclonal (Rab7-117)
  • immunohistochemistry; pigs ; 1:200; loading ...; fig 1d
Abcam RAB7A antibody (Abcam, ab50533) was used in immunohistochemistry on pigs samples at 1:200 (fig 1d). Vet Res Commun (2022) ncbi
domestic rabbit monoclonal (EPR7589)
  • immunohistochemistry; mouse; loading ...; fig 6a
Abcam RAB7A antibody (Abcam, ab137029) was used in immunohistochemistry on mouse samples (fig 6a). Int J Mol Sci (2020) ncbi
domestic rabbit monoclonal (EPR7589)
  • immunohistochemistry - free floating section; mouse; loading ...; fig 8c
  • western blot; mouse; 1:1000; loading ...; fig 8a
Abcam RAB7A antibody (Abcam, ab137029) was used in immunohistochemistry - free floating section on mouse samples (fig 8c) and in western blot on mouse samples at 1:1000 (fig 8a). J Neuroinflammation (2020) ncbi
mouse monoclonal (Rab7-117)
  • western blot; human; 1:1000; loading ...; fig 1d
Abcam RAB7A antibody (Abcam, ab50533) was used in western blot on human samples at 1:1000 (fig 1d). elife (2019) ncbi
mouse monoclonal (Rab7-117)
  • immunocytochemistry; human; loading ...; fig 4m
Abcam RAB7A antibody (Abcam, Rab7-117) was used in immunocytochemistry on human samples (fig 4m). Front Immunol (2018) ncbi
domestic rabbit monoclonal (EPR7589)
  • ELISA; mouse; 1:1000; loading ...; fig 3c
Abcam RAB7A antibody (Abcam, ab137029) was used in ELISA on mouse samples at 1:1000 (fig 3c). Nat Cell Biol (2019) ncbi
mouse monoclonal (Rab7-117)
  • immunocytochemistry; mouse; loading ...; fig s10e
Abcam RAB7A antibody (Abcam, ab50533) was used in immunocytochemistry on mouse samples (fig s10e). Science (2018) ncbi
mouse monoclonal (Rab7-117)
  • immunohistochemistry; mouse; 1:2000; loading ...; fig s5
Abcam RAB7A antibody (Abcam, ab50533) was used in immunohistochemistry on mouse samples at 1:2000 (fig s5). J Clin Invest (2018) ncbi
domestic rabbit monoclonal (EPR7589)
  • immunocytochemistry knockout validation; human; 1:100; loading ...; fig 1b
  • western blot; human; 1:1000; loading ...; fig s4d
Abcam RAB7A antibody (Abcam, EPR7589) was used in immunocytochemistry knockout validation on human samples at 1:100 (fig 1b) and in western blot on human samples at 1:1000 (fig s4d). EMBO J (2018) ncbi
mouse monoclonal (Rab7-117)
  • western blot; rat; 1:500; loading ...; fig 5e
Abcam RAB7A antibody (Abcam, 50533) was used in western blot on rat samples at 1:500 (fig 5e). J Cell Biol (2017) ncbi
mouse monoclonal (Rab7-117)
  • immunocytochemistry; pigs ; fig 3d
Abcam RAB7A antibody (Abcam, ab50533) was used in immunocytochemistry on pigs samples (fig 3d). Biochim Biophys Acta Mol Cell Biol Lipids (2017) ncbi
mouse monoclonal (Rab7-117)
  • western blot; mouse; fig 8
In order to study the role of CD146 in the formation and retention of macrophage foam cells, Abcam RAB7A antibody (Abcam, ab50533) was used in western blot on mouse samples (fig 8). Cell Res (2017) ncbi
domestic rabbit monoclonal (EPR7588(B))
  • immunohistochemistry - frozen section; rat; fig 5
Abcam RAB7A antibody (Abcam, ab126712) was used in immunohistochemistry - frozen section on rat samples (fig 5). PLoS ONE (2016) ncbi
mouse monoclonal (Rab7-117)
  • immunocytochemistry; mouse; loading ...; fig 3g
Abcam RAB7A antibody (Abcam, ab50533) was used in immunocytochemistry on mouse samples (fig 3g). Oncotarget (2016) ncbi
mouse monoclonal (Rab7-117)
  • immunohistochemistry; human; 1:100; loading ...; fig 4e
Abcam RAB7A antibody (Abcam, ab50533) was used in immunohistochemistry on human samples at 1:100 (fig 4e). J Immunol (2016) ncbi
domestic rabbit monoclonal (EPR7589)
  • western blot; mouse; fig 1
Abcam RAB7A antibody (Abcam, Ab137029) was used in western blot on mouse samples (fig 1). EMBO J (2016) ncbi
mouse monoclonal (Rab7-117)
  • western blot; mouse; fig 1
In order to mediate direct uptake of RNA by lysosomes by lysosomal putative RNA transporter SIDT2, Abcam RAB7A antibody (Abcam, ab50533) was used in western blot on mouse samples (fig 1). Autophagy (2016) ncbi
mouse monoclonal (Rab7-117)
  • immunocytochemistry; human; 1:1000; fig 4
In order to study how importation of copper into cells is regulated, Abcam RAB7A antibody (Abcam, ab50533) was used in immunocytochemistry on human samples at 1:1000 (fig 4). J Cell Sci (2016) ncbi
mouse monoclonal (Rab7-117)
  • immunocytochemistry; human; loading ...; fig 4
In order to research the involvement of miRNA in cholesterol homeostasis, Abcam RAB7A antibody (Abcam, 50533) was used in immunocytochemistry on human samples (fig 4). Arterioscler Thromb Vasc Biol (2016) ncbi
mouse monoclonal (Rab7-117)
  • immunocytochemistry; mouse; 1:200-1:500; fig 7
Abcam RAB7A antibody (Abcam, ab50533) was used in immunocytochemistry on mouse samples at 1:200-1:500 (fig 7). PLoS Genet (2015) ncbi
mouse monoclonal (Rab7-117)
  • western blot; mouse
In order to assess the effects of an autophagy inducer on col6a1 knock out mice, Abcam RAB7A antibody (Abcam, ab50533) was used in western blot on mouse samples . Autophagy (2015) ncbi
domestic rabbit monoclonal (EPR7589)
  • immunocytochemistry; human; 1:300; fig 2
  • western blot; human; 1:1000; fig 4
Abcam RAB7A antibody (Abcam, ab137029) was used in immunocytochemistry on human samples at 1:300 (fig 2) and in western blot on human samples at 1:1000 (fig 4). Nat Commun (2015) ncbi
mouse monoclonal (Rab7-117)
  • immunohistochemistry - paraffin section; mouse
Abcam RAB7A antibody (Abcam, Rab7-117) was used in immunohistochemistry - paraffin section on mouse samples . Front Cell Neurosci (2015) ncbi
domestic rabbit monoclonal (EPR7589)
  • immunocytochemistry knockout validation; mouse; fig 2D
  • western blot knockout validation; mouse; fig 2C
In order to report a B cell-intrinsic role for Rab7, Abcam RAB7A antibody (Abcam, ab137029) was used in immunocytochemistry knockout validation on mouse samples (fig 2D) and in western blot knockout validation on mouse samples (fig 2C). J Immunol (2015) ncbi
mouse monoclonal (Rab7-117)
  • immunoprecipitation; rat
  • western blot; rat
  • immunoprecipitation; mouse
  • western blot; mouse
Abcam RAB7A antibody (Abcam, ab50533) was used in immunoprecipitation on rat samples , in western blot on rat samples , in immunoprecipitation on mouse samples and in western blot on mouse samples . J Neurosci (2015) ncbi
mouse monoclonal (Rab7-117)
  • immunocytochemistry; mouse; 1:50; fig 2a
  • western blot; mouse; 1:500; fig 2b
  • immunohistochemistry - paraffin section; human; 1:50; fig 4a
In order to show that C9ORF72 regulates endosomal trafficking, Abcam RAB7A antibody (Abcam, ab50533) was used in immunocytochemistry on mouse samples at 1:50 (fig 2a), in western blot on mouse samples at 1:500 (fig 2b) and in immunohistochemistry - paraffin section on human samples at 1:50 (fig 4a). Hum Mol Genet (2014) ncbi
mouse monoclonal (Rab7-117)
  • western blot; human; fig 3
In order to study the interaction of the TIP47 lipid droplet-binding protein with HCV NS5A and the role of this interaction in the regulation of viral RNA replication, Abcam RAB7A antibody (Abcam, ab50533) was used in western blot on human samples (fig 3). PLoS Pathog (2013) ncbi
mouse monoclonal (Rab7-117)
  • immunocytochemistry; human
Abcam RAB7A antibody (Abcam, ab50533) was used in immunocytochemistry on human samples . FASEB J (2013) ncbi
mouse monoclonal (Rab7-117)
  • immunocytochemistry; dogs
  • western blot; dogs
Abcam RAB7A antibody (Abcam, ab50533) was used in immunocytochemistry on dogs samples and in western blot on dogs samples . J Biol Chem (2012) ncbi
Santa Cruz Biotechnology
mouse monoclonal (B-3)
  • immunocytochemistry; mouse; loading ...; fig s3a
Santa Cruz Biotechnology RAB7A antibody (Santa Cruz, sc-376362) was used in immunocytochemistry on mouse samples (fig s3a). Cell Rep (2021) ncbi
mouse monoclonal (B-3)
  • western blot; mouse; 1:800; fig 5i
Santa Cruz Biotechnology RAB7A antibody (Santa Cruz Biotechnology, sc-376362) was used in western blot on mouse samples at 1:800 (fig 5i). BMC Biol (2021) ncbi
mouse monoclonal (D-4)
  • immunocytochemistry; human; loading ...; fig 2f
Santa Cruz Biotechnology RAB7A antibody (Santa Cruz Biotech, SC-271608) was used in immunocytochemistry on human samples (fig 2f). Sci Transl Med (2020) ncbi
mouse monoclonal (B-3)
  • immunocytochemistry; human; loading ...; fig 4f
  • western blot; human; loading ...; fig 5f
In order to investigate Rab7 and Arl8b crosstalk, Santa Cruz Biotechnology RAB7A antibody (Santa Cruz, sc-376362) was used in immunocytochemistry on human samples (fig 4f) and in western blot on human samples (fig 5f). J Cell Biol (2017) ncbi
mouse monoclonal (B-3)
  • western blot; human; 1:800; fig 7f
Santa Cruz Biotechnology RAB7A antibody (SantaCruz, sc-376362) was used in western blot on human samples at 1:800 (fig 7f). EMBO Mol Med (2017) ncbi
mouse monoclonal (B-3)
  • blocking or activating experiments; mouse; fig 3
  • immunocytochemistry; mouse; fig 2
Santa Cruz Biotechnology RAB7A antibody (Santa Cruz Biotechnology, sc-376362) was used in blocking or activating experiments on mouse samples (fig 3) and in immunocytochemistry on mouse samples (fig 2). Sci Rep (2016) ncbi
mouse monoclonal (B-3)
  • immunocytochemistry; human; 1:50; fig 6
In order to research the modulation of beta-amyloidogenic processing of APP by affecting the sorting and accumulation of BACE1 by SEPT8, Santa Cruz Biotechnology RAB7A antibody (Santa Cruz, sc-376362) was used in immunocytochemistry on human samples at 1:50 (fig 6). J Cell Sci (2016) ncbi
mouse monoclonal (D-4)
  • western blot; human; 1:1000; loading ...; fig 6
Santa Cruz Biotechnology RAB7A antibody (Santa Cruz, sc-271608) was used in western blot on human samples at 1:1000 (fig 6). Cell Death Dis (2014) ncbi
Novus Biologicals
domestic rabbit polyclonal
  • western blot knockout validation; human; loading ...; fig s3a, s3c
Novus Biologicals RAB7A antibody (NovusBio, NBP1-87174) was used in western blot knockout validation on human samples (fig s3a, s3c). Cell (2021) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D95F2)
  • western blot; mouse; loading ...; fig e4b
Cell Signaling Technology RAB7A antibody (Cell Signaling, 9367) was used in western blot on mouse samples (fig e4b). EMBO J (2022) ncbi
domestic rabbit monoclonal (D95F2)
  • immunocytochemistry; human; 1:100; loading ...; fig 2d
Cell Signaling Technology RAB7A antibody (Cell Signaling, D95F2) was used in immunocytochemistry on human samples at 1:100 (fig 2d). Nat Commun (2021) ncbi
domestic rabbit monoclonal (D95F2)
  • immunoprecipitation; human; 1:100; loading ...; fig 6a
  • immunocytochemistry; human; 1:100; loading ...; fig 6b
  • western blot; human; 1:1000; loading ...; fig 7b
Cell Signaling Technology RAB7A antibody (CST, 9367) was used in immunoprecipitation on human samples at 1:100 (fig 6a), in immunocytochemistry on human samples at 1:100 (fig 6b) and in western blot on human samples at 1:1000 (fig 7b). Clin Transl Med (2021) ncbi
domestic rabbit monoclonal (D95F2)
  • western blot; human; 1:1000; loading ...; fig 3h
Cell Signaling Technology RAB7A antibody (CST, 9367) was used in western blot on human samples at 1:1000 (fig 3h). Acta Neuropathol (2021) ncbi
domestic rabbit monoclonal (D95F2)
  • western blot; mouse; 1:1000; loading ...; fig 6b
Cell Signaling Technology RAB7A antibody (CST, 9367) was used in western blot on mouse samples at 1:1000 (fig 6b). Sci Rep (2020) ncbi
domestic rabbit monoclonal (D95F2)
  • immunocytochemistry; human; loading ...; fig 1
Cell Signaling Technology RAB7A antibody (CST, 9367) was used in immunocytochemistry on human samples (fig 1). J Cell Mol Med (2020) ncbi
domestic rabbit monoclonal (D95F2)
  • immunocytochemistry; human; 1:60; loading ...; fig 7s1b
Cell Signaling Technology RAB7A antibody (CST, 9367) was used in immunocytochemistry on human samples at 1:60 (fig 7s1b). elife (2019) ncbi
domestic rabbit monoclonal (D95F2)
  • immunocytochemistry; human; 1:100; loading ...; fig e4a
Cell Signaling Technology RAB7A antibody (Cell Signaling, 9367S) was used in immunocytochemistry on human samples at 1:100 (fig e4a). Nature (2019) ncbi
domestic rabbit monoclonal (D95F2)
  • western blot; mouse; 1:1000; loading ...; fig 5c
Cell Signaling Technology RAB7A antibody (CST, 9367) was used in western blot on mouse samples at 1:1000 (fig 5c). Science (2019) ncbi
domestic rabbit monoclonal (D95F2)
  • western blot; human; loading ...; fig 2d
Cell Signaling Technology RAB7A antibody (Cell Signaling, 9367) was used in western blot on human samples (fig 2d). Biol Open (2019) ncbi
domestic rabbit monoclonal (D95F2)
  • immunocytochemistry; mouse; loading ...; fig 9e
Cell Signaling Technology RAB7A antibody (Cell Signaling, D95F2) was used in immunocytochemistry on mouse samples (fig 9e). J Exp Med (2019) ncbi
domestic rabbit monoclonal (D95F2)
  • immunocytochemistry; human; 1:250; loading ...; fig s2
Cell Signaling Technology RAB7A antibody (Cell Signaling, 9367S) was used in immunocytochemistry on human samples at 1:250 (fig s2). J Cell Sci (2019) ncbi
domestic rabbit monoclonal (D95F2)
  • western blot; mouse; loading ...; fig 3a
Cell Signaling Technology RAB7A antibody (Cell Signaling, 9367) was used in western blot on mouse samples (fig 3a). EMBO J (2019) ncbi
domestic rabbit monoclonal (D95F2)
  • western blot; human; loading ...; fig 2e
Cell Signaling Technology RAB7A antibody (Cell Signaling, 9367S) was used in western blot on human samples (fig 2e). Cell (2019) ncbi
domestic rabbit monoclonal (D95F2)
  • immunocytochemistry; human; 1:100; loading ...; fig 5a
  • western blot; human; loading ...; fig 6f
Cell Signaling Technology RAB7A antibody (Cell Signaling, 9367s) was used in immunocytochemistry on human samples at 1:100 (fig 5a) and in western blot on human samples (fig 6f). Nat Commun (2019) ncbi
domestic rabbit monoclonal (D95F2)
  • immunocytochemistry; fruit fly ; 1:5; loading ...; fig 2h
  • immunocytochemistry; mouse; 1:200; loading ...; fig 6c
Cell Signaling Technology RAB7A antibody (Cell Signaling, 9367) was used in immunocytochemistry on fruit fly samples at 1:5 (fig 2h) and in immunocytochemistry on mouse samples at 1:200 (fig 6c). elife (2019) ncbi
domestic rabbit monoclonal (D95F2)
  • immunocytochemistry; mouse; 1:100; loading ...; fig 1d
Cell Signaling Technology RAB7A antibody (Cell Signaling, 9367) was used in immunocytochemistry on mouse samples at 1:100 (fig 1d). J Cell Biol (2019) ncbi
domestic rabbit monoclonal (D95F2)
  • immunocytochemistry; mouse; 1:100; loading ...; fig 6e
Cell Signaling Technology RAB7A antibody (Cell Signaling, D95F2) was used in immunocytochemistry on mouse samples at 1:100 (fig 6e). J Cell Biol (2019) ncbi
domestic rabbit monoclonal (D95F2)
  • proximity ligation assay; human; 1:100; loading ...; fig 5b, 5f
Cell Signaling Technology RAB7A antibody (Cell Signaling, 9367) was used in proximity ligation assay on human samples at 1:100 (fig 5b, 5f). Cell Rep (2018) ncbi
domestic rabbit monoclonal (D95F2)
  • immunocytochemistry; mouse; loading ...; fig s3g
Cell Signaling Technology RAB7A antibody (Cell Signaling, 9367S) was used in immunocytochemistry on mouse samples (fig s3g). Cell (2018) ncbi
domestic rabbit monoclonal (D95F2)
  • western blot; mouse; loading ...; fig 5a
Cell Signaling Technology RAB7A antibody (Cell Signaling Technology, 9367) was used in western blot on mouse samples (fig 5a). EMBO J (2018) ncbi
domestic rabbit monoclonal (D95F2)
  • western blot; mouse; fig 7a
Cell Signaling Technology RAB7A antibody (Cell Signaling, 9367) was used in western blot on mouse samples (fig 7a). J Biol Chem (2018) ncbi
domestic rabbit monoclonal (D95F2)
  • western blot; mouse; loading ...; fig 6b
Cell Signaling Technology RAB7A antibody (Cell Signaling, 9367) was used in western blot on mouse samples (fig 6b). Proc Natl Acad Sci U S A (2017) ncbi
domestic rabbit monoclonal (D95F2)
  • immunocytochemistry; mouse; loading ...; fig s5b
Cell Signaling Technology RAB7A antibody (Cell Signaling, 9367) was used in immunocytochemistry on mouse samples (fig s5b). PLoS Genet (2017) ncbi
domestic rabbit monoclonal (D95F2)
  • immunocytochemistry; human; loading ...; fig s5
Cell Signaling Technology RAB7A antibody (cell signalling, D95F2) was used in immunocytochemistry on human samples (fig s5). PLoS Pathog (2017) ncbi
domestic rabbit monoclonal (D95F2)
  • immunoprecipitation; human; loading ...; fig 5g
  • immunocytochemistry; human; loading ...; fig 5k
  • western blot; human; loading ...; fig 5g
In order to investigate Rab7 and Arl8b crosstalk, Cell Signaling Technology RAB7A antibody (Cell Signaling, 9367) was used in immunoprecipitation on human samples (fig 5g), in immunocytochemistry on human samples (fig 5k) and in western blot on human samples (fig 5g). J Cell Biol (2017) ncbi
domestic rabbit monoclonal (D95F2)
  • immunocytochemistry; human; loading ...; fig s5e
Cell Signaling Technology RAB7A antibody (Cell Signaling, 9367) was used in immunocytochemistry on human samples (fig s5e). Nature (2017) ncbi
domestic rabbit monoclonal (D95F2)
  • western blot; mouse; 1:1000; loading ...; fig 7c
In order to elucidate a novel pathway for mitochondrial elimination, in which these organelles undergo Parkin-dependent sequestration into Rab5-positive early endosomes via the ESCRT machinery, Cell Signaling Technology RAB7A antibody (Cell Signaling, 9367) was used in western blot on mouse samples at 1:1000 (fig 7c). Nat Commun (2017) ncbi
domestic rabbit monoclonal (D95F2)
  • immunocytochemistry; human; loading ...; fig 4a
  • western blot; human; loading ...; fig 1c
In order to determine the role of SNAPIN in macrophages, Cell Signaling Technology RAB7A antibody (Cell Signaling, 9367) was used in immunocytochemistry on human samples (fig 4a) and in western blot on human samples (fig 1c). Autophagy (2017) ncbi
domestic rabbit monoclonal (D95F2)
  • western blot; mouse; 1:1000; loading ...; fig 6a
In order to observe that a single amino acid change within Rabep2 accounting for the difference in collateral extent and infarct volume between B6 and BC mice maps to Dce1, Cell Signaling Technology RAB7A antibody (cell signalling, 9367S) was used in western blot on mouse samples at 1:1000 (fig 6a). Stroke (2016) ncbi
domestic rabbit monoclonal (D95F2)
  • immunocytochemistry; mouse; 1:300; fig 3
  • western blot; mouse; 1:5000; fig 3
Cell Signaling Technology RAB7A antibody (Cell Signaling, 9367) was used in immunocytochemistry on mouse samples at 1:300 (fig 3) and in western blot on mouse samples at 1:5000 (fig 3). J Cell Sci (2016) ncbi
domestic rabbit monoclonal (D95F2)
  • immunocytochemistry; human; loading ...; fig 7a
  • western blot; human; loading ...; fig 7e
Cell Signaling Technology RAB7A antibody (cell signalling, 9367) was used in immunocytochemistry on human samples (fig 7a) and in western blot on human samples (fig 7e). PLoS Pathog (2016) ncbi
domestic rabbit monoclonal (D95F2)
  • immunocytochemistry; rat; loading ...; fig 5f
Cell Signaling Technology RAB7A antibody (Cell Signaling, D95F2) was used in immunocytochemistry on rat samples (fig 5f). Microbiologyopen (2017) ncbi
domestic rabbit monoclonal (D95F2)
  • western blot; dogs; loading ...; fig 11a
In order to elucidate the mechanism by which hypotonic stress reduces claudin-1 and -2 expression in renal tubular epithelial and canine kidney cells, Cell Signaling Technology RAB7A antibody (Cell signaling, 9367) was used in western blot on dogs samples (fig 11a). J Biol Chem (2016) ncbi
domestic rabbit monoclonal (D95F2)
  • immunocytochemistry; mouse; 1:100; fig 1s3
In order to report the mechanism by which thrombospondin-4 regulates skeletal muscle integrity, Cell Signaling Technology RAB7A antibody (Cell Signaling, 9367) was used in immunocytochemistry on mouse samples at 1:100 (fig 1s3). elife (2016) ncbi
domestic rabbit monoclonal (D95F2)
  • immunocytochemistry; mouse; loading ...; fig s8e
In order to show that LAMP-2 is essential for STX17 expression and for fusion of autophagasomes with lysosomes, Cell Signaling Technology RAB7A antibody (Cell Signaling, 9367) was used in immunocytochemistry on mouse samples (fig s8e). Biol Open (2016) ncbi
domestic rabbit monoclonal (D95F2)
  • immunocytochemistry; mouse; 1:100; fig 1
In order to study a phosphoinositide-based mechanism that Arf6 uses to control retromer traffic and intracellular cholesterol distribution, Cell Signaling Technology RAB7A antibody (Cell signaling, 9367) was used in immunocytochemistry on mouse samples at 1:100 (fig 1). Nat Commun (2016) ncbi
domestic rabbit monoclonal (D95F2)
  • immunocytochemistry; human; 1:100; loading ...; fig s1c
Cell Signaling Technology RAB7A antibody (Cell Signaling, D95F2) was used in immunocytochemistry on human samples at 1:100 (fig s1c). Nat Commun (2016) ncbi
domestic rabbit monoclonal (D95F2)
  • immunocytochemistry; human; fig 4
In order to analyze control of MT1-MMP endocytic and E-cadherin polarized golgi trafficking to promote invasive breast cancer programs by RAB2A, Cell Signaling Technology RAB7A antibody (Cell signaling, 9367) was used in immunocytochemistry on human samples (fig 4). EMBO Rep (2016) ncbi
domestic rabbit monoclonal (D95F2)
  • immunocytochemistry; human; loading ...; fig 2c
Cell Signaling Technology RAB7A antibody (Cell Signaling, D95F2) was used in immunocytochemistry on human samples (fig 2c). EMBO Rep (2016) ncbi
domestic rabbit monoclonal (D95F2)
  • immunocytochemistry; mouse; fig 2
Cell Signaling Technology RAB7A antibody (Cell Signaling Technology, 9367) was used in immunocytochemistry on mouse samples (fig 2). Mol Metab (2016) ncbi
domestic rabbit monoclonal (D95F2)
  • immunocytochemistry; mouse; loading ...; fig 2
  • immunocytochemistry; human; loading ...; fig 8a
Cell Signaling Technology RAB7A antibody (Cell Signaling Technology, D95F2) was used in immunocytochemistry on mouse samples (fig 2) and in immunocytochemistry on human samples (fig 8a). Sci Rep (2016) ncbi
domestic rabbit monoclonal (D95F2)
  • western blot; human; 1:1000; fig 2
Cell Signaling Technology RAB7A antibody (Cell signaling, 9367) was used in western blot on human samples at 1:1000 (fig 2). elife (2016) ncbi
domestic rabbit monoclonal (D95F2)
  • western blot; mouse; 1:500; loading ...; fig 5a
In order to use Kcne3 knockout mice to investigate atrial electrophysiology and the development of aldosterone-dependent atrial fibrillation, Cell Signaling Technology RAB7A antibody (Cell Signaling, 9367) was used in western blot on mouse samples at 1:500 (fig 5a). FASEB J (2016) ncbi
domestic rabbit monoclonal (D95F2)
  • immunocytochemistry; mouse; fig s5
Cell Signaling Technology RAB7A antibody (CST, 9367) was used in immunocytochemistry on mouse samples (fig s5). Acta Neuropathol (2016) ncbi
domestic rabbit monoclonal (D95F2)
  • immunocytochemistry; human; 1:50
In order to study the conversion of phosphatidylinositol 3-phosphate to phosphatidylinositol 4-phosphate at endosomes en route to the plasma membrane, Cell Signaling Technology RAB7A antibody (Cell Signalling, D95F2) was used in immunocytochemistry on human samples at 1:50. Nature (2016) ncbi
domestic rabbit monoclonal (D95F2)
  • western blot; mouse; 1:1000; loading ...; fig 6d
Cell Signaling Technology RAB7A antibody (Cell Signaling, 9367) was used in western blot on mouse samples at 1:1000 (fig 6d). Oncotarget (2016) ncbi
domestic rabbit monoclonal (D95F2)
  • western blot; mouse; fig 2
In order to investigate a mechanism of late endosomal maturation, Cell Signaling Technology RAB7A antibody (Cell Signaling Technology, D95F2) was used in western blot on mouse samples (fig 2). Mol Biol Cell (2016) ncbi
domestic rabbit monoclonal (D95F2)
  • immunocytochemistry; human; fig 2
Cell Signaling Technology RAB7A antibody (BD, 9367) was used in immunocytochemistry on human samples (fig 2). J Cell Biol (2015) ncbi
domestic rabbit monoclonal (D95F2)
  • western blot; rat; 1:1000
In order to investigate the role of p18, Rab4, Rab7, and Rab9 in vessel formation within the pulmonary vasculature, Cell Signaling Technology RAB7A antibody (Cell Signaling, 9367S) was used in western blot on rat samples at 1:1000. Am J Physiol Lung Cell Mol Physiol (2015) ncbi
domestic rabbit monoclonal (D95F2)
  • immunocytochemistry; human; 1:100; fig 7
  • western blot; human; 1:2000; fig 7
In order to determine the role of PICALM in Abeta transcytosis across the blood brain barrier, Cell Signaling Technology RAB7A antibody (Cell Signaling, 9367) was used in immunocytochemistry on human samples at 1:100 (fig 7) and in western blot on human samples at 1:2000 (fig 7). Nat Neurosci (2015) ncbi
domestic rabbit monoclonal (D95F2)
  • immunocytochemistry; mouse; fig 7
In order to study regulation of selective autophagic clearance of protein aggregates due to proteotoxic stress inducing phosphorylation of p62/SQSTM1 by ULK1, Cell Signaling Technology RAB7A antibody (Cell signaling, 9367) was used in immunocytochemistry on mouse samples (fig 7). PLoS Genet (2015) ncbi
domestic rabbit monoclonal (D95F2)
  • immunocytochemistry; mouse; 1:50; fig s7a
In order to explore a macrophage TLR9-BTK-calcineurin-NFAT signaling pathway involved in impair fungal immunity, Cell Signaling Technology RAB7A antibody (Cell signaling, 9367) was used in immunocytochemistry on mouse samples at 1:50 (fig s7a). EMBO Mol Med (2015) ncbi
domestic rabbit monoclonal (D95F2)
  • western blot; mouse; fig 5b
In order to study the effect of bisecting N-acetylglucosamine on beta-site amyloid precursor protein cleaving enzyme-1 (BACE1) activity, Cell Signaling Technology RAB7A antibody (Cell Signaling Technology, 9367) was used in western blot on mouse samples (fig 5b). EMBO Mol Med (2015) ncbi
domestic rabbit monoclonal (D95F2)
  • immunocytochemistry; human; 1:100
Cell Signaling Technology RAB7A antibody (Cell Signaling, D95F2) was used in immunocytochemistry on human samples at 1:100. J Clin Invest (2015) ncbi
domestic rabbit monoclonal (D95F2)
  • western blot; human; fig 4
In order to assess adeno-associated virus transduction and its requirement for syntaxin 5-dependent retrograde transport to the trans-Golgi network, Cell Signaling Technology RAB7A antibody (Cell Signaling Technologies, D95F2) was used in western blot on human samples (fig 4). J Virol (2015) ncbi
domestic rabbit monoclonal (D95F2)
  • immunocytochemistry; human
Cell Signaling Technology RAB7A antibody (Cell Signaling Technology, D95F2) was used in immunocytochemistry on human samples . J Cell Sci (2014) ncbi
domestic rabbit monoclonal (D95F2)
  • immunocytochemistry; mouse
Cell Signaling Technology RAB7A antibody (Cell Signaling Technology, D95F2) was used in immunocytochemistry on mouse samples . PLoS ONE (2014) ncbi
domestic rabbit monoclonal (D95F2)
  • immunocytochemistry; mouse
In order to study the intracellular role of sorcin, Cell Signaling Technology RAB7A antibody (Cell Signaling, D95F2) was used in immunocytochemistry on mouse samples . PLoS ONE (2014) ncbi
domestic rabbit monoclonal (D95F2)
  • immunocytochemistry knockout validation; mouse; fig 1
  • western blot knockout validation; mouse; fig 1
  • flow cytometry; mouse; fig 1
Cell Signaling Technology RAB7A antibody (Cell Signaling, 9367) was used in immunocytochemistry knockout validation on mouse samples (fig 1), in western blot knockout validation on mouse samples (fig 1) and in flow cytometry on mouse samples (fig 1). Autophagy (2013) ncbi
MilliporeSigma
mouse monoclonal (Rab7-117)
  • western blot; mouse; loading ...
MilliporeSigma RAB7A antibody (Sigma-aldrich, R8779) was used in western blot on mouse samples . Acta Neuropathol Commun (2021) ncbi
mouse monoclonal (Rab7-117)
  • western blot; human; 1 ug/ml; fig s1a
MilliporeSigma RAB7A antibody (Sigma, R8779) was used in western blot on human samples at 1 ug/ml (fig s1a). Acta Neuropathol (2021) ncbi
mouse monoclonal (Rab7-117)
  • western blot; mouse; loading ...; fig 1d
MilliporeSigma RAB7A antibody (Sigma, R8779) was used in western blot on mouse samples (fig 1d). Sci Rep (2021) ncbi
Addgene
In order to determine the role of PICALM in Abeta transcytosis across the blood brain barrier, Addgene RAB7A antibody (Addgene, 12660) was used . Nat Neurosci (2015) ncbi
Articles Reviewed
  1. Han X, Wang C, Song L, Wang X, Tang S, Hou T, et al. KIBRA regulates amyloid β metabolism by controlling extracellular vesicles secretion. EBioMedicine. 2022;78:103980 pubmed publisher
  2. Sun J, Liu Y, Hao X, Lin W, Su W, Chiang E, et al. LAMTOR1 inhibition of TRPML1-dependent lysosomal calcium release regulates dendritic lysosome trafficking and hippocampal neuronal function. EMBO J. 2022;41:e108119 pubmed publisher
  3. Simoes S, Guo J, Buitrago L, Qureshi Y, Feng X, Kothiya M, et al. Alzheimer's vulnerable brain region relies on a distinct retromer core dedicated to endosomal recycling. Cell Rep. 2021;37:110182 pubmed publisher
  4. Deluco B, Wilson H. Assessment of intestinal macromolecular absorption in young piglets to pave the way to oral vaccination: preliminary results. Vet Res Commun. 2022;46:79-91 pubmed publisher
  5. Jeong A, Cheng S, Zhong R, Bennett D, Bergo M, Li L. Protein farnesylation is upregulated in Alzheimer's human brains and neuron-specific suppression of farnesyltransferase mitigates pathogenic processes in Alzheimer's model mice. Acta Neuropathol Commun. 2021;9:129 pubmed publisher
  6. Mathieu M, Nevo N, Jouve M, Valenzuela J, Maurin M, Verweij F, et al. Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9. Nat Commun. 2021;12:4389 pubmed publisher
  7. Fan Y, Nirujogi R, Garrido A, Ruiz Martinez J, Bergareche Yarza A, Mondragón Rezola E, et al. R1441G but not G2019S mutation enhances LRRK2 mediated Rab10 phosphorylation in human peripheral blood neutrophils. Acta Neuropathol. 2021;142:475-494 pubmed publisher
  8. Iwama H, Mehanna S, Imasaka M, Hashidume S, Nishiura H, Yamamura K, et al. Cathepsin B and D deficiency in the mouse pancreas induces impaired autophagy and chronic pancreatitis. Sci Rep. 2021;11:6596 pubmed publisher
  9. He Y, Kan W, Li Y, Hao Y, Huang A, Gu H, et al. A potent and selective small molecule inhibitor of myoferlin attenuates colorectal cancer progression. Clin Transl Med. 2021;11:e289 pubmed publisher
  10. Affortit C, Casas F, Ladrech S, Ceccato J, Bourien J, Coyat C, et al. Exacerbated age-related hearing loss in mice lacking the p43 mitochondrial T3 receptor. BMC Biol. 2021;19:18 pubmed publisher
  11. Polanco J, Hand G, Briner A, Li C, Götz J. Exosomes induce endolysosomal permeabilization as a gateway by which exosomal tau seeds escape into the cytosol. Acta Neuropathol. 2021;141:235-256 pubmed publisher
  12. Daniloski Z, Jordan T, Wessels H, Hoagland D, Kasela S, Legut M, et al. Identification of Required Host Factors for SARS-CoV-2 Infection in Human Cells. Cell. 2021;184:92-105.e16 pubmed publisher
  13. Bhat O, Yuan X, Camus S, Salloum F, Li P. Abnormal Lysosomal Positioning and Small Extracellular Vesicle Secretion in Arterial Stiffening and Calcification of Mice Lacking Mucolipin 1 Gene. Int J Mol Sci. 2020;21: pubmed publisher
  14. Kucharava K, Brand Y, Albano G, Sekulic Jablanovic M, Glutz A, Xian X, et al. Sodium-hydrogen exchanger 6 (NHE6) deficiency leads to hearing loss, via reduced endosomal signalling through the BDNF/Trk pathway. Sci Rep. 2020;10:3609 pubmed publisher
  15. Jaynes J, Sable R, Ronzetti M, Bautista W, Knotts Z, Abisoye Ogunniyan A, et al. Mannose receptor (CD206) activation in tumor-associated macrophages enhances adaptive and innate antitumor immune responses. Sci Transl Med. 2020;12: pubmed publisher
  16. Deng M, Chen Z, Tan J, Liu H. Down-regulation of SLC35C1 induces colon cancer through over-activating Wnt pathway. J Cell Mol Med. 2020;24:3079-3090 pubmed publisher
  17. Zhang S, Hu L, Jiang J, Li H, Wu Q, Ooi K, et al. HMGB1/RAGE axis mediates stress-induced RVLM neuroinflammation in mice via impairing mitophagy flux in microglia. J Neuroinflammation. 2020;17:15 pubmed publisher
  18. Palomo Guerrero M, Fadó R, Casas M, Pérez Montero M, Baena M, Helmer P, et al. Sensing of nutrients by CPT1C regulates late endosome/lysosome anterograde transport and axon growth. elife. 2019;8: pubmed publisher
  19. Ramírez C, Hauser A, Vucic E, Bar Sagi D. Plasma membrane V-ATPase controls oncogenic RAS-induced macropinocytosis. Nature. 2019;576:477-481 pubmed publisher
  20. Lu Y, Zheng Y, Coyaud E, Zhang C, Selvabaskaran A, Yu Y, et al. Palmitoylation of NOD1 and NOD2 is required for bacterial sensing. Science. 2019;366:460-467 pubmed publisher
  21. Xiong X, Lee C, Li W, Yu J, Zhu L, Kim Y, et al. Acid Sphingomyelinase regulates the localization and trafficking of palmitoylated proteins. Biol Open. 2019;: pubmed publisher
  22. von Gamm M, Schaub A, Jones A, Wolf C, Behrens G, Lichti J, et al. Immune homeostasis and regulation of the interferon pathway require myeloid-derived Regnase-3. J Exp Med. 2019;: pubmed publisher
  23. Sahgal P, Alanko J, Icha J, Paatero I, Hamidi H, Arjonen A, et al. GGA2 and RAB13 promote activity-dependent β1-integrin recycling. J Cell Sci. 2019;132: pubmed publisher
  24. Guo M, Hartlova A, Gierlinski M, Prescott A, Castellvi J, Losa J, et al. Triggering MSR1 promotes JNK-mediated inflammation in IL-4-activated macrophages. EMBO J. 2019;38: pubmed publisher
  25. Jeppesen D, Fenix A, Franklin J, Higginbotham J, Zhang Q, Zimmerman L, et al. Reassessment of Exosome Composition. Cell. 2019;177:428-445.e18 pubmed publisher
  26. Sapmaz A, Berlin I, Bos E, Wijdeven R, Janssen H, Konietzny R, et al. USP32 regulates late endosomal transport and recycling through deubiquitylation of Rab7. Nat Commun. 2019;10:1454 pubmed publisher
  27. Valoskova K, Biebl J, Roblek M, Emtenani S, Gyoergy A, Misova M, et al. A conserved major facilitator superfamily member orchestrates a subset of O-glycosylation to aid macrophage tissue invasion. elife. 2019;8: pubmed publisher
  28. Bae D, Moore K, Mella J, Hayashi S, Hollien J. Degradation of Blos1 mRNA by IRE1 repositions lysosomes and protects cells from stress. J Cell Biol. 2019;218:1118-1127 pubmed publisher
  29. Yeshaw W, van der Zwaag M, Pinto F, Lahaye L, Faber A, Gómez Sánchez R, et al. Human VPS13A is associated with multiple organelles and influences mitochondrial morphology and lipid droplet motility. elife. 2019;8: pubmed publisher
  30. Mason D, Collins J, Dawahare J, Nguyen T, Lin Y, Voytik Harbin S, et al. YAP and TAZ limit cytoskeletal and focal adhesion maturation to enable persistent cell motility. J Cell Biol. 2019;218:1369-1389 pubmed publisher
  31. Swain S, Roe M, Sebrell T, Sidar B, Dankoff J, VanAusdol R, et al. CD103 (αE Integrin) Undergoes Endosomal Trafficking in Human Dendritic Cells, but Does Not Mediate Epithelial Adhesion. Front Immunol. 2018;9:2989 pubmed publisher
  32. Keklikoglou I, Cianciaruso C, Güç E, Squadrito M, Spring L, Tazzyman S, et al. Chemotherapy elicits pro-metastatic extracellular vesicles in breast cancer models. Nat Cell Biol. 2019;21:190-202 pubmed publisher
  33. Atakpa P, Thillaiappan N, Mataragka S, Prole D, Taylor C. IP3 Receptors Preferentially Associate with ER-Lysosome Contact Sites and Selectively Deliver Ca2+ to Lysosomes. Cell Rep. 2018;25:3180-3193.e7 pubmed publisher
  34. Theisen D, Davidson J, Briseño C, Gargaro M, Lauron E, Wang Q, et al. WDFY4 is required for cross-presentation in response to viral and tumor antigens. Science. 2018;362:694-699 pubmed publisher
  35. Xu X, Xu J, Wu J, Hu Y, Han Y, Gu Y, et al. Phosphorylation-Mediated IFN-γR2 Membrane Translocation Is Required to Activate Macrophage Innate Response. Cell. 2018;175:1336-1351.e17 pubmed publisher
  36. Alissafi T, Hatzioannou A, Mintzas K, Barouni R, Banos A, Sormendi S, et al. Autophagy orchestrates the regulatory program of tumor-associated myeloid-derived suppressor cells. J Clin Invest. 2018;128:3840-3852 pubmed publisher
  37. Hartlova A, Herbst S, Peltier J, Rodgers A, Bilkei Gorzo O, Fearns A, et al. LRRK2 is a negative regulator of Mycobacterium tuberculosis phagosome maturation in macrophages. EMBO J. 2018;37: pubmed publisher
  38. Lim J, Lim J, Kim G, Levine R. Myristoylated methionine sulfoxide reductase A is a late endosomal protein. J Biol Chem. 2018;293:7355-7366 pubmed publisher
  39. Jimenez Orgaz A, Kvainickas A, Nägele H, Denner J, Eimer S, Dengjel J, et al. Control of RAB7 activity and localization through the retromer-TBC1D5 complex enables RAB7-dependent mitophagy. EMBO J. 2018;37:235-254 pubmed publisher
  40. Gulbranson D, Davis E, Demmitt B, Ouyang Y, Ye Y, Yu H, et al. RABIF/MSS4 is a Rab-stabilizing holdase chaperone required for GLUT4 exocytosis. Proc Natl Acad Sci U S A. 2017;114:E8224-E8233 pubmed publisher
  41. Rocchi A, Yamamoto S, Ting T, Fan Y, SADLEIR K, Wang Y, et al. A Becn1 mutation mediates hyperactive autophagic sequestration of amyloid oligomers and improved cognition in Alzheimer's disease. PLoS Genet. 2017;13:e1006962 pubmed publisher
  42. Zhang X, Jiang S, Mitok K, Li L, Attie A, Martin T. BAIAP3, a C2 domain-containing Munc13 protein, controls the fate of dense-core vesicles in neuroendocrine cells. J Cell Biol. 2017;216:2151-2166 pubmed publisher
  43. Drake M, Brennan B, Briley K, Bart S, Sherman E, Szemiel A, et al. A role for glycolipid biosynthesis in severe fever with thrombocytopenia syndrome virus entry. PLoS Pathog. 2017;13:e1006316 pubmed publisher
  44. Marwaha R, Arya S, Jagga D, Kaur H, Tuli A, Sharma M. The Rab7 effector PLEKHM1 binds Arl8b to promote cargo traffic to lysosomes. J Cell Biol. 2017;216:1051-1070 pubmed publisher
  45. Kober A, Manavalan A, Tam Amersdorfer C, Holmér A, Saeed A, Fanaee Danesh E, et al. Implications of cerebrovascular ATP-binding cassette transporter G1 (ABCG1) and apolipoprotein M in cholesterol transport at the blood-brain barrier. Biochim Biophys Acta Mol Cell Biol Lipids. 2017;1862:573-588 pubmed publisher
  46. Peng M, Yin N, Li M. SZT2 dictates GATOR control of mTORC1 signalling. Nature. 2017;543:433-437 pubmed publisher
  47. Hammerling B, Najor R, Cortez M, Shires S, Leon L, Gonzalez E, et al. A Rab5 endosomal pathway mediates Parkin-dependent mitochondrial clearance. Nat Commun. 2017;8:14050 pubmed publisher
  48. Luo Y, Duan H, Qian Y, Feng L, Wu Z, Wang F, et al. Macrophagic CD146 promotes foam cell formation and retention during atherosclerosis. Cell Res. 2017;27:352-372 pubmed publisher
  49. Shi B, Huang Q, Birkett R, Doyle R, Dorfleutner A, Stehlik C, et al. SNAPIN is critical for lysosomal acidification and autophagosome maturation in macrophages. Autophagy. 2017;13:285-301 pubmed publisher
  50. Lucitti J, Sealock R, Buckley B, Zhang H, Xiao L, Dudley A, et al. Variants of Rab GTPase-Effector Binding Protein-2 Cause Variation in the Collateral Circulation and Severity of Stroke. Stroke. 2016;47:3022-3031 pubmed
  51. Benkafadar N, Menardo J, Bourien J, Nouvian R, François F, Decaudin D, et al. Reversible p53 inhibition prevents cisplatin ototoxicity without blocking chemotherapeutic efficacy. EMBO Mol Med. 2017;9:7-26 pubmed publisher
  52. Jaber N, Mohd Naim N, Wang Z, Deleon J, Kim S, Zhong H, et al. Vps34 regulates Rab7 and late endocytic trafficking through recruitment of the GTPase-activating protein Armus. J Cell Sci. 2016;129:4424-4435 pubmed
  53. Kumar B, Dutta D, Iqbal J, Ansari M, Roy A, Chikoti L, et al. ESCRT-I Protein Tsg101 Plays a Role in the Post-macropinocytic Trafficking and Infection of Endothelial Cells by Kaposi's Sarcoma-Associated Herpesvirus. PLoS Pathog. 2016;12:e1005960 pubmed publisher
  54. Rofe A, Davis L, Whittingham J, Latimer Bowman E, Wilkinson A, Pryor P. The Rhodococcus equi virulence protein VapA disrupts endolysosome function and stimulates lysosome biogenesis. Microbiologyopen. 2017;6: pubmed publisher
  55. Fujii N, Matsuo Y, Matsunaga T, Endo S, Sakai H, Yamaguchi M, et al. Hypotonic Stress-induced Down-regulation of Claudin-1 and -2 Mediated by Dephosphorylation and Clathrin-dependent Endocytosis in Renal Tubular Epithelial Cells. J Biol Chem. 2016;291:24787-24799 pubmed
  56. Vanhoutte D, Schips T, Kwong J, Davis J, Tjondrokoesoemo A, Brody M, et al. Thrombospondin expression in myofibers stabilizes muscle membranes. elife. 2016;5: pubmed publisher
  57. Hubert V, Peschel A, Langer B, Groger M, Rees A, Kain R. LAMP-2 is required for incorporating syntaxin-17 into autophagosomes and for their fusion with lysosomes. Biol Open. 2016;5:1516-1529 pubmed publisher
  58. Chaubey P, Hofstetter L, Roschitzki B, Stieger B. Proteomic Analysis of the Rat Canalicular Membrane Reveals Expression of a Complex System of P4-ATPases in Liver. PLoS ONE. 2016;11:e0158033 pubmed publisher
  59. Marquer C, Tian H, Yi J, Bastien J, Dall Armi C, Yang Klingler Y, et al. Arf6 controls retromer traffic and intracellular cholesterol distribution via a phosphoinositide-based mechanism. Nat Commun. 2016;7:11919 pubmed publisher
  60. Wijdeven R, Janssen H, Nahidiazar L, Janssen L, Jalink K, Berlin I, et al. Cholesterol and ORP1L-mediated ER contact sites control autophagosome transport and fusion with the endocytic pathway. Nat Commun. 2016;7:11808 pubmed publisher
  61. Wu L, Sun Y, Ma L, Zhu J, Zhang B, Pan Q, et al. A C-terminally truncated mouse Best3 splice variant targets and alters the ion balance in lysosome-endosome hybrids and the endoplasmic reticulum. Sci Rep. 2016;6:27332 pubmed publisher
  62. Kajiho H, Kajiho Y, Frittoli E, Confalonieri S, Bertalot G, Viale G, et al. RAB2A controls MT1-MMP endocytic and E-cadherin polarized Golgi trafficking to promote invasive breast cancer programs. EMBO Rep. 2016;17:1061-80 pubmed publisher
  63. Wang Y, Hu C, Li J, You X, Gao F. Increased translocation of antigens to endosomes and TLR4 mediated endosomal recruitment of TAP contribute to nicotine augmented cross-presentation. Oncotarget. 2016;7:38451-38466 pubmed publisher
  64. Scharn C, Collins A, Nair V, Stamm C, MARCIANO D, Graviss E, et al. Heme Oxygenase-1 Regulates Inflammation and Mycobacterial Survival in Human Macrophages during Mycobacterium tuberculosis Infection. J Immunol. 2016;196:4641-9 pubmed publisher
  65. Starling G, Yip Y, Sanger A, Morton P, Eden E, Dodding M. Folliculin directs the formation of a Rab34-RILP complex to control the nutrient-dependent dynamic distribution of lysosomes. EMBO Rep. 2016;17:823-41 pubmed publisher
  66. Boothe T, Lim G, Cen H, Skovsø S, Piske M, Li S, et al. Inter-domain tagging implicates caveolin-1 in insulin receptor trafficking and Erk signaling bias in pancreatic beta-cells. Mol Metab. 2016;5:366-378 pubmed publisher
  67. Sellier C, Campanari M, Julie Corbier C, Gaucherot A, Kolb Cheynel I, Oulad Abdelghani M, et al. Loss of C9ORF72 impairs autophagy and synergizes with polyQ Ataxin-2 to induce motor neuron dysfunction and cell death. EMBO J. 2016;35:1276-97 pubmed publisher
  68. Kurkinen K, Marttinen M, Turner L, Natunen T, Mäkinen P, Haapalinna F, et al. SEPT8 modulates ?-amyloidogenic processing of APP by affecting the sorting and accumulation of BACE1. J Cell Sci. 2016;129:2224-38 pubmed publisher
  69. Jiang H, Zhang X, Lin H. Lysine fatty acylation promotes lysosomal targeting of TNF-?. Sci Rep. 2016;6:24371 pubmed publisher
  70. Aizawa S, Fujiwara Y, Contu V, Hase K, Takahashi M, Kikuchi H, et al. Lysosomal putative RNA transporter SIDT2 mediates direct uptake of RNA by lysosomes. Autophagy. 2016;12:565-78 pubmed publisher
  71. Gschweitl M, Ulbricht A, Barnes C, Enchev R, Stoffel Studer I, Meyer Schaller N, et al. A SPOPL/Cullin-3 ubiquitin ligase complex regulates endocytic trafficking by targeting EPS15 at endosomes. elife. 2016;5:e13841 pubmed publisher
  72. Lisewski U, Koehncke C, Wilck N, Buschmeyer B, Pieske B, Roepke T. Increased aldosterone-dependent Kv1.5 recycling predisposes to pacing-induced atrial fibrillation in Kcne3-/- mice. FASEB J. 2016;30:2476-89 pubmed publisher
  73. Clifford R, Maryon E, Kaplan J. Dynamic internalization and recycling of a metal ion transporter: Cu homeostasis and CTR1, the human Cu⁺ uptake system. J Cell Sci. 2016;129:1711-21 pubmed publisher
  74. Ouimet M, Hennessy E, van Solingen C, Koelwyn G, Hussein M, Ramkhelawon B, et al. miRNA Targeting of Oxysterol-Binding Protein-Like 6 Regulates Cholesterol Trafficking and Efflux. Arterioscler Thromb Vasc Biol. 2016;36:942-951 pubmed publisher
  75. Brahic M, Bousset L, Bieri G, Melki R, Gitler A. Axonal transport and secretion of fibrillar forms of α-synuclein, Aβ42 peptide and HTTExon 1. Acta Neuropathol. 2016;131:539-48 pubmed publisher
  76. Ketel K, Krauss M, Nicot A, Puchkov D, Wieffer M, Müller R, et al. A phosphoinositide conversion mechanism for exit from endosomes. Nature. 2016;529:408-12 pubmed publisher
  77. Wu B, Yu L, Wang Y, Wang H, Li C, Yin Y, et al. Aldehyde dehydrogenase 2 activation in aged heart improves the autophagy by reducing the carbonyl modification on SIRT1. Oncotarget. 2016;7:2175-88 pubmed publisher
  78. Drusenheimer N, Migdal B, Jäckel S, Tveriakhina L, Scheider K, Schulz K, et al. The Mammalian Orthologs of Drosophila Lgd, CC2D1A and CC2D1B, Function in the Endocytic Pathway, but Their Individual Loss of Function Does Not Affect Notch Signalling. PLoS Genet. 2015;11:e1005749 pubmed publisher
  79. He J, Johnson J, Monfregola J, Ramadass M, Pestonjamasp K, Napolitano G, et al. Munc13-4 interacts with syntaxin 7 and regulates late endosomal maturation, endosomal signaling, and TLR9-initiated cellular responses. Mol Biol Cell. 2016;27:572-87 pubmed publisher
  80. Chrisam M, Pirozzi M, Castagnaro S, Blaauw B, Polishchuck R, Cecconi F, et al. Reactivation of autophagy by spermidine ameliorates the myopathic defects of collagen VI-null mice. Autophagy. 2015;11:2142-52 pubmed publisher
  81. Chaumet A, Wright G, Seet S, Tham K, Gounko N, Bard F. Nuclear envelope-associated endosomes deliver surface proteins to the nucleus. Nat Commun. 2015;6:8218 pubmed publisher
  82. Hong N, Qi A, Weaver A. PI(3,5)P2 controls endosomal branched actin dynamics by regulating cortactin-actin interactions. J Cell Biol. 2015;210:753-69 pubmed publisher
  83. Chichger H, Braza J, Duong H, Stark M, Harrington E. Neovascularization in the pulmonary endothelium is regulated by the endosome: Rab4-mediated trafficking and p18-dependent signaling. Am J Physiol Lung Cell Mol Physiol. 2015;309:L700-9 pubmed publisher
  84. Zhao Z, Sagare A, Ma Q, Halliday M, Kong P, Kisler K, et al. Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance. Nat Neurosci. 2015;18:978-87 pubmed publisher
  85. La Rosa L, Perrone L, Nielsen M, Calissano P, Andersen O, Matrone C. Y682G Mutation of Amyloid Precursor Protein Promotes Endo-Lysosomal Dysfunction by Disrupting APP-SorLA Interaction. Front Cell Neurosci. 2015;9:109 pubmed publisher
  86. Pone E, Lam T, Lou Z, Wang R, Chen Y, Liu D, et al. B cell Rab7 mediates induction of activation-induced cytidine deaminase expression and class-switching in T-dependent and T-independent antibody responses. J Immunol. 2015;194:3065-78 pubmed publisher
  87. Lim J, Lachenmayer M, Wu S, Liu W, Kundu M, Wang R, et al. Proteotoxic stress induces phosphorylation of p62/SQSTM1 by ULK1 to regulate selective autophagic clearance of protein aggregates. PLoS Genet. 2015;11:e1004987 pubmed publisher
  88. Fields J, Dumaop W, Eleuteri S, Elueteri S, Campos S, Serger E, et al. HIV-1 Tat alters neuronal autophagy by modulating autophagosome fusion to the lysosome: implications for HIV-associated neurocognitive disorders. J Neurosci. 2015;35:1921-38 pubmed publisher
  89. Herbst S, Shah A, Mazon Moya M, Marzola V, Jensen B, Reed A, et al. Phagocytosis-dependent activation of a TLR9-BTK-calcineurin-NFAT pathway co-ordinates innate immunity to Aspergillus fumigatus. EMBO Mol Med. 2015;7:240-58 pubmed publisher
  90. Kizuka Y, Kitazume S, Fujinawa R, Saito T, Iwata N, Saido T, et al. An aberrant sugar modification of BACE1 blocks its lysosomal targeting in Alzheimer's disease. EMBO Mol Med. 2015;7:175-89 pubmed publisher
  91. Bunse L, Schumacher T, Sahm F, Pusch S, Oezen I, Rauschenbach K, et al. Proximity ligation assay evaluates IDH1R132H presentation in gliomas. J Clin Invest. 2015;125:593-606 pubmed publisher
  92. Nonnenmacher M, Cintrat J, Gillet D, Weber T. Syntaxin 5-dependent retrograde transport to the trans-Golgi network is required for adeno-associated virus transduction. J Virol. 2015;89:1673-87 pubmed publisher
  93. Lou J, Low Nam S, Kerkvliet J, Hoppe A. Delivery of CSF-1R to the lumen of macropinosomes promotes its destruction in macrophages. J Cell Sci. 2014;127:5228-39 pubmed publisher
  94. Rai S, Tanaka H, Suzuki M, Ogoh H, Taniguchi Y, Morita Y, et al. Clathrin assembly protein CALM plays a critical role in KIT signaling by regulating its cellular transport from early to late endosomes in hematopoietic cells. PLoS ONE. 2014;9:e109441 pubmed publisher
  95. Chen K, Wang C, Tsai M, Wu C, Yang H, Chen L, et al. Interconnections between autophagy and the coagulation cascade in hepatocellular carcinoma. Cell Death Dis. 2014;5:e1244 pubmed publisher
  96. Farg M, Sundaramoorthy V, Sultana J, Yang S, Atkinson R, Levina V, et al. C9ORF72, implicated in amytrophic lateral sclerosis and frontotemporal dementia, regulates endosomal trafficking. Hum Mol Genet. 2014;23:3579-95 pubmed publisher
  97. Lalioti V, Ilari A, O Connell D, Poser E, Sandoval I, Colotti G. Sorcin links calcium signaling to vesicle trafficking, regulates Polo-like kinase 1 and is necessary for mitosis. PLoS ONE. 2014;9:e85438 pubmed publisher
  98. Roy S, Stevens M, So L, Edinger A. Reciprocal effects of rab7 deletion in activated and neglected T cells. Autophagy. 2013;9:1009-23 pubmed publisher
  99. Vogt D, Camus G, Herker E, Webster B, Tsou C, Greene W, et al. Lipid droplet-binding protein TIP47 regulates hepatitis C Virus RNA replication through interaction with the viral NS5A protein. PLoS Pathog. 2013;9:e1003302 pubmed publisher
  100. Wu H, Downs D, Ghosh K, Ghosh A, Staib P, Monod M, et al. Candida albicans secreted aspartic proteases 4-6 induce apoptosis of epithelial cells by a novel Trojan horse mechanism. FASEB J. 2013;27:2132-44 pubmed publisher
  101. Cho K, Park J, Piggott A, Salim A, Gorfe A, Parton R, et al. Staurosporines disrupt phosphatidylserine trafficking and mislocalize Ras proteins. J Biol Chem. 2012;287:43573-84 pubmed publisher