This is a Validated Antibody Database (VAD) review about human PYCR1, based on 2 published articles (read how Labome selects the articles), using PYCR1 antibody in all methods. It is aimed to help Labome visitors find the most suited PYCR1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
PYCR1 synonym: ARCL2B; ARCL3B; P5C; P5CR; PIG45; PP222; PRO3; PYCR; pyrroline-5-carboxylate reductase 1, mitochondrial; P5C reductase 1; proliferation-inducing protein 45

Knockout validation
Proteintech Group
rabbit polyclonal
  • western blot knockout validation; human; 1:1000; fig 2
  • immunohistochemistry - paraffin section; human; fig s5
In order to describe methods to detect restrictive amino acids and measure differential ribosome codon reading, Proteintech Group PYCR1 antibody (Proteintech, 13108-1-AP) was used in western blot knockout validation on human samples at 1:1000 (fig 2) and in immunohistochemistry - paraffin section on human samples (fig s5). Nature (2016) ncbi
Proteintech Group
rabbit polyclonal
  • western blot; human; loading ...; fig 4a
Proteintech Group PYCR1 antibody (Protein Tech, 13108-1-AP) was used in western blot on human samples (fig 4a). Ann Neurol (2016) ncbi
rabbit polyclonal
  • western blot knockout validation; human; 1:1000; fig 2
  • immunohistochemistry - paraffin section; human; fig s5
In order to describe methods to detect restrictive amino acids and measure differential ribosome codon reading, Proteintech Group PYCR1 antibody (Proteintech, 13108-1-AP) was used in western blot knockout validation on human samples at 1:1000 (fig 2) and in immunohistochemistry - paraffin section on human samples (fig s5). Nature (2016) ncbi
Articles Reviewed
  1. Zaki M, Bhat G, Sultan T, Issa M, Jung H, Dikoglu E, et al. PYCR2 Mutations cause a lethal syndrome of microcephaly and failure to thrive. Ann Neurol. 2016;80:59-70 pubmed publisher
  2. Loayza Puch F, Rooijers K, Buil L, Zijlstra J, Oude Vrielink J, Lopes R, et al. Tumour-specific proline vulnerability uncovered by differential ribosome codon reading. Nature. 2016;530:490-4 pubmed publisher