This is a Validated Antibody Database (VAD) review about human Prox1, based on 20 published articles (read how Labome selects the articles), using Prox1 antibody in all methods. It is aimed to help Labome visitors find the most suited Prox1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Abcam
domestic rabbit monoclonal (EPR19273)
  • immunohistochemistry - frozen section; mouse; 1:500; loading ...; fig 2k, s4a
Abcam Prox1 antibody (Abcam, ab199359) was used in immunohistochemistry - frozen section on mouse samples at 1:500 (fig 2k, s4a). Nat Commun (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; loading ...; fig 1c
Abcam Prox1 antibody (Abcam, ab101851) was used in immunohistochemistry - frozen section on mouse samples (fig 1c). elife (2021) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; mouse; 1:500; loading ...; fig 2a
Abcam Prox1 antibody (Abcam, ab101851) was used in immunocytochemistry on mouse samples at 1:500 (fig 2a). Transl Psychiatry (2021) ncbi
domestic rabbit monoclonal (EPR19273)
  • immunohistochemistry - paraffin section; mouse; 1:500; loading ...; fig s3e
Abcam Prox1 antibody (Abcam, ab199359) was used in immunohistochemistry - paraffin section on mouse samples at 1:500 (fig s3e). Acta Neuropathol Commun (2019) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; 1:200; loading ...; fig 3b
Abcam Prox1 antibody (Abcam, ab38692) was used in immunohistochemistry on mouse samples at 1:200 (fig 3b). Acta Neuropathol (2020) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; 1:200; fig s5
In order to analyze Crim1 regulations of integrin signaling in lens development of mice, Abcam Prox1 antibody (Abcam, ab38692) was used in immunohistochemistry on mouse samples at 1:200 (fig s5). Development (2016) ncbi
R&D Systems
domestic goat polyclonal
  • immunohistochemistry - frozen section; mouse; 1:1000; loading ...; fig 1c
R&D Systems Prox1 antibody (R&D, AF2727) was used in immunohistochemistry - frozen section on mouse samples at 1:1000 (fig 1c). J Neurosci (2021) ncbi
domestic goat polyclonal
  • immunohistochemistry; mouse; 1:40; loading ...; fig 3e
R&D Systems Prox1 antibody (R&D Systems, AF2727) was used in immunohistochemistry on mouse samples at 1:40 (fig 3e). Eneuro (2021) ncbi
domestic goat polyclonal
  • immunohistochemistry; mouse; 1:200; loading ...; fig 4a
R&D Systems Prox1 antibody (R&D Systems, AF2727) was used in immunohistochemistry on mouse samples at 1:200 (fig 4a). iScience (2021) ncbi
BioLegend
domestic rabbit polyclonal (Poly19252)
  • immunohistochemistry; mouse; 1:1000; loading ...; fig 3e
BioLegend Prox1 antibody (Covance, PRB-238C) was used in immunohistochemistry on mouse samples at 1:1000 (fig 3e). Eneuro (2021) ncbi
domestic rabbit polyclonal (Poly19252)
  • immunohistochemistry - frozen section; mouse; 1:500; loading ...; fig 5s1
BioLegend Prox1 antibody (Covance, PRB-238C) was used in immunohistochemistry - frozen section on mouse samples at 1:500 (fig 5s1). elife (2019) ncbi
domestic rabbit polyclonal (Poly19252)
  • immunohistochemistry; human; fig s5f, s5g
BioLegend Prox1 antibody (BioLegend, 925201) was used in immunohistochemistry on human samples (fig s5f, s5g). Cancer Res (2019) ncbi
Angiobio
  • immunohistochemistry; mouse; 1:200; loading ...; fig 4a
Angiobio Prox1 antibody (AngioBio, 11-002) was used in immunohistochemistry on mouse samples at 1:200 (fig 4a). iScience (2021) ncbi
  • immunohistochemistry; mouse; 1:500; loading ...; fig 1j, 2c, 2k
Angiobio Prox1 antibody (Angiobio, 11-002 P) was used in immunohistochemistry on mouse samples at 1:500 (fig 1j, 2c, 2k). Nat Commun (2020) ncbi
  • immunohistochemistry; zebrafish ; 1:500; loading ...; fig 3f
Angiobio Prox1 antibody (AngioBio, 11-C002) was used in immunohistochemistry on zebrafish samples at 1:500 (fig 3f). elife (2019) ncbi
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 5f
In order to develop an in vitro method to generate a 3D human lymphatic network within native connective tissue devoid of any exogenous material, Angiobio Prox1 antibody (AngioBio, 11-002) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 5f). Nat Protoc (2017) ncbi
  • immunohistochemistry; mouse; loading ...; fig 2j
In order to examine the role of metabolism in lymphatic development, Angiobio Prox1 antibody (Angiobio, 11002P) was used in immunohistochemistry on mouse samples (fig 2j). Nature (2017) ncbi
  • immunohistochemistry; mouse; 1:200; loading ...; fig 2a
In order to report that SDC4 governs flow-induced lymphatic endothelial cell polarization via regulation of VANGL2 expression, Angiobio Prox1 antibody (AngioBio, 11002) was used in immunohistochemistry on mouse samples at 1:200 (fig 2a). Development (2016) ncbi
  • immunohistochemistry - frozen section; mouse; loading ...; fig s1e
In order to find that cystogenesis is associated with a disorganized pericystic network of vessels expressing platelet/endothelial cell adhesion molecule 1 and vascular endothelial growth factor receptor 3, Angiobio Prox1 antibody (AngioBio, 11-022) was used in immunohistochemistry - frozen section on mouse samples (fig s1e). J Am Soc Nephrol (2016) ncbi
  • immunohistochemistry - frozen section; mouse; 1:500; fig 2
In order to investigate the mechanisms that regulate the entrance and exit of immune cells from the central nervous system, Angiobio Prox1 antibody (Angiobio, 11-002) was used in immunohistochemistry - frozen section on mouse samples at 1:500 (fig 2). Nature (2015) ncbi
  • immunohistochemistry; mouse; 1:200; fig 1
Angiobio Prox1 antibody (AngioBio, 11-002) was used in immunohistochemistry on mouse samples at 1:200 (fig 1). Nature (2015) ncbi
MilliporeSigma
mouse monoclonal (4G10)
  • immunoprecipitation; mouse; 0.25 ug/mL
In order to study the role of integrin alpha-3 in maintaining neuronal stability, MilliporeSigma Prox1 antibody (Sigma, 4G10) was used in immunoprecipitation on mouse samples at 0.25 ug/mL. J Neurosci (2013) ncbi
Articles Reviewed
  1. Stachniak T, Kastli R, Hanley O, Argunşah A, van der Valk E, Kanatouris G, et al. Postmitotic Prox1 Expression Controls the Final Specification of Cortical VIP Interneuron Subtypes. J Neurosci. 2021;41:8150-8162 pubmed publisher
  2. Zhang D, Huang J, Sun X, Chen H, Huang S, Yang J, et al. Targeting local lymphatics to ameliorate heterotopic ossification via FGFR3-BMPR1a pathway. Nat Commun. 2021;12:4391 pubmed publisher
  3. Åmellem I, Yovianto G, Chong H, Nair R, Cnops V, Thanawalla A, et al. Role of NMDA Receptors in Adult Neurogenesis and Normal Development of the Dentate Gyrus. Eneuro. 2021;8: pubmed publisher
  4. Johnston S, Parylak S, Kim S, Mac N, Lim C, Gallina I, et al. AAV ablates neurogenesis in the adult murine hippocampus. elife. 2021;10: pubmed publisher
  5. Haan N, Westacott L, Carter J, Owen M, Gray W, Hall J, et al. Haploinsufficiency of the schizophrenia and autism risk gene Cyfip1 causes abnormal postnatal hippocampal neurogenesis through microglial and Arp2/3 mediated actin dependent mechanisms. Transl Psychiatry. 2021;11:313 pubmed publisher
  6. Maruyama K, Naemura K, Arima Y, Uchijima Y, Nagao H, Yoshihara K, et al. Semaphorin3E-PlexinD1 signaling in coronary artery and lymphatic vessel development with clinical implications in myocardial recovery. iScience. 2021;24:102305 pubmed publisher
  7. Tai Nagara I, Hasumi Y, Kusumoto D, Hasumi H, Okabe K, Ando T, et al. Blood and lymphatic systems are segregated by the FLCN tumor suppressor. Nat Commun. 2020;11:6314 pubmed publisher
  8. Schoof M, Launspach M, Holdhof D, Nguyen L, Engel V, Filser S, et al. The transcriptional coactivator and histone acetyltransferase CBP regulates neural precursor cell development and migration. Acta Neuropathol Commun. 2019;7:199 pubmed publisher
  9. Shibata Germanos S, Goodman J, Grieg A, Trivedi C, Benson B, Foti S, et al. Structural and functional conservation of non-lumenized lymphatic endothelial cells in the mammalian leptomeninges. Acta Neuropathol. 2020;139:383-401 pubmed publisher
  10. Prajapati DiNubila M, Benito Gonzalez A, Golden E, Zhang S, Doetzlhofer A. A counter gradient of Activin A and follistatin instructs the timing of hair cell differentiation in the murine cochlea. elife. 2019;8: pubmed publisher
  11. Grimm L, Nakajima H, Chaudhury S, Bower N, Okuda K, Cox A, et al. Yap1 promotes sprouting and proliferation of lymphatic progenitors downstream of Vegfc in the zebrafish trunk. elife. 2019;8: pubmed publisher
  12. Karnezis T, Farnsworth R, Harris N, Williams S, Caesar C, Byrne D, et al. CCL27/CCL28-CCR10 Chemokine Signaling Mediates Migration of Lymphatic Endothelial Cells. Cancer Res. 2019;79:1558-1572 pubmed publisher
  13. Gibot L, Galbraith T, Bourland J, Rogic A, Skobe M, Auger F. Tissue-engineered 3D human lymphatic microvascular network for in vitro studies of lymphangiogenesis. Nat Protoc. 2017;12:1077-1088 pubmed publisher
  14. Wong B, Wang X, Zecchin A, Thienpont B, Cornelissen I, Kalucka J, et al. The role of fatty acid ?-oxidation in lymphangiogenesis. Nature. 2017;542:49-54 pubmed publisher
  15. Wang Y, Baeyens N, Corti F, Tanaka K, Fang J, Zhang J, et al. Syndecan 4 controls lymphatic vasculature remodeling during mouse embryonic development. Development. 2016;143:4441-4451 pubmed
  16. Zhang Y, Fan J, Ho J, Hu T, Kneeland S, Fan X, et al. Crim1 regulates integrin signaling in murine lens development. Development. 2016;143:356-66 pubmed publisher
  17. Huang J, Woolf A, Kolatsi Joannou M, Baluk P, Sandford R, Peters D, et al. Vascular Endothelial Growth Factor C for Polycystic Kidney Diseases. J Am Soc Nephrol. 2016;27:69-77 pubmed publisher
  18. Louveau A, Smirnov I, Keyes T, Eccles J, Rouhani S, Peske J, et al. Structural and functional features of central nervous system lymphatic vessels. Nature. 2015;523:337-41 pubmed publisher
  19. Klotz L, Norman S, Vieira J, Masters M, Rohling M, Dubé K, et al. Cardiac lymphatics are heterogeneous in origin and respond to injury. Nature. 2015;522:62-7 pubmed
  20. Kerrisk M, Greer C, Koleske A. Integrin ?3 is required for late postnatal stability of dendrite arbors, dendritic spines and synapses, and mouse behavior. J Neurosci. 2013;33:6742-52 pubmed publisher